ZNF691 Gene
protein-coding GIFtS: 46
GCID: GC01P043312
|
|
zinc finger protein 691
| |
Aliases
for ZNF691 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6911 2 | | Zfp6911 2 |
Export aliases for ZNF691 gene to outside databasesPrevious GC identifers: GC01P042982 GC01P043085 GC01P041432 |
Summaries
for ZNF691 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN691_HUMAN, Q5VV52Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF691 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF691 gene promoter:
ISGF-3 FOXC1 AML1a Zic1 CUTL1 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF691
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF691 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p34.2 Ensembl cytogenetic band: 1p34.2 HGNC cytogenetic band: 1p34.2ZNF691 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P043312: view genomic region
(about GC identifiers)
Start:
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43,312,280 bp from pter |
End:
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43,318,148 bp from pter |
Size:
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5,869 bases |
Orientation:
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plus strand |
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Proteins
for ZNF691 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN691_HUMAN, Q5VV52 (See
protein sequence)Recommended Name: Zinc finger protein 691 Size: 312 amino acids; 35681 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A8MXP6 B4DJR7 O95878 Q9NWE8Alternative splicing: 3 isoforms: Q5VV52-1 Q5VV52-2 Q5VV52-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF691: NX_Q5VV52
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VV52
ZNF691 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001229668.1 NP_056995.1
ENSEMBL proteins: ENSP00000361586 ENSP00000361585 ENSP00000361584 ENSP00000361582 ENSP00000380228 ENSP00000361581 ENSP00000380237 ENSP00000361580 Reactome Protein details: Q5VV52
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF691 for ontologies About GeneDecksing
ZNF691 Antibody Products:
Assay Products for ZNF691: |
Protein
Domains /
Families
for ZNF691 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF691 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5VV52ProtoNet protein and cluster: Q5VV52 UniProtKB/Swiss-Prot: ZN691_HUMAN, Q5VV52Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 7 C2H2-type zinc fingers |
Function
for ZNF691 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN691_HUMAN, Q5VV52Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF691 (NM_015911) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF691 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF691 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF691 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF691 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF691:
|
Pathways & Interactions
for ZNF691 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF691
ZNF691 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF691
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
4 Interacting proteins for ZNF691 (Q5VV522, 3 ENSP000003615844) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ZNF691 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF691
Search CenterWatch for drugs/clinical trials and news about ZNF691 / ZN691
|
Transcripts
for ZNF691 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF691 gene (2 alternative transcripts): NM_001242739.1 NM_015911.3 Unigene Cluster for ZNF691: Zinc finger protein 691 Hs.20879 [show with all ESTs]Unigene Representative Sequence: AK0951848 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372508(uc001cig.3) ENST00000372507(uc001cih.3) ENST00000372506(uc021omh.1 uc009vwm.3)
ENST00000372504 ENST00000397034 ENST00000372503 ENST00000397044 ENST00000372502
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF691 (NM_015911) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF691 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF691 |
Additional cDNA sequence: AF131739.1 AK000938.1 AK095184.1 AK296201.1 BC000157.2 CR457146.1 9 DOTS entries: DT.91922825 DT.91719343 DT.112201 DT.95251889 DT.433194 DT.91719334 DT.100000502 DT.95189569 DT.95376264 24/97 AceView cDNA sequences (see all 97): BC000157 AA581653 CB105122 AA889096 BI763042 BF439326 BQ949046 BM928292 AF131739 AI918174 AI457794 BF948295 BQ052310 NM_015911 BM741761 BM726584 AI565198 AK000938 AA860259 AK095184 AA651685 AA845446 BQ646224 AW206603
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF691 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e |
|---|
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| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF691
|
Expression
for ZNF691 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF691 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF691 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF691
SOURCE GeneReport for Unigene cluster: Hs.20879
SABiosciences Custom PCR Arrays for ZNF691
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF691
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF691 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF691 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF691 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF691 |
Orthologs
for ZNF691 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF691 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for ZNF691 (if available)
TreeFam Gene Tree for ZNF691 (if available) |
Paralogs
for ZNF691 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF691 gene
- ZSCAN22 ZNF4362 ZNF7742 ZNF6292 ZNF5722 ZNF6972 ZNF2052
18/421 SIMAP similar genes for ZNF691 using alignment to 3 protein entries: ZN691_HUMAN (see all proteins)
(see all similar genes):ZNF818P ZNF211 ZFS-5 kr-znf3 ZNF492 ZNF544
DKFZp666C237 ZFP1 ZNF35 ZNF514 ZNF56 ZNF98
ZNF251 ZNF78L1 ZFP2 ZNF500 ZNF551 ZNF569
ZNF691 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF691 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF691 (43312280 - 43318148 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF691: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF691 |
|
Disorders
/ Diseases
for ZNF691 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF691 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF691 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with ZNF691) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (1997)
- A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (1996)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
|
External Searches for ZNF691 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF691 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF691 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF691 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF691 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF691 gene:
Search GeneIP for patents involving ZNF691
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF691 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF691 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF691 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF691 | | | OriGene Protein Over-expression Lysate for ZNF691 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF691 | | OriGene 3'-UTR Clone for ZNF691 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF691 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZNF691 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF691 | | OriGene Custom Protein Services for ZNF691 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF691 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF691 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF691 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF691 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF691 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF691 |
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 | | | ZNF691 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF691 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF691 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF691 |
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