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Aliases for ZNF726 Gene

Aliases for ZNF726 Gene

  • Zinc Finger Protein 726 2 3 5

External Ids for ZNF726 Gene

Previous GeneCards Identifiers for ZNF726 Gene

  • GC19U900614
  • GC19P023891
  • GC19P024092
  • GC19P023647

Summaries for ZNF726 Gene

GeneCards Summary for ZNF726 Gene

ZNF726 (Zinc Finger Protein 726) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF726 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF726 Gene

Genomics for ZNF726 Gene

Regulatory Elements for ZNF726 Gene

Enhancers for ZNF726 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF726 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF726 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF726 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF726 Gene

23,914,876 bp from pter
23,945,159 bp from pter
30,284 bases
Plus strand

Genomic View for ZNF726 Gene

Genes around ZNF726 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF726 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF726 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF726 Gene

Proteins for ZNF726 Gene

  • Protein details for ZNF726 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 726
    Protein Accession:
    Secondary Accessions:
    • M0R0X8
    • Q86Y87

    Protein attributes for ZNF726 Gene

    738 amino acids
    Molecular mass:
    85539 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF726 Gene


neXtProt entry for ZNF726 Gene

Proteomics data for ZNF726 Gene at MOPED

Post-translational modifications for ZNF726 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF726 Gene

No data available for DME Specific Peptides for ZNF726 Gene

Domains & Families for ZNF726 Gene

Gene Families for ZNF726 Gene

Protein Domains for ZNF726 Gene

Suggested Antigen Peptide Sequences for ZNF726 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 20 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 20 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF726: view

Function for ZNF726 Gene

Molecular function for ZNF726 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF726 Gene

Localization for ZNF726 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF726 Gene

Subcellular locations from

Jensen Localization Image for ZNF726 Gene COMPARTMENTS Subcellular localization image for ZNF726 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF726 Gene

Pathways & Interactions for ZNF726 Gene

SuperPathways for ZNF726 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF726: view

Pathways by source for ZNF726 Gene

2 Reactome pathways for ZNF726 Gene

Interacting Proteins for ZNF726 Gene

Gene Ontology (GO) - Biological Process for ZNF726 Gene


No data available for SIGNOR curated interactions for ZNF726 Gene

Drugs & Compounds for ZNF726 Gene

No Compound Related Data Available

Transcripts for ZNF726 Gene

mRNA/cDNA for ZNF726 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF726 Gene

Zinc finger protein 726:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF726 Gene

No ASD Table

Relevant External Links for ZNF726 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF726 Gene

mRNA expression in normal human tissues for ZNF726 Gene

SOURCE GeneReport for Unigene cluster for ZNF726 Gene Hs.655305

genes like me logo Genes that share expression patterns with ZNF726: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF726 Gene

Orthologs for ZNF726 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF726 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Zfp712 35
  • 67.05 (n)
  • 55.9 (a)
Zfp712 16
Gm9894 36
  • 52 (a)
(Pan troglodytes)
Mammalia ZNF726 35
  • 93.56 (n)
  • 90.75 (a)
(Bos Taurus)
Mammalia -- 36
  • 57 (a)
(Canis familiaris)
Mammalia -- 36
  • 40 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 43 (a)
-- 36
  • 51 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 55 (a)
-- 36
  • 37 (a)
-- 36
  • 45 (a)
-- 36
  • 41 (a)
-- 36
  • 36 (a)
-- 36
  • 35 (a)
-- 36
  • 33 (a)
-- 36
  • 31 (a)
Species with no ortholog for ZNF726:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF726 Gene

Gene Tree for ZNF726 (if available)
Gene Tree for ZNF726 (if available)

Paralogs for ZNF726 Gene

(541) SIMAP similar genes for ZNF726 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF726: view

Variants for ZNF726 Gene

Sequence variations from dbSNP and Humsavar for ZNF726 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8102034 -- 23,914,417(+) aaaaa(A/C)ccaaa upstream-variant-2KB
rs8102419 -- 23,914,530(+) gagcc(G/T)agatc upstream-variant-2KB
rs13343732 -- 23,928,479(+) CTGAT(A/G)TTGTA intron-variant
rs13346132 -- 23,915,294(+) tggga(A/G)gaacg intron-variant
rs67356128 -- 23,917,853(+) ATAAC(-/CT)TAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF726 Gene

Variant ID Type Subtype PubMed ID
esv2751784 CNV Gain 17911159
nsv524183 CNV Gain 19592680
dgv3821n71 CNV Gain 21882294
esv2670676 CNV Deletion 23128226
dgv556e201 CNV Deletion 23290073
esv2662304 CNV Deletion 23128226
esv2633716 CNV Deletion 19546169
esv8359 CNV Loss 19470904
nsv470136 CNV Gain 18288195
nsv458530 CNV Gain 19166990
nsv911476 CNV Gain 21882294

Variation tolerance for ZNF726 Gene

Residual Variation Intolerance Score: 72.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.39; 63.63% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF726 Gene

Disorders for ZNF726 Gene

Relevant External Links for ZNF726

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF726 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF726 Gene

Publications for ZNF726 Gene

  1. A scan for positively selected genes in the genomes of humans and chimpanzees. (PMID: 15869325) Nielsen R. … Cargill M. (PLoS Biol. 2005) 3 67
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF726 Gene

Sources for ZNF726 Gene