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Aliases for ZNF717 Gene

Aliases for ZNF717 Gene

  • Zinc Finger Protein 717 2 3 5
  • Krueppel-Like Factor X17 3 4
  • Zinc Finger Protein 838 2 3
  • Kruppel-Like Zinc Finger Factor X17 3
  • ZNF838 3
  • X17 3

External Ids for ZNF717 Gene

Previous HGNC Symbols for ZNF717 Gene

  • ZNF838

Previous GeneCards Identifiers for ZNF717 Gene

  • GC03M075870
  • GC03U900858
  • GC03M075758

Summaries for ZNF717 Gene

GeneCards Summary for ZNF717 Gene

ZNF717 (Zinc Finger Protein 717) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding.

UniProtKB/Swiss-Prot for ZNF717 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF717 Gene

Genomics for ZNF717 Gene

Regulatory Elements for ZNF717 Gene

Enhancers for ZNF717 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF717 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF717 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF717 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF717 Gene

75,709,643 bp from pter
75,785,583 bp from pter
75,941 bases
Minus strand

Genomic View for ZNF717 Gene

Genes around ZNF717 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF717 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF717 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF717 Gene

Proteins for ZNF717 Gene

  • Protein details for ZNF717 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 717
    Protein Accession:

    Protein attributes for ZNF717 Gene

    904 amino acids
    Molecular mass:
    105251 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAK28319.1; Type=Frameshift; Positions=685; Evidence={ECO:0000305};

neXtProt entry for ZNF717 Gene

Proteomics data for ZNF717 Gene at MOPED

Post-translational modifications for ZNF717 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF717 Gene

Domains & Families for ZNF717 Gene

Gene Families for ZNF717 Gene

Protein Domains for ZNF717 Gene

Suggested Antigen Peptide Sequences for ZNF717 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 22 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 22 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF717: view

Function for ZNF717 Gene

Molecular function for ZNF717 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF717 Gene

GenomeRNAi human phenotypes for ZNF717:
genes like me logo Genes that share phenotypes with ZNF717: view

Animal Model Products

miRNA for ZNF717 Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF717 Gene

Localization for ZNF717 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF717 Gene

Subcellular locations from

Jensen Localization Image for ZNF717 Gene COMPARTMENTS Subcellular localization image for ZNF717 gene
Compartment Confidence
nucleus 5
plasma membrane 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF717 Gene

Pathways & Interactions for ZNF717 Gene

SuperPathways for ZNF717 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF717: view

Pathways by source for ZNF717 Gene

2 Reactome pathways for ZNF717 Gene

Interacting Proteins for ZNF717 Gene

Gene Ontology (GO) - Biological Process for ZNF717 Gene


No data available for SIGNOR curated interactions for ZNF717 Gene

Drugs & Compounds for ZNF717 Gene

No Compound Related Data Available

Transcripts for ZNF717 Gene

mRNA/cDNA for ZNF717 Gene

(19) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF717 Gene

Zinc finger protein 717:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF717 Gene

No ASD Table

Relevant External Links for ZNF717 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF717 Gene

mRNA expression in normal human tissues for ZNF717 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF717 Gene

This gene is overexpressed in Brain (43.3) and Platelet (25.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZNF717 Gene

SOURCE GeneReport for Unigene cluster for ZNF717 Gene Hs.556877

genes like me logo Genes that share expression patterns with ZNF717: view

Protein tissue co-expression partners for ZNF717 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF717 Gene

Orthologs for ZNF717 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF717 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Zfp39 35
  • 67.69 (n)
  • 54.43 (a)
Zfp39 16
Gm13212 36
  • 40 (a)
(Rattus norvegicus)
Mammalia Zfp39 35
  • 67.44 (n)
  • 50.93 (a)
(Bos Taurus)
Mammalia -- 36
  • 37 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 43 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
(Gallus gallus)
Aves -- 36
  • 36 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 54 (a)
(Danio rerio)
Actinopterygii si:ch211-209n20.58 36
  • 39 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
-- 36
  • 44 (a)
-- 36
  • 38 (a)
-- 36
  • 42 (a)
Species with no ortholog for ZNF717:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF717 Gene

Gene Tree for ZNF717 (if available)
Gene Tree for ZNF717 (if available)

Paralogs for ZNF717 Gene

(530) SIMAP similar genes for ZNF717 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF717: view

No data available for Paralogs for ZNF717 Gene

Variants for ZNF717 Gene

Sequence variations from dbSNP and Humsavar for ZNF717 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
VAR_059932 -
rs1052377 -- 75,730,313(-) CATCT(C/T)CTGAT intron-variant, utr-variant-3-prime
rs1866404 -- 75,718,319(+) GGAAG(A/T)CATTC intron-variant
rs460187 -- 75,735,379(+) GCCAC(A/G/T)ATACC intron-variant, downstream-variant-500B
rs1898697 -- 75,730,959(+) GAAGT(A/G)GCCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF717 Gene

Variant ID Type Subtype PubMed ID
esv2422315 CNV Deletion 17116639
esv614 CNV CNV 17122850
nsv529016 CNV Gain 19592680
esv26581 CNV Gain+Loss 19812545
dgv1469e1 CNV Complex 17122850
nsv876983 CNV Gain 21882294
nsv876984 CNV Gain 21882294
dgv1472e1 CNV Complex 17122850
dgv1473e1 CNV Complex 17122850
essv18298 CNV CNV 17122850
nsv428418 CNV Loss 18775914
nsv10283 CNV Gain+Loss 18304495
nsv876987 CNV Gain 21882294
dgv1474e1 CNV Complex 17122850
nsv821408 CNV Duplication 20802225
nsv822138 CNV Gain 20364138
nsv876988 CNV Loss 21882294
esv2436311 CNV Gain 19546169
dgv812n67 CNV Gain 20364138
nsv822140 CNV Loss 20364138
esv2671489 CNV Deletion 23128226
esv33470 CNV Loss 17666407
esv2725476 CNV Deletion 23290073
nsv471427 CNV Duplication 19718026
esv2725478 CNV Deletion 23290073
nsv513053 CNV Loss 21212237
esv2725479 CNV Deletion 23290073
esv9630 CNV Loss 19470904
esv2725480 CNV Deletion 23290073
esv2725481 CNV Deletion 23290073
esv2725482 CNV Deletion 23290073
esv2725483 CNV Deletion 23290073
esv2004829 CNV Deletion 18987734
esv2725484 CNV Deletion 23290073
esv2725486 CNV Deletion 23290073
esv2725487 CNV Deletion 23290073
esv2725488 CNV Deletion 23290073
dgv820e201 CNV Deletion 23290073
dgv821e201 CNV Deletion 23290073
dgv822e201 CNV Deletion 23290073
esv2725494 CNV Deletion 23290073
esv2725498 CNV Deletion 23290073
esv2661069 CNV Deletion 23128226
dgv5169n71 CNV Gain 21882294
esv2725500 CNV Deletion 23290073
esv2725501 CNV Deletion 23290073
esv2725502 CNV Deletion 23290073
esv1200496 CNV Insertion 17803354
esv2241639 CNV Deletion 18987734
esv2725503 CNV Deletion 23290073
esv2725504 CNV Deletion 23290073

Variation tolerance for ZNF717 Gene

Gene Damage Index Score: 2.86; 48.26% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF717 Gene

Disorders for ZNF717 Gene

Relevant External Links for ZNF717

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF717 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF717 Gene

Publications for ZNF717 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4 67
  2. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PMID: 21282530) Vandamme J. … Angrand P.O. (Mol. Cell. Proteomics 2011) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF717 Gene

Sources for ZNF717 Gene