ZNF710 Gene
protein-coding GIFtS: 44
GCID: GC15P090544
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zinc finger protein 710
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Aliases
for ZNF710 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 7101 2 | | DKFZp547K11131 | | FLJ003061 | | FLJ373931 |
Export aliases for ZNF710 gene to outside databasesPrevious GC identifers: GC15P088346 GC15P066721 |
Summaries
for ZNF710 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN710_HUMAN, Q8N1W2Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF710 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF710 gene promoter:
HFH-3 AML1a Tal-1 ATF-2 GATA-1 E47 FOXI1 HEN1 CRE-BP1 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF710
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF710 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.1 Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26.1ZNF710 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P090544: view genomic region
(about GC identifiers)
Start:
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90,544,624 bp from pter |
End:
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90,625,438 bp from pter |
Size:
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80,815 bases |
Orientation:
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plus strand |
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Proteins
for ZNF710 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN710_HUMAN, Q8N1W2 (See
protein sequence)Recommended Name: Zinc finger protein 710 Size: 664 amino acids; 74461 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A0AVS3 Q6ZMK9 Q8NDU0Explore the universe of human proteins at neXtProt for ZNF710: NX_Q8N1W2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N1W2
ZNF710 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940928.2
ENSEMBL proteins: ENSP00000268154 ENSP00000452993 ENSP00000453404 ENSP00000453147 Reactome Protein details: Q8N1W2
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF710 for ontologies About GeneDecksing
ZNF710 Antibody Products:
Assay Products for ZNF710: |
Protein
Domains /
Families
for ZNF710 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF710 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N1W2ProtoNet protein and cluster: Q8N1W2 UniProtKB/Swiss-Prot: ZN710_HUMAN, Q8N1W2Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingers |
Function
for ZNF710 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN710_HUMAN, Q8N1W2Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF710 (NM_198526) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF710 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF710 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF710 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF710 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF710 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF710
ZNF710 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF710
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF710 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF710 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF710
Search CenterWatch for drugs/clinical trials and news about ZNF710 / ZN710
|
Transcripts
for ZNF710 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF710 gene: NM_198526.2 Unigene Cluster for ZNF710: Zinc finger protein 710 Hs.459311 [show with all ESTs]Unigene Representative Sequence: NM_1985265 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000268154(uc002bov.2) ENST00000559419 ENST00000558883 ENST00000559360
ENST00000560908
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF710 (NM_198526) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF710 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF710 |
Additional cDNA sequence: AK094712.1 AK160373.1 AL831826.1 BC020301.1 BC126476.1 BC130541.1 5 DOTS entries: DT.121027175 DT.100027620 DT.97802552 DT.439227 DT.91766554 24/184 AceView cDNA sequences (see all 184): BG059753 F01734 BM803864 AA905524 AI417408 AI569675 BQ614288 AI092856 T33651 AI378912 BE249848 NM_198526 AI493670 AL831826 AI962492 BQ941527 AI796844 AA907113 BE856772 AA976277 AW015547 AK160373 AK094712 AA417562
GeneLoc Exon Structure
|
Expression
for ZNF710 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF710 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGCAGGGCA
About this image
See ZNF710 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF710
SOURCE GeneReport for Unigene cluster: Hs.459311
SABiosciences Custom PCR Arrays for ZNF710
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF710
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF710 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF710 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF710 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF710 |
Orthologs
for ZNF710 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF710 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for ZNF710 (if available)
TreeFam Gene Tree for ZNF710 (if available) |
Paralogs
for ZNF710 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF710 gene
- ZNF3662
18/328 SIMAP similar genes for ZNF710 using alignment to 4 protein entries: ZN710_HUMAN (see all proteins)
(see all similar genes):ZNF366 ZNF55 GFI1 ZNF596 kr-znf3 A-328A3.4
ZBTB44 ZFP41 ZNF226 ZNF72 HKR1 ZFS-1
ZSCAN21 ZSCAN22 ZNF ZFP112 HZF16 ZFS-6
ZNF710 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF710 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF710 (90544624 - 90625438 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ZNF710
5 CNVs: 77066 8803 3976 3094 5804 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF710 |
|
Disorders
/ Diseases
for ZNF710 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF710 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF710 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF710) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for ZNF710 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZNF710 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF710 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF710 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF710 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF710 gene:
Search GeneIP for patents involving ZNF710
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF710 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF710 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF710 | | | OriGene Protein Over-expression Lysate for ZNF710 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZNF710 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF710 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF710 | | OriGene Custom Protein Services for ZNF710 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF710 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF710 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF710 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF710 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF710 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF710 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF710 |
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 | | | ZNF710 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF710 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF710 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF710 |
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