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Aliases for ZNF697 Gene

Aliases for ZNF697 Gene

  • Zinc Finger Protein 697 2 3 5

External Ids for ZNF697 Gene

Previous GeneCards Identifiers for ZNF697 Gene

  • GC01M119877
  • GC01M119963
  • GC01M120162
  • GC01M118020

Summaries for ZNF697 Gene

GeneCards Summary for ZNF697 Gene

ZNF697 (Zinc Finger Protein 697) is a Protein Coding gene. Among its related pathways are Gene Expression.

UniProtKB/Swiss-Prot for ZNF697 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF697 Gene

Genomics for ZNF697 Gene

Regulatory Elements for ZNF697 Gene

Enhancers for ZNF697 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F119672 1.1 Ensembl ENCODE 21.3 -26.3 -26272 3.6 ARID4B RAD21 RFX5 ZNF366 ZNF143 FOS ZNF654 SP3 NFYC CEBPB ZNF697 PHGDH HSD3BP5 LOC105378937
GH01F119613 1 Ensembl ENCODE 20.8 +34.1 34131 0.3 CTCF PKNOX1 ARID4B MAX ZNF48 ZNF2 RAD21 TEAD3 ZBTB48 ZNF366 ZNF697 PHGDH ADAM30 GC01M119620 HSD3BP5
GH01F119723 0.9 ENCODE 20.9 -76.9 -76882 2.3 ELF3 TBP MLX ARID4B ZSCAN9 RAD21 RARA CREM MIXL1 THAP11 PHGDH ZNF697 HMGCS2 LINC00622 LOC105378936 LOC105378937
GH01F119711 1.4 FANTOM5 ENCODE 10.7 -64.9 -64940 3.6 PKNOX1 SIN3A FEZF1 DMAP1 ZNF2 PAF1 ZNF263 SP3 SP5 NFYC PHGDH ADAM30 ZNF697 LOC105378937 LOC105378936
GH01F119686 0.8 Ensembl ENCODE 18.3 -39.1 -39085 1.9 CTBP1 ATF3 CEBPB POU5F1 DPF2 ZNF697 PHGDH LOC105378937
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF697 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF697 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001524098 570 3201 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS ZNF263 SP3 REST

Genomic Location for ZNF697 Gene

Chromosome:
1
Start:
119,619,377 bp from pter
End:
119,648,170 bp from pter
Size:
28,794 bases
Orientation:
Minus strand

Genomic View for ZNF697 Gene

Genes around ZNF697 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF697 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF697 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF697 Gene

Proteins for ZNF697 Gene

  • Protein details for ZNF697 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TEC3-ZN697_HUMAN
    Recommended name:
    Zinc finger protein 697
    Protein Accession:
    Q5TEC3
    Secondary Accessions:
    • Q96IT2

    Protein attributes for ZNF697 Gene

    Size:
    545 amino acids
    Molecular mass:
    60461 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI21950.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZNF697 Gene

Post-translational modifications for ZNF697 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF697 Gene

No data available for DME Specific Peptides for ZNF697 Gene

Domains & Families for ZNF697 Gene

Gene Families for ZNF697 Gene

Protein Domains for ZNF697 Gene

Suggested Antigen Peptide Sequences for ZNF697 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5TEC3

UniProtKB/Swiss-Prot:

ZN697_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF697: view

Function for ZNF697 Gene

Molecular function for ZNF697 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF697 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF697: view

Phenotypes for ZNF697 Gene

GenomeRNAi human phenotypes for ZNF697:
genes like me logo Genes that share phenotypes with ZNF697: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF697 Gene

Localization for ZNF697 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF697 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF697 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF697 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF697: view

Pathways & Interactions for ZNF697 Gene

SuperPathways for ZNF697 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF697: view

Pathways by source for ZNF697 Gene

2 Reactome pathways for ZNF697 Gene

Gene Ontology (GO) - Biological Process for ZNF697 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF697: view

No data available for SIGNOR curated interactions for ZNF697 Gene

Drugs & Compounds for ZNF697 Gene

(2) Drugs for ZNF697 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Interferon beta-1a Approved, Investigational Pharma 198
Interferon beta-1b Approved Pharma 82
genes like me logo Genes that share compounds with ZNF697: view

Transcripts for ZNF697 Gene

mRNA/cDNA for ZNF697 Gene

(4) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF697 Gene

Zinc finger protein 697:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF697 Gene

No ASD Table

Relevant External Links for ZNF697 Gene

GeneLoc Exon Structure for
ZNF697
ECgene alternative splicing isoforms for
ZNF697

Expression for ZNF697 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF697 Gene

Protein differential expression in normal tissues from HIPED for ZNF697 Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF697 Gene



Protein tissue co-expression partners for ZNF697 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF697 Gene:

ZNF697

SOURCE GeneReport for Unigene cluster for ZNF697 Gene:

Hs.381105
genes like me logo Genes that share expression patterns with ZNF697: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF697 Gene

Orthologs for ZNF697 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF697 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF697 34 35
  • 99.63 (n)
cow
(Bos Taurus)
Mammalia ZNF697 34 35
  • 91.16 (n)
dog
(Canis familiaris)
Mammalia ZNF697 34 35
  • 89.73 (n)
mouse
(Mus musculus)
Mammalia Zfp697 34 16 35
  • 87.87 (n)
rat
(Rattus norvegicus)
Mammalia LOC102550892 34
  • 87.38 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF697 35
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF697 35
  • 63 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ZNF697 35
  • 38 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 29 (a)
OneToOne
Species where no ortholog for ZNF697 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF697 Gene

ENSEMBL:
Gene Tree for ZNF697 (if available)
TreeFam:
Gene Tree for ZNF697 (if available)

Paralogs for ZNF697 Gene

(652) SIMAP similar genes for ZNF697 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF697: view

No data available for Paralogs for ZNF697 Gene

Variants for ZNF697 Gene

Sequence variations from dbSNP and Humsavar for ZNF697 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1045827 -- 119,619,819(+) TTAAA(C/T)TGCTC utr-variant-3-prime
rs1045840 -- 119,619,477(-) GCATT(C/T)TGGTG utr-variant-3-prime
rs10494228 -- 119,635,202(+) GTTTT(C/G/T)GCCAG intron-variant
rs10737756 -- 119,620,624(+) GAAAA(C/T)GAGAA utr-variant-3-prime
rs10754415 -- 119,620,625(+) AAAAT(A/G)AGAAT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF697 Gene

Variant ID Type Subtype PubMed ID
nsv547621 CNV loss 21841781
nsv524681 CNV gain 19592680
nsv508034 OTHER sequence alteration 20534489
nsv463317 CNV gain 19166990
esv2758964 CNV gain+loss 17122850
esv2671484 CNV deletion 23128226
dgv525n54 CNV loss 21841781
dgv524n54 CNV gain 21841781

Variation tolerance for ZNF697 Gene

Gene Damage Index Score: 2.32; 41.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF697 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF697

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF697 Gene

Disorders for ZNF697 Gene

Relevant External Links for ZNF697

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF697

No disorders were found for ZNF697 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF697 Gene

Publications for ZNF697 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  2. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3 64
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF697 Gene

Sources for ZNF697 Gene

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