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Aliases for ZNF682 Gene

Aliases for ZNF682 Gene

  • Zinc Finger Protein 682 2 3
  • BC39498_3 3

External Ids for ZNF682 Gene

Previous GeneCards Identifiers for ZNF682 Gene

  • GC19M019978
  • GC19M020115
  • GC19M019677
  • GC19M020696
  • GC19M020952

Summaries for ZNF682 Gene

GeneCards Summary for ZNF682 Gene

ZNF682 (Zinc Finger Protein 682) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF682 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF682 Gene

Genomics for ZNF682 Gene

Regulatory Elements for ZNF682 Gene

Genomic Location for ZNF682 Gene

Start:
19,997,058 bp from pter
End:
20,039,506 bp from pter
Size:
42,449 bases
Orientation:
Minus strand

Genomic View for ZNF682 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF682 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF682 Gene

Proteins for ZNF682 Gene

  • Protein details for ZNF682 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95780-ZN682_HUMAN
    Recommended name:
    Zinc finger protein 682
    Protein Accession:
    O95780
    Secondary Accessions:
    • B3KU64
    • E9PFJ5
    • Q96JV9

    Protein attributes for ZNF682 Gene

    Size:
    498 amino acids
    Molecular mass:
    58361 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB55408.1; Type=Frameshift; Positions=441; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF682 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF682 Gene

Proteomics data for ZNF682 Gene at MOPED

Post-translational modifications for ZNF682 Gene

  • Ubiquitination at Lys97 and Lys432
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF682 Gene

Domains for ZNF682 Gene

Gene Families for ZNF682 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF682 Gene

Suggested Antigen Peptide Sequences for ZNF682 Gene

Graphical View of Domain Structure for InterPro Entry

O95780

UniProtKB/Swiss-Prot:

ZN682_HUMAN :
  • O95780
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF682: view

Function for ZNF682 Gene

Molecular function for ZNF682 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF682 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF682: view

Animal Model Products

CRISPR Products

miRNA for ZNF682 Gene

miRTarBase miRNAs that target ZNF682

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF682 Gene

Localization for ZNF682 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF682 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF682 Gene COMPARTMENTS Subcellular localization image for ZNF682 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF682 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF682: view

Pathways for ZNF682 Gene

SuperPathways for ZNF682 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF682: view

Pathways by source for ZNF682 Gene

2 Reactome pathways for ZNF682 Gene

Interacting Proteins for ZNF682 Gene

Gene Ontology (GO) - Biological Process for ZNF682 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF682: view

Transcripts for ZNF682 Gene

Unigene Clusters for ZNF682 Gene

Zinc finger protein 682:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF682

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF682
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF682 Gene

No ASD Table

Relevant External Links for ZNF682 Gene

GeneLoc Exon Structure for
ZNF682
ECgene alternative splicing isoforms for
ZNF682

Expression for ZNF682 Gene

mRNA expression in normal human tissues for ZNF682 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF682 Gene

SOURCE GeneReport for Unigene cluster for ZNF682 Gene Hs.306298

genes like me logo Genes that share expressions with ZNF682: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF682 Gene

Orthologs for ZNF682 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF682 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF682 35
  • 99.46 (n)
  • 99.4 (a)
ZNF682 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 49 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 35 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp708 36
  • 42 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 36 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 47 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
Species with no ortholog for ZNF682:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF682 Gene

ENSEMBL:
Gene Tree for ZNF682 (if available)
TreeFam:
Gene Tree for ZNF682 (if available)

Paralogs for ZNF682 Gene

Selected SIMAP similar genes for ZNF682 Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF682 Gene

genes like me logo Genes that share paralogs with ZNF682: view

Variants for ZNF682 Gene

Sequence variations from dbSNP and Humsavar for ZNF682 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs963380 -- 20,032,944(+) ggtac(C/T)tgctg intron-variant
rs993044 -- 20,036,276(+) TTCTG(C/T)ATCTG intron-variant
rs1121387 -- 20,039,985(+) GGCGT(C/G)GTAGC upstream-variant-2KB
rs1121388 -- 20,040,010(+) CTAGC(A/T)ACTAG upstream-variant-2KB
rs1319479 -- 20,036,333(+) GTTTT(C/T)TGAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF682 Gene

Variant ID Type Subtype PubMed ID
nsv519535 CNV Gain 19592680
esv2718296 CNV Deletion 23290073
dgv550e201 CNV Deletion 23290073
dgv3792n71 CNV Gain 21882294
esv2718298 CNV Deletion 23290073
nsv458376 CNV Gain 19166990
nsv911319 CNV Gain 21882294
esv2718300 CNV Deletion 23290073
nsv911320 CNV Gain 21882294
dgv630e199 CNV Deletion 23128226
nsv911321 CNV Gain 21882294
nsv911322 CNV Gain 21882294
dgv3793n71 CNV Gain 21882294

Relevant External Links for ZNF682 Gene

HapMap Linkage Disequilibrium report
ZNF682

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF682 Gene

Disorders for ZNF682 Gene

No disorders were found for ZNF682 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF682 Gene

Publications for ZNF682 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF682 Gene

Sources for ZNF682 Gene

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