ZNF705A Gene
protein-coding GIFtS: 38
GCID: GC12P008290
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zinc finger protein 705A
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Aliases
for ZNF705A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 705A1 2 | | FLJ163531 |
Export aliases for ZNF705A gene to outside databasesPrevious GC identifers: GC12P008217 GC12P008140 GC12P008218 GC12P008276 GC12P008137 |
Summaries
for ZNF705A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: Z705A_HUMAN, Q6ZN79Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF705A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009714.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF705A gene promoter:
AREB6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF705A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF705A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p13.31 Ensembl cytogenetic band: 12p13.31 HGNC cytogenetic band: 12p13.31ZNF705A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P008290: view genomic region
(about GC identifiers)
Start:
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8,290,733 bp from pter |
End:
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8,332,642 bp from pter |
Size:
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41,910 bases |
Orientation:
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plus strand |
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Proteins
for ZNF705A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: Z705A_HUMAN, Q6ZN79 (See
protein sequence)Recommended Name: Zinc finger protein 705A Size: 300 amino acids; 34734 Da
Subcellular location: Nucleus (Potential)Explore the universe of human proteins at neXtProt for ZNF705A: NX_Q6ZN79
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZN79
ZNF705A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001004328.1
ENSEMBL proteins: ENSP00000384896 ENSP00000379816 ENSP00000352233 Reactome Protein details: Q6ZN79
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF705A for ontologies About GeneDecksing
ZNF705A Antibody Products:
Assay Products for ZNF705A: |
Protein
Domains /
Families
for ZNF705A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF705A for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZN79ProtoNet protein and cluster: Q6ZN79 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: Z705A_HUMAN, Q6ZN79Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 3 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF705A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: Z705A_HUMAN, Q6ZN79Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF705A (NM_001004328) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF705A | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF705A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF705A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF705A for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF705A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF705A
ZNF705A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF705A
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF705A for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF705A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF705A
Search CenterWatch for drugs/clinical trials and news about ZNF705A / Z705A
|
Transcripts
for ZNF705A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF705A gene: NM_001004328.2 Unigene Cluster for ZNF705A: Zinc finger protein 705A Hs.438536 [show with all ESTs]Unigene Representative Sequence: NM_0010043283 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000402465 ENST00000396570 ENST00000359286(uc001qud.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF705A (NM_001004328) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF705A | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF705A |
3 DOTS entries: DT.102842415 DT.121173719 DT.121173752 3 AceView cDNA sequences: AK131339 NM_001004328 BG203970
GeneLoc Exon Structure
|
Expression
for ZNF705A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF705A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF705A Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.438536
SABiosciences Custom PCR Arrays for ZNF705A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF705A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ZNF705A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF705A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF705A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF705A |
Orthologs
for ZNF705A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF705A gene from 1/5 species (see all 5) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
12(a) |
1 → many |
GL343915.1(63411-81262) |
ENSEMBL Gene Tree for ZNF705A (if available)
TreeFam Gene Tree for ZNF705A (if available) |
Paralogs
for ZNF705A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF705A gene
- ZNF705G2 ZNF705D2 LOC7284292 ZNF705B2 ZNF5962
18/414 SIMAP similar genes for ZNF705A using alignment to 3 protein entries: Z705A_HUMAN (see all proteins)
(see all similar genes):ZNF705G ZNF705D ZNF705F ZNF705E ZNF317 ZNF81
ZNF561 ZNF559 ZNF10 ZNF225 ZNF230 ZNF554
ZNF776 ZFP90 ZNF124 ZNF761 ZNF224 ZNF529
ZNF705A for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF705A
PGOHUM00000258570 PGOHUM00000246011
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Genomic Variants
for ZNF705A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF705A (8290733 - 8332642 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for ZNF705A
8 CNVs: 71455 86176 75924 71457 2969 3873 34469 30580 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF705A |
|
Disorders
/ Diseases
for ZNF705A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF705A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for ZNF705A gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF705A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for ZNF705A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZNF705A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF705A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF705A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF705A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF705A gene:
Search GeneIP for patents involving ZNF705A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF705A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF705A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF705A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF705A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF705A | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF705A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF705A | | OriGene Custom Protein Services for ZNF705A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF705A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF705A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF705A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF705A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF705A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF705A |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF705A |
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 | | | ZNF705A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF705A |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF705A |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF705A |
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