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ZNF724P Gene

pseudogene   GIFtS: 29
GCID: GC19M023404

Zinc Finger Protein 724, Pseudogene

(Previous names: zinc finger protein 724 pseudogene, zinc finger protein...)
  Search for ZNF724P
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 724, Pseudogene1 2
Zinc Finger Protein 724 (Pseudogene)1
Zinc Finger Protein 724 Pseudogene1

External Ids:    HGNC: 324601   Entrez Gene: 4405192   Ensembl: ENSG000001960817   UniProtKB: A8MTY03   

Export aliases for ZNF724P gene to outside databases

Previous GC identifers: GC19M023196 GC19M022945


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF724P Gene:
ZNF724P (zinc finger protein 724, pseudogene) is a pseudogene. An important paralog of this gene is ZNF85.

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for ZNF724P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF724P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p12   Ensembl cytogenetic band:  19p12   HGNC cytogenetic band: 19p12

ZNF724P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF724P gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M023404:  view genomic region     (about GC identifiers)

Start:
23,404,401 bp from pter      End:
23,433,192 bp from pter
Size:
28,792 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0 (See protein sequence)
Recommended Name: Putative zinc finger protein 724  
Size: 619 amino acids; 71172 Da
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for ZNF724P: NX_A8MTY0

Explore proteomics data for ZNF724P at MOPED


See ZNF724P Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


ENSEMBL proteins: 
 ENSP00000413411   ENSP00000473253   ENSP00000471547  
Reactome Protein details: A8MTY0

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:
 IPR001909 Krueppel-associated_box
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry A8MTY0

ProtoNet protein and cluster: A8MTY0

UniProtKB/Swiss-Prot: ZN724_HUMAN, A8MTY0
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 16 C2H2-type zinc fingers
Similarity: Contains 1 KRAB domain


ZNF724P for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ZN724_HUMAN, A8MTY0
Function: May be involved in transcriptional regulation (By similarity)

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding ----
GO:0003677DNA binding IEA--
GO:0046872metal ion binding IEA--
     
ZNF724P for ontologies           About GeneDecksing


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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
ZN724_HUMAN, A8MTY0: Nucleus (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
cytosol2

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular ----
GO:0005634nucleus IEA--

ZNF724P for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ZNF724P About    
See pathways by source

SuperPathContained pathways About
1Gene Expression
Generic Transcription Pathway0.40
Gene Expression0.40

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


1 Reactome Pathway for ZNF724P
    Generic Transcription Pathway



ZNF724P for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF724P
Interactions:

    Search GeneGlobe Interaction Network for ZNF724P

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for ZNF724P (ENSP000004134114) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CBX5ENSP000002098754STRING: ENSP00000209875
About this table

Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated IEA--

ZNF724P for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
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Browse Tocris compounds for ZNF724P (ZN724)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000418100(uc021uru.1) ENST00000597537 ENST00000597037
miRNA
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2 AceView cDNA sequences:

BQ353521 BF087114 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZNF724P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACTAATCCCA
ZNF724P Expression
About this image

ZNF724P Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ZNF724P Protein Expression
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for ZNF724P gene from Selected species (see all 6)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 8)
Uncharacterized protein
(see all 8)
55(a)
47(a)
(see all 8)
many ↔ many
many ↔ many
(see all 8)
AAWZ02037240(11818-13836)
GL343434.1(292314-296903)
        Species with no ortholog for ZNF724P

ENSEMBL Gene Tree for ZNF724P (if available)
TreeFam Gene Tree for ZNF724P (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ZNF724P gene
ZNF852  ZNF4862  ZNF1952  ZNF922  ZNF1002  ZNF7322  ZNF6752  ZNF1382  
ZNF5062  ZNF662  ZNF2732  ZNF6952  ZNF6262  ZNF6802  ZNF4792  ZNF2532  
ZNF932  ZNF6822  ZNF4922  ZNF6762  ZNF6812  ZNF1412  ZNF7362  ZNF6792  
ZNF2572  ZNF2542  ZNF7372  ZNF982  ZNF7162  ZNF7142  ZNF4292  ZNF5192  
ZNF4302  ZNF7302  ZNF7082  ZNF1172  ZNF4312  ZNF902  ZNF7262  ZNF7282  
Selected SIMAP similar genes for ZNF724P using alignment to 3 protein entries:     ZN724_HUMAN (see all proteins) (see all similar genes):
MGC12518    ZNF98    ZNF273    ZNF506    ZNF430    ZNF730
ZNF100    ZNF429    ZNF90    ZNF257    ZNF738    ZNF818P
ZNF493    ZNF728    ZNF93    ZNF675    ZNF726    ZNF91

ZNF724P for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ZNF724P (see all 639)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1139127651,2
C,F--23406120(+) ATGTAG/TGGCTT 1 -- ds50012Minor allele frequency- T:0.07CSA WA 120
rs28856041,2
C,F,A--23406165(-) CAATCG/ATCAAC 1 -- ds500112Minor allele frequency- A:0.14NA WA CSA EA 375
rs1447914411,2
--23406303(+) CCAGTA/GTGAAT 1 -- ds50010--------
rs735595521,2
C,F--23406417(+) GTTGAG/AGACAC 1 -- ds50012Minor allele frequency- A:0.12WA 120
rs1176748141,2
C,F--23406418(+) TTGAGG/AACACA 1 -- ds50011Minor allele frequency- A:0.03EA 120
rs1831069281,2
C--23406528(+) CATTCC/TTTACA 1 -- ds50010--------
rs751648061,2
C,F--23406585(+) TTATGA/GAAGTC 1 -- ds50013Minor allele frequency- G:0.08CSA WA 121
rs778778081,2
F--23406738(+) TTTTCA/GTATTT 1 -- nc-transcript-variant1Minor allele frequency- G:0.03WA 118
rs1174732061,2
C,F--23406742(+) CATATT/GTTCTC 1 -- nc-transcript-variant2Minor allele frequency- G:0.07NA EU 714
rs1873927011,2
--23406744(+) TATTTC/TCTCAG 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for ZNF724P (23404401 - 23433192 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ZNF724P: --
Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing ZNF724P
DNA2.0 Custom Variant and Variant Library Synthesis for ZNF724P

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ZNF724P gene integrated from 10 sources:
(articles sorted by number of sources associating them with ZNF724P)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 440519 HGNC: 32460 AceView: LOC440519.1 Ensembl:ENSG00000196081 euGenes: HUgn440519
ECgene: ZNF724P H-InvDB: ZNF724P

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ZNF724P Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ZNF724P gene:
Search GeneIP for patents involving ZNF724P

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse SwitchGear 3'UTR luciferase reporter plasmids for ZNF724P
 Browse SwitchGear Promoter luciferase reporter plasmids for ZNF724P
 Search ThermoFisher Antibodies for ZNF724P
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF724P
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF724P
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZNF724P
 Search LSBio for Antibodies for ZNF724P
Customized transgenic rodents for:
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