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Aliases for ZNF707 Gene

Aliases for ZNF707 Gene

  • Zinc Finger Protein 707 2 3 5

External Ids for ZNF707 Gene

Previous GeneCards Identifiers for ZNF707 Gene

  • GC08P144825
  • GC08P144838
  • GC08P144766
  • GC08P140019

Summaries for ZNF707 Gene

GeneCards Summary for ZNF707 Gene

ZNF707 (Zinc Finger Protein 707) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZFP92.

UniProtKB/Swiss-Prot for ZNF707 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF707 Gene

Genomics for ZNF707 Gene

Regulatory Elements for ZNF707 Gene

Enhancers for ZNF707 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F143683 1.1 ENCODE 5.9 +0.3 291 1.7 PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF207 ZNF143 LRRC14 ZNF623 ADCK5 VPS28 BREA2 LOC105375803 ZNF696 ZNF707 GSDMD
GH08F143681 0.4 ENCODE 7.6 -2.6 -2647 0.2 ZNF680 SCRT2 ZNF623 ZNF707 LOC105375799
GH08F143703 0.5 ENCODE 5.6 +18.8 18770 0.4 BCOR MCM7 RNF2 TRIM24 ZNF707 LOC101928160 PIR46420
GH08F143275 1.6 FANTOM5 ENCODE 1.5 -405.4 -405378 6.5 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 MINCR ZNF623 ZFP41 RHPN1 HGH1 FAM83H-AS1 TOP1MT ZC3H3 TIGD5 GLI4
GH08F143689 0.7 ENCODE 0.8 +4.7 4654 0.2 KLF1 PKNOX1 ZBTB11 ZNF121 TFDP1 ZFHX2 GATA3 GATA2 PATZ1 IKZF1 ZNF707 BREA2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF707 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF707 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001404200 348 1601 PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF143 FOS

Genomic Location for ZNF707 Gene

Chromosome:
8
Start:
143,684,452 bp from pter
End:
143,713,898 bp from pter
Size:
29,447 bases
Orientation:
Plus strand

Genomic View for ZNF707 Gene

Genes around ZNF707 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF707 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF707 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF707 Gene

Proteins for ZNF707 Gene

  • Protein details for ZNF707 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96C28-ZN707_HUMAN
    Recommended name:
    Zinc finger protein 707
    Protein Accession:
    Q96C28
    Secondary Accessions:
    • A8K317
    • B3KNY1
    • D3DWK7

    Protein attributes for ZNF707 Gene

    Size:
    371 amino acids
    Molecular mass:
    43088 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH14894.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAF83121.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF707 Gene

Post-translational modifications for ZNF707 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF707 Gene

Domains & Families for ZNF707 Gene

Gene Families for ZNF707 Gene

Protein Domains for ZNF707 Gene

Suggested Antigen Peptide Sequences for ZNF707 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96C28

UniProtKB/Swiss-Prot:

ZN707_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF707: view

Function for ZNF707 Gene

Molecular function for ZNF707 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF707 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF707: view
genes like me logo Genes that share phenotypes with ZNF707: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF707 Gene

Localization for ZNF707 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF707 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF707 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF707 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF707: view

Pathways & Interactions for ZNF707 Gene

SuperPathways for ZNF707 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF707: view

Pathways by source for ZNF707 Gene

2 Reactome pathways for ZNF707 Gene

Gene Ontology (GO) - Biological Process for ZNF707 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF707: view

No data available for SIGNOR curated interactions for ZNF707 Gene

Transcripts for ZNF707 Gene

Unigene Clusters for ZNF707 Gene

Zinc finger protein 707:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF707 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c · 9d · 9e · 9f ^ 10a · 10b · 10c · 10d · 10e ^
SP1: - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - -
SP6: - - - - -
SP7: - - - - - - - -
SP8: - - - - - - - - - - - - - - -
SP9: - - - - - - - - -
SP10: - - - - - - - - -
SP11: - - - - - - - - - - - - - - - - - - - -
SP12: - - - - - - - - - - - - - - - - - - -
SP13: - - - - - - - - - -
SP14: - - - -
SP15: - - - - - - - - - - - -
SP16: - - - - -
SP17: - - - - - - -
SP18: - - -

ExUns: 11a · 11b · 11c · 11d · 11e · 11f
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for ZNF707 Gene

GeneLoc Exon Structure for
ZNF707
ECgene alternative splicing isoforms for
ZNF707

Expression for ZNF707 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF707 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF707 Gene



Protein tissue co-expression partners for ZNF707 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF707 Gene:

ZNF707

SOURCE GeneReport for Unigene cluster for ZNF707 Gene:

Hs.521922
genes like me logo Genes that share expression patterns with ZNF707: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF707 Gene

Orthologs for ZNF707 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF707 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF707 34 35
  • 98.83 (n)
mouse
(Mus musculus)
Mammalia Zfp707 34 16 35
  • 74.43 (n)
rat
(Rattus norvegicus)
Mammalia RGD1311188 34
  • 71.95 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 32 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 31 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 34 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 24 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ZAP1 35
  • 9 (a)
OneToMany
Species where no ortholog for ZNF707 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF707 Gene

ENSEMBL:
Gene Tree for ZNF707 (if available)
TreeFam:
Gene Tree for ZNF707 (if available)

Paralogs for ZNF707 Gene

Paralogs for ZNF707 Gene

(437) SIMAP similar genes for ZNF707 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with ZNF707: view

Variants for ZNF707 Gene

Sequence variations from dbSNP and Humsavar for ZNF707 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10093252 -- 143,693,320(+) CTGTC(A/G)CCCAG intron-variant
rs10094956 -- 143,683,898(+) ctacc(A/G)gtctc upstream-variant-2KB
rs10453144 -- 143,683,561(+) gcctg(C/G)ccgca upstream-variant-2KB
rs10707160 -- 143,695,573(+) GTCTC(-/A)AAAAA intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs111256087 -- 143,682,874(+) ACCTC(A/G)TGATC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF707 Gene

Variant ID Type Subtype PubMed ID
esv2738031 CNV deletion 23290073
esv2738032 CNV deletion 23290073
esv2738033 CNV deletion 23290073
esv2738034 CNV deletion 23290073
esv3619115 CNV loss 21293372
nsv466007 CNV loss 19166990
nsv519816 CNV loss 19592680
nsv612893 CNV loss 21841781

Variation tolerance for ZNF707 Gene

Residual Variation Intolerance Score: 56.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.85; 34.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF707 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF707

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF707 Gene

Disorders for ZNF707 Gene

Relevant External Links for ZNF707

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF707

No disorders were found for ZNF707 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF707 Gene

Publications for ZNF707 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64

Products for ZNF707 Gene

Sources for ZNF707 Gene

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