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Aliases for ZNF687 Gene

Aliases for ZNF687 Gene

  • Zinc Finger Protein 687 2 3
  • KIAA1441 4 6

External Ids for ZNF687 Gene

Previous GeneCards Identifiers for ZNF687 Gene

  • GC01P148069
  • GC01P149520
  • GC01P122632

Summaries for ZNF687 Gene

GeneCards Summary for ZNF687 Gene

ZNF687 (Zinc Finger Protein 687) is a Protein Coding gene. An important paralog of this gene is ZNF592.

UniProtKB/Swiss-Prot for ZNF687 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF687 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF687 Gene

Genomics for ZNF687 Gene

Regulatory Elements for ZNF687 Gene

Genomic Location for ZNF687 Gene

Start:
151,281,618 bp from pter
End:
151,292,180 bp from pter
Size:
10,563 bases
Orientation:
Plus strand

Genomic View for ZNF687 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF687 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF687 Gene

Proteins for ZNF687 Gene

  • Protein details for ZNF687 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N1G0-ZN687_HUMAN
    Recommended name:
    Zinc finger protein 687
    Protein Accession:
    Q8N1G0
    Secondary Accessions:
    • D3DV17
    • Q68DQ8
    • Q9H937
    • Q9P2A7

    Protein attributes for ZNF687 Gene

    Size:
    1237 amino acids
    Molecular mass:
    129529 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA92679.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14406.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAH18162.1; Type=Frameshift; Positions=1062; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF687 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF687 Gene

Proteomics data for ZNF687 Gene at MOPED

Post-translational modifications for ZNF687 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF687 Gene

No data available for DME Specific Peptides for ZNF687 Gene

Domains for ZNF687 Gene

Protein Domains for ZNF687 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF687 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N1G0

UniProtKB/Swiss-Prot:

ZN687_HUMAN :
  • Q8N1G0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF687: view

No data available for Gene Families for ZNF687 Gene

Function for ZNF687 Gene

Molecular function for ZNF687 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF687 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF687: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF687 Gene

Localization for ZNF687 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF687 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF687 Gene COMPARTMENTS Subcellular localization image for ZNF687 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF687 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with ZNF687: view

Pathways for ZNF687 Gene

SuperPathways for ZNF687 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF687 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF687: view

No data available for Pathways by source for ZNF687 Gene

Transcripts for ZNF687 Gene

Unigene Clusters for ZNF687 Gene

Zinc finger protein 687:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF687 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9
SP1: -
SP2:

Relevant External Links for ZNF687 Gene

GeneLoc Exon Structure for
ZNF687
ECgene alternative splicing isoforms for
ZNF687

Expression for ZNF687 Gene

mRNA expression in normal human tissues for ZNF687 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF687 Gene

SOURCE GeneReport for Unigene cluster for ZNF687 Gene Hs.186756

genes like me logo Genes that share expressions with ZNF687: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF687 Gene

Orthologs for ZNF687 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF687 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF687 35
  • 99.65 (n)
  • 99.68 (a)
ZNF687 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF687 35
  • 89.03 (n)
  • 91 (a)
ZNF687 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF687 35
  • 87.75 (n)
  • 89.13 (a)
ZNF687 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp687 35
  • 84.93 (n)
  • 85.88 (a)
Zfp687 16
Zfp687 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF687 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 27 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC100363361 35
  • 83.71 (n)
  • 85.69 (a)
chicken
(Gallus gallus)
Aves ZNF687 35
  • 65.04 (n)
  • 64.75 (a)
ZNF687 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF687 36
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf687 35
  • 65.66 (n)
  • 65.04 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.16948 35
si:dkey-204a24.9 35
  • 55.17 (n)
  • 52.31 (a)
znf687a 36
  • 36 (a)
OneToMany
znf687b 36
  • 34 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
OneToMany
Species with no ortholog for ZNF687:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF687 Gene

ENSEMBL:
Gene Tree for ZNF687 (if available)
TreeFam:
Gene Tree for ZNF687 (if available)

Paralogs for ZNF687 Gene

Paralogs for ZNF687 Gene

Selected SIMAP similar genes for ZNF687 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF687: view

Variants for ZNF687 Gene

Sequence variations from dbSNP and Humsavar for ZNF687 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs2298264 -- 151,286,816(-) AGCGG(A/G)TCTGA synonymous-codon, reference
rs2298265 -- 151,286,567(-) TGCTC(A/G)GGACA reference, synonymous-codon
rs3748545 - 151,287,067(+) TGCTG(A/G)GGTGC missense, reference
rs3748546 -- 151,287,257(+) GCCTC(C/T)AGCTC reference, synonymous-codon
rs3748547 -- 151,290,956(+) ACACC(A/C/G)TTTCA missense, reference

Structural Variations from Database of Genomic Variants (DGV) for ZNF687 Gene

Variant ID Type Subtype PubMed ID
nsv522840 CNV Gain 19592680
dgv2n68 CNV Loss 17160897
esv34461 CNV Gain 17911159

Relevant External Links for ZNF687 Gene

HapMap Linkage Disequilibrium report
ZNF687

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF687 Gene

Disorders for ZNF687 Gene

No disorders were found for ZNF687 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF687 Gene

Publications for ZNF687 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for ZNF687 Gene

Sources for ZNF687 Gene

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