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Aliases for ZNF692 Gene

Aliases for ZNF692 Gene

  • Zinc Finger Protein 692 2 3 5
  • AICAR Responsive Element Binding Protein 2 3
  • Zfp692 3
  • AREBP 3

External Ids for ZNF692 Gene

Previous GeneCards Identifiers for ZNF692 Gene

  • GC01M245354
  • GC01M247110
  • GC01M249144
  • GC01M219385

Summaries for ZNF692 Gene

GeneCards Summary for ZNF692 Gene

ZNF692 (Zinc Finger Protein 692) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZFP91-CNTF.

UniProtKB/Swiss-Prot for ZNF692 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF692 Gene

Genomics for ZNF692 Gene

Regulatory Elements for ZNF692 Gene

Enhancers for ZNF692 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G248820 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +35.9 35859 9.8 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SH3BP5L ENSG00000227237 ZNF692 PGBD2 RNU6-1205P RPL23AP25 MIR3124 GC01P248810
GH01G248924 1.2 Ensembl ENCODE 11.3 -65.1 -65148 2.5 HDGF PKNOX1 ATF1 ARNT RAD21 RFX5 TCF12 ZNF143 IKZF2 CREM ZNF672 ENSG00000227237 ZNF692 PGBD2 SH3BP5L PIR45582 GC01P248921 PIR40629
GH01G248857 1.3 ENCODE dbSUPER 8.1 +1.9 1920 3.6 HDGF PKNOX1 MLX CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF766 ZNF692 ENSG00000227237 PIR53527
GH01G248886 0.8 Ensembl dbSUPER 11.5 -25.9 -25903 0.2 NFIC PBX2 IKZF1 ZNF592 RNU6-1205P ZNF672 ENSG00000227237 ZNF692 SH3BP5L PIR34959 TRE-CTC2-1
GH01G248840 1.3 Ensembl ENCODE dbSUPER 6.8 +18.6 18566 3.7 TBP CTCF USF1 MXI1 BACH1 EBF1 RAD21 POLR2A HNF4G ZNF143 SH3BP5L ZNF692 ZNF672 PIR53527
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF692 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF692 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000023271 1998 1601 HDGF PKNOX1 MLX CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF766

Genomic Location for ZNF692 Gene

Chromosome:
1
Start:
248,850,004 bp from pter
End:
248,860,798 bp from pter
Size:
10,795 bases
Orientation:
Minus strand

Genomic View for ZNF692 Gene

Genes around ZNF692 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF692 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF692 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF692 Gene

Proteins for ZNF692 Gene

  • Protein details for ZNF692 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BU19-ZN692_HUMAN
    Recommended name:
    Zinc finger protein 692
    Protein Accession:
    Q9BU19
    Secondary Accessions:
    • B4DXZ0
    • Q5SRA5
    • Q5SRA6
    • Q9HBC9
    • Q9NW93
    • Q9NWY6
    • Q9UF97

    Protein attributes for ZNF692 Gene

    Size:
    519 amino acids
    Molecular mass:
    56968 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF692 Gene

    Alternative splice isoforms for ZNF692 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF692 Gene

Post-translational modifications for ZNF692 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF692 Gene

Domains & Families for ZNF692 Gene

Gene Families for ZNF692 Gene

Protein Domains for ZNF692 Gene

Suggested Antigen Peptide Sequences for ZNF692 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BU19

UniProtKB/Swiss-Prot:

ZN692_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF692: view

Function for ZNF692 Gene

Molecular function for ZNF692 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF692 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF692: view
genes like me logo Genes that share phenotypes with ZNF692: view

Animal Model Products

CRISPR Products

Targeted motifs for ZNF692 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF692
  • Consensus sequence: GTGGGCCCCA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA and Transcription Factor Targets for ZNF692 Gene

Localization for ZNF692 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF692 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF692 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF692 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with ZNF692: view

Pathways & Interactions for ZNF692 Gene

SuperPathways for ZNF692 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF692: view

Pathways by source for ZNF692 Gene

2 Reactome pathways for ZNF692 Gene

Interacting Proteins for ZNF692 Gene

SIGNOR curated interactions for ZNF692 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for ZNF692 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF692: view

Drugs & Compounds for ZNF692 Gene

No Compound Related Data Available

Transcripts for ZNF692 Gene

Unigene Clusters for ZNF692 Gene

Zinc finger protein 692:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF692 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e · 5f · 5g · 5h · 5i ^ 6a · 6b · 6c ·
SP1: - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - -
SP4:
SP5: - - - - - - - - - - - - - - -
SP6: - - - - - - - - -
SP7:
SP8:
SP9:
SP10: - - - - - - - - -
SP11: - - - -
SP12:
SP13: - - - - - - - - - - - - - - -
SP14: - - - - - - -
SP15: - - - - - - - -
SP16: - - - - - - - - - - - - - - - -
SP17: - - - - - - - - - - - - - - - -
SP18: - - - - - - - - -
SP19: - - - - - - - - - - - - -
SP20: - - - - - - - - - - - -
SP21: - - - -
SP22:
SP23:
SP24:
SP25:
SP26: - - - - - -
SP27: - - - - -
SP28: - - -
SP29: - - - -
SP30: - -
SP31:

ExUns: 6d · 6e · 6f · 6g ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c · 12d · 12e ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18a ·
SP1: - - - - - - - - -
SP2: - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - -
SP4: - -
SP5: - - - - - - - - -
SP6: - - - - -
SP7: - -
SP8: - - - - - - - -
SP9: - - -
SP10: - - - - -
SP11: - - - - -
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: - - - - - - - -
SP22: - - - -
SP23: - -
SP24: -
SP25: -
SP26:
SP27:
SP28:
SP29:
SP30:
SP31: - - - - -

Relevant External Links for ZNF692 Gene

GeneLoc Exon Structure for
ZNF692
ECgene alternative splicing isoforms for
ZNF692

Expression for ZNF692 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF692 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF692 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF692 Gene



Protein tissue co-expression partners for ZNF692 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF692 Gene:

ZNF692

SOURCE GeneReport for Unigene cluster for ZNF692 Gene:

Hs.377705

Evidence on tissue expression from TISSUES for ZNF692 Gene

  • Nervous system(4.5)
  • Lung(4.3)
genes like me logo Genes that share expression patterns with ZNF692: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF692 Gene

Orthologs for ZNF692 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF692 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF692 34 35
  • 99.74 (n)
dog
(Canis familiaris)
Mammalia ZNF692 34 35
  • 86.42 (n)
cow
(Bos Taurus)
Mammalia ZNF692 34 35
  • 85.42 (n)
rat
(Rattus norvegicus)
Mammalia Zfp692 34
  • 84.93 (n)
mouse
(Mus musculus)
Mammalia Zfp692 34 16 35
  • 80.04 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF692 35
  • 66 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF692 35
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF692 35
  • 43 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf692 34 35
  • 59.39 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 17 (a)
OneToMany
Species where no ortholog for ZNF692 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF692 Gene

ENSEMBL:
Gene Tree for ZNF692 (if available)
TreeFam:
Gene Tree for ZNF692 (if available)

Paralogs for ZNF692 Gene

Paralogs for ZNF692 Gene

genes like me logo Genes that share paralogs with ZNF692: view

Variants for ZNF692 Gene

Sequence variations from dbSNP and Humsavar for ZNF692 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000226515 -- 248,852,938(+) TTTTT(A/G)CCTGA intron-variant
rs1000342818 -- 248,858,991(+) CCCGG(A/T)GCTGC intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime
rs1000451652 -- 248,851,928(+) CTTCC(A/C)CGCTC intron-variant
rs1000855712 -- 248,858,883(+) CCAGA(A/G)CCCCC intron-variant, utr-variant-5-prime
rs1001869251 -- 248,862,595(+) TCTTC(C/T)CTCCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF692 Gene

Variant ID Type Subtype PubMed ID
dgv631n100 CNV gain 25217958
dgv644n100 CNV gain 25217958
esv21433 CNV loss 19812545
esv2750832 CNV gain 17911159
esv2750835 CNV gain 17911159
esv3575994 CNV gain 25503493
esv3589576 CNV gain 21293372
esv3589577 CNV gain 21293372
nsv5398 CNV insertion 18451855
nsv549745 CNV loss 21841781
nsv999043 CNV gain 25217958

Variation tolerance for ZNF692 Gene

Residual Variation Intolerance Score: 37.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.57; 72.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF692 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF692

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF692 Gene

Disorders for ZNF692 Gene

Relevant External Links for ZNF692

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF692

No disorders were found for ZNF692 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF692 Gene

Publications for ZNF692 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. AMP-activated protein kinase regulates PEPCK gene expression by direct phosphorylation of a novel zinc finger transcription factor. (PMID: 17097062) Inoue E. … Yamauchi J. (Biochem. Biophys. Res. Commun. 2006) 2 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64

Products for ZNF692 Gene

Sources for ZNF692 Gene

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