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Aliases for ZNF679 Gene

Aliases for ZNF679 Gene

  • Zinc Finger Protein 679 2 3
  • Hypothetical Protein MGC42415 2

External Ids for ZNF679 Gene

Previous GeneCards Identifiers for ZNF679 Gene

  • GC07P063134
  • GC07P063346
  • GC07P063326
  • GC07P063688
  • GC07P063490

Summaries for ZNF679 Gene

GeneCards Summary for ZNF679 Gene

ZNF679 (Zinc Finger Protein 679) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF679 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF679 Gene

Genomics for ZNF679 Gene

Genomic Location for ZNF679 Gene

Start:
64,030,542 bp from pter
End:
64,266,931 bp from pter
Size:
236,390 bases
Orientation:
Plus strand

Genomic View for ZNF679 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF679 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF679 Gene

No data available for Regulatory Elements for ZNF679 Gene

Proteins for ZNF679 Gene

  • Protein details for ZNF679 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYX0-ZN679_HUMAN
    Recommended name:
    Zinc finger protein 679
    Protein Accession:
    Q8IYX0
    Secondary Accessions:

    Protein attributes for ZNF679 Gene

    Size:
    411 amino acids
    Molecular mass:
    47179 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF679 Gene

Proteomics data for ZNF679 Gene at MOPED

Post-translational modifications for ZNF679 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF679 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF679 Gene

Domains for ZNF679 Gene

Gene Families for ZNF679 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF679 Gene

Suggested Antigen Peptide Sequences for ZNF679 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IYX0

UniProtKB/Swiss-Prot:

ZN679_HUMAN :
  • Q8IYX0
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF679: view

Function for ZNF679 Gene

Molecular function for ZNF679 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF679 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF679: view

Phenotypes for ZNF679 Gene

GenomeRNAi human phenotypes for ZNF679:
genes like me logo Genes that share phenotypes with ZNF679: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF679

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF679 Gene

Localization for ZNF679 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF679 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF679 Gene COMPARTMENTS Subcellular localization image for ZNF679 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF679 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF679: view

Pathways for ZNF679 Gene

SuperPathways for ZNF679 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF679: view

Pathways by source for ZNF679 Gene

2 Reactome pathways for ZNF679 Gene

Gene Ontology (GO) - Biological Process for ZNF679 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF679: view

Transcripts for ZNF679 Gene

mRNA/cDNA for ZNF679 Gene

(1) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF679 Gene

Zinc finger protein 679:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF679

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF679
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF679 Gene

No ASD Table

Relevant External Links for ZNF679 Gene

GeneLoc Exon Structure for
ZNF679
ECgene alternative splicing isoforms for
ZNF679

Expression for ZNF679 Gene

mRNA expression in normal human tissues for ZNF679 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF679 Gene

This gene is overexpressed in Testis (53.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF679 Gene

SOURCE GeneReport for Unigene cluster for ZNF679 Gene Hs.520884

genes like me logo Genes that share expressions with ZNF679: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF679 Gene

Orthologs for ZNF679 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF679 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF679 35
  • 99.03 (n)
  • 98.05 (a)
ZNF679 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 38 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 29 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp493 36
  • 45 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 27 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 36 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 27 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 22 (a)
ManyToMany
-- 36
  • 20 (a)
ManyToMany
Species with no ortholog for ZNF679:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF679 Gene

ENSEMBL:
Gene Tree for ZNF679 (if available)
TreeFam:
Gene Tree for ZNF679 (if available)

Paralogs for ZNF679 Gene

Selected SIMAP similar genes for ZNF679 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF679 Gene

genes like me logo Genes that share paralogs with ZNF679: view

Variants for ZNF679 Gene

Sequence variations from dbSNP and Humsavar for ZNF679 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs892591 -- 64,232,111(-) cacct(C/G)ccagg intron-variant
rs1005037 -- 64,231,965(-) GAATT(C/G)CATGC intron-variant
rs1404682 -- 64,237,817(+) ataaa(A/C)ctact intron-variant
rs1525168 -- 64,233,851(-) TACAC(A/G)GATTC intron-variant
rs1534102 -- 64,229,750(-) tcata(C/G)ataga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF679 Gene

Variant ID Type Subtype PubMed ID
nsv888255 CNV Loss 21882294
dgv1147e201 CNV Deletion 23290073
nsv888259 CNV Gain 21882294
esv2734573 CNV Deletion 23290073
dgv1212e199 CNV Deletion 23128226
nsv888264 CNV Gain 21882294
nsv522412 CNV Loss 19592680
dgv7306n71 CNV Gain 21882294
esv2422405 CNV Duplication 17116639
nsv888268 CNV Gain 21882294

Relevant External Links for ZNF679 Gene

HapMap Linkage Disequilibrium report
ZNF679

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF679 Gene

Disorders for ZNF679 Gene

Relevant External Links for ZNF679

Genetic Association Database (GAD)
ZNF679
Human Genome Epidemiology (HuGE) Navigator
ZNF679
genes like me logo Genes that share disorders with ZNF679: view

No data available for UniProtKB/Swiss-Prot for ZNF679 Gene

Publications for ZNF679 Gene

  1. Genome-wide association of lipid-lowering response to statins in combined study populations. (PMID: 20339536) Barber M.J. … Krauss R.M. (PLoS ONE 2010) 3 48
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for ZNF679 Gene

Sources for ZNF679 Gene

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