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Aliases for ZNF691 Gene

Aliases for ZNF691 Gene

  • Zinc Finger Protein 691 2 3 5
  • Zfp691 3

External Ids for ZNF691 Gene

Previous GeneCards Identifiers for ZNF691 Gene

  • GC01P042982
  • GC01P043085
  • GC01P043312
  • GC01P041432

Summaries for ZNF691 Gene

GeneCards Summary for ZNF691 Gene

ZNF691 (Zinc Finger Protein 691) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF205.

UniProtKB/Swiss-Prot for ZNF691 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF691 Gene

Genomics for ZNF691 Gene

Regulatory Elements for ZNF691 Gene

Enhancers for ZNF691 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F042822 1 Ensembl ENCODE 11.4 -23.6 -23573 1.2 HDAC1 PKNOX1 FEZF1 RARA GATA2 SCRT2 SMARCA5 CEBPB MAFF SMARCA4 CDC20 ZNF691 LOC105378682 SZT2 CFAP57 SVBP
GH01F042819 0.2 Ensembl 11.4 -27.5 -27473 0.2 HDAC1 ATF1 CREM SMARCA5 ZBTB2 USF2 ZEB2 RAD51 SMARCA4 IKZF1 LOC105378682 ZNF691 SZT2 SVBP
GH01F042815 0.7 ENCODE 11.4 -29.5 -29515 2.5 HDGF MLX SIN3A ARID4B DMAP1 ZNF2 YY1 ZNF143 KLF13 SP3 SVBP PPIH LOC105378682 ZNF691 P3H1 SLC2A1-AS1 ERMAP GC01M042733
GH01F042824 0.4 ENCODE 11.1 -21.2 -21230 2.0 HDGF PKNOX1 ATF1 ARNT CREB3L1 SIN3A ELK1 GATA2 ZNF263 JUNB ZNF691 LOC105378682 KDM4A P3H1 C1orf50 SVBP SZT2
GH01F042922 1.1 Ensembl ENCODE 10.5 +78.1 78133 4.0 MLX CREB3L1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 NFYC ZFP41 FOXJ3 SZT2 MKRN8P HNRNPFP1 RNU6-880P LOC105378682 ZNF691 FAM183A KDM4A ATP6V1E1P1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF691 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF691 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000164952 28 2000 HDGF PKNOX1 MLX CREB3L1 ARID4B SIN3A DMAP1 SLC30A9 ZNF143 FOS

Genomic Location for ZNF691 Gene

Chromosome:
1
Start:
42,846,573 bp from pter
End:
42,852,477 bp from pter
Size:
5,905 bases
Orientation:
Plus strand

Genomic View for ZNF691 Gene

Genes around ZNF691 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF691 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF691 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF691 Gene

Proteins for ZNF691 Gene

  • Protein details for ZNF691 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VV52-ZN691_HUMAN
    Recommended name:
    Zinc finger protein 691
    Protein Accession:
    Q5VV52
    Secondary Accessions:
    • A8MXP6
    • B4DJR7
    • O95878
    • Q9NWE8

    Protein attributes for ZNF691 Gene

    Size:
    312 amino acids
    Molecular mass:
    35681 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF691 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF691 Gene

Post-translational modifications for ZNF691 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for ZNF691
  • Santa Cruz Biotechnology (SCBT) Antibodies for ZNF691

No data available for DME Specific Peptides for ZNF691 Gene

Domains & Families for ZNF691 Gene

Gene Families for ZNF691 Gene

Protein Domains for ZNF691 Gene

Graphical View of Domain Structure for InterPro Entry

Q5VV52

UniProtKB/Swiss-Prot:

ZN691_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF691: view

Function for ZNF691 Gene

Molecular function for ZNF691 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF691 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF691: view
genes like me logo Genes that share phenotypes with ZNF691: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF691 Gene

Localization for ZNF691 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF691 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF691 Gene COMPARTMENTS Subcellular localization image for ZNF691 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF691 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF691: view

Pathways & Interactions for ZNF691 Gene

SuperPathways for ZNF691 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF691: view

Pathways by source for ZNF691 Gene

2 Reactome pathways for ZNF691 Gene

Interacting Proteins for ZNF691 Gene

Selected Interacting proteins: Q5VV52-ZN691_HUMAN for ZNF691 Gene via IID

Symbol External ID(s) Details
AKT1
HAP1

Gene Ontology (GO) - Biological Process for ZNF691 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF691: view

No data available for SIGNOR curated interactions for ZNF691 Gene

Transcripts for ZNF691 Gene

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF691 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e
SP1: - -
SP2: - -
SP3: - - - -
SP4: - - - -
SP5: - - - - - -
SP6:

Relevant External Links for ZNF691 Gene

GeneLoc Exon Structure for
ZNF691
ECgene alternative splicing isoforms for
ZNF691

Expression for ZNF691 Gene

mRNA expression in normal human tissues for ZNF691 Gene

Protein differential expression in normal tissues from HIPED for ZNF691 Gene

This gene is overexpressed in Monocytes (61.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF691 Gene



Protein tissue co-expression partners for ZNF691 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF691 Gene:

ZNF691

SOURCE GeneReport for Unigene cluster for ZNF691 Gene:

Hs.20879
genes like me logo Genes that share expression patterns with ZNF691: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF691 Gene

Orthologs for ZNF691 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF691 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF691 34 35
  • 99.77 (n)
dog
(Canis familiaris)
Mammalia ZNF691 34 35
  • 90.73 (n)
mouse
(Mus musculus)
Mammalia Zfp691 34 16 35
  • 86.57 (n)
rat
(Rattus norvegicus)
Mammalia Zfp691 34
  • 86.1 (n)
cow
(Bos Taurus)
Mammalia ZNF691 34 35
  • 83.75 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF691 35
  • 43 (a)
OneToOne
Species where no ortholog for ZNF691 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF691 Gene

ENSEMBL:
Gene Tree for ZNF691 (if available)
TreeFam:
Gene Tree for ZNF691 (if available)

Paralogs for ZNF691 Gene

Paralogs for ZNF691 Gene

(424) SIMAP similar genes for ZNF691 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF691: view

Variants for ZNF691 Gene

Sequence variations from dbSNP and Humsavar for ZNF691 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10890217 -- 42,845,311(+) ACATA(C/T)AATAT downstream-variant-500B, upstream-variant-2KB
rs10890218 -- 42,845,376(+) ACATA(G/T)CTGTA downstream-variant-500B, upstream-variant-2KB
rs111638817 -- 42,852,104(+) ATGCT(C/T)ATGTT utr-variant-3-prime
rs111733502 -- 42,847,162(+) TATCT(A/G)GCTTC intron-variant, utr-variant-5-prime
rs112062939 -- 42,850,888(+) AAAAG(A/G)TTCCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF691 Gene

Variant ID Type Subtype PubMed ID
esv3577249 CNV gain 25503493

Variation tolerance for ZNF691 Gene

Residual Variation Intolerance Score: 25.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.69; 14.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF691 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF691

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF691 Gene

Disorders for ZNF691 Gene

Relevant External Links for ZNF691

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF691

No disorders were found for ZNF691 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF691 Gene

Publications for ZNF691 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3 64
  5. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3 64

Products for ZNF691 Gene

Sources for ZNF691 Gene

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