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Aliases for ZNF705D Gene

Aliases for ZNF705D Gene

  • Zinc Finger Protein 705D 2 3 5
  • Putative Zinc Finger Protein 705C 3
  • Zinc Finger Protein 705C 3
  • ZNF705C 3

External Ids for ZNF705D Gene

Previous GeneCards Identifiers for ZNF705D Gene

  • GC08U900805
  • GC08P011985
  • GC08P011946

Summaries for ZNF705D Gene

GeneCards Summary for ZNF705D Gene

ZNF705D (Zinc Finger Protein 705D) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF705G.

UniProtKB/Swiss-Prot for ZNF705D Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705D Gene

Genomics for ZNF705D Gene

Regulatory Elements for ZNF705D Gene


Genomic Location for ZNF705D Gene

Chromosome:
8
Start:
12,089,338 bp from pter
End:
12,115,516 bp from pter
Size:
26,179 bases
Orientation:
Plus strand

Genomic View for ZNF705D Gene

Genes around ZNF705D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705D Gene

Proteins for ZNF705D Gene

  • Protein details for ZNF705D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CH99-Z705D_HUMAN
    Recommended name:
    Zinc finger protein 705D
    Protein Accession:
    P0CH99
    Secondary Accessions:
    • A8K971
    • A8MY01
    • Q2TAN0

    Protein attributes for ZNF705D Gene

    Size:
    300 amino acids
    Molecular mass:
    34712 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705D Gene

Proteomics data for ZNF705D Gene at MOPED

Post-translational modifications for ZNF705D Gene

No Post-translational modifications

Other Protein References for ZNF705D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF705D Gene

Domains & Families for ZNF705D Gene

Gene Families for ZNF705D Gene

Protein Domains for ZNF705D Gene

Suggested Antigen Peptide Sequences for ZNF705D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CH99

UniProtKB/Swiss-Prot:

Z705D_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 4 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF705D: view

Function for ZNF705D Gene

Molecular function for ZNF705D Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF705D Gene

GenomeRNAi human phenotypes for ZNF705D:
genes like me logo Genes that share phenotypes with ZNF705D: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF705D Gene

Localization for ZNF705D Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705D Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF705D Gene COMPARTMENTS Subcellular localization image for ZNF705D gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF705D Gene

Pathways & Interactions for ZNF705D Gene

SuperPathways for ZNF705D Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF705D: view

Pathways by source for ZNF705D Gene

2 Reactome pathways for ZNF705D Gene

Interacting Proteins for ZNF705D Gene

Gene Ontology (GO) - Biological Process for ZNF705D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705D: view

No data available for SIGNOR curated interactions for ZNF705D Gene

Drugs & Compounds for ZNF705D Gene

No Compound Related Data Available

Transcripts for ZNF705D Gene

mRNA/cDNA for ZNF705D Gene

(5) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF705D Gene

Zinc finger protein 705D:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705D Gene

No ASD Table

Relevant External Links for ZNF705D Gene

GeneLoc Exon Structure for
ZNF705D
ECgene alternative splicing isoforms for
ZNF705D

Expression for ZNF705D Gene

mRNA expression in normal human tissues for ZNF705D Gene

mRNA differential expression in normal tissues according to GTEx for ZNF705D Gene

This gene is overexpressed in Testis (x42.5) and Brain - Caudate (basal ganglia) (x5.6).

SOURCE GeneReport for Unigene cluster for ZNF705D Gene Hs.652228

genes like me logo Genes that share expression patterns with ZNF705D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF705D Gene

Orthologs for ZNF705D Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF705D Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF705A 35
  • 73.83 (n)
  • 60.07 (a)
-- 36
  • 28 (a)
ManyToMany
ZNF705A 36
  • 55 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia LOC482938 35
  • 74.22 (n)
  • 60.67 (a)
-- 36
  • 56 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 95 (a)
OneToMany
Species with no ortholog for ZNF705D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705D Gene

ENSEMBL:
Gene Tree for ZNF705D (if available)
TreeFam:
Gene Tree for ZNF705D (if available)

Paralogs for ZNF705D Gene

Paralogs for ZNF705D Gene

(335) SIMAP similar genes for ZNF705D Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF705D: view

Variants for ZNF705D Gene

Sequence variations from dbSNP and Humsavar for ZNF705D Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs3914902 -- 12,109,988(+) CAGAG(A/T)TGTGA intron-variant, reference, missense
rs3926070 -- 12,113,758(+) TTGAT(A/G)TTCAC utr-variant-3-prime
rs4081032 -- 12,093,254(-) GGACA(C/T)GTATA intron-variant
rs11985862 -- 12,095,158(+) AAACC(A/T)CCAGA intron-variant
rs4841733 -- 12,089,644(+) AGATC(A/G)TATGT upstream-variant-2KB, splice-donor-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF705D Gene

Variant ID Type Subtype PubMed ID
nsv516685 CNV Gain+Loss 19592680
nsv428195 CNV Gain 18775914
dgv2199e1 CNV Complex 17122850
dgv2200e1 CNV Complex 17122850
esv2736614 CNV Deletion 23290073
essv15113 CNV CNV 17122850
nsv890372 CNV Gain 21882294
dgv27n31 CNV Duplication 19718026
dgv1270e199 CNV Deletion 23128226
nsv890373 CNV Loss 21882294
dgv2201e1 CNV Complex 17122850
esv2660145 CNV Deletion 23128226
esv22986 CNV Gain+Loss 19812545
dgv244e55 CNV Gain 17911159
nsv890374 CNV Gain 21882294
nsv8288 CNV Gain+Loss 18304495
nsv471461 CNV Duplication 19718026

Variation tolerance for ZNF705D Gene

Gene Damage Index Score: 0.08; 1.90% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF705D Gene

Disorders for ZNF705D Gene

Relevant External Links for ZNF705D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF705D

No disorders were found for ZNF705D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705D Gene

Publications for ZNF705D Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF705D Gene

Sources for ZNF705D Gene

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