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Aliases for ZNF696 Gene

Aliases for ZNF696 Gene

  • Zinc Finger Protein 696 2 3 5

External Ids for ZNF696 Gene

Previous GeneCards Identifiers for ZNF696 Gene

  • GC08P144445
  • GC08P144446
  • GC08P144373
  • GC08P139627

Summaries for ZNF696 Gene

GeneCards Summary for ZNF696 Gene

ZNF696 (Zinc Finger Protein 696) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF70.

UniProtKB/Swiss-Prot for ZNF696 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF696 Gene

Genomics for ZNF696 Gene

Regulatory Elements for ZNF696 Gene

Promoters for ZNF696 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF696 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF696 Gene

Chromosome:
8
Start:
143,289,676 bp from pter
End:
143,299,952 bp from pter
Size:
10,277 bases
Orientation:
Plus strand

Genomic View for ZNF696 Gene

Genes around ZNF696 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF696 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF696 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF696 Gene

Proteins for ZNF696 Gene

  • Protein details for ZNF696 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7X3-ZN696_HUMAN
    Recommended name:
    Zinc finger protein 696
    Protein Accession:
    Q9H7X3
    Secondary Accessions:
    • A0AVE2

    Protein attributes for ZNF696 Gene

    Size:
    374 amino acids
    Molecular mass:
    40575 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF696 Gene

Proteomics data for ZNF696 Gene at MOPED

Post-translational modifications for ZNF696 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF696 Gene

No data available for DME Specific Peptides for ZNF696 Gene

Domains & Families for ZNF696 Gene

Gene Families for ZNF696 Gene

Protein Domains for ZNF696 Gene

Suggested Antigen Peptide Sequences for ZNF696 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H7X3

UniProtKB/Swiss-Prot:

ZN696_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF696: view

Function for ZNF696 Gene

Molecular function for ZNF696 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF696: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF696 Gene

Localization for ZNF696 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF696 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF696 Gene COMPARTMENTS Subcellular localization image for ZNF696 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF696 Gene

Pathways & Interactions for ZNF696 Gene

SuperPathways for ZNF696 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF696: view

Pathways by source for ZNF696 Gene

2 Reactome pathways for ZNF696 Gene

Interacting Proteins for ZNF696 Gene

Gene Ontology (GO) - Biological Process for ZNF696 Gene

None

No data available for SIGNOR curated interactions for ZNF696 Gene

Drugs & Compounds for ZNF696 Gene

No Compound Related Data Available

Transcripts for ZNF696 Gene

Unigene Clusters for ZNF696 Gene

Zinc finger protein 696:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF696 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d
SP1: - - - - - - - -
SP2: - -
SP3: - - -
SP4: - - - -
SP5:
SP6: -

Relevant External Links for ZNF696 Gene

GeneLoc Exon Structure for
ZNF696
ECgene alternative splicing isoforms for
ZNF696

Expression for ZNF696 Gene

mRNA expression in normal human tissues for ZNF696 Gene

Protein differential expression in normal tissues from HIPED for ZNF696 Gene

This gene is overexpressed in Cerebrospinal fluid (58.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF696 Gene



SOURCE GeneReport for Unigene cluster for ZNF696 Gene Hs.512740

genes like me logo Genes that share expression patterns with ZNF696: view

Protein tissue co-expression partners for ZNF696 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF696 Gene

Orthologs for ZNF696 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF696 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF696 35
  • 99.11 (n)
  • 98.13 (a)
ZNF696 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC511669 35
  • 72.34 (n)
  • 67.03 (a)
dog
(Canis familiaris)
Mammalia ZNF696 35
  • 75.05 (n)
  • 69.49 (a)
ZNF696 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 9130023H24Rik 36
  • 38 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF696 36
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 36 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 25 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
Species with no ortholog for ZNF696:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF696 Gene

ENSEMBL:
Gene Tree for ZNF696 (if available)
TreeFam:
Gene Tree for ZNF696 (if available)

Paralogs for ZNF696 Gene

(542) SIMAP similar genes for ZNF696 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF696: view

Variants for ZNF696 Gene

Sequence variations from dbSNP and Humsavar for ZNF696 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs2235115 -- 143,296,014(+) CCCGG(C/G/T)GCAGA reference, synonymous-codon
rs3889655 -- 143,294,426(+) CTGTC(A/G)CCAGG intron-variant
rs3750217 -- 143,297,082(+) CTCCC(A/C)GCCTC utr-variant-3-prime
rs4354320 -- 143,294,084(+) AGCGG(C/T)CCCCC intron-variant
rs4493919 -- 143,291,322(+) AGCGC(A/G)CTGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF696 Gene

Variant ID Type Subtype PubMed ID
dgv7920n71 CNV Loss 21882294
dgv7921n71 CNV Loss 21882294
dgv7922n71 CNV Loss 21882294
dgv7923n71 CNV Loss 21882294
nsv891669 CNV Loss 21882294
nsv891671 CNV Loss 21882294
nsv470247 CNV Loss 18288195
nsv891673 CNV Loss 21882294
nsv891674 CNV Loss 21882294
esv33151 CNV Gain 17666407

Variation tolerance for ZNF696 Gene

Residual Variation Intolerance Score: 71.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.97; 19.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF696 Gene

HapMap Linkage Disequilibrium report
ZNF696

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF696 Gene

Disorders for ZNF696 Gene

Relevant External Links for ZNF696

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF696

No disorders were found for ZNF696 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF696 Gene

Publications for ZNF696 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for ZNF696 Gene

Sources for ZNF696 Gene

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