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Aliases for ZNF700 Gene

Aliases for ZNF700 Gene

  • Zinc Finger Protein 700 2 3 5

External Ids for ZNF700 Gene

Previous GeneCards Identifiers for ZNF700 Gene

  • GC19P011884
  • GC19P012035
  • GC19P011610

Summaries for ZNF700 Gene

GeneCards Summary for ZNF700 Gene

ZNF700 (Zinc Finger Protein 700) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF700 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF700 Gene

Genomics for ZNF700 Gene

Regulatory Elements for ZNF700 Gene

Promoters for ZNF700 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF700 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF700 Gene

Chromosome:
19
Start:
11,925,068 bp from pter
End:
11,950,773 bp from pter
Size:
25,706 bases
Orientation:
Plus strand

Genomic View for ZNF700 Gene

Genes around ZNF700 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF700 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF700 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF700 Gene

Proteins for ZNF700 Gene

  • Protein details for ZNF700 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0M5-ZN700_HUMAN
    Recommended name:
    Zinc finger protein 700
    Protein Accession:
    Q9H0M5
    Secondary Accessions:
    • B9EGU4

    Protein attributes for ZNF700 Gene

    Size:
    742 amino acids
    Molecular mass:
    86232 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF700 Gene

Proteomics data for ZNF700 Gene at MOPED

Post-translational modifications for ZNF700 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF700 Gene

No data available for DME Specific Peptides for ZNF700 Gene

Domains & Families for ZNF700 Gene

Gene Families for ZNF700 Gene

Protein Domains for ZNF700 Gene

Suggested Antigen Peptide Sequences for ZNF700 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H0M5

UniProtKB/Swiss-Prot:

ZN700_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 18 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 18 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF700: view

Function for ZNF700 Gene

Molecular function for ZNF700 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF700 Gene

GenomeRNAi human phenotypes for ZNF700:
genes like me logo Genes that share phenotypes with ZNF700: view

Animal Model Products

CRISPR Products

miRNA for ZNF700 Gene

miRTarBase miRNAs that target ZNF700

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF700 Gene

Localization for ZNF700 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF700 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF700 Gene COMPARTMENTS Subcellular localization image for ZNF700 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF700 Gene

Pathways & Interactions for ZNF700 Gene

SuperPathways for ZNF700 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF700: view

Pathways by source for ZNF700 Gene

2 Reactome pathways for ZNF700 Gene

Interacting Proteins for ZNF700 Gene

Gene Ontology (GO) - Biological Process for ZNF700 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF700: view

No data available for SIGNOR curated interactions for ZNF700 Gene

Drugs & Compounds for ZNF700 Gene

No Compound Related Data Available

Transcripts for ZNF700 Gene

mRNA/cDNA for ZNF700 Gene

Unigene Clusters for ZNF700 Gene

Zinc finger protein 700:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF700 Gene

No ASD Table

Relevant External Links for ZNF700 Gene

GeneLoc Exon Structure for
ZNF700
ECgene alternative splicing isoforms for
ZNF700

Expression for ZNF700 Gene

mRNA expression in normal human tissues for ZNF700 Gene

Protein differential expression in normal tissues from HIPED for ZNF700 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF700 Gene



SOURCE GeneReport for Unigene cluster for ZNF700 Gene Hs.528486

genes like me logo Genes that share expression patterns with ZNF700: view

Protein tissue co-expression partners for ZNF700 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF700 Gene

Orthologs for ZNF700 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF700 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm19428 35
  • 67.87 (n)
  • 61.77 (a)
Gm7762 16
chimpanzee
(Pan troglodytes)
Mammalia LOC100614631 35
  • 98.37 (n)
  • 97.96 (a)
ZNF700 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102550944 35
  • 67.92 (n)
  • 60.91 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 50 (a)
ManyToMany
Species with no ortholog for ZNF700:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF700 Gene

ENSEMBL:
Gene Tree for ZNF700 (if available)
TreeFam:
Gene Tree for ZNF700 (if available)

Paralogs for ZNF700 Gene

(536) SIMAP similar genes for ZNF700 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF700 Gene

genes like me logo Genes that share paralogs with ZNF700: view

Variants for ZNF700 Gene

Sequence variations from dbSNP and Humsavar for ZNF700 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17001730 - 11,948,985(+) GTTCT(C/G)TTCGT reference, missense
rs12327617 - 11,948,830(+) ACATG(A/G)AAGAA reference, missense
rs371404 -- 11,947,527(+) TGGAG(A/T)GACCA reference, missense
rs376075 -- 11,947,521(+) AAAAA(A/G)TGGAG reference, synonymous-codon
rs445647 -- 11,935,866(+) ctcca(C/G)cccct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF700 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
esv2718185 CNV Deletion 23290073
nsv911069 CNV Loss 21882294
esv2718187 CNV Deletion 23290073
esv2660126 CNV Deletion 23128226
nsv482215 CNV Gain 20164927
nsv2417 CNV Loss 18451855
dgv623e199 CNV Deletion 23128226
esv2718188 CNV Deletion 23290073
esv23756 CNV Loss 19812545
esv2662395 CNV Deletion 23128226
nsv507887 CNV Insertion 20534489
esv2718189 CNV Deletion 23290073

Variation tolerance for ZNF700 Gene

Residual Variation Intolerance Score: 29.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.79; 66.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF700 Gene

HapMap Linkage Disequilibrium report
ZNF700

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF700 Gene

Disorders for ZNF700 Gene

Relevant External Links for ZNF700

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF700

No disorders were found for ZNF700 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF700 Gene

Publications for ZNF700 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF700 Gene

Sources for ZNF700 Gene

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