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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF703 Gene

protein-coding   GIFtS: 50
GCID: GC08P037553

Zinc Finger Protein 703

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 7031 2
Zinc Finger Elbow-Related Proline Domain Protein 12 3
ZEPPO12 3
ZPO12 3
ZNF503L2

External Ids:    HGNC: 258831   Entrez Gene: 801392   Ensembl: ENSG000001837797   UniProtKB: Q9H7S93   

Export aliases for ZNF703 gene to outside databases

Previous GC identifers: GC08P037673 GC08P036088


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF703 Gene: 
ZNF703 (zinc finger protein 703) is a protein-coding gene. Diseases associated with ZNF703 include breast cancer, and among its related super-pathways are Gene Expression. GO annotations related to this gene include repressing transcription factor binding and nucleic acid binding. An important paralog of this gene is ZNF503.

UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
Function: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through
recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May
be required for segmental gene expression during hindbrain development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF703 gene promoter:
         Elk-1   Spz1   LHX3b/Lhx3b   Pax-5   Olf-1   COMP1   FOXO4   LHX3a/Lhx3a   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF703 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF703

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF703


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p11.23   Ensembl cytogenetic band:  8p11.23   HGNC cytogenetic band: 8p12

ZNF703 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF703 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P037553:  view genomic region     (about GC identifiers)

Start:
37,553,269 bp from pter      End:
37,557,537 bp from pter
Size:
4,269 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9 (See protein sequence)
Recommended Name: Zinc finger protein 703  
Size: 590 amino acids; 58222 Da
Subunit: Interacts with TLE4; increases transcriptional repression (By similarity). Interacts with DCAF7 and PHB2.
May interact with HSPD1
Subcellular location: Nucleus. Cytoplasm (By similarity)
Sequence caution: Sequence=AAH84581.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: Q5XG76

Explore the universe of human proteins at neXtProt for ZNF703: NX_Q9H7S9

Explore proteomics data for ZNF703 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H7S9

  • ZNF703 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF703 Protein Expression
    REFSEQ proteins: NP_079345.1  
    ENSEMBL proteins: 
     ENSP00000332325  
    Reactome Protein details: Q9H7S9
    Human Recombinant Protein Products for ZNF703: 
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    OriGene Protein Over-expression Lysate for ZNF703
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF703 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm ISS--

    ZNF703 for ontologies           About GeneDecksing



    ZNF703 Antibody Products: 
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    Assay Products for ZNF703: 
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    Cloud-Clone Corp. ELISAs for ZNF703 
    Cloud-Clone Corp. CLIAs for ZNF703


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR022129 Tscrpt_rep_NocA-like
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9H7S9

    ProtoNet protein and cluster: Q9H7S9

    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
    Similarity: Belongs to the Elbow/Noc family
    Similarity: Contains 1 C2H2-type zinc finger


    ZNF703 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN703_HUMAN, Q9H7S9
    Function: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through
    recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May
    be required for segmental gene expression during hindbrain development
    Induction: Up-regulated by 17-beta-estradiol

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding ----
    GO:0046872metal ion binding IEA--
    GO:0070491repressing transcription factor binding IEA--
         
    ZNF703 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF703:
     Cell cycle / mitosis defect 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF703 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF703

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF703 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF703 

    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF703:
    hsa-miR-569 hsa-miR-3938 hsa-miR-4325 hsa-miR-155 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidZNF703 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF703


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ZNF703 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Generic Transcription Pathway
    Generic Transcription Pathway0.47
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2        Reactome Pathways for ZNF703
        Generic Transcription Pathway
    Gene Expression



    ZNF703 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF703

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ZNF703 (Q9H7S93 ENSP000003323254) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IDA--
    GO:0008284positive regulation of cell proliferation IDA--
    GO:0010718positive regulation of epithelial to mesenchymal transition ISS--
    GO:0017015regulation of transforming growth factor beta receptor signaling pathway IDA--

    ZNF703 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF703 (ZN703)

    Search CenterWatch for drugs/clinical trials and news about ZNF703 / ZN703

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF703 gene: 
    NM_025069.1  

    Unigene Cluster for ZNF703:

    Zinc finger protein 703
    Hs.744591  [show with all ESTs]
    Unigene Representative Sequence: AK024361
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000331569(uc003xjy.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF703
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF703:
    hsa-miR-569 hsa-miR-3938 hsa-miR-4325 hsa-miR-155 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidZNF703 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for ZNF703
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF703
    Clone
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    OriGene clones in human, mouse for ZNF703 (see all 8)
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    GenScript: all cDNA clones in your preferred vector: ZNF703 (NM_025069)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF703
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF703
    Sirion Biotech Customized lentivirus for stable overexpression of ZNF703 
                         Customized lentivirus expression plasmids for stable overexpression of ZNF703 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZNF703
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF703
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF703

    Additional mRNA sequence: 

    AK024361.1 BC032534.1 BC084581.1 

    2 DOTS entries:

    DT.214526  DT.95159844 

    24/139 AceView cDNA sequences (see all 139):

    BM758331 BM820420 BM758889 NM_025069 BM746809 BQ638329 BM770319 BQ183618 
    CK904315 BM772520 AI304422 H49609 AI371143 CA488448 CD671633 BC032534 
    BQ878257 AW204573 BM758591 BM758323 AI332458 BM758052 BM743888 BM758730 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF703 expression in normal human tissues (normalized intensities)      ZNF703 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF703 Expression
    About this image


    ZNF703 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...

    See ZNF703 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF703

    SOURCE GeneReport for Unigene cluster: Hs.744591

    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
    Tissue specificity: Expressed in mammary epithelium

        SABiosciences Custom PCR Arrays for ZNF703
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF703

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZNF703 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp7031 , 5 zinc finger protein 7031, 5 89.57(n)1
    96.09(a)1
      8 (15.91 cM)5
    3533101  NM_001101502.11  NP_001094972.11 
     269773365 
    chicken
    (Gallus gallus)
    Aves ZNF7031 zinc finger protein 703 81.13(n)
    84.56(a)
      770560  XM_001233898.2  XP_001233899.2 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF7036
    Uncharacterized protein
    60(a)
    1 ↔ 1
    GL343406.1(251838-253244)
    African clawed frog
    (Xenopus laevis)
    Amphibia FLJ142992 hypothetical protein FLJ14299 76.77(n)    BC046863.1 
    zebrafish
    (Danio rerio)
    Actinopterygii noz12 nocA related zinc finger 1 76.63(n)   114429  AY026937.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta noc1 no ocelli 46.14(n)
    39.51(a)
      34847  NM_057569.2  NP_476917.1 
    rice
    (Oryza sativa)
    Liliopsida AK066978.12   -- 70.28(n)    AK066978.1 


    ENSEMBL Gene Tree for ZNF703 (if available)
    TreeFam Gene Tree for ZNF703 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF703 gene
    ZNF5032  
    1 SIMAP similar gene for ZNF703 using alignment to 1 protein entry:     ZN703_HUMAN:
    ZNF503

    ZNF703 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/86 SNPs in ZNF703 are shown (see all 86)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69953791,2
    C,F,H--37551354(+) TTTCAC/TAGCCT 1 -- us2k126Minor allele frequency- T:0.07NS EA NA WA CSA 2068
    rs1854542351,2
    --37551660(+) GTCAGC/GGTACC 1 -- us2k10--------
    rs624883591,2
    C,F--37551672(+) CTTTCC/TATTCG 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1897597431,2
    --37551754(+) TATAAA/GTGCTG 1 -- us2k10--------
    rs785084811,2
    C,F--37551767(+) CAAAAT/AACAGT 1 -- us2k12Minor allele frequency- A:0.10CSA WA 120
    rs1146719111,2
    F--37551961(+) GCGGCA/GGAGTC 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1131373461,2
    F--37551980(+) GCCATT/CCTAGA 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1383705261,2
    --37552027(+) TGATGA/GATCGG 1 -- us2k10--------
    rs1415833281,2
    --37552075(+) CAGCGC/TGCCTC 1 -- us2k10--------
    rs1872133541,2
    --37552633(+) GACGGG/TCTCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF703 (37553269 - 37557537 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF703:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2662845CNV Deletion23128226
    nsv831294CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    UniProtKB/Swiss-Prot: ZN703_HUMAN, Q9H7S9
  • Note=Luminal B breast cancers are the clinically more aggressive estrogen receptor-positive tumors.
    Amplification of a distal 8p12 locus occurs in around one third of the cases and ZNF703 is the single gene within
    the minimal amplicon. Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is
    a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular
    proliferation

  • 2 diseases for ZNF703:    About MalaCards
    breast cancer    


    ZNF703 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: ZNF703 (1 document)

    Export disorders for ZNF703 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF703 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ZNF703)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization. (PubMed id 21317240)1, 2 Slorach E.M.... Werb Z. (2011)
    2. ZNF703 gene amplification at 8p12 specifies luminal B breast cancer. (PubMed id 21328542)1, 2 Sircoulomb F.... Ginestier C. (2011)
    3. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. (PubMed id 21337521)1, 2 Holland D.G.... Caldas C. (2011)
    4. A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. (PubMed id 15897872)1, 3 Garcia M.J....Caldas C. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Characterization of human NLZ1/ZNF703 identifies conse rved domains essential for proper subcellular localization and transcriptional r epression. (PubMed id 22886885)1 Pereira-Castro I....da Costa L.T. (2013)
    8. Genetic variants associated with breast size also infl uence breast cancer risk. (PubMed id 22747683)1 Eriksson N....Tung J.Y. (2012)
    9. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
    10. Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis. (PubMed id 19330026)1 Kwek S.S....Albertson D.G. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80139 HGNC: 25883 AceView: FLJ14299 Ensembl:ENSG00000183779 euGenes: HUgn80139
    ECgene: ZNF703 H-InvDB: ZNF703

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF703 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF703 gene:
    Search GeneIP for patents involving ZNF703

    GeneCards and IP:
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