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Aliases for ZNF726 Gene

Aliases for ZNF726 Gene

  • Zinc Finger Protein 726 2 3

External Ids for ZNF726 Gene

Summaries for ZNF726 Gene

GeneCards Summary for ZNF726 Gene

ZNF726 (Zinc Finger Protein 726) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF726 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF726 Gene

Genomics for ZNF726 Gene

Genomic Location for ZNF726 Gene

Start:
23,914,876 bp from pter
End:
23,945,159 bp from pter
Size:
30,284 bases
Orientation:
Plus strand

Genomic View for ZNF726 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF726 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF726 Gene

No data available for Regulatory Elements for ZNF726 Gene

Proteins for ZNF726 Gene

  • Protein details for ZNF726 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNF4-ZN726_HUMAN
    Recommended name:
    Zinc finger protein 726
    Protein Accession:
    A6NNF4
    Secondary Accessions:
    • M0R0X8
    • Q86Y87

    Protein attributes for ZNF726 Gene

    Size:
    738 amino acids
    Molecular mass:
    85539 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF726 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF726 Gene

Proteomics data for ZNF726 Gene at MOPED

Post-translational modifications for ZNF726 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys97 and Lys572

Other Protein References for ZNF726 Gene

No data available for DME Specific Peptides for ZNF726 Gene

Domains for ZNF726 Gene

Gene Families for ZNF726 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF726 Gene

UniProtKB/Swiss-Prot:

ZN726_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • A6NNF4
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • A6NNF4
Similarity:
  • Contains 20 C2H2-type zinc fingers.:
    • A6NNF4
genes like me logo Genes that share domains with ZNF726: view

Function for ZNF726 Gene

Molecular function for ZNF726 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF726 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF726: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF726 Gene

Localization for ZNF726 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF726 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF726 Gene COMPARTMENTS Subcellular localization image for ZNF726 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF726 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF726: view

Pathways for ZNF726 Gene

SuperPathways for ZNF726 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF726: view

Pathways by source for ZNF726 Gene

2 Reactome pathways for ZNF726 Gene

Interacting Proteins for ZNF726 Gene

Gene Ontology (GO) - Biological Process for ZNF726 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF726: view

Transcripts for ZNF726 Gene

mRNA/cDNA for ZNF726 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF726 Gene

Zinc finger protein 726:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF726 Gene

No ASD Table

Relevant External Links for ZNF726 Gene

GeneLoc Exon Structure for
ZNF726
ECgene alternative splicing isoforms for
ZNF726

Expression for ZNF726 Gene

mRNA expression in normal human tissues for ZNF726 Gene

SOURCE GeneReport for Unigene cluster for ZNF726 Gene Hs.655305

genes like me logo Genes that share expressions with ZNF726: view

Orthologs for ZNF726 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF726 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF726 36
  • 93.56 (n)
  • 90.75 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 57 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm9894 37
  • 52 (a)
ManyToMany
Zfp712 36
  • 67.05 (n)
  • 55.9 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 43 (a)
ManyToMany
-- 37
  • 51 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 55 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
-- 37
  • 45 (a)
ManyToMany
-- 37
  • 41 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 33 (a)
ManyToMany
-- 37
  • 31 (a)
ManyToMany
Species with no ortholog for ZNF726:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF726 Gene

ENSEMBL:
Gene Tree for ZNF726 (if available)
TreeFam:
Gene Tree for ZNF726 (if available)

Paralogs for ZNF726 Gene

Selected SIMAP similar genes for ZNF726 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF726: view

Variants for ZNF726 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF726 Gene

Variant ID Type Subtype PubMed ID
esv2751784 CNV Gain 17911159
nsv524183 CNV Gain 19592680
dgv3821n71 CNV Gain 21882294
esv2670676 CNV Deletion 23128226
dgv556e201 CNV Deletion 23290073
esv2662304 CNV Deletion 23128226
esv2633716 CNV Deletion 19546169
esv8359 CNV Loss 19470904
nsv470136 CNV Gain 18288195
nsv458530 CNV Gain 19166990
nsv911476 CNV Gain 21882294

Relevant External Links for ZNF726 Gene

HapMap Linkage Disequilibrium report
ZNF726

No data available for Sequence variations from dbSNP and Humsavar for ZNF726 Gene

Disorders for ZNF726 Gene

No disorders were found for ZNF726 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF726 Gene

Publications for ZNF726 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  3. A scan for positively selected genes in the genomes of humans and chimpanzees. (PMID: 15869325) Nielsen R. … Cargill M. (PLoS Biol. 2005) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF726 Gene

Sources for ZNF726 Gene

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