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Aliases for ZNF709 Gene

Aliases for ZNF709 Gene

  • Zinc Finger Protein 709 2 3

External Ids for ZNF709 Gene

Previous GeneCards Identifiers for ZNF709 Gene

  • GC19M012434
  • GC19M012571
  • GC19M012145

Summaries for ZNF709 Gene

GeneCards Summary for ZNF709 Gene

ZNF709 (Zinc Finger Protein 709) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF788.

UniProtKB/Swiss-Prot for ZNF709 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF709 Gene

Genomics for ZNF709 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF709 Gene

Start:
12,461,184 bp from pter
End:
12,513,854 bp from pter
Size:
52,671 bases
Orientation:
Minus strand

Genomic View for ZNF709 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF709 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF709 Gene

Proteins for ZNF709 Gene

  • Protein details for ZNF709 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N972-ZN709_HUMAN
    Recommended name:
    Zinc finger protein 709
    Protein Accession:
    Q8N972
    Secondary Accessions:
    • A8K4E6

    Protein attributes for ZNF709 Gene

    Size:
    641 amino acids
    Molecular mass:
    74652 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF709 Gene

Proteomics data for ZNF709 Gene at MOPED

Post-translational modifications for ZNF709 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF709 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF709 Gene

Domains for ZNF709 Gene

Gene Families for ZNF709 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF709 Gene

Suggested Antigen Peptide Sequences for ZNF709 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N972

UniProtKB/Swiss-Prot:

ZN709_HUMAN :
  • Q8N972
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF709: view

Function for ZNF709 Gene

Molecular function for ZNF709 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF709: view

Phenotypes for ZNF709 Gene

GenomeRNAi human phenotypes for ZNF709:
genes like me logo Genes that share phenotypes with ZNF709: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF709

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF709 Gene

Localization for ZNF709 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF709 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF709 Gene COMPARTMENTS Subcellular localization image for ZNF709 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF709: view

Pathways for ZNF709 Gene

SuperPathways for ZNF709 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF709: view

Pathways by source for ZNF709 Gene

2 Reactome pathways for ZNF709 Gene

Gene Ontology (GO) - Biological Process for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF709: view

Transcripts for ZNF709 Gene

mRNA/cDNA for ZNF709 Gene

Unigene Clusters for ZNF709 Gene

Zinc finger protein 709:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF709

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF709 Gene

No ASD Table

Relevant External Links for ZNF709 Gene

GeneLoc Exon Structure for
ZNF709
ECgene alternative splicing isoforms for
ZNF709

Expression for ZNF709 Gene

mRNA expression in normal human tissues for ZNF709 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF709 Gene

This gene is overexpressed in Testis (9.6).

Protein differential expression in normal tissues for ZNF709 Gene

This gene is overexpressed in Cerebrospinal fluid (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF709 Gene

SOURCE GeneReport for Unigene cluster for ZNF709 Gene Hs.631623

genes like me logo Genes that share expressions with ZNF709: view

Expression partners for ZNF709 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF709 Gene

Orthologs for ZNF709 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF709 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF709 35
  • 74.64 (n)
  • 65.16 (a)
chimpanzee
(Pan troglodytes)
Mammalia ZNF709 35
  • 99.84 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia LOC100911320 35
  • 81.24 (n)
  • 83.31 (a)
mouse
(Mus musculus)
Mammalia Zfp872 16
Zfp872 36
  • 78 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 61 (a)
ManyToMany
Species with no ortholog for ZNF709:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF709 Gene

ENSEMBL:
Gene Tree for ZNF709 (if available)
TreeFam:
Gene Tree for ZNF709 (if available)

Paralogs for ZNF709 Gene

Selected SIMAP similar genes for ZNF709 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF709: view

Variants for ZNF709 Gene

Sequence variations from dbSNP and Humsavar for ZNF709 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs731723 -- 12,477,305(+) attta(C/T)attga intron-variant
rs879456 -- 12,478,688(+) gctgc(C/T)caagc intron-variant
rs1075460 -- 12,477,839(-) CAGGG(A/C)CAAAA intron-variant
rs1075461 -- 12,477,833(-) CAAAA(A/C)CAAAA intron-variant
rs1075462 -- 12,477,827(-) CAAAA(A/C)CAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF709 Gene

Variant ID Type Subtype PubMed ID
nsv911075 CNV Loss 21882294

Relevant External Links for ZNF709 Gene

HapMap Linkage Disequilibrium report
ZNF709

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF709 Gene

Disorders for ZNF709 Gene

Relevant External Links for ZNF709

Genetic Association Database (GAD)
ZNF709

No disorders were found for ZNF709 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF709 Gene

Publications for ZNF709 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. (PMID: 16737952) Fang Z. … Yao X. (Mol. Cell Proteomics 2006) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PMID: 22797925) Aichem A. … Groettrup M. (J. Cell. Sci. 2012) 3

Products for ZNF709 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF709
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF709
  • Block miRNA regulation of ZNF709 using miScript Target Protectors

Sources for ZNF709 Gene

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