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Aliases for ZNF709 Gene

Aliases for ZNF709 Gene

  • Zinc Finger Protein 709 2 3 5

External Ids for ZNF709 Gene

Previous GeneCards Identifiers for ZNF709 Gene

  • GC19M012434
  • GC19M012571
  • GC19M012145

Summaries for ZNF709 Gene

GeneCards Summary for ZNF709 Gene

ZNF709 (Zinc Finger Protein 709) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF709 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF709 Gene

Genomics for ZNF709 Gene

Regulatory Elements for ZNF709 Gene

Enhancers for ZNF709 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF709 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF709 Gene

Chromosome:
19
Start:
12,461,184 bp from pter
End:
12,513,854 bp from pter
Size:
52,671 bases
Orientation:
Minus strand

Genomic View for ZNF709 Gene

Genes around ZNF709 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF709 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF709 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF709 Gene

Proteins for ZNF709 Gene

  • Protein details for ZNF709 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N972-ZN709_HUMAN
    Recommended name:
    Zinc finger protein 709
    Protein Accession:
    Q8N972
    Secondary Accessions:
    • A8K4E6

    Protein attributes for ZNF709 Gene

    Size:
    641 amino acids
    Molecular mass:
    74652 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF709 Gene

Post-translational modifications for ZNF709 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF709 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF709 Gene

Domains & Families for ZNF709 Gene

Gene Families for ZNF709 Gene

Protein Domains for ZNF709 Gene

Suggested Antigen Peptide Sequences for ZNF709 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N972

UniProtKB/Swiss-Prot:

ZN709_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF709: view

Function for ZNF709 Gene

Molecular function for ZNF709 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF709: view
genes like me logo Genes that share phenotypes with ZNF709: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF709 Gene

Localization for ZNF709 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF709 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF709 Gene COMPARTMENTS Subcellular localization image for ZNF709 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF709: view

Pathways & Interactions for ZNF709 Gene

SuperPathways for ZNF709 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF709: view

Pathways by source for ZNF709 Gene

2 Reactome pathways for ZNF709 Gene

Gene Ontology (GO) - Biological Process for ZNF709 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF709: view

No data available for SIGNOR curated interactions for ZNF709 Gene

Drugs & Compounds for ZNF709 Gene

No Compound Related Data Available

Transcripts for ZNF709 Gene

mRNA/cDNA for ZNF709 Gene

Unigene Clusters for ZNF709 Gene

Zinc finger protein 709:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF709 Gene

No ASD Table

Relevant External Links for ZNF709 Gene

GeneLoc Exon Structure for
ZNF709
ECgene alternative splicing isoforms for
ZNF709

Expression for ZNF709 Gene

mRNA expression in normal human tissues for ZNF709 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF709 Gene

This gene is overexpressed in Testis (x9.6).

Protein differential expression in normal tissues from HIPED for ZNF709 Gene

This gene is overexpressed in Cerebrospinal fluid (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF709 Gene



Protein tissue co-expression partners for ZNF709 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF709 Gene:

ZNF709

SOURCE GeneReport for Unigene cluster for ZNF709 Gene:

Hs.631623
genes like me logo Genes that share expression patterns with ZNF709: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF709 Gene

Orthologs for ZNF709 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF709 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF709 34
  • 74.64 (n)
  • 65.16 (a)
chimpanzee
(Pan troglodytes)
Mammalia ZNF709 34
  • 99.84 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia LOC100911320 34
  • 81.24 (n)
  • 83.31 (a)
cow
(Bos Taurus)
Mammalia -- 35
  • 61 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp872 35
  • 78 (a)
OneToMany
Species where no ortholog for ZNF709 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF709 Gene

ENSEMBL:
Gene Tree for ZNF709 (if available)
TreeFam:
Gene Tree for ZNF709 (if available)

Paralogs for ZNF709 Gene

(451) SIMAP similar genes for ZNF709 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF709: view

Variants for ZNF709 Gene

Sequence variations from dbSNP and Humsavar for ZNF709 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17776923 -- 12,473,072(+) CTCCA(C/T)TGCTA intron-variant
rs11085814 -- 12,463,762(+) TCTCT(A/C)CTAAA utr-variant-3-prime
rs28632001 -- 12,467,832(+) gccgc(A/G)acccc intron-variant
rs28678799 -- 12,479,076(+) GGCAG(A/G)AGGAT intron-variant
rs34002005 -- 12,485,205(+) ATGGA(-/TT)TCTGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF709 Gene

Variant ID Type Subtype PubMed ID
dgv3436n100 CNV gain 25217958
dgv3437n100 CNV gain 25217958
nsv1059260 CNV loss 25217958
nsv1063081 CNV gain 25217958
nsv1066523 CNV gain 25217958
nsv1113975 CNV deletion 24896259
nsv963008 CNV duplication 23825009

Variation tolerance for ZNF709 Gene

Residual Variation Intolerance Score: 16.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.79; 16.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF709 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF709

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF709 Gene

Disorders for ZNF709 Gene

Relevant External Links for ZNF709

Genetic Association Database (GAD)
ZNF709
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF709

No disorders were found for ZNF709 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF709 Gene

Publications for ZNF709 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  3. Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. (PMID: 16737952) Fang Z. … Yao X. (Mol. Cell Proteomics 2006) 3 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for ZNF709 Gene

Sources for ZNF709 Gene

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