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ZNF711 Gene

protein-coding   GIFtS: 59
GCID: GC0XP084498

Zinc Finger Protein 711

(Previous names: zinc finger protein 6 (CMPX1), zinc finger protein 6)
(Previous symbol: ZNF6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 7111 2     ZNF42
ZNF61 2 3 5     ZNF52
CMPX12 3 5     Zfp7112
Zinc Finger Protein 6 (CMPX1)1 2     dJ75N13.12
Zinc Finger Protein 61 3     DJ75N13.1 (Znf6-Like)2
MRX972 5     

External Ids:    HGNC: 131281   Entrez Gene: 75522   Ensembl: ENSG000001471807   OMIM: 3149905   UniProtKB: Q9Y4623   

Export aliases for ZNF711 gene to outside databases

Previous GC identifers: GC0XP084385 GC0XP078072


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZNF711 Gene:
This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which
acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated
with mental retardation. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZNF711 Gene:
ZNF711 (zinc finger protein 711) is a protein-coding gene. Diseases associated with ZNF711 include znf711-related x-linked mental retardation, and mental retardation, x-linked 97. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is ZNF639.

UniProtKB/Swiss-Prot: ZN711_HUMAN, Q9Y462
Function: Transcription regulator required for brain development. Probably acts as a transcription factor that
binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of
genes involved in neuron development, such as KDM5C




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF711 gene promoter:
         E2F-4   E2F-3a   E2F-5   RFX1   GATA-3   E2F-2   GATA-2   GATA-1   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF711 promoter sequence
   Search Chromatin IP Primers for ZNF711

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF711


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq21.1   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

ZNF711 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF711 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP084498:  view genomic region     (about GC identifiers)

Start:
84,498,997 bp from pter      End:
84,528,368 bp from pter
Size:
29,372 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZN711_HUMAN, Q9Y462 (See protein sequence)
Recommended Name: Zinc finger protein 711  
Size: 761 amino acids; 86245 Da
Subunit: Interacts with PHF8
Sequence caution: Sequence=BAG61766.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAA39837.2; Type=Frameshift; Positions=Several; Sequence=CAA39837.2; Type=Miscellaneous discrepancy;
Note=Chimera;
Secondary accessions: B4DSV4 Q6NX42 Q9Y4J6
Alternative splicing: 3 isoforms:  Q9Y462-1   Q9Y462-2   Q9Y462-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF711: NX_Q9Y462

Explore proteomics data for ZNF711 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys224, Lys289
  • Modification sites at PhosphoSitePlus

  • See ZNF711 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_068838.3  
    ENSEMBL proteins: 
     ENSP00000362260   ENSP00000276123   ENSP00000353922   ENSP00000378798   ENSP00000442071  
    Reactome Protein details: Q9Y462

    ZNF711 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR006794 Transcrp_activ_Zfx/Zfy-dom
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9Y462

    ProtoNet protein and cluster: Q9Y462

    1 Blocks protein domain: IPB006794 Zfx / Zfy transcription activation region

    UniProtKB/Swiss-Prot: ZN711_HUMAN, Q9Y462
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 12 C2H2-type zinc fingers


    ZNF711 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN711_HUMAN, Q9Y462
    Function: Transcription regulator required for brain development. Probably acts as a transcription factor that
    binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of
    genes involved in neuron development, such as KDM5C

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0005515protein binding IPI--
    GO:0043565sequence-specific DNA binding IDA--
    GO:0046872metal ion binding IEA--
         
    ZNF711 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ZNF711:
     Cell division defect  Decreased POU5F1-GFP protein e  Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF711
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF711
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF711

    Transcription Factor Targeting: 
    Targeting motifs: HOMER Transcription Factor Regulatory Elements motif viewer 
                                          Consensus sequence:  AGGCCTAG 

    miRNA
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    miRTarBase miRNAs that target ZNF711:
    hsa-mir-218-5p (MIRT046981), hsa-mir-151a-3p (MIRT043601), hsa-mir-18a-5p (MIRT031317), hsa-mir-615-3p (MIRT040430), hsa-mir-19b-3p (MIRT031177), hsa-mir-335-5p (MIRT017955)

    Block miRNA regulation of human, mouse, rat ZNF711 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF711 (see all 30):
    hsa-miR-3149 hsa-miR-30c hsa-miR-217 hsa-miR-448 hsa-miR-3607-3p hsa-miR-429 hsa-miR-301a hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidZNF711 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF711

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF711

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF711


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN711_HUMAN, Q9Y462: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    ZNF711 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF711 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF711
        Generic Transcription Pathway



    ZNF711 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF711
    Interactions:

        Search GeneGlobe Interaction Network for ZNF711

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZNF711 (Q9Y4623 ENSP000002761234) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PHF8Q9UPP13, ENSP000003388684I2D: score=1 STRING: ENSP00000338868
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0045893positive regulation of transcription, DNA-templated IMP--

    ZNF711 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF711 (ZN711)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZNF711 gene: 
    NM_021998.4  

    Unigene Cluster for ZNF711:

    Zinc finger protein 711
    Hs.326801  [show with all ESTs]
    Unigene Representative Sequence: BX648117
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373165(uc011mqy.1 uc004eeo.3) ENST00000276123 ENST00000360700(uc004eep.3 uc004eeq.3)
    ENST00000395402 ENST00000542798
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZNF711 (see all 30):
    hsa-miR-3149 hsa-miR-30c hsa-miR-217 hsa-miR-448 hsa-miR-3607-3p hsa-miR-429 hsa-miR-301a hsa-miR-513c
    SwitchGear 3'UTR luciferase reporter plasmidZNF711 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF711
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF711 (NM_021998)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF711
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF711
    Primer
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    OriGene qPCR primer pairs and template standards for ZNF711
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF711
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF711
      QuantiFast Probe-based Assays in human, mouse, rat ZNF711

    Additional mRNA sequence: 

    AK294953.1 AK299604.1 AK299933.1 AK308097.1 AY726603.1 BC006349.2 BC067294.1 BX648117.1 

    7 DOTS entries:

    DT.100672885  DT.100810979  DT.102825354  DT.75120096  DT.97796447  DT.121307078  DT.121307084 

    Selected AceView cDNA sequences (see all 54):

    AI453159 CB053788 BM979874 BX648117 BM724321 BI524105 T16534 AA928817 
    BP379715 BU741599 BC006349 BC067294 NM_021998 BE675513 R19445 CB962230 
    BM975110 BF203844 BM971168 AL042650 R44692 BI598126 AU137084 AA897714 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF711 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13
    SP1:                                                                                                  -                                 
    SP2:                                                                                                                                    
    SP3:                                                                                                                                    
    SP4:                                                                                                  -                                 
    SP5:                    -     -     -                                                                                                   


    ECgene alternative splicing isoforms for ZNF711

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF711 expression in normal human tissues (normalized intensities)      ZNF711 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTATATTGTG
    ZNF711 Expression
    About this image


    ZNF711 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Epithelial Cells
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Gonad
             XX Germ Cells Ovigerous Cord
     
     Eye (Sensory Organs)
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Yolk Sac (Extraembryonic Tissues)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
    ZNF711 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF711 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.326801

    UniProtKB/Swiss-Prot: ZN711_HUMAN, Q9Y462
    Tissue specificity: Expressed in neural tissues

        Custom PCR Arrays for ZNF711
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF711

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF711 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp7111 , 5 zinc finger protein 7111, 5 92.29(n)1
    96.32(a)1
      X (48.76 cM)5
    2455951  NM_177747.31  NP_808415.21 
     1126005265 
    chicken
    (Gallus gallus)
    Aves ZNF7111 zinc finger protein 711 81.37(n)
    87.19(a)
      422269  XM_420253.4  XP_420253.4 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF7116
    zinc finger protein 711
    81(a)
    1 ↔ 1
    GL343202.1(1113841-1128927)
    zebrafish
    (Danio rerio)
    Actinopterygii znf7111 zinc finger protein 711 67.94(n)
    73.53(a)
      562505  NM_001105523.1  NP_001098993.1 


    ENSEMBL Gene Tree for ZNF711 (if available)
    TreeFam Gene Tree for ZNF711 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF711 gene
    ZNF6392  ZFY2  ZFX2  
    Selected SIMAP similar genes for ZNF711 using alignment to 4 protein entries:     ZN711_HUMAN (see all proteins) (see all similar genes):
    ZFY    ZFX    ZNF55    kr-znf3    HZF16    KLF4
    ZBTB17    ZNF    ZNF672    A-328A3.4    ZFS-2    ZFS-5
    ZNF500    HZF36    ZNF410    ZSCAN21    DKFZp686N0199    KLF1

    ZNF711 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF711 (see all 423)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1994222401,2
    Cpathogenic184500100(+) ATATGA/TGAACC 2 R * stg10--------
    rs20668961,2
    C,F--84471222(+) CTGAAA/C/GAAGGT 1 -- us2k11CSA 1
    rs1415178401,2
    C--84471287(+) CTCAGG/TATATT 1 -- us2k10--------
    rs1812790811,2
    --84471979(+) TATCTA/GTCTAT 1 -- us2k10--------
    rs1854830341,2
    --84472008(+) TAGTAA/GTAACT 1 -- us2k10--------
    rs1898747981,2
    C--84472044(+) AATTAC/TATCTC 1 -- us2k10--------
    rs21066661,2
    C,F,A--84472100(+) CAGAGC/GAGAGT 1 -- us2k13Minor allele frequency- G:0.33NA WA 6
    rs10066291,2
    C,F,A,H--84472130(+) tagccC/Ttcaaa 1 -- us2k113Minor allele frequency- T:0.13NS EA NA WA 1688
    rs1442257231,2
    --84472210(+) TTTGCC/TGACTC 1 -- us2k10--------
    rs1823458761,2
    --84472596(+) AGCTGA/TAAGTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF711 (84498997 - 84528368 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF711:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2466752CNV Deletion19546169
    esv2740275CNV Deletion23290073

    Human Gene Mutation Database (HGMD): ZNF711
    Locus Specific Mutation Databases (LSDB): ZNF711

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF711
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 314990   
    OMIM disorders: 300803  
    UniProtKB/Swiss-Prot: ZN711_HUMAN, Q9Y462
  • Mental retardation, X-linked, ZNF711-related (MRXZ) [MIM:300803]: A disorder characterized by
    significantly below average general intellectual functioning associated with impairments in adaptive behavior and
    manifested during the developmental period. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • 13 diseases for ZNF711:    About MalaCards
    znf711-related x-linked mental retardation    mental retardation, x-linked 97    allan-herndon-dudley syndrome    mental retardation, x-linked 17/31, microduplication
    autism spectrum disorder    mental retardation    intellectual disability    mental retardation, x-linked
    multiple myeloma    myeloma    retinitis    neuronitis
    hepatitis

    1 disease from the University of Copenhagen DISEASES database for ZNF711:
    Allan-Herndon-Dudley syndrome

    ZNF711 for disorders           About GeneDecksing


    Export disorders for ZNF711 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF711 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with ZNF711)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PubMed id 19377476)1, 2, 3 Tarpey P.S.... Stratton M.R. (Nat. Genet. 2009)
    2. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. (PubMed id 20346720)1, 2 Kleine-Kohlbrecher D....Helin K. (Mol. Cell 2010)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. An X linked zinc finger gene mapping to Xq21.1-q21.3 closely related to ZFX and ZFY. Possible origins from a common ancestral gene. (PubMed id 1923752)1, 2 Lloyd S.L....Affara N.A. (Nucleic Acids Res. 1991)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Fine mapping of Xq11.1-q21.33 and mutation screening of RPS6KA6, ZNF711, ACSL4, DLG3, and IL1RAPL2 for autism spectrum disorders (ASD). (PubMed id 21384559)1 KantojAorvi K....JAorvelAo I. (Autism Res 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7552 HGNC: 13128 AceView: ZNF6 Ensembl:ENSG00000147180 euGenes: HUgn7552
    ECgene: ZNF711 H-InvDB: ZNF711

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZNF711 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ZNF711 gene:
    Search GeneIP for patents involving ZNF711

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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