ZNF679 Gene
protein-coding GIFtS: 43
GCID: GC07P063688
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zinc finger protein 679
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Aliases
for ZNF679 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6791 2 | | MGC424151 | | Hypothetical Protein MGC424152 |
Export aliases for ZNF679 gene to outside databasesPrevious GC identifers: GC07P063134 GC07P063346 GC07P063326 GC07P063490 |
Summaries
for ZNF679 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN679_HUMAN, Q8IYX0Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF679 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079593.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF679
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF679
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF679 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q11.21 Ensembl cytogenetic band: 7q11.21 HGNC cytogenetic band: 7q11.21ZNF679 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P063688: view genomic region
(about GC identifiers)
Start:
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63,688,852 bp from pter |
End:
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63,727,309 bp from pter |
Size:
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38,458 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 63,026,446-63,064,903 |
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Proteins
for ZNF679 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN679_HUMAN, Q8IYX0 (See
protein sequence)Recommended Name: Zinc finger protein 679 Size: 411 amino acids; 47179 Da
Subcellular location: Nucleus (Potential)Explore the universe of human proteins at neXtProt for ZNF679: NX_Q8IYX0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYX0
ZNF679 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_699194.2
ENSEMBL proteins: ENSP00000416809 ENSP00000255746 Reactome Protein details: Q8IYX0
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF679 for ontologies About GeneDecksing
ZNF679 Antibody Products:
Assay Products for ZNF679: |
Protein
Domains /
Families
for ZNF679 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF679 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IYX0ProtoNet protein and cluster: Q8IYX0 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN679_HUMAN, Q8IYX0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 9 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF679 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN679_HUMAN, Q8IYX0Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF679 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF679 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF679 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF679:
|
Pathways & Interactions
for ZNF679 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF679
ZNF679 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF679
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF679 (Q8IYX02, 3 ENSP000002557464) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF679 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF679 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF679
Search CenterWatch for drugs/clinical trials and news about ZNF679 / ZN679
|
Transcripts
for ZNF679 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF679 gene: NM_153363.2 Unigene Cluster for ZNF679: Zinc finger protein 679 Hs.520884 [show with all ESTs]Unigene Representative Sequence: BC0335232 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000421025(uc003tsx.3) ENST00000255746
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF679 (NM_153363) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF679 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF679 |
Additional cDNA sequence: BC033523.1 1 DOTS entry: DT.91653648 3 AceView cDNA sequences: BG717274 BC033523 NM_153363
GeneLoc Exon Structure
|
Expression
for ZNF679 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF679 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF679 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.520884
SABiosciences Custom PCR Arrays for ZNF679
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF679
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF679 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF679 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF679 |
Orthologs
for ZNF679 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF679 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for ZNF679 (if available)
TreeFam Gene Tree for ZNF679 (if available) |
Paralogs
for ZNF679 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF679 gene
- ZNF852 ZNF4932 ZNF4862 ZNF1002 ZNF922 ZNF7322 ZNF1382 ZNF6752
- ZNF5062 ZNF2732 ZNF66P2 ZNF6952 ZNF6262 ZNF6802 ZNF2532 ZNF4792
- ZNF932 ZNF4922 ZNF6822 ZNF6762 ZNF1412 ZNF6812 ZNF2572 ZNF2542
- ZNF7372 ZNF724P2 ZNF982 ZNF849P2 ZNF7162 ZNF7142 ZNF4292 ZNF4302
- ZNF7302 ZNF6782 ZNF1172 ZNF7082 ZNF1072 ZNF4312 ZNF902
18/487 SIMAP similar genes for ZNF679 using alignment to 1 protein entry: ZN679_HUMAN(see all similar genes):ZNF716 ZNF735 MGC12518 ZNF479 ZNF78L1 ZNF273
ZNF718 ZNF66 ZNF738 ZNF506 ZNF300P1 ZNF429
ZNF708 ZFS-1 ZNF232 ZNF430 ZNF431 ZNF492
ZNF679 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF679
PGOHUM00000232989 PGOHUM00000233348
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Genomic Variants
for ZNF679 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF679 (63688852 - 63727309 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF679
1 CNV: 5239 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF679 |
|
Disorders
/ Diseases
for ZNF679 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF679 for disorders About MalaCards
ZNF679 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF679 (1 document)
Export disorders for ZNF679 gene to outside databases
|
Publications
for ZNF679 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF679 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF679) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)1 Barber M.J....Krauss R.M. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
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External Searches for ZNF679 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZNF679 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF679 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF679 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF679 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF679 gene:
Search GeneIP for patents involving ZNF679
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF679 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF679 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF679 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF679 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF679 | | OriGene 3'-UTR Clone for ZNF679 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF679 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | ZNF679 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for ZNF679 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF679 |
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