ZNF706 Gene
protein-coding GIFtS: 46
GCID: GC08M102190
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|
zinc finger protein 706
| |
Aliases
for ZNF706 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 7061 2 | | HSPC0381 | | PNAS-1062 | | PNAS-1132 |
Export aliases for ZNF706 gene to outside databasesPrevious GC identifers: GC08M102280 GC08M097407 |
Summaries
for ZNF706 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZNF706 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF706 gene promoter:
FOXO3a FOXO3 FOXJ2 ZID Pax-4a FOXO3b
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF706
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF706 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q22.3 Ensembl cytogenetic band: 8q22.3 HGNC cytogenetic band: 8q22.3ZNF706 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M102190: view genomic region
(about GC identifiers)
Start:
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102,190,106 bp from pter |
End:
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102,218,421 bp from pter |
Size:
|
28,316 bases |
Orientation:
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minus strand |
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Proteins
for ZNF706 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN706_HUMAN, Q9Y5V0 (See
protein sequence)Recommended Name: Zinc finger protein 706 Size: 76 amino acids; 8498 Da
Secondary accessions: A8K362Explore the universe of human proteins at neXtProt for ZNF706: NX_Q9Y5V0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y5V0
ZNF706 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001035975.1 NP_001254637.1 NP_001254638.1 NP_057180.1
ENSEMBL proteins: ENSP00000427761 ENSP00000431059 ENSP00000311768 ENSP00000429645 ENSP00000428227 ENSP00000427803 ENSP00000430823 ENSP00000428985 ENSP00000430165 ENSP00000428696 ENSP00000430845 ENSP00000429260 ENSP00000430090 Reactome Protein details: Q9Y5V0
Human Recombinant Protein Products for ZNF706:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IEA | -- |
ZNF706 for ontologies About GeneDecksing
ZNF706 Antibody Products:
Assay Products for ZNF706: |
Protein
Domains /
Families
for ZNF706 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF706 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y5V0ProtoNet protein and cluster: Q9Y5V0 UniProtKB/Swiss-Prot: ZN706_HUMAN, Q9Y5V0Similarity: Contains 1 C2H2-type zinc finger |
Function
for ZNF706 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- |
ZNF706 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF706 (NM_016096) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF706 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF706 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF706 |
|
Pathways & Interactions
for ZNF706 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF706
ZNF706 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF706
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/9 Interacting proteins for ZNF706 (Q9Y5V03 ENSP000003117684) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
|
Drugs & Compounds
for ZNF706 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF706
Search CenterWatch for drugs/clinical trials and news about ZNF706 / ZN706
|
Transcripts
for ZNF706 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF706 gene (4 alternative transcripts): NM_001042510.1 NM_001267708.1 NM_001267709.1 NM_016096.3 Unigene Cluster for ZNF706: Zinc finger protein 706 Hs.374485 [show with all ESTs]Unigene Representative Sequence: NM_00126770815 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000520984 ENST00000518071 ENST00000311212(uc003yka.3 uc003ykb.3)
ENST00000519744 ENST00000520498 ENST00000517844 ENST00000519103 ENST00000520347
ENST00000519882 ENST00000521272 ENST00000518336 ENST00000523146 ENST00000519916
ENST00000523922 ENST00000520454
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF706 (NM_016096) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF706 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF706 |
Additional cDNA sequence: AF125099.1 AF275802.1 AF275809.1 AK129859.1 AK290477.1 BC015925.1 BC068524.1 19 DOTS entries: DT.91987058 DT.448346 DT.95177681 DT.100037906 DT.91646352 DT.91751429 DT.100795093 DT.95177683 DT.121485951 DT.91751423 DT.100037904 DT.100736092 DT.100795096 DT.40215756 DT.91696954 DT.91744107 DT.100795095 DT.91751425 DT.91848003 24/321 AceView cDNA sequences (see all 321): F05847 BX497930 BM973865 AA250840 F02095 CA431354 BQ015513 AI378407 AA932784 AA055283 AA243570 CB178582 AI824335 BM466131 BM711156 AA292359 BM669735 AI093660 BM055237 W81271 CA313319 W81234 BU634143 AI868453
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF706 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 |
|---|
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| SP1: | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | |
| SP3: | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF706
|
Expression
for ZNF706 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF706 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAAGACAAT
About this image
See ZNF706 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF706
SOURCE GeneReport for Unigene cluster: Hs.374485
SABiosciences Custom PCR Arrays for ZNF706
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF706
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF706 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF706 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF706 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF706 |
Orthologs
for ZNF706 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF706 gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for ZNF706 (if available)
TreeFam Gene Tree for ZNF706 (if available) |
Paralogs
for ZNF706 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF706 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF706 (102190106 - 102218421 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF706: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF706 |
|
Disorders
/ Diseases
for ZNF706 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF706 for disorders About GeneDecksing
5  diseases for ZNF706: About MalaCardslaryngeal squamous cell carcinoma squamous cell carcinoma laryngitis carcinoma
schizophrenia
1 disease from the University of Copenhagen DISEASES database for ZNF706:Laryngeal squamous cell carcinoma Export disorders for ZNF706 gene to outside databases
|
Publications
for ZNF706 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF706 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF706) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume. (PubMed id 21917931)1 Dossena S....Paulmichl M. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Genome-wide pharmacogenomic study of neurocognition a s an indicator of antipsychotic treatment response in schizophrenia. (PubMed id 21107309)1 McClay J.L....van den Oord E.J. (2011)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF706 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF706 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF706 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF706 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF706 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF706 gene:
Search GeneIP for patents involving ZNF706
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF706 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF706 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF706 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF706 | | | OriGene Protein Over-expression Lysate for ZNF706 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF706 | | OriGene 3'-UTR Clone for ZNF706 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF706 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZNF706 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF706 | | OriGene Custom Protein Services for ZNF706 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF706 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF706 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF706 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF706 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF706 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF706 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF706 |
| |  |  |  |  | | | | |
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 | | | ZNF706 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF706 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF706 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF706 |
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