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Aliases for ZNF695 Gene

Aliases for ZNF695 Gene

  • Zinc Finger Protein 695 2 3 5
  • Zinc Finger Protein SBZF3 3 4
  • SBZF3 3

External Ids for ZNF695 Gene

Previous GeneCards Identifiers for ZNF695 Gene

  • GC01M243435
  • GC01M245175
  • GC01M247109
  • GC01M217542
  • GC01M247113

Summaries for ZNF695 Gene

GeneCards Summary for ZNF695 Gene

ZNF695 (Zinc Finger Protein 695) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF98.

UniProtKB/Swiss-Prot for ZNF695 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF695 Gene

Genomics for ZNF695 Gene

Regulatory Elements for ZNF695 Gene

Enhancers for ZNF695 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF695 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF695 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF695 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF695 Gene

Chromosome:
1
Start:
246,945,547 bp from pter
End:
247,008,093 bp from pter
Size:
62,547 bases
Orientation:
Minus strand

Genomic View for ZNF695 Gene

Genes around ZNF695 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF695 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF695 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF695 Gene

Proteins for ZNF695 Gene

  • Protein details for ZNF695 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IW36-ZN695_HUMAN
    Recommended name:
    Zinc finger protein 695
    Protein Accession:
    Q8IW36
    Secondary Accessions:
    • Q5T0N9
    • Q5T0P1
    • Q5T0P3
    • Q7Z2W8
    • Q7Z648

    Protein attributes for ZNF695 Gene

    Size:
    515 amino acids
    Molecular mass:
    60149 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF695 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF695 Gene

Post-translational modifications for ZNF695 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF695 Gene

No data available for DME Specific Peptides for ZNF695 Gene

Domains & Families for ZNF695 Gene

Gene Families for ZNF695 Gene

Protein Domains for ZNF695 Gene

Suggested Antigen Peptide Sequences for ZNF695 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IW36

UniProtKB/Swiss-Prot:

ZN695_HUMAN :
  • Contains 1 KRAB domain.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF695: view

Function for ZNF695 Gene

Molecular function for ZNF695 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF695 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF695: view

Phenotypes for ZNF695 Gene

genes like me logo Genes that share phenotypes with ZNF695: view

Animal Model Products

CRISPR Products

miRNA for ZNF695 Gene

miRTarBase miRNAs that target ZNF695

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF695 Gene

Localization for ZNF695 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF695 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF695 Gene COMPARTMENTS Subcellular localization image for ZNF695 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF695 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF695: view

Pathways & Interactions for ZNF695 Gene

SuperPathways for ZNF695 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF695 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF695: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF695 Gene

Drugs & Compounds for ZNF695 Gene

No Compound Related Data Available

Transcripts for ZNF695 Gene

Unigene Clusters for ZNF695 Gene

Zinc finger protein 695:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF695 Gene

No ASD Table

Relevant External Links for ZNF695 Gene

GeneLoc Exon Structure for
ZNF695
ECgene alternative splicing isoforms for
ZNF695

Expression for ZNF695 Gene

mRNA expression in normal human tissues for ZNF695 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF695 Gene

This gene is overexpressed in Testis (x10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF695 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF695 Gene:

ZNF695

SOURCE GeneReport for Unigene cluster for ZNF695 Gene:

Hs.669893
genes like me logo Genes that share expression patterns with ZNF695: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF695 Gene

Orthologs for ZNF695 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF695 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF695 34
  • 99.22 (n)
  • 98.45 (a)
ZNF695 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 47 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 34 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 33 (a)
ManyToMany
-- 35
  • 51 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia ZFP953 35
  • 54 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 47 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
-- 35
  • 27 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 25 (a)
ManyToMany
Species where no ortholog for ZNF695 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF695 Gene

ENSEMBL:
Gene Tree for ZNF695 (if available)
TreeFam:
Gene Tree for ZNF695 (if available)

Paralogs for ZNF695 Gene

(506) SIMAP similar genes for ZNF695 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF695: view

Variants for ZNF695 Gene

Sequence variations from dbSNP and Humsavar for ZNF695 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_057446 -
VAR_057447 -
VAR_061963 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF695 Gene

Variant ID Type Subtype PubMed ID
esv2668869 CNV deletion 23128226
esv33129 CNV gain+loss 17666407
esv3589499 CNV loss 21293372
esv3589500 CNV loss 21293372
esv3891381 CNV loss 25118596
nsv1141906 OTHER inversion 24896259
nsv524007 CNV gain 19592680
nsv549546 CNV loss 21841781
nsv945436 CNV duplication 23825009
nsv999879 CNV gain 25217958

Variation tolerance for ZNF695 Gene

Residual Variation Intolerance Score: 85.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.18; 61.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF695 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF695

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF695 Gene

Disorders for ZNF695 Gene

Relevant External Links for ZNF695

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF695

No disorders were found for ZNF695 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF695 Gene

Publications for ZNF695 Gene

  1. Splice variants of zinc finger protein 695 mRNA associated to ovarian cancer. (PMID: 24007497) JuA!rez-MAcndez S. … Moreno J. (J Ovarian Res 2013) 2 3 65
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. ZNF695 methylation predicts a response of esophageal squamous cell carcinoma to definitive chemoradiotherapy. (PMID: 25273507) Takahashi T. … Ushijima T. (J. Cancer Res. Clin. Oncol. 2015) 3 65
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65

Products for ZNF695 Gene

Sources for ZNF695 Gene

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