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Aliases for ZNF7 Gene

Aliases for ZNF7 Gene

  • Zinc Finger Protein 7 2 3 5
  • Zinc Finger Protein 7 (KOX 4, Clone HF.16) 2 3
  • Zinc Finger Protein HF.16 3 4
  • Zinc Finger Protein KOX4 3 4
  • KOX4 3 4
  • C2-H2 Type Zinc Finger Protein 3
  • Zinc Finger Protein-7 (KOX4) 3
  • Zinc Finger Protein Zfp30 3
  • HF.16 3
  • Zf30 3

External Ids for ZNF7 Gene

Previous GeneCards Identifiers for ZNF7 Gene

  • GC08P143660
  • GC08P146090
  • GC08P145633
  • GC08P146057
  • GC08P146023
  • GC08P146052
  • GC08P141168

Summaries for ZNF7 Gene

GeneCards Summary for ZNF7 Gene

ZNF7 (Zinc Finger Protein 7) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF34.

UniProtKB/Swiss-Prot for ZNF7 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF7 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF7 Gene

Genomics for ZNF7 Gene

Regulatory Elements for ZNF7 Gene

Enhancers for ZNF7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF7 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF7 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF7 Gene

144,827,464 bp from pter
144,847,509 bp from pter
20,046 bases
Plus strand

Genomic View for ZNF7 Gene

Genes around ZNF7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF7 Gene

Proteins for ZNF7 Gene

  • Protein details for ZNF7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 7
    Protein Accession:
    Secondary Accessions:
    • B4DT08
    • D3DWN6
    • P17015
    • Q8N8Y4

    Protein attributes for ZNF7 Gene

    686 amino acids
    Molecular mass:
    77887 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF7 Gene


neXtProt entry for ZNF7 Gene

Proteomics data for ZNF7 Gene at MOPED

Post-translational modifications for ZNF7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF7 Gene

Domains & Families for ZNF7 Gene

Gene Families for ZNF7 Gene

Protein Domains for ZNF7 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF7: view

Function for ZNF7 Gene

Molecular function for ZNF7 Gene

GENATLAS Biochemistry:
zinc finger protein 7 (clone ZFP.16,KOX4),Kruppel-like
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF7: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF7 Gene

Localization for ZNF7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF7 Gene

Subcellular locations from

Jensen Localization Image for ZNF7 Gene COMPARTMENTS Subcellular localization image for ZNF7 gene
Compartment Confidence
nucleus 5
mitochondrion 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF7 Gene

Pathways & Interactions for ZNF7 Gene

SuperPathways for ZNF7 Gene

No Data Available

Interacting Proteins for ZNF7 Gene

Selected Interacting proteins: P17097-ZNF7_HUMAN for ZNF7 Gene via I2D

Gene Ontology (GO) - Biological Process for ZNF7 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF7 Gene

Drugs & Compounds for ZNF7 Gene

No Compound Related Data Available

Transcripts for ZNF7 Gene

Unigene Clusters for ZNF7 Gene

Zinc finger protein 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF7 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b
SP1: - - -
SP2: - - - -
SP3: - - -
SP4: - -

Relevant External Links for ZNF7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF7 Gene

mRNA expression in normal human tissues for ZNF7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZNF7 Gene

SOURCE GeneReport for Unigene cluster for ZNF7 Gene Hs.493218

mRNA Expression by UniProt/SwissProt for ZNF7 Gene

Tissue specificity: Ubiquitously present in many human cell lines of different embryological derivation.
genes like me logo Genes that share expression patterns with ZNF7: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Protein tissue co-expression partners for ZNF7 Gene

Orthologs for ZNF7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF7 35
  • 81 (n)
  • 81.85 (a)
ZNF7 36
  • 78 (a)
(Canis familiaris)
Mammalia ZNF7 35
  • 83.5 (n)
  • 83.11 (a)
ZNF7 36
  • 83 (a)
(Mus musculus)
Mammalia Zfp7 35
  • 76.73 (n)
  • 71 (a)
Zfp7 16
Zfp7 36
  • 69 (a)
(Pan troglodytes)
Mammalia ZNF7 35
  • 99.09 (n)
  • 98.99 (a)
ZNF7 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC100910444 35
  • 81.41 (n)
  • 80.36 (a)
(Monodelphis domestica)
Mammalia ZNF7 36
  • 55 (a)
Species with no ortholog for ZNF7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF7 Gene

Gene Tree for ZNF7 (if available)
Gene Tree for ZNF7 (if available)

Paralogs for ZNF7 Gene

(548) SIMAP similar genes for ZNF7 Gene using alignment to 10 proteins: Pseudogenes for ZNF7 Gene

genes like me logo Genes that share paralogs with ZNF7: view

Variants for ZNF7 Gene

Sequence variations from dbSNP and Humsavar for ZNF7 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
VAR_024191 -
VAR_052744 -
VAR_052745 -
rs2103472 -- 144,831,508(-) CCGCG(C/T)CCGGC intron-variant
rs2466402 -- 144,832,152(+) ctcac(A/G)cctgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF7 Gene

Variant ID Type Subtype PubMed ID
nsv891807 CNV Loss 21882294
nsv891897 CNV Loss 21882294
nsv522459 CNV Loss 19592680
nsv891925 CNV Loss 21882294
dgv7985n71 CNV Loss 21882294
nsv891929 CNV Loss 21882294
esv2506190 CNV Deletion 19546169
esv2674326 CNV Deletion 23128226
nsv469809 CNV Loss 16826518

Variation tolerance for ZNF7 Gene

Residual Variation Intolerance Score: 5.52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.31; 26.04% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF7 Gene

Disorders for ZNF7 Gene

Relevant External Links for ZNF7

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF7 Gene

Publications for ZNF7 Gene

  1. cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes. (PMID: 2106481) Lania L. … Pelicci P.-G. (Genomics 1990) 2 3 4 67
  2. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P.L. … Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 1991) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. (PMID: 19795399) Malhotra A. … Hanson R.L. (Diabetes Metab. Res. Rev. 2009) 3

Products for ZNF7 Gene

Sources for ZNF7 Gene