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Aliases for ZNF679 Gene

Aliases for ZNF679 Gene

  • Zinc Finger Protein 679 2 3 5
  • Hypothetical Protein MGC42415 2

External Ids for ZNF679 Gene

Previous GeneCards Identifiers for ZNF679 Gene

  • GC07P063134
  • GC07P063346
  • GC07P063326
  • GC07P063688
  • GC07P063490
  • GC07P064030

Summaries for ZNF679 Gene

GeneCards Summary for ZNF679 Gene

ZNF679 (Zinc Finger Protein 679) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF679 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF679 Gene

Genomics for ZNF679 Gene

Genomic Location for ZNF679 Gene

64,228,474 bp from pter
64,266,931 bp from pter
38,458 bases
Plus strand

Genomic View for ZNF679 Gene

Genes around ZNF679 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF679 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF679 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF679 Gene

No data available for Regulatory Elements for ZNF679 Gene

Proteins for ZNF679 Gene

  • Protein details for ZNF679 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 679
    Protein Accession:

    Protein attributes for ZNF679 Gene

    411 amino acids
    Molecular mass:
    47179 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF679 Gene

Proteomics data for ZNF679 Gene at MOPED

Post-translational modifications for ZNF679 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF679 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF679 Gene

Domains & Families for ZNF679 Gene

Gene Families for ZNF679 Gene

Protein Domains for ZNF679 Gene

Suggested Antigen Peptide Sequences for ZNF679 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF679: view

Function for ZNF679 Gene

Molecular function for ZNF679 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF679 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF679: view

Phenotypes for ZNF679 Gene

genes like me logo Genes that share phenotypes with ZNF679: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF679 Gene

Localization for ZNF679 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF679 Gene

Subcellular locations from

Jensen Localization Image for ZNF679 Gene COMPARTMENTS Subcellular localization image for ZNF679 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF679 Gene

Pathways & Interactions for ZNF679 Gene

SuperPathways for ZNF679 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF679: view

Pathways by source for ZNF679 Gene

2 Reactome pathways for ZNF679 Gene

Gene Ontology (GO) - Biological Process for ZNF679 Gene


No data available for SIGNOR curated interactions for ZNF679 Gene

Drugs & Compounds for ZNF679 Gene

No Compound Related Data Available

Transcripts for ZNF679 Gene

mRNA/cDNA for ZNF679 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF679 Gene

Zinc finger protein 679:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF679 Gene

No ASD Table

Relevant External Links for ZNF679 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF679 Gene

mRNA expression in normal human tissues for ZNF679 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF679 Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for ZNF679 Gene

This gene is overexpressed in Rectum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF679 Gene

SOURCE GeneReport for Unigene cluster for ZNF679 Gene Hs.520884

genes like me logo Genes that share expression patterns with ZNF679: view

Protein tissue co-expression partners for ZNF679 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF679 Gene

Orthologs for ZNF679 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF679 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF679 35
  • 99.03 (n)
  • 98.05 (a)
ZNF679 36
  • 98 (a)
(Bos Taurus)
Mammalia -- 36
  • 38 (a)
(Canis familiaris)
Mammalia -- 36
  • 29 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 27 (a)
-- 36
  • 38 (a)
(Mus musculus)
Mammalia Zfp493 36
  • 45 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 36 (a)
-- 36
  • 24 (a)
-- 36
  • 30 (a)
-- 36
  • 27 (a)
-- 36
  • 23 (a)
-- 36
  • 22 (a)
-- 36
  • 22 (a)
-- 36
  • 20 (a)
Species with no ortholog for ZNF679:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF679 Gene

Gene Tree for ZNF679 (if available)
Gene Tree for ZNF679 (if available)

Paralogs for ZNF679 Gene

(488) SIMAP similar genes for ZNF679 Gene using alignment to 1 proteins: Pseudogenes for ZNF679 Gene

genes like me logo Genes that share paralogs with ZNF679: view

Variants for ZNF679 Gene

Sequence variations from dbSNP and Humsavar for ZNF679 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs12154540 - 64,260,873(+) TCTGG(A/G)GCAAA reference, missense
rs17139320 - 64,265,992(+) TGGAC(A/G)TGACA reference, missense
rs1830035 - 64,266,267(+) ATTCC(C/T)ACCAA reference, missense
rs1830036 - 64,266,300(+) TCAAC(A/T)GCTCT reference, missense
rs892591 -- 64,232,111(-) cacct(C/G)ccagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF679 Gene

Variant ID Type Subtype PubMed ID
nsv888255 CNV Loss 21882294
dgv1147e201 CNV Deletion 23290073
nsv888259 CNV Gain 21882294
esv2734573 CNV Deletion 23290073
dgv1212e199 CNV Deletion 23128226
nsv888264 CNV Gain 21882294
nsv522412 CNV Loss 19592680
dgv7306n71 CNV Gain 21882294
esv2422405 CNV Duplication 17116639
nsv888268 CNV Gain 21882294

Variation tolerance for ZNF679 Gene

Residual Variation Intolerance Score: 89% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.62; 89.07% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF679 Gene

Disorders for ZNF679 Gene

Relevant External Links for ZNF679

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF679 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF679 Gene

Publications for ZNF679 Gene

  1. Genome-wide association of lipid-lowering response to statins in combined study populations. (PMID: 20339536) Barber M.J. … Krauss R.M. (PLoS ONE 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for ZNF679 Gene

Sources for ZNF679 Gene