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Aliases for ZNF71 Gene

Aliases for ZNF71 Gene

  • Zinc Finger Protein 71 2 3 4
  • EZFIT 3 4
  • Endothelial Zinc Finger Protein Induced By Tumor Necrosis Factor Alpha 3
  • Kruppel-Related Zinc Finger Protein 3
  • Zinc Finger Protein 71 (Cos26) 2

External Ids for ZNF71 Gene

Previous GeneCards Identifiers for ZNF71 Gene

  • GC22U990056
  • GC19P057560
  • GC19P061593
  • GC19P061617
  • GC19P061608
  • GC19P061798
  • GC19P057108
  • GC19P053416

Summaries for ZNF71 Gene

GeneCards Summary for ZNF71 Gene

ZNF71 (Zinc Finger Protein 71) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF10.

UniProtKB/Swiss-Prot for ZNF71 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF71 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF71 Gene

Genomics for ZNF71 Gene

Regulatory Elements for ZNF71 Gene

Genomic Location for ZNF71 Gene

Start:
56,595,264 bp from pter
End:
56,626,481 bp from pter
Size:
31,218 bases
Orientation:
Plus strand

Genomic View for ZNF71 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF71 Gene

Proteins for ZNF71 Gene

  • Protein details for ZNF71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQZ8-ZNF71_HUMAN
    Recommended name:
    Endothelial zinc finger protein induced by tumor necrosis factor alpha
    Protein Accession:
    Q9NQZ8
    Secondary Accessions:
    • Q15919
    • Q9UC09
    • Q9UQD3

    Protein attributes for ZNF71 Gene

    Size:
    489 amino acids
    Molecular mass:
    54498 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD23608.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF71 Gene

Proteomics data for ZNF71 Gene at MOPED

Post-translational modifications for ZNF71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF71 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF71 Gene

Domains for ZNF71 Gene

Gene Families for ZNF71 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF71 Gene

Suggested Antigen Peptide Sequences for ZNF71 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NQZ8

UniProtKB/Swiss-Prot:

ZNF71_HUMAN :
  • Q9NQZ8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF71: view

Function for ZNF71 Gene

Molecular function for ZNF71 Gene

GENATLAS Biochemistry: zinc finger protein 71 (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation
UniProtKB/Swiss-Prot Induction: By TNF

Gene Ontology (GO) - Molecular Function for ZNF71 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF71: view

miRNA for ZNF71 Gene

miRTarBase miRNAs that target ZNF71

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF71 Gene

Localization for ZNF71 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF71 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF71 Gene COMPARTMENTS Subcellular localization image for ZNF71 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF71 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF71: view

Pathways for ZNF71 Gene

SuperPathways for ZNF71 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF71: view

Pathways by source for ZNF71 Gene

2 Reactome pathways for ZNF71 Gene

Gene Ontology (GO) - Biological Process for ZNF71 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF71: view

Compounds for ZNF71 Gene

(1) Novoseek inferred chemical compound relationships for ZNF71 Gene

Compound -log(P) Hits PubMed IDs
zinc 61.8 9
genes like me logo Genes that share compounds with ZNF71: view

Transcripts for ZNF71 Gene

mRNA/cDNA for ZNF71 Gene

Unigene Clusters for ZNF71 Gene

Zinc finger protein 71:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF71 Gene

No ASD Table

Relevant External Links for ZNF71 Gene

GeneLoc Exon Structure for
ZNF71
ECgene alternative splicing isoforms for
ZNF71

Expression for ZNF71 Gene

mRNA expression in normal human tissues for ZNF71 Gene

SOURCE GeneReport for Unigene cluster for ZNF71 Gene Hs.301431

mRNA Expression by UniProt/SwissProt for ZNF71 Gene

Q9NQZ8-ZNF71_HUMAN
Tissue specificity: Highly expressed in placenta, followed by brain, testis, pancreas, heart, small intestine, muscle, uterus, prostate and peripheral blood leukocytes. Not detected in liver, lung, colon, stomach, salivary and thyroid gland
genes like me logo Genes that share expressions with ZNF71: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for ZNF71 Gene

Orthologs for ZNF71 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF71 35
  • 99.59 (n)
  • 99.18 (a)
ZNF71 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
ManyToMany
ZNF71 35
  • 83.09 (n)
  • 82.27 (a)
dog
(Canis familiaris)
Mammalia ZNF71 35
  • 79.91 (n)
  • 82.72 (a)
ZNF71 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 48 (a)
OneToMany
ZNF71 35
  • 62.39 (n)
  • 51.9 (a)
Species with no ortholog for ZNF71:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF71 Gene

ENSEMBL:
Gene Tree for ZNF71 (if available)
TreeFam:
Gene Tree for ZNF71 (if available)

Paralogs for ZNF71 Gene

Selected SIMAP similar genes for ZNF71 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF71: view

Variants for ZNF71 Gene

Sequence variations from dbSNP and Humsavar for ZNF71 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs714082 -- 56,613,760(+) CTCCA(C/T)GCCTC intron-variant
rs887954 -- 56,608,988(+) tgtta(C/T)ggttg intron-variant
rs887955 -- 56,609,001(+) caaag(A/G)cttgc intron-variant
rs929627 -- 56,614,851(+) aagag(A/T)ttcct intron-variant
rs1024785 -- 56,614,399(+) TTGGG(A/T)CAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF71 Gene

Variant ID Type Subtype PubMed ID
nsv912518 CNV Gain 21882294
esv2719039 CNV Deletion 23290073
esv8168 CNV Loss 19470904
esv2719041 CNV Deletion 23290073
nsv912520 CNV Loss 21882294
nsv912521 CNV Gain 21882294

Relevant External Links for ZNF71 Gene

HapMap Linkage Disequilibrium report
ZNF71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF71 Gene

Disorders for ZNF71 Gene

(2) Novoseek inferred disease relationships for ZNF71 Gene

Disease -log(P) Hits PubMed IDs
necrosis 4.77 1
tumors 0 1

Relevant External Links for ZNF71

Genetic Association Database (GAD)
ZNF71
Human Genome Epidemiology (HuGE) Navigator
ZNF71
genes like me logo Genes that share disorders with ZNF71: view

No data available for UniProtKB/Swiss-Prot for ZNF71 Gene

Publications for ZNF71 Gene

  1. A novel zinc finger protein mRNA in human umbilical vein endothelial cells is profoundly induced by tumor necrosis factor alpha. (PMID: 11426589) Mataki C. … Kodama T. (J. Atheroscler. Thromb. 2000) 3 4 23
  2. Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2). (PMID: 1639391) Aubry M. … Rouleau G.A. (Genomics 1992) 2 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C. … Hunter D.J. (Hum. Genet. 2010) 3 48

Products for ZNF71 Gene

Sources for ZNF71 Gene

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