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Aliases for ZNF692 Gene

Aliases for ZNF692 Gene

  • Zinc Finger Protein 692 2 3 5
  • AICAR Responsive Element Binding Protein 2 3
  • Zfp692 3
  • AREBP 3

External Ids for ZNF692 Gene

Previous GeneCards Identifiers for ZNF692 Gene

  • GC01M245354
  • GC01M247110
  • GC01M249144
  • GC01M219385

Summaries for ZNF692 Gene

GeneCards Summary for ZNF692 Gene

ZNF692 (Zinc Finger Protein 692) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZFP91.

UniProtKB/Swiss-Prot for ZNF692 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF692 Gene

Genomics for ZNF692 Gene

Regulatory Elements for ZNF692 Gene

Genomic Location for ZNF692 Gene

Chromosome:
1
Start:
248,850,004 bp from pter
End:
248,860,798 bp from pter
Size:
10,795 bases
Orientation:
Minus strand

Genomic View for ZNF692 Gene

Genes around ZNF692 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF692 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF692 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF692 Gene

Proteins for ZNF692 Gene

  • Protein details for ZNF692 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BU19-ZN692_HUMAN
    Recommended name:
    Zinc finger protein 692
    Protein Accession:
    Q9BU19
    Secondary Accessions:
    • B4DXZ0
    • Q5SRA5
    • Q5SRA6
    • Q9HBC9
    • Q9NW93
    • Q9NWY6
    • Q9UF97

    Protein attributes for ZNF692 Gene

    Size:
    519 amino acids
    Molecular mass:
    56968 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF692 Gene

    Alternative splice isoforms for ZNF692 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF692 Gene

Proteomics data for ZNF692 Gene at MOPED

Post-translational modifications for ZNF692 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF692 Gene

Domains & Families for ZNF692 Gene

Gene Families for ZNF692 Gene

Protein Domains for ZNF692 Gene

Suggested Antigen Peptide Sequences for ZNF692 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BU19

UniProtKB/Swiss-Prot:

ZN692_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 5 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF692: view

Function for ZNF692 Gene

Molecular function for ZNF692 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF692: view

Animal Model Products

CRISPR Products

Targeted motifs for ZNF692 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF692
  • Consensus sequence: GTGGGCCCCA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA and Transcription Factor Targets for ZNF692 Gene

Localization for ZNF692 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF692 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF692 Gene COMPARTMENTS Subcellular localization image for ZNF692 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF692 Gene

Pathways & Interactions for ZNF692 Gene

SuperPathways for ZNF692 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF692: view

Pathways by source for ZNF692 Gene

2 Reactome pathways for ZNF692 Gene

Interacting Proteins for ZNF692 Gene

SIGNOR curated interactions for ZNF692 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for ZNF692 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF692: view

Drugs & Compounds for ZNF692 Gene

No Compound Related Data Available

Transcripts for ZNF692 Gene

Unigene Clusters for ZNF692 Gene

Zinc finger protein 692:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF692 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e · 5f · 5g · 5h · 5i ^ 6a · 6b · 6c ·
SP1: - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - -
SP4:
SP5: - - - - - - - - - - - - - - -
SP6: - - - - - - - - -
SP7:
SP8:
SP9:
SP10: - - - - - - - - -
SP11: - - - -
SP12:
SP13: - - - - - - - - - - - - - - -
SP14: - - - - - - -
SP15: - - - - - - - -
SP16: - - - - - - - - - - - - - - - -
SP17: - - - - - - - - - - - - - - - -
SP18: - - - - - - - - -
SP19: - - - - - - - - - - - - -
SP20: - - - - - - - - - - - -
SP21: - - - -
SP22:
SP23:
SP24:
SP25:
SP26: - - - - - -
SP27: - - - - -
SP28: - - -
SP29: - - - -
SP30: - -
SP31:

ExUns: 6d · 6e · 6f · 6g ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c · 12d · 12e ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18a ·
SP1: - - - - - - - - -
SP2: - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - -
SP4: - -
SP5: - - - - - - - - -
SP6: - - - - -
SP7: - -
SP8: - - - - - - - -
SP9: - - -
SP10: - - - - -
SP11: - - - - -
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: - - - - - - - -
SP22: - - - -
SP23: - -
SP24: -
SP25: -
SP26:
SP27:
SP28:
SP29:
SP30:
SP31: - - - - -

Relevant External Links for ZNF692 Gene

GeneLoc Exon Structure for
ZNF692
ECgene alternative splicing isoforms for
ZNF692

Expression for ZNF692 Gene

mRNA expression in normal human tissues for ZNF692 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF692 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF692 Gene



SOURCE GeneReport for Unigene cluster for ZNF692 Gene Hs.377705

genes like me logo Genes that share expression patterns with ZNF692: view

Protein tissue co-expression partners for ZNF692 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF692 Gene

Orthologs for ZNF692 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF692 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF692 36
  • 100 (a)
OneToOne
ZNF692 35
  • 99.74 (n)
  • 99.81 (a)
cow
(Bos Taurus)
Mammalia ZNF692 35
  • 85.42 (n)
  • 83.53 (a)
ZNF692 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF692 36
  • 81 (a)
OneToOne
ZNF692 35
  • 86.42 (n)
  • 85.16 (a)
mouse
(Mus musculus)
Mammalia Zfp692 16
Zfp692 36
  • 75 (a)
OneToOne
Zfp692 35
  • 80.04 (n)
  • 77.45 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF692 36
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp692 35
  • 84.93 (n)
  • 85.65 (a)
chicken
(Gallus gallus)
Aves ZNF692 36
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF692 36
  • 43 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf692 36
  • 40 (a)
OneToOne
znf692 35
  • 59.39 (n)
  • 56.05 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 17 (a)
OneToMany
Species with no ortholog for ZNF692:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF692 Gene

ENSEMBL:
Gene Tree for ZNF692 (if available)
TreeFam:
Gene Tree for ZNF692 (if available)

Paralogs for ZNF692 Gene

Paralogs for ZNF692 Gene

genes like me logo Genes that share paralogs with ZNF692: view

Variants for ZNF692 Gene

Sequence variations from dbSNP and Humsavar for ZNF692 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs13313088 - 248,855,917(+) GGGAA(C/G)GCAGT nc-transcript-variant, downstream-variant-500B, reference, missense
rs6656768 -- 248,851,429(+) CTGCT(A/G)TGGTT intron-variant
rs11205429 -- 248,852,087(+) CTGTA(A/G)GGGCA intron-variant
rs12135449 -- 248,855,287(+) CTGAA(C/T)CCTCC intron-variant
rs12080783 -- 248,853,661(+) CTGTA(A/T)CACTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF692 Gene

Variant ID Type Subtype PubMed ID
esv2750832 CNV Gain 17911159
esv2750835 CNV Gain 17911159
nsv5398 CNV Insertion 18451855
esv21433 CNV Loss 19812545

Variation tolerance for ZNF692 Gene

Residual Variation Intolerance Score: 37.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.57; 72.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF692 Gene

HapMap Linkage Disequilibrium report
ZNF692

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF692 Gene

Disorders for ZNF692 Gene

Relevant External Links for ZNF692

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF692

No disorders were found for ZNF692 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF692 Gene

Publications for ZNF692 Gene

  1. AMP-activated protein kinase regulates PEPCK gene expression by direct phosphorylation of a novel zinc finger transcription factor. (PMID: 17097062) Inoue E. … Yamauchi J. (Biochem. Biophys. Res. Commun. 2006) 2 3 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for ZNF692 Gene

Sources for ZNF692 Gene

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