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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF724P Gene

pseudogene   GIFtS: 32
GCID: GC19M023404

Zinc Finger Protein 724, Pseudogene

(Previous names: zinc finger protein 724 pseudogene, zinc finger protein...)
  Search for ZNF724P
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 724, Pseudogene1 2
Zinc Finger Protein 724 (Pseudogene)1
Zinc Finger Protein 724 Pseudogene1

External Ids:    HGNC: 324601   Entrez Gene: 4405192   Ensembl: ENSG000001960817   UniProtKB: A8MTY03   

Export aliases for ZNF724P gene to outside databases

Previous GC identifers: GC19M023196 GC19M022945


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF724P Gene: 
ZNF724P (zinc finger protein 724, pseudogene) is a pseudogene. Among its related super-pathways are Gene Expression. GO annotations related to this gene include DNA binding and zinc ion binding. An important paralog of this gene is ZNF420.

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011295.11  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF724P
         Other transcription factors

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   Search SABiosciences Chromatin IP Primers for ZNF724P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF724P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p12   Ensembl cytogenetic band:  19p12   HGNC cytogenetic band: 19p12

ZNF724P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF724P gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M023404:  view genomic region     (about GC identifiers)

Start:
23,404,401 bp from pter      End:
23,433,192 bp from pter
Size:
28,792 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0 (See protein sequence)
Recommended Name: Putative zinc finger protein 724  
Size: 619 amino acids; 71172 Da
Subcellular location: Nucleus (Potential)
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for ZNF724P: NX_A8MTY0

Explore proteomics data for ZNF724P at MOPED 

ZNF724P Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

ZNF724P Protein Expression

ENSEMBL proteins: 
 ENSP00000413411   ENSP00000473253   ENSP00000471547  
Reactome Protein details: A8MTY0
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Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular ----
GO:0005634nucleus IEA--

ZNF724P for ontologies           About GeneDecksing



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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
4 InterPro protein domains:
 IPR015880 Znf_C2H2-like
 IPR001909 Krueppel-associated_box
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry A8MTY0

ProtoNet protein and cluster: A8MTY0

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 16 C2H2-type zinc fingers
Similarity: Contains 1 KRAB domain


ZNF724P for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding ----
GO:0003677DNA binding IEA--
GO:0008270zinc ion binding ----
GO:0046872metal ion binding IEA--
     
ZNF724P for ontologies           About GeneDecksing


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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for ZNF724P About                                                                                                See pathways by source

SuperPathContained pathways About
1Generic Transcription Pathway
Generic Transcription Pathway0.47
Gene Expression0.47

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


2        Reactome Pathways for ZNF724P
    Generic Transcription Pathway
Gene Expression



ZNF724P for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF724P

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for ZNF724P (ENSP000004134114) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CBX5ENSP000002098754STRING: ENSP00000209875
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-dependent IEA--
GO:0006355regulation of transcription, DNA-dependent IEA--

ZNF724P for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF724P (ZN724)

Search CenterWatch for drugs/clinical trials and news about ZNF724P

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for ZNF724P:

Zinc finger protein 724, pseudogene
Hs.675814  [show with all ESTs]
Unigene Representative Sequence: AK301230
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000418100(uc021uru.1) ENST00000597537 ENST00000597037
miRNA
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Additional mRNA sequence: 

AK301230.1 NR_045525.1 

1 DOTS entry:

DT.121501589 

2 AceView cDNA sequences:

BF087114 BQ353521 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF724P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACTAATCCCA
ZNF724P Expression
About this image


See ZNF724P Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.675814
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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZNF724P gene from 1/4 species (see all 4)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
29(a)
1 → many
GL343733.1(125230-159240)
        Species with no ortholog for ZNF724P

ENSEMBL Gene Tree for ZNF724P (if available)
TreeFam Gene Tree for ZNF724P (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for ZNF724P gene
ZNF4202  ZNF780A2  ZNF6652  ZNF72  ZNF232  ZNF4322  ZNF33A2  ZNF2342  
ZNF302  ZNF5732  ZNF4292  ZNF5402  ZNF2512  ZNF6052  ZNF842  ZNF1892  
ZNF5712  ZNF6302  ZNF932  ZNF162  ZNF2832  ZNF3472  ZNF4842  ZNF1352  
ZNF1842  ZNF585B2  ZNF412  ZNF6152  ZNF5692  ZNF4702  
18/519 SIMAP similar genes for ZNF724P using alignment to 3 protein entries:     ZN724_HUMAN (see all proteins) (see all similar genes):
MGC12518    ZNF98    ZNF506    ZNF273    ZNF430    ZNF730
ZNF100    ZNF429    ZNF90    ZNF257    ZNF493    ZNF818P
ZNF728    ZNF93    ZNF66    ZNF738    ZNF675    ZNF726

ZNF724P for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/639 SNPs in ZNF724P are shown (see all 639)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1139127651,2
C,F--23406120(+) ATGTAG/TGGCTT 1 -- ds50012Minor allele frequency- T:0.07CSA WA 120
rs28856041,2
C,F,A--23406165(-) CAATCG/ATCAAC 1 -- ds500112Minor allele frequency- A:0.14NA WA CSA EA 375
rs1447914411,2
--23406303(+) CCAGTA/GTGAAT 1 -- ds50010--------
rs735595521,2
C,F--23406417(+) GTTGAG/AGACAC 1 -- ds50012Minor allele frequency- A:0.12WA 120
rs1176748141,2
C,F--23406418(+) TTGAGG/AACACA 1 -- ds50011Minor allele frequency- A:0.03EA 120
rs1831069281,2
C--23406528(+) CATTCC/TTTACA 1 -- ds50010--------
rs751648061,2
C,F--23406585(+) TTATGA/GAAGTC 1 -- ds50013Minor allele frequency- G:0.08CSA WA 121
rs778778081,2
F--23406738(+) TTTTCA/GTATTT 1 -- nc-transcript-variant1Minor allele frequency- G:0.03WA 118
rs1174732061,2
C,F--23406742(+) CATATT/GTTCTC 1 -- nc-transcript-variant2Minor allele frequency- G:0.07NA EU 714
rs1873927011,2
--23406744(+) TATTTC/TCTCAG 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for ZNF724P (23404401 - 23433192 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ZNF724P: --
SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ZNF724P gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF724P)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 440519 HGNC: 32460 AceView: LOC440519.1 Ensembl:ENSG00000196081 euGenes: HUgn440519
ECgene: ZNF724P H-InvDB: ZNF724P

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for ZNF724P Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for ZNF724P gene:
Search GeneIP for patents involving ZNF724P

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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transforming growth factor, beta 1
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