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Aliases for ZNF713 Gene

Aliases for ZNF713 Gene

  • Zinc Finger Protein 713 2 3

External Ids for ZNF713 Gene

Previous GeneCards Identifiers for ZNF713 Gene

  • GC07P055755
  • GC07P055947
  • GC07P055794

Summaries for ZNF713 Gene

Entrez Gene Summary for ZNF713 Gene

  • The protein encoded by this gene contains C2H2 zinc finger domains. In some individuals a CGG-repeat expansion mutation has been identified in the first intron of this gene. This mutation is thought to effect the expression of this gene and it has been proposed that it may be associated with Autistic Spectrum Disorder. [provided by RefSeq, Feb 2015]

GeneCards Summary for ZNF713 Gene

ZNF713 (Zinc Finger Protein 713) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZFP69.

UniProtKB/Swiss-Prot for ZNF713 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF713 Gene

Genomics for ZNF713 Gene

Regulatory Elements for ZNF713 Gene

Transcription factor binding sites by QIAGEN in the ZNF713 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF713 Gene

Start:
55,887,476 bp from pter
End:
55,942,225 bp from pter
Size:
54,750 bases
Orientation:
Plus strand

Genomic View for ZNF713 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF713 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF713 Gene

Proteins for ZNF713 Gene

  • Protein details for ZNF713 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N859-ZN713_HUMAN
    Recommended name:
    Zinc finger protein 713
    Protein Accession:
    Q8N859
    Secondary Accessions:

    Protein attributes for ZNF713 Gene

    Size:
    430 amino acids
    Molecular mass:
    50172 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF713 Gene

Proteomics data for ZNF713 Gene at MOPED

Post-translational modifications for ZNF713 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF713 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF713 Gene

Domains for ZNF713 Gene

Gene Families for ZNF713 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF713 Gene

Suggested Antigen Peptide Sequences for ZNF713 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N859

UniProtKB/Swiss-Prot:

ZN713_HUMAN :
  • Q8N859
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF713: view

Function for ZNF713 Gene

Molecular function for ZNF713 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF713 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF713: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF713 Gene

Localization for ZNF713 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF713 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF713 Gene COMPARTMENTS Subcellular localization image for ZNF713 gene
Compartment Confidence
mitochondrion 5
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF713 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF713: view

Pathways for ZNF713 Gene

SuperPathways for ZNF713 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF713: view

Pathways by source for ZNF713 Gene

2 Reactome pathways for ZNF713 Gene

Interacting Proteins for ZNF713 Gene

Gene Ontology (GO) - Biological Process for ZNF713 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF713: view

Transcripts for ZNF713 Gene

mRNA/cDNA for ZNF713 Gene

Unigene Clusters for ZNF713 Gene

Zinc finger protein 713:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF713

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF713
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF713 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5
SP1:
SP2: -

Relevant External Links for ZNF713 Gene

GeneLoc Exon Structure for
ZNF713
ECgene alternative splicing isoforms for
ZNF713

Expression for ZNF713 Gene

mRNA expression in normal human tissues for ZNF713 Gene

SOURCE GeneReport for Unigene cluster for ZNF713 Gene Hs.660834

genes like me logo Genes that share expressions with ZNF713: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF713 Gene

Orthologs for ZNF713 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF713 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF713 35
  • 99.22 (n)
  • 99.07 (a)
ZNF713 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF713 35
  • 88.51 (n)
  • 87.86 (a)
ZNF713 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 35 (a)
ManyToMany
ZNF713 35
  • 88.45 (n)
  • 84.07 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 39 (a)
OneToMany
Species with no ortholog for ZNF713:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF713 Gene

ENSEMBL:
Gene Tree for ZNF713 (if available)
TreeFam:
Gene Tree for ZNF713 (if available)

Paralogs for ZNF713 Gene

Paralogs for ZNF713 Gene

Selected SIMAP similar genes for ZNF713 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF713: view

Variants for ZNF713 Gene

Sequence variations from dbSNP and Humsavar for ZNF713 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1394721 -- 55,912,480(-) TGTTC(A/G)GGAGT upstream-variant-2KB
rs1472767 -- 55,932,545(-) TATTA(A/G)Atttt intron-variant
rs1967230 -- 55,932,606(-) cgccc(A/G)gctGT intron-variant
rs2062921 -- 55,935,816(-) cacca(A/C)actcg intron-variant
rs2135116 -- 55,923,451(-) TTCCA(C/T)TGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF713 Gene

Variant ID Type Subtype PubMed ID
esv2734425 CNV Deletion 23290073
esv28230 CNV Gain+Loss 19812545
esv2734447 CNV Deletion 23290073
dgv1201e199 CNV Deletion 23128226
nsv888064 CNV Gain 21882294
esv2734448 CNV Deletion 23290073
nsv365792 CNV Loss 16902084
nsv824110 CNV Loss 20364138
esv2674331 CNV Deletion 23128226

Relevant External Links for ZNF713 Gene

HapMap Linkage Disequilibrium report
ZNF713
Human Gene Mutation Database (HGMD)
ZNF713

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF713 Gene

Disorders for ZNF713 Gene

No disorders were found for ZNF713 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF713 Gene

Publications for ZNF713 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  3. A CGG-repeat expansion mutation in ZNF713 causes FRA7A: association with autistic spectrum disorder in two families. (PMID: 25196122) Metsu S. … FitzPatrick D.R. (Hum. Mutat. 2014) 3
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF713 Gene

Sources for ZNF713 Gene

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