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Aliases for ZNF710 Gene

Aliases for ZNF710 Gene

  • Zinc Finger Protein 710 2 3 5

External Ids for ZNF710 Gene

Previous GeneCards Identifiers for ZNF710 Gene

  • GC15P088346
  • GC15P090544
  • GC15P066721

Summaries for ZNF710 Gene

GeneCards Summary for ZNF710 Gene

ZNF710 (Zinc Finger Protein 710) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription cofactor activity. An important paralog of this gene is ZNF366.

UniProtKB/Swiss-Prot for ZNF710 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF710 Gene

Genomics for ZNF710 Gene

Regulatory Elements for ZNF710 Gene

Enhancers for ZNF710 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF710 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF710 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF710 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF710 Gene

Chromosome:
15
Start:
89,999,046 bp from pter
End:
90,082,206 bp from pter
Size:
83,161 bases
Orientation:
Plus strand

Genomic View for ZNF710 Gene

Genes around ZNF710 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF710 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF710 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF710 Gene

Proteins for ZNF710 Gene

  • Protein details for ZNF710 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N1W2-ZN710_HUMAN
    Recommended name:
    Zinc finger protein 710
    Protein Accession:
    Q8N1W2
    Secondary Accessions:
    • A0AVS3
    • Q6ZMK9
    • Q8NDU0

    Protein attributes for ZNF710 Gene

    Size:
    664 amino acids
    Molecular mass:
    74461 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF710 Gene

Proteomics data for ZNF710 Gene at MOPED

Post-translational modifications for ZNF710 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF710 Gene

No data available for DME Specific Peptides for ZNF710 Gene

Domains & Families for ZNF710 Gene

Gene Families for ZNF710 Gene

Protein Domains for ZNF710 Gene

Suggested Antigen Peptide Sequences for ZNF710 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N1W2

UniProtKB/Swiss-Prot:

ZN710_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF710: view

Function for ZNF710 Gene

Molecular function for ZNF710 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF710 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF710: view

Phenotypes for ZNF710 Gene

genes like me logo Genes that share phenotypes with ZNF710: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF710 Gene

Localization for ZNF710 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF710 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF710 Gene COMPARTMENTS Subcellular localization image for ZNF710 gene
Compartment Confidence
nucleus 5
cytosol 3
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for ZNF710 Gene

Pathways & Interactions for ZNF710 Gene

SuperPathways for ZNF710 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF710: view

Pathways by source for ZNF710 Gene

2 Reactome pathways for ZNF710 Gene

Interacting Proteins for ZNF710 Gene

Gene Ontology (GO) - Biological Process for ZNF710 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF710: view

No data available for SIGNOR curated interactions for ZNF710 Gene

Drugs & Compounds for ZNF710 Gene

No Compound Related Data Available

Transcripts for ZNF710 Gene

Unigene Clusters for ZNF710 Gene

Zinc finger protein 710:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF710 Gene

No ASD Table

Relevant External Links for ZNF710 Gene

GeneLoc Exon Structure for
ZNF710
ECgene alternative splicing isoforms for
ZNF710

Expression for ZNF710 Gene

mRNA expression in normal human tissues for ZNF710 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF710 Gene

This gene is overexpressed in Pancreas (x4.2).

Protein differential expression in normal tissues from HIPED for ZNF710 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF710 Gene



SOURCE GeneReport for Unigene cluster for ZNF710 Gene Hs.459311

genes like me logo Genes that share expression patterns with ZNF710: view

Protein tissue co-expression partners for ZNF710 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF710 Gene

Orthologs for ZNF710 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF710 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF710 35
  • 90.91 (n)
  • 94.58 (a)
ZNF710 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF710 35
  • 92.01 (n)
  • 95.32 (a)
ZNF710 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp710 35
  • 88.91 (n)
  • 94.58 (a)
Zfp710 16
Zfp710 36
  • 94 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF710 35
  • 99.4 (n)
  • 99.55 (a)
ZNF710 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp710 35
  • 89.04 (n)
  • 94.9 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF710 36
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF710 35
  • 80.3 (n)
  • 78.43 (a)
ZNF710 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF710 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf710 35
  • 68.54 (n)
  • 72.15 (a)
zebrafish
(Danio rerio)
Actinopterygii wufi04b07 35
znf710a 35
  • 71.03 (n)
  • 73.39 (a)
ZNF710 (1 of 2) 36
  • 48 (a)
OneToMany
znf710a 36
  • 49 (a)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9921 35
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PZF1 36
  • 22 (a)
OneToMany
PZF1 38
Species with no ortholog for ZNF710:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF710 Gene

ENSEMBL:
Gene Tree for ZNF710 (if available)
TreeFam:
Gene Tree for ZNF710 (if available)

Paralogs for ZNF710 Gene

Paralogs for ZNF710 Gene

(303) SIMAP similar genes for ZNF710 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF710: view

Variants for ZNF710 Gene

Sequence variations from dbSNP and Humsavar for ZNF710 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs4932154 -- 90,031,028(+) aaaaa(A/G)aaaaa intron-variant
rs4932155 -- 90,031,359(+) ATGGA(A/G)ACGAA intron-variant
rs4932156 -- 90,074,000(+) AAAAA(A/C)AAAAA intron-variant
rs4932271 -- 90,021,392(+) CCTGT(A/G)AAATG intron-variant
rs4932272 -- 90,021,482(+) GTGCT(A/G)TGAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF710 Gene

Variant ID Type Subtype PubMed ID
esv997696 CNV Deletion 20482838
dgv776e1 CNV Complex 17122850
nsv827430 CNV Loss 20364138
nsv94745 CNV Loss 16902084
nsv904486 CNV Gain 21882294
dgv112e55 CNV Gain 17911159
dgv777e1 CNV Complex 17122850

Variation tolerance for ZNF710 Gene

Residual Variation Intolerance Score: 48.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.45; 43.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF710 Gene

HapMap Linkage Disequilibrium report
ZNF710

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF710 Gene

Disorders for ZNF710 Gene

Relevant External Links for ZNF710

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF710

No disorders were found for ZNF710 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF710 Gene

Publications for ZNF710 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ZNF710 Gene

Sources for ZNF710 Gene

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