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Aliases for ZNF714 Gene

Aliases for ZNF714 Gene

  • Zinc Finger Protein 714 2 3

External Ids for ZNF714 Gene

Previous GeneCards Identifiers for ZNF714 Gene

  • GC19P021052
  • GC19P021264
  • GC19P020755

Summaries for ZNF714 Gene

GeneCards Summary for ZNF714 Gene

ZNF714 (Zinc Finger Protein 714) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF714 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF714 Gene

Genomics for ZNF714 Gene

Regulatory Elements for ZNF714 Gene

Transcription factor binding sites by QIAGEN in the ZNF714 gene promoter:

Genomic Location for ZNF714 Gene

Start:
21,082,147 bp from pter
End:
21,125,270 bp from pter
Size:
43,124 bases
Orientation:
Plus strand

Genomic View for ZNF714 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF714 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF714 Gene

Proteins for ZNF714 Gene

  • Protein details for ZNF714 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N38-ZN714_HUMAN
    Recommended name:
    Zinc finger protein 714
    Protein Accession:
    Q96N38
    Secondary Accessions:
    • Q49AI1
    • Q86W65
    • Q8ND40

    Protein attributes for ZNF714 Gene

    Size:
    554 amino acids
    Molecular mass:
    63883 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH50468.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAD39077.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF714 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF714 Gene

Proteomics data for ZNF714 Gene at MOPED

Post-translational modifications for ZNF714 Gene

  • Ubiquitination at Lys397
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF714 Gene

No data available for DME Specific Peptides for ZNF714 Gene

Domains for ZNF714 Gene

Gene Families for ZNF714 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF714 Gene

Suggested Antigen Peptide Sequences for ZNF714 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96N38

UniProtKB/Swiss-Prot:

ZN714_HUMAN :
  • Q96N38
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF714: view

Function for ZNF714 Gene

Molecular function for ZNF714 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF714 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF714: view

miRNA for ZNF714 Gene

miRTarBase miRNAs that target ZNF714

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF714 Gene

Localization for ZNF714 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF714 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF714 Gene COMPARTMENTS Subcellular localization image for ZNF714 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF714 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF714: view

Pathways for ZNF714 Gene

SuperPathways for ZNF714 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF714: view

Pathways by source for ZNF714 Gene

2 Reactome pathways for ZNF714 Gene

Interacting Proteins for ZNF714 Gene

Selected Interacting proteins: Q96N38-ZN714_HUMAN for ZNF714 Gene via I2D

Symbol External ID(s) Details
LZTR1
PCBD1

Gene Ontology (GO) - Biological Process for ZNF714 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF714: view

Transcripts for ZNF714 Gene

mRNA/cDNA for ZNF714 Gene

Unigene Clusters for ZNF714 Gene

Zinc finger protein 714:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF714 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e · 5f · 5g · 5h
SP1:
SP2:
SP3: -
SP4: -
SP5: - -
SP6: -
SP7: - - -
SP8: - - - -

Relevant External Links for ZNF714 Gene

GeneLoc Exon Structure for
ZNF714
ECgene alternative splicing isoforms for
ZNF714

Expression for ZNF714 Gene

mRNA expression in normal human tissues for ZNF714 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF714 Gene

SOURCE GeneReport for Unigene cluster for ZNF714 Gene Hs.729186

genes like me logo Genes that share expressions with ZNF714: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF714 Gene

Orthologs for ZNF714 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF714 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF714 35
  • 99.58 (n)
  • 99.1 (a)
ZNF714 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 36 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp493 36
  • 55 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
Species with no ortholog for ZNF714:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF714 Gene

ENSEMBL:
Gene Tree for ZNF714 (if available)
TreeFam:
Gene Tree for ZNF714 (if available)

Paralogs for ZNF714 Gene

Selected SIMAP similar genes for ZNF714 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF714: view

Variants for ZNF714 Gene

Sequence variations from dbSNP and Humsavar for ZNF714 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs741674 -- 21,114,761(-) aaaca(A/C)agtga intron-variant
rs741675 -- 21,114,825(-) ctaga(C/T)agagc intron-variant
rs741676 -- 21,115,035(-) TACAC(A/G)AAACA intron-variant
rs1470021 -- 21,115,071(+) ATATT(A/G)GGAAT intron-variant
rs1470022 -- 21,115,339(+) TGCAT(G/T)TTTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF714 Gene

Variant ID Type Subtype PubMed ID
nsv458377 CNV Gain 19166990
nsv911412 CNV Loss 21882294
nsv911413 CNV Gain 21882294
esv2665276 CNV Deletion 23128226
esv2718324 CNV Deletion 23290073
dgv72e19 CNV Loss 19470904
esv5243 CNV Deletion 18987735
esv2660807 CNV Deletion 23128226
esv4924 CNV Complex 18987735
dgv551e201 CNV Deletion 23290073
esv2718325 CNV Deletion 23290073

Relevant External Links for ZNF714 Gene

HapMap Linkage Disequilibrium report
ZNF714

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF714 Gene

Disorders for ZNF714 Gene

(1) University of Copenhagen DISEASES for ZNF714 Gene

genes like me logo Genes that share disorders with ZNF714: view

No data available for UniProtKB/Swiss-Prot for ZNF714 Gene

Publications for ZNF714 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for ZNF714 Gene

Sources for ZNF714 Gene

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