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Aliases for ZNF705A Gene

Aliases for ZNF705A Gene

  • Zinc Finger Protein 705A 2 3 5

External Ids for ZNF705A Gene

Previous GeneCards Identifiers for ZNF705A Gene

  • GC12P008217
  • GC12P008140
  • GC12P008218
  • GC12P008276
  • GC12P008290

Summaries for ZNF705A Gene

GeneCards Summary for ZNF705A Gene

ZNF705A (Zinc Finger Protein 705A) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF705G.

UniProtKB/Swiss-Prot for ZNF705A Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF705A Gene

Genomics for ZNF705A Gene

Regulatory Elements for ZNF705A Gene

Transcription factor binding sites by QIAGEN in the ZNF705A gene promoter:

Genomic Location for ZNF705A Gene

Chromosome:
12
Start:
8,138,137 bp from pter
End:
8,188,537 bp from pter
Size:
50,401 bases
Orientation:
Plus strand

Genomic View for ZNF705A Gene

Genes around ZNF705A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF705A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF705A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF705A Gene

Proteins for ZNF705A Gene

  • Protein details for ZNF705A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN79-Z705A_HUMAN
    Recommended name:
    Zinc finger protein 705A
    Protein Accession:
    Q6ZN79

    Protein attributes for ZNF705A Gene

    Size:
    300 amino acids
    Molecular mass:
    34734 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF705A Gene

Proteomics data for ZNF705A Gene at MOPED

Post-translational modifications for ZNF705A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF705A Gene

No data available for DME Specific Peptides for ZNF705A Gene

Domains & Families for ZNF705A Gene

Gene Families for ZNF705A Gene

Protein Domains for ZNF705A Gene

Suggested Antigen Peptide Sequences for ZNF705A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZN79

UniProtKB/Swiss-Prot:

Z705A_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 3 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF705A: view

Function for ZNF705A Gene

Molecular function for ZNF705A Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF705A Gene

GenomeRNAi human phenotypes for ZNF705A:
genes like me logo Genes that share phenotypes with ZNF705A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF705A Gene

Localization for ZNF705A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF705A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF705A Gene COMPARTMENTS Subcellular localization image for ZNF705A gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF705A Gene

Pathways & Interactions for ZNF705A Gene

SuperPathways for ZNF705A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF705A: view

Pathways by source for ZNF705A Gene

2 Reactome pathways for ZNF705A Gene

Interacting Proteins for ZNF705A Gene

Gene Ontology (GO) - Biological Process for ZNF705A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF705A: view

No data available for SIGNOR curated interactions for ZNF705A Gene

Drugs & Compounds for ZNF705A Gene

No Compound Related Data Available

Transcripts for ZNF705A Gene

mRNA/cDNA for ZNF705A Gene

(4) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF705A Gene

Zinc finger protein 705A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF705A Gene

No ASD Table

Relevant External Links for ZNF705A Gene

GeneLoc Exon Structure for
ZNF705A
ECgene alternative splicing isoforms for
ZNF705A

Expression for ZNF705A Gene

mRNA expression in normal human tissues for ZNF705A Gene

mRNA differential expression in normal tissues according to GTEx for ZNF705A Gene

This gene is overexpressed in Testis (x13.1).

SOURCE GeneReport for Unigene cluster for ZNF705A Gene Hs.438536

genes like me logo Genes that share expression patterns with ZNF705A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF705A Gene

Orthologs for ZNF705A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF705A Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Clec4a1 35
Clec4a1 16
chimpanzee
(Pan troglodytes)
Mammalia ZNF705A 35
  • 99.33 (n)
  • 98.66 (a)
ZNF705A 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Clec4a1 35
cow
(Bos Taurus)
Mammalia -- 36
  • 28 (a)
ManyToMany
ZNF705A 36
  • 56 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 57 (a)
OneToMany
Species with no ortholog for ZNF705A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF705A Gene

ENSEMBL:
Gene Tree for ZNF705A (if available)
TreeFam:
Gene Tree for ZNF705A (if available)

Paralogs for ZNF705A Gene

Paralogs for ZNF705A Gene

(451) SIMAP similar genes for ZNF705A Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF705A Gene

genes like me logo Genes that share paralogs with ZNF705A: view

Variants for ZNF705A Gene

Sequence variations from dbSNP and Humsavar for ZNF705A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10743253 - 8,177,104(+) GAAAG(A/C)AACCC reference, missense
rs10743251 - 8,177,056(+) ATTGC(A/G)CTCAC reference, missense
rs10743252 - 8,177,080(+) CTCAG(C/T)GTTTG reference, missense
rs11043758 - 8,177,237(+) CTTTC(A/G)CCTTA reference, missense
rs4331180 -- 8,161,667(+) AGGTG(A/G/T)AAAGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF705A Gene

Variant ID Type Subtype PubMed ID
dgv455e1 CNV Complex 17122850
nsv428270 CNV Gain 18775914
dgv459e1 CNV Complex 17122850
dgv460e1 CNV Complex 17122850
dgv461e1 CNV Complex 17122850
nsv8899 CNV Gain+Loss 18304495
esv29886 CNV Gain+Loss 19812545
dgv462e1 CNV Complex 17122850
nsv826226 CNV Gain 20364138
nsv471365 CNV Duplication 19718026
dgv463e1 CNV Complex 17122850

Variation tolerance for ZNF705A Gene

Residual Variation Intolerance Score: 81.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.18; 84.81% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF705A Gene

HapMap Linkage Disequilibrium report
ZNF705A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF705A Gene

Disorders for ZNF705A Gene

Relevant External Links for ZNF705A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF705A

No disorders were found for ZNF705A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF705A Gene

Publications for ZNF705A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67

Products for ZNF705A Gene

Sources for ZNF705A Gene

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