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ZNF703 Gene

protein-coding   GIFtS: 48
GCID: GC08P037553

Zinc Finger Protein 703

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 7031 2
Zinc Finger Elbow-Related Proline Domain Protein 12 3
ZEPPO12 3
ZPO12 3
ZNF503L2

External Ids:    HGNC: 258831   Entrez Gene: 801392   Ensembl: ENSG000001837797   UniProtKB: Q9H7S93   

Export aliases for ZNF703 gene to outside databases

Previous GC identifers: GC08P037673 GC08P036088


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF703 Gene:
ZNF703 (zinc finger protein 703) is a protein-coding gene. GO annotations related to this gene include repressing transcription factor binding and nucleic acid binding. An important paralog of this gene is ZNF503.

UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
Function: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through
recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May
be required for segmental gene expression during hindbrain development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF703 gene promoter:
         Elk-1   Spz1   LHX3b/Lhx3b   Pax-5   Olf-1   COMP1   FOXO4   LHX3a/Lhx3a   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF703 promoter sequence
   Search Chromatin IP Primers for ZNF703

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF703


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p11.23   Ensembl cytogenetic band:  8p11.23   HGNC cytogenetic band: 8p12

ZNF703 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF703 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P037553:  view genomic region     (about GC identifiers)

Start:
37,553,269 bp from pter      End:
37,557,537 bp from pter
Size:
4,269 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9 (See protein sequence)
Recommended Name: Zinc finger protein 703  
Size: 590 amino acids; 58222 Da
Subunit: Interacts with TLE4; increases transcriptional repression (By similarity). Interacts with DCAF7 and PHB2.
May interact with HSPD1
Sequence caution: Sequence=AAH84581.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: Q5XG76

Explore the universe of human proteins at neXtProt for ZNF703: NX_Q9H7S9

Explore proteomics data for ZNF703 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF703 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079345.1  
    ENSEMBL proteins: 
     ENSP00000332325  
    Reactome Protein details: Q9H7S9

    ZNF703 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF703

     
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    antibodies-online antibodies for ZNF703 (26 products) 

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    Cloud-Clone Corp. ELISAs for ZNF703
    Cloud-Clone Corp. CLIAs for ZNF703
    Search eBioscience for ELISAs for ZNF703 
    antibodies-online kits for ZNF703 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR022129 Tscrpt_rep_NocA-like
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9H7S9

    ProtoNet protein and cluster: Q9H7S9

    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
    Similarity: Belongs to the Elbow/Noc family
    Similarity: Contains 1 C2H2-type zinc finger


    Find genes that share domains with ZNF703           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN703_HUMAN, Q9H7S9
    Function: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through
    recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May
    be required for segmental gene expression during hindbrain development
    Induction: Up-regulated by 17-beta-estradiol

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI--
    GO:0046872metal ion binding IEA--
    GO:0070491repressing transcription factor binding IEA--
         
    Find genes that share ontologies with ZNF703           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF703:
     Cell cycle / mitosis defect 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF703

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZNF703:
    hsa-mir-760 (MIRT036709), hsa-mir-18a-5p (MIRT050650), hsa-mir-93-3p (MIRT038858), hsa-mir-92a-3p (MIRT049534), hsa-mir-542-5p (MIRT039352), hsa-mir-26a-5p (MIRT050098), hsa-mir-296-3p (MIRT038483), hsa-mir-425-3p (MIRT042430)

    Block miRNA regulation of human, mouse, rat ZNF703 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ZNF703:
    hsa-miR-569 hsa-miR-3938 hsa-miR-4325 hsa-miR-155 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidZNF703 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF703

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    eBioscience FlowRNA Probe Sets ( VA1-13640) for ZNF703 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN703_HUMAN, Q9H7S9: Nucleus. Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm ISS--
    GO:0016363nuclear matrix IDA--
    GO:0043234protein complex IDA--

    Find genes that share ontologies with ZNF703           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF703 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF703           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for ZNF703
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF703
    Interactions:

        Search GeneGlobe Interaction Network for ZNF703

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ZNF703 (Q9H7S93 ENSP000003323254) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IDA--
    GO:0008284positive regulation of cell proliferation IDA--
    GO:0010718positive regulation of epithelial to mesenchymal transition ISS--
    GO:0017015regulation of transforming growth factor beta receptor signaling pathway IDA--

    Find genes that share ontologies with ZNF703           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF703 (ZN703)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF703 gene: 
    NM_025069.1  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000331569(uc003xjy.1)
    miRNA
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    Block miRNA regulation of human, mouse, rat ZNF703 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ZNF703:
    hsa-miR-569 hsa-miR-3938 hsa-miR-4325 hsa-miR-155 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidZNF703 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ZNF703
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF703
    Clone
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    OriGene clones in human, mouse for ZNF703 (see all 8)
    OriGene ORF clones in mouse, rat for ZNF703
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF703 (NM_025069)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF703
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF703
    Primer
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    OriGene qPCR primer pairs and template standards for ZNF703
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF703
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF703
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF703
      QuantiFast Probe-based Assays in human, mouse, rat ZNF703
    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA1-13640) for ZNF703 

    Selected AceView cDNA sequences (see all 139):

    T50010 NM_025069 BM758730 BM743888 H49609 BM758052 BM770319 CA488448 
    BM766857 BQ878257 BQ638329 AI288389 BQ213043 BQ183618 BM748663 BM758323 
    AI810761 AI332458 BM770320 AI954579 BC032534 BM850846 AI283487 AK024361 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF703 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF703 Expression
    About this image


    ZNF703 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Heart (Cardiovascular System)
             Endocardial Tube Cells Endocardium
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
    ZNF703 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF703 Protein Expression

    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
    Tissue specificity: Expressed in mammary epithelium

        Custom PCR Arrays for ZNF703
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF703

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZNF703 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp7031 , 5 zinc finger protein 7031, 5 88.83(n)1
    94.9(a)1
      8 (15.91 cM)5
    3533101  NM_001101502.11  NP_001094972.11 
     269773365 
    chicken
    (Gallus gallus)
    Aves ZNF7031 zinc finger protein 703 76.56(n)
    77.29(a)
      770560  XM_001233898.2  XP_001233899.2 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF7036
    zinc finger protein 703
    63(a)
    1 ↔ 1
    GL343406.1(251838-253244)
    African clawed frog
    (Xenopus laevis)
    Amphibia FLJ142992 hypothetical protein FLJ14299 76.77(n)    BC046863.1 
    zebrafish
    (Danio rerio)
    Actinopterygii noz12 nocA related zinc finger 1 76.63(n)   114429  AY026937.1 
    rice
    (Oryza sativa)
    Liliopsida AK066978.12   -- 70.28(n)    AK066978.1 


    ENSEMBL Gene Tree for ZNF703 (if available)
    TreeFam Gene Tree for ZNF703 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF703 gene
    ZNF5032  
    1 SIMAP similar gene for ZNF703 using alignment to 1 protein entry:     ZN703_HUMAN:
    ZNF503

    Find genes that share paralogs with ZNF703           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF703 (see all 86)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69953791,2
    C,F,H--37551354(+) TTTCAC/TAGCCT 1 -- us2k126Minor allele frequency- T:0.07NS EA NA WA CSA 2068
    rs1854542351,2
    --37551660(+) GTCAGC/GGTACC 1 -- us2k10--------
    rs624883591,2
    C,F--37551672(+) CTTTCC/TATTCG 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1897597431,2
    --37551754(+) TATAAA/GTGCTG 1 -- us2k10--------
    rs785084811,2
    C,F--37551767(+) CAAAAT/AACAGT 1 -- us2k12Minor allele frequency- A:0.10CSA WA 120
    rs1146719111,2
    F--37551961(+) GCGGCA/GGAGTC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1131373461,2
    F--37551980(+) GCCATT/CCTAGA 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1383705261,2
    --37552027(+) TGATGA/GATCGG 1 -- us2k10--------
    rs1415833281,2
    --37552075(+) CAGCGC/TGCCTC 1 -- us2k10--------
    rs1872133541,2
    --37552633(+) GACGGG/TCTCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF703 (37553269 - 37557537 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF703:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662845CNV Deletion23128226
    nsv831294CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF703
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF703

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
  • Note=Luminal B breast cancers are the clinically more aggressive estrogen receptor-positive tumors.
    Amplification of a distal 8p12 locus occurs in around one third of the cases and ZNF703 is the single gene within
    the minimal amplicon. Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is
    a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular
    proliferation


  • Find genes that share disorders with ZNF703           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: ZNF703 (1 document)

    Export disorders for ZNF703 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF703 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ZNF703)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization. (PubMed id 21317240)1, 2 Slorach E.M.... Werb Z. (Genes Dev. 2011)
    2. ZNF703 gene amplification at 8p12 specifies luminal B breast cancer. (PubMed id 21328542)1, 2 Sircoulomb F.... Ginestier C. (EMBO Mol. Med. 2011)
    3. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. (PubMed id 21337521)1, 2 Holland D.G.... Caldas C. (EMBO Mol. Med. 2011)
    4. A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. (PubMed id 15897872)1, 3 Garcia M.J....Caldas C. (Oncogene 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Characterization of human NLZ1/ZNF703 identifies conserved domains essential for proper subcellular localization and transcriptional repression. (PubMed id 22886885)1 Pereira-Castro I....da Costa L.T. (J. Cell. Biochem. 2013)
    8. Genetic variants associated with breast size also influence breast cancer risk. (PubMed id 22747683)1 Eriksson N....Tung J.Y. (BMC Med. Genet. 2012)
    9. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (PLoS ONE 2010)
    10. Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis. (PubMed id 19330026)1 Kwek S.S....Albertson D.G. (Oncogene 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80139 HGNC: 25883 AceView: FLJ14299 Ensembl:ENSG00000183779 euGenes: HUgn80139
    ECgene: ZNF703 H-InvDB: ZNF703

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF703 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF703 gene:
    Search GeneIP for patents involving ZNF703

    GeneCards and IP:
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