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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF724P Gene

pseudogene   GIFtS: 32
GCID: GC19M023404

zinc finger protein 724, pseudogene

(Previous names: zinc finger protein 724 pseudogene, zinc finger protein...)
  Search for ZNF724P
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Zinc Finger Protein 724, Pseudogene1 2
Zinc Finger Protein 724 (Pseudogene)1
Zinc Finger Protein 724 Pseudogene1

External Ids:    HGNC: 324601   Entrez Gene: 4405192   Ensembl: ENSG000001960817   UniProtKB: A8MTY03   

Export aliases for ZNF724P gene to outside databases

Previous GC identifers: GC19M023196 GC19M022945


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF724P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ZNF724P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF724P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p12   Ensembl cytogenetic band:  19p12   HGNC cytogenetic band: 19p12

ZNF724P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF724P gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M023404:  view genomic region     (about GC identifiers)

Start:
23,404,401 bp from pter      End:
23,433,172 bp from pter
Size:
28,772 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0 (See protein sequence)
Recommended Name: Putative zinc finger protein 724  
Size: 619 amino acids; 71172 Da
Subcellular location: Nucleus (Potential)
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for ZNF724P: NX_A8MTY0

ZNF724P Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).


ENSEMBL proteins: 
 ENSP00000413411  
Reactome Protein details: A8MTY0
Human Recombinant Protein Products: 
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Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--


ZNF724P for ontologies           About GeneDecksing



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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF724P for domains           About GeneDecksing

4 InterPro domains/families:
 IPR015880 Znf_C2H2-like
 IPR001909 Krueppel-associated_box
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry A8MTY0

ProtoNet protein and cluster: A8MTY0

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 16 C2H2-type zinc fingers
Similarity: Contains 1 KRAB domain


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)

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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding IEA--
GO:0008270zinc ion binding IEA--


ZNF724P for ontologies           About GeneDecksing



(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Generic Transcription Pathway
Generic Transcription Pathway1.00
Gene Expression0.46

Pathway sources
See GeneCards unified pathways
Show all pathways


2        Reactome Pathways for ZNF724P
    Generic Transcription Pathway
Gene Expression



ZNF724P for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF724P

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for ZNF724P (ENSP000004134114) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CBX5ENSP000002098754STRING: ENSP00000209875
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-dependent IEA--
GO:0006355regulation of transcription, DNA-dependent IEA--


ZNF724P for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF724P
Search CenterWatch for drugs/clinical trials and news about ZNF724P 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for ZNF724P:

Zinc finger protein 724, pseudogene
Hs.675814  [show with all ESTs]
Unigene Representative Sequence: AK301230
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000418100(uc021uru.1)

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Inhib. RNA
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Additional cDNA sequence: 

AK301230.1 NR_045525.1 

1 DOTS entry:

DT.121501589 

2 AceView cDNA sequences:

BQ353521 BF087114 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF724P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTAATCCCA

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See ZNF724P Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.675814
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Primer
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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZNF724P gene from 1/4 species (see all 4)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 7)
--
48(a)
45(a)
(see all 7)
many ↔ many
many ↔ many
(see all 7)
GL343330.1(1093706-1292239)
AAWZ02037240(11818-13836)


ENSEMBL Gene Tree for ZNF724P (if available)
TreeFam Gene Tree for ZNF724P (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for ZNF724P gene
ZNF852  ZNF4932  ZNF4862  ZNF1002  ZNF922  ZNF7322  ZNF1382  ZNF6752  
ZNF5062  ZNF2732  ZNF66P2  ZNF6952  ZNF6262  ZNF6802  ZNF2532  ZNF4792  
ZNF932  ZNF4922  ZNF6822  ZNF6762  ZNF1412  ZNF6812  ZNF6792  ZNF2572  
ZNF2542  ZNF7372  ZNF982  ZNF849P2  ZNF7162  ZNF7142  ZNF4292  ZNF4302  
ZNF7302  ZNF6782  ZNF7082  ZNF1172  ZNF1072  ZNF4312  ZNF902  
18/507 SIMAP similar genes for ZNF724P using alignment to 3 protein entries:     ZN724_HUMAN (see all proteins) (see all similar genes):
MGC12518    ZNF66    ZNF738    ZNF273    ZNF818P    ZNF506
ZNF85    DKFZp686M04222    ZFS-6    ZNF708    ZNF93    ZNF254
DKFZp762K012    ZNF429    ZNF431    ZNF492    ZNF675    ZNF78L1

ZNF724P for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/538 NCBI SNPs in ZNF724P are shown (see all 538    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1139127651,2
C,--23406120(+) ATGTAG/TGGCTT 1 -- ds50012Minor allele frequency- T:0.07CSA WA 120
rs28856041,2
C,F,A,--23406165(-) CAATCG/ATCAAC 1 -- ds500112Minor allele frequency- A:0.14NA WA CSA EA 375
rs1447914411,2
--23406303(+) CCAGTA/GTGAAT 1 -- ds50010--------
rs735595521,2
C,--23406417(+) GTTGAG/AGACAC 1 -- ds50012Minor allele frequency- A:0.12WA 120
rs1176748141,2
F,--23406418(+) TTGAGG/AACACA 1 -- ds50011Minor allele frequency- A:0.03EA 120
rs1831069281,2
C,--23406528(+) CATTCC/TTTACA 1 -- ds50010--------
rs751648061,2
--23406585(+) TTATGA/GAAGTC 1 -- ds50013Minor allele frequency- G:0.08CSA WA 121
rs778778081,2
F,--23406738(+) TTTTCA/GTATTT 1 -- nc-transcript-variant1Minor allele frequency- G:0.03WA 118
rs1174732061,2
C,F,--23406742(+) CATATT/GTTCTC 1 -- nc-transcript-variant2Minor allele frequency- G:0.07NA EU 714
rs1873927011,2
--23406744(+) TATTTC/TCTCAG 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for ZNF724P (23404401 - 23433172 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for ZNF724P: --

SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ZNF724P gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF724P)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 440519 HGNC: 32460 AceView: LOC440519.1 Ensembl:ENSG00000196081 euGenes: HUgn440519
ECgene: ZNF724P H-InvDB: ZNF724P

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for ZNF724P Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for ZNF724P gene:
Search GeneIP for patents involving ZNF724P

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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Advanced Cell Diagnostics
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF724P
 Browse SwitchGear 3'UTR luciferase reporter plasmids for ZNF724P
 Browse SwitchGear Promoter luciferase reporter plasmids for ZNF724P
 Search ThermoFisher Antibodies for ZNF724P
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF724P
       
GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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VWF
(GIFTS: 73)
von Willebrand factor
GIFtS Group
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