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Aliases for ZNF701 Gene

Aliases for ZNF701 Gene

  • Zinc Finger Protein 701 2 3 5

External Ids for ZNF701 Gene

Previous GeneCards Identifiers for ZNF701 Gene

  • GC19P057766
  • GC19P053073
  • GC19P049404
  • GC19P053059

Summaries for ZNF701 Gene

GeneCards Summary for ZNF701 Gene

ZNF701 (Zinc Finger Protein 701) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF701 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF701 Gene

Genomics for ZNF701 Gene

Regulatory Elements for ZNF701 Gene

Enhancers for ZNF701 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF701 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF701 Gene

52,555,822 bp from pter
52,587,174 bp from pter
31,353 bases
Plus strand

Genomic View for ZNF701 Gene

Genes around ZNF701 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF701 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF701 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF701 Gene

Proteins for ZNF701 Gene

  • Protein details for ZNF701 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 701
    Protein Accession:
    Secondary Accessions:
    • A2RRM8
    • B9EGF2
    • F5GZM6
    • Q66K42

    Protein attributes for ZNF701 Gene

    531 amino acids
    Molecular mass:
    60903 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF701 Gene


neXtProt entry for ZNF701 Gene

Proteomics data for ZNF701 Gene at MOPED

Post-translational modifications for ZNF701 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF701 Gene

No data available for DME Specific Peptides for ZNF701 Gene

Domains & Families for ZNF701 Gene

Gene Families for ZNF701 Gene

Protein Domains for ZNF701 Gene

Suggested Antigen Peptide Sequences for ZNF701 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF701: view

Function for ZNF701 Gene

Molecular function for ZNF701 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF701: view

Animal Model Products

CRISPR Products

miRNA for ZNF701 Gene

miRTarBase miRNAs that target ZNF701

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF701 Gene

Localization for ZNF701 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF701 Gene

Subcellular locations from

Jensen Localization Image for ZNF701 Gene COMPARTMENTS Subcellular localization image for ZNF701 gene
Compartment Confidence
nucleus 5
cytoskeleton 2
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF701 Gene

Pathways & Interactions for ZNF701 Gene

SuperPathways for ZNF701 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF701: view

Pathways by source for ZNF701 Gene

2 Reactome pathways for ZNF701 Gene

Interacting Proteins for ZNF701 Gene

Gene Ontology (GO) - Biological Process for ZNF701 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF701: view

No data available for SIGNOR curated interactions for ZNF701 Gene

Drugs & Compounds for ZNF701 Gene

No Compound Related Data Available

Transcripts for ZNF701 Gene

Unigene Clusters for ZNF701 Gene

Zinc finger protein 701:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF701 Gene

No ASD Table

Relevant External Links for ZNF701 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF701 Gene

mRNA expression in normal human tissues for ZNF701 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF701 Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF701 Gene

SOURCE GeneReport for Unigene cluster for ZNF701 Gene Hs.235167

genes like me logo Genes that share expression patterns with ZNF701: view

Protein tissue co-expression partners for ZNF701 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF701 Gene

Orthologs for ZNF701 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF701 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF701 35
  • 98.57 (n)
  • 97.41 (a)
-- 36
  • 46 (a)
(Bos Taurus)
Mammalia -- 36
  • 32 (a)
(Canis familiaris)
Mammalia -- 36
  • 46 (a)
Species with no ortholog for ZNF701:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF701 Gene

Gene Tree for ZNF701 (if available)
Gene Tree for ZNF701 (if available)

Paralogs for ZNF701 Gene

(525) SIMAP similar genes for ZNF701 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF701: view

Variants for ZNF701 Gene

Sequence variations from dbSNP and Humsavar for ZNF701 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs162832 - 52,574,158(+) TCTTC(C/T)TCAGG reference, missense
rs366793 - 52,582,406(+) AAAAA(C/T)CAAAA reference, missense
rs444172 - 52,583,422(+) TTGAA(C/T)GTCAT reference, missense
rs373554 - 52,582,871(+) TTACA(A/C/G/T)GTGTA reference, missense
rs12462687 - 52,582,414(+) AAAAG(G/T)TGATG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZNF701 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
nsv510772 CNV Loss 20534489
nsv833874 CNV Loss 17160897
nsv458743 CNV Loss 19166990
nsv912304 CNV Loss 21882294
esv2718787 CNV Deletion 23290073
esv2545014 CNV Deletion 19546169
esv2658669 CNV Deletion 23128226
esv2718788 CNV Deletion 23290073
dgv659e199 CNV Deletion 23128226
esv2718789 CNV Deletion 23290073
esv4313 CNV Deletion 18987735
esv2718790 CNV Deletion 23290073
esv2662022 CNV Deletion 23128226

Variation tolerance for ZNF701 Gene

Residual Variation Intolerance Score: 89.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.61; 56.47% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF701 Gene

Disorders for ZNF701 Gene

Relevant External Links for ZNF701

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF701 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF701 Gene

Publications for ZNF701 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF701 Gene

Sources for ZNF701 Gene