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Aliases for ZNF691 Gene

Aliases for ZNF691 Gene

  • Zinc Finger Protein 691 2 3 5
  • Zfp691 3

External Ids for ZNF691 Gene

Previous GeneCards Identifiers for ZNF691 Gene

  • GC01P042982
  • GC01P043085
  • GC01P043312
  • GC01P041432

Summaries for ZNF691 Gene

GeneCards Summary for ZNF691 Gene

ZNF691 (Zinc Finger Protein 691) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF205.

UniProtKB/Swiss-Prot for ZNF691 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF691 Gene

Genomics for ZNF691 Gene

Regulatory Elements for ZNF691 Gene

Enhancers for ZNF691 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G042923 1.7 Ensembl ENCODE dbSUPER 10.5 +78.2 78180 3.9 CREB3L1 MLX AGO1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 NFYC FOXJ3 SZT2 RNU6-880P ZNF691 ENSG00000228192 FAM183A KDM4A ATP6V1E1P1 ENSG00000284138
GH01G043056 1.7 FANTOM5 Ensembl ENCODE 9.5 +211.7 211708 3.9 HDGF HNRNPUL1 FOXA2 PKNOX1 CREB3L1 ARNT SIN3A YBX1 ZNF766 CBX5 RNU6-880P PPIH LOC105378683 ENSG00000228192 ZNF691 ELOVL1 ENSG00000229431 CFAP57 SLC2A1-AS1 GC01P043056
GH01G042824 1.3 ENCODE dbSUPER 11.1 -21.2 -21230 2.0 HDGF PKNOX1 ATF1 CREB3L1 ARNT SIN3A E2F7 TCF12 ZNF766 ELK1 ENSG00000228192 ZNF691 C1orf50 P3H1 SVBP SZT2
GH01G042823 1.1 ENCODE dbSUPER 11.5 -23.3 -23349 0.2 HDAC1 FEZF1 GATA2 ZSCAN5C CEBPB NR2F2 ZNF592 MAFF PRDM6 SMARCA4 SZT2 ENSG00000228192 ZNF691 PPIH SVBP
GH01G042815 1.1 ENCODE 11.4 -29.5 -29515 2.5 HDGF PKNOX1 FOXA2 MLX SIN3A ARID4B DMAP1 ZNF2 YY1 ZNF143 SVBP PPIH ENSG00000228192 ZNF691 P3H1 SLC2A1-AS1 ERMAP GC01M042733
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF691 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF691 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000005515 27 1601 HDGF PKNOX1 CREB3L1 ARNT MLX ARID4B SIN3A DMAP1 SLC30A9 ZNF766

Genomic Location for ZNF691 Gene

Chromosome:
1
Start:
42,846,573 bp from pter
End:
42,852,477 bp from pter
Size:
5,905 bases
Orientation:
Plus strand

Genomic View for ZNF691 Gene

Genes around ZNF691 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF691 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF691 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF691 Gene

Proteins for ZNF691 Gene

  • Protein details for ZNF691 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VV52-ZN691_HUMAN
    Recommended name:
    Zinc finger protein 691
    Protein Accession:
    Q5VV52
    Secondary Accessions:
    • A8MXP6
    • B4DJR7
    • O95878
    • Q9NWE8

    Protein attributes for ZNF691 Gene

    Size:
    312 amino acids
    Molecular mass:
    35681 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF691 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF691 Gene

Post-translational modifications for ZNF691 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF691 Gene

Domains & Families for ZNF691 Gene

Gene Families for ZNF691 Gene

Protein Domains for ZNF691 Gene

Graphical View of Domain Structure for InterPro Entry

Q5VV52

UniProtKB/Swiss-Prot:

ZN691_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF691: view

Function for ZNF691 Gene

Molecular function for ZNF691 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF691 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF691: view
genes like me logo Genes that share phenotypes with ZNF691: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF691 Gene

Localization for ZNF691 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF691 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF691 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF691 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF691: view

Pathways & Interactions for ZNF691 Gene

SuperPathways for ZNF691 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF691: view

Pathways by source for ZNF691 Gene

2 Reactome pathways for ZNF691 Gene

Interacting Proteins for ZNF691 Gene

Selected Interacting proteins: Q5VV52-ZN691_HUMAN for ZNF691 Gene via IID

Symbol External ID(s) Details
AKT1
HAP1

Gene Ontology (GO) - Biological Process for ZNF691 Gene

None

No data available for SIGNOR curated interactions for ZNF691 Gene

Drugs & Compounds for ZNF691 Gene

No Compound Related Data Available

Transcripts for ZNF691 Gene

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF691 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e
SP1: - -
SP2: - -
SP3: - - - -
SP4: - - - -
SP5: - - - - - -
SP6:

Relevant External Links for ZNF691 Gene

GeneLoc Exon Structure for
ZNF691
ECgene alternative splicing isoforms for
ZNF691

Expression for ZNF691 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF691 Gene

Protein differential expression in normal tissues from HIPED for ZNF691 Gene

This gene is overexpressed in Monocytes (61.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF691 Gene



Protein tissue co-expression partners for ZNF691 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF691 Gene:

ZNF691

SOURCE GeneReport for Unigene cluster for ZNF691 Gene:

Hs.20879

Evidence on tissue expression from TISSUES for ZNF691 Gene

  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with ZNF691: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF691 Gene

Orthologs for ZNF691 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF691 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF691 34 35
  • 99.77 (n)
dog
(Canis familiaris)
Mammalia ZNF691 34 35
  • 90.73 (n)
mouse
(Mus musculus)
Mammalia Zfp691 34 16 35
  • 86.57 (n)
rat
(Rattus norvegicus)
Mammalia Zfp691 34
  • 86.1 (n)
cow
(Bos Taurus)
Mammalia ZNF691 34 35
  • 83.75 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF691 35
  • 43 (a)
OneToOne
Species where no ortholog for ZNF691 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF691 Gene

ENSEMBL:
Gene Tree for ZNF691 (if available)
TreeFam:
Gene Tree for ZNF691 (if available)

Paralogs for ZNF691 Gene

Paralogs for ZNF691 Gene

(424) SIMAP similar genes for ZNF691 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF691: view

Variants for ZNF691 Gene

Sequence variations from dbSNP and Humsavar for ZNF691 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000135457 -- 42,846,974(+) CCGCC(A/G)GCAAT intron-variant, utr-variant-5-prime
rs1000736104 -- 42,848,291(+) ATGGT(A/G)GCGTG intron-variant, utr-variant-5-prime
rs1000892530 -- 42,845,194(+) CAACC(A/G)TATTC downstream-variant-500B, upstream-variant-2KB
rs1000941393 -- 42,845,350(+) ACACA(C/T)GTATA downstream-variant-500B, upstream-variant-2KB
rs1001189350 -- 42,848,024(+) TGAAC(C/T)TAACC intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF691 Gene

Variant ID Type Subtype PubMed ID
esv3577249 CNV gain 25503493

Variation tolerance for ZNF691 Gene

Residual Variation Intolerance Score: 25.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.69; 14.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF691 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF691

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF691 Gene

Disorders for ZNF691 Gene

Relevant External Links for ZNF691

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF691

No disorders were found for ZNF691 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF691 Gene

Publications for ZNF691 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3 64
  5. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3 64

Products for ZNF691 Gene

Sources for ZNF691 Gene

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