ZNF696 Gene
protein-coding GIFtS: 45
GCID: GC08P144373
|
|
zinc finger protein 696
| |
Aliases
for ZNF696 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6961 2 | | FLJ141291 |
Export aliases for ZNF696 gene to outside databasesPrevious GC identifers: GC08P144445 GC08P144446 GC08P139627 |
Summaries
for ZNF696 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN696_HUMAN, Q9H7X3Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF696 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF696 gene promoter:
Bach2 AP-4 NF-E2 p45 NF-E2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF696
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF696 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3ZNF696 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P144373: view genomic region
(about GC identifiers)
Start:
|
144,371,846 bp from pter |
End:
|
144,382,122 bp from pter |
Size:
|
10,277 bases |
Orientation:
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plus strand |
|
Proteins
for ZNF696 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN696_HUMAN, Q9H7X3 (See
protein sequence)Recommended Name: Zinc finger protein 696 Size: 374 amino acids; 40575 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A0AVE2Explore the universe of human proteins at neXtProt for ZNF696: NX_Q9H7X3
ZNF696 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112157.2
ENSEMBL proteins: ENSP00000428163 ENSP00000427857 ENSP00000328515 ENSP00000429859 ENSP00000428856 ENSP00000430952 Reactome Protein details: Q9H7X3
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF696 for ontologies About GeneDecksing
ZNF696 Antibody Products:
Assay Products for ZNF696: |
Protein
Domains /
Families
for ZNF696 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF696 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H7X3ProtoNet protein and cluster: Q9H7X3 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN696_HUMAN, Q9H7X3Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 9 C2H2-type zinc fingers |
Function
for ZNF696 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN696_HUMAN, Q9H7X3Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF696 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF696 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF696 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF696 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF696 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF696
ZNF696 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF696
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF696 (ENSP000003285154) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF696 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF696 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF696
Search CenterWatch for drugs/clinical trials and news about ZNF696 / ZN696
|
Transcripts
for ZNF696 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF696 gene: NM_030895.2 Unigene Cluster for ZNF696: Zinc finger protein 696 Hs.512740 [show with all ESTs]Unigene Representative Sequence: NM_0308956 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523891 ENST00000518575 ENST00000330143(uc003yxy.4) ENST00000521537
ENST00000518432 ENST00000520333
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF696 (NM_030895) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF696 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF696 |
Additional cDNA sequence: AK024191.1 BC126317.1 4 DOTS entries: DT.40270386 DT.95256483 DT.444665 DT.95331494 24/36 AceView cDNA sequences (see all 36): NM_030895 AI278460 BF510457 AI273629 BQ898243 BE220484 AK024191 AA357173 AI953671 BI916005 AI268981 CD674916 BX375245 BQ052481 BX390342 CD701748 AU122554 BX378282 BM504986 AI298974 AI452697 BM504664 BX282580 CF146234
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF696 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF696
|
Expression
for ZNF696 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF696 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAATTAGAA
About this image
See ZNF696 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF696
SOURCE GeneReport for Unigene cluster: Hs.512740
SABiosciences Custom PCR Arrays for ZNF696
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF696
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF696 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF696 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF696 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF696 |
Orthologs
for ZNF696 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF696 gene from 1/4 species (see all 4) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
CF591461.12 |
-- |
74(n) |
|
CF591461.1 |
Species with no ortholog for ZNF696
ENSEMBL Gene Tree for ZNF696 (if available)
TreeFam Gene Tree for ZNF696 (if available) |
Paralogs
for ZNF696 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF696 gene
- GLI42
18/539 SIMAP similar genes for ZNF696 using alignment to 6 protein entries: ZN696_HUMAN (see all proteins)
(see all similar genes):HZF36 ZFP41 ZNF418 DKFZp547L155 ZNF16 ZNF78L1
ZNF22 ZNF211 DKFZp571N1833 DKFZp686H20223 ZNF132 ZNF133
ZNF23 ZNF551 ZNF283 ZNF544 ZFP3 ZNF154
ZNF696 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF696 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF696 (144371846 - 144382122 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF696
2 CNVs: 7673 30299 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF696 |
|
Disorders
/ Diseases
for ZNF696 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF696 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF696 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF696) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)
|
External Searches for ZNF696 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF696 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF696 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF696 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF696 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF696 gene:
Search GeneIP for patents involving ZNF696
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF696 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF696 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF696 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF696 | | | OriGene Protein Over-expression Lysate for ZNF696 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF696 | | OriGene 3'-UTR Clone for ZNF696 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF696 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF696 | | OriGene Custom Protein Services for ZNF696 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF696 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF696 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF696 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF696 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF696 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF696 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF696 |
| |  |  |  |  | | | | |
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 |
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 | | | ZNF696 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF696 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF696 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF696 |
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