Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZNF678 Gene

protein-coding GIFtS: 47
GCID: GC01P227751

zinc finger protein 678

Explore 2 diseases affiliated with
ZNF678 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger Protein 678¹ ²
MGC42493¹
Hypothetical Protein MGC42493²

External Ids:	HGNC: 28652¹	Entrez Gene: 339500²	Ensembl: ENSG00000181450⁷	UniProtKB: Q5SXM1³

ORGUL members:
	NONCODE:n409083

Export aliases for ZNF678 gene to outside databases

Previous GC identifers: GC01P224141 GC01P225817 GC01P198267

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN678_HUMAN, Q5SXM1

Function: May be involved in transcriptional regulation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZNF678 gene promoter:
RORalpha1 AP-2rep ZIC2/Zic2 LCR-F1 En-1 RORalpha2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF678 promoter sequence

Search SABiosciences Chromatin IP Primers for ZNF678

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF678

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.13 Ensembl cytogenetic band: 1q42.13 HGNC cytogenetic band: 1q42.13

ZNF678 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF678 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P227751: view genomic region (about GC identifiers)

Start:	227,751,220 bp from pter	End:	227,850,164 bp from pter
Size:	98,945 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN678_HUMAN, Q5SXM1 (See protein sequence)

Recommended Name: Zinc finger protein 678

Size: 525 amino acids; 61411 Da

Subcellular location: Nucleus (Probable)

Secondary accessions: Q8IVQ9

Explore the universe of human proteins at neXtProt for ZNF678: NX_Q5SXM1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5SXM1

ZNF678 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_848644.2

ENSEMBL proteins:

ENSP00000344828 ENSP00000394651 ENSP00000440403

Reactome Protein details: Q5SXM1
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for ZNF678
	GenScript Custom Purified and Recombinant Proteins Services for ZNF678
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ZNF678

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	IEA	--

ZNF678 for ontologies About GeneDecksing

ZNF678 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for ZNF678
	GenScript Custom Superior Antibodies Services for ZNF678
	Novus Biologicals ZNF678 Antibody
	Search for Antibodies for ZNF678 at Abcam
	Uscn Antibodies for ZNF678
	ThermoFisher Antibodies for ZNF678

Assay Products for ZNF678:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZNF678
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ZNF678

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF678 for domains About GeneDecksing

3 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q5SXM1

ProtoNet protein and cluster: Q5SXM1

UniProtKB/Swiss-Prot: ZN678_HUMAN, Q5SXM1

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 15 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ZN678_HUMAN, Q5SXM1

Function: May be involved in transcriptional regulation

miRNA Products:		OriGene 3'-UTR Clone: ZNF678 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF678
		1 QIAGEN miScript miRNA Assays for microRNA that regulate ZNF678:
		hsa-miR-1208
		SwitchGear 3'UTR luciferase reporter plasmid: ZNF678 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF678 OriGene shRNA RFP: ZNF678 OriGene siRNA: ZNF678
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF678

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ZNF678

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ZNF678 (NM_178549)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF678
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF678

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ZNF678
		Search LifeMap BioReagents cell lines for ZNF678

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF678

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	--	--
GO:0003677	DNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--

ZNF678 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for ZNF678:

Decreased BPV1 E2 protein expr

Increased HPV18 LCR reporter a

Synthetic lethal with c-Myc af

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Generic Transcription Pathway

Generic Transcription Pathway

1.00

Gene Expression

0.46

Pathway sources
See GeneCards unified pathways
Show all pathways

2 Reactome Pathways for ZNF678

	Generic Transcription Pathway
	Gene Expression

ZNF678 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZNF678

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

ZNF678 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF678
Search CenterWatch for drugs/clinical trials and news about ZNF678 / ZN678

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZNF678 gene (2 alternative transcripts):

NM_032755.1 NM_178549.3

Unigene Cluster for ZNF678:

Zinc finger protein 678

Hs.30323 [show with all ESTs]

Unigene Representative Sequence: NR_033184

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000498759(uc021pjy.1 uc001hqw.2) ENST00000343776(uc009xet.2)

ENST00000465266 ENST00000440339 ENST00000497098 ENST00000397097(uc009xeu.2)

miRNA Products:		OriGene 3'-UTR Clone: ZNF678 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF678
		1 QIAGEN miScript miRNA Assays for microRNA that regulate ZNF678:
		hsa-miR-1208
		SwitchGear 3'UTR luciferase reporter plasmid: ZNF678 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF678 OriGene shRNA RFP: ZNF678 OriGene siRNA: ZNF678
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF678

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ZNF678 (NM_178549)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF678
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF678

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF678 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat ZNF678
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF678
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF678

Additional cDNA sequence:

AB074269.1 AK026475.1 AK307248.1 AK311313.1 BC007286.1 BC042500.1 NR_033184.1

9 DOTS entries:

DT.111483 DT.91962700 DT.91989596 DT.100710757 DT.434181 DT.121447820 DT.97786909 DT.95252917

DT.91917593

24/33 AceView cDNA sequences (see all 33):

BM474693 AA234071 AA004774 BF701740 BG723184 AK026475 BI253975 AW341269

AU253723 AI638115 AV698906 BC042500 AA194947 AA677900 NM_178549 AA047700

AA004701 CD655825 BF197308 BG255294 AA704749 CF146171 AA489196 BX473670

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF678 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTTGGCCC

About this image
See ZNF678 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF678

SOURCE GeneReport for Unigene cluster: Hs.30323

SABiosciences Custom PCR Arrays for ZNF678

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF678 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat ZNF678
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF678
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF678

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF678

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZNF678 gene from 1/4 species (see all 4) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	-- -- (see all 7)	--	48(a) 45(a) (see all 7)	many ↔ many many ↔ many (see all 7)	GL343330.1(1093706-1292239) AAWZ02037240(11818-13836)

ENSEMBL Gene Tree for ZNF678 (if available)
TreeFam Gene Tree for ZNF678 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZNF678 gene

ZNF85² ZNF493² ZNF486² ZNF100² ZNF92² ZNF732² ZNF138² ZNF675²

ZNF506² ZNF273² ZNF66P² ZNF695² ZNF626² ZNF680² ZNF253² ZNF479²

ZNF93² ZNF492² ZNF682² ZNF676² ZNF141² ZNF681² ZNF679² ZNF257²

ZNF254² ZNF737² ZNF724P² ZNF98² ZNF849P² ZNF716² ZNF714² ZNF429²

ZNF430² ZNF730² ZNF117² ZNF708² ZNF107² ZNF431² ZNF90²

18/539 SIMAP similar genes for ZNF678 using alignment to 3 protein entries: ZN678_HUMAN (see all proteins) (see all similar genes):

kr-znf3 ZNF345 ZFS-1 ZNF78L1 ZNF826P DKFZp686B16128

HZF30 smap-7 ZFS-6 DKFZp686H10254 ZNF818P ZNF808

DKFZp434G1930 DKFZp686M04222 HZF41 HZF36 ZNF626 ZNF660

ZNF678 for paralogs About GeneDecksing

4 Pseudogenes.org Pseudogenes for ZNF678
PGOHUM00000239011 PGOHUM00000250743 PGOHUM00000260244 PGOHUM00000233788

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11801101^1,2	C,F,H,	--	227749228(+)	`GGGAGG/AGCCGG`	2	--	us2k¹ tfbs³		2		NA WA	124
rs4653513^1,2	C,H,	--	227749339(+)	`CGCTGC/GCACTG`	2	--	us2k¹		11		NA WA CSA	257
rs182917377^1,2		--	227749377(+)	`GGAAGA/CGGGCC`	2	--	us2k¹		0	--	--	--	--
rs147285953^1,2		--	227749577(+)	`CGGTGC/TCACAG`	2	--	us2k¹		0	--	--	--	--
rs12745552^1,2	C,F,H,	--	227749587(+)	`GCTCTC/GGCTAG`	2	--	us2k¹		21		NS EA NA	2518
rs148440977^1,2		--	227749758(+)	`TGTTCA/TGGCCC`	2	--	us2k¹		0	--	--	--	--
rs141676577^1,2		--	227749765(+)	`GCCCAA/GCCCAA`	2	--	us2k¹		0	--	--	--	--
rs12033610^1,2	C,F,A,H,	--	227749852(+)	`TGGCTC/GTGTAA`	2	--	us2k¹ tfbs³		21		EA NA NS WA	2554
rs150517630^1,2		--	227749887(+)	`TCCCCC/TTCCAC`	2	--	us2k¹		0	--	--	--	--
rs139515308^1,2	C,	--	227749914(+)	`AGCCT-/TCTC TCTCT`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZNF678 (227751220 - 227850164 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF678: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF678

DNA2.0 Custom Variant and Variant Library Synthesis for ZNF678

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNF678 for disorders About GeneDecksing

2 diseases for ZNF678: About MalaCards

pediatric crohns disease crohn's disease

Human Genome Epidemiology (HuGE) Navigator: ZNF678 (3 documents)

Export disorders for ZNF678 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZNF678 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF678)

Utopia: connect your pdf to the dynamic
world of online information

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)¹ Zhao J....Grant S.F. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. (PubMed id 20846217)¹ Lee J.J....Hirschhorn J. (2010)
Genome-wide association analysis identifies 20 loci that influence adult height. (PubMed id 18391952)¹ Weedon M.N....Frayling T.M. (2008)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 339500	HGNC: 28652	AceView: MGC42493	Ensembl:ENSG00000181450	euGenes: HUgn339500
ECgene: ZNF678	H-InvDB: ZNF678

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZNF678	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZNF678 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ZNF678 gene:
Search GeneIP for patents involving ZNF678

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for ZNF678
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF678		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF678
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for ZNF678		OriGene 3'-UTR Clone for ZNF678
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF678
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for ZNF678		OriGene Custom Protein Services for ZNF678
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF678
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF678
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF678
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF678
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF678
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF678

	GenScript Custom Purified and Recombinant Proteins Services for ZNF678		GenScript cDNA clones with any tag delivered in your preferred vector for ZNF678
	GenScript Custom Assay Services for ZNF678		GenScript Custom Superior Antibodies Services for ZNF678
	GenScript Custom overexpressing Cell Line Services for ZNF678		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in ZNF678 promoter
	Search Chromatin IP Primers for ZNF678
	RT² qPCR Primer Assay in human, mouse / rat ZNF678
	Search GNC Networks for ZNF678
	SABiosciences Custom PCR Arrays for ZNF678

Search Tocris compounds for ZNF678

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	ZNF678 antibodies

	Search for Antibodies for ZNF678 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for ZNF678
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

ZNF678 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for ZNF678

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF678

	SwitchGear 3'UTR luciferase reporter plasmids for ZNF678
	SwitchGear Promoter luciferase reporter plasmids for ZNF678

ThermoFisher Antibodies for ZNF678

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF678

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZNF678 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

ZNF678 Gene

zinc finger protein 678

Aliases
for ZNF678 gene

Summaries
for ZNF678 gene

Genomic Views
for ZNF678 gene

Proteins
for ZNF678 gene

Protein Domains /
Families
for ZNF678 gene

Function
for ZNF678 gene

Pathways & Interactions
for ZNF678 gene

Drugs & Compounds
for ZNF678 gene

Transcripts
for ZNF678 gene

Expression
for ZNF678 gene

Orthologs
for ZNF678 gene

Paralogs
for ZNF678 gene

Genomic Variants
for ZNF678 gene

Disorders / Diseases
for ZNF678 gene

Publications
for ZNF678 gene

External Searches for ZNF678 gene

Genome Databases showing ZNF678 gene

Other Databases showing ZNF678 gene

Specialized Databases showing ZNF678 gene

Intellectual Property
for ZNF678 gene

Products
for ZNF678 gene

View Random Gene

Advanced Search

Export list of displayed genes

ZNF678 Gene

zinc finger protein 678

Aliasesfor ZNF678 gene

Summariesfor ZNF678 gene

Genomic Viewsfor ZNF678 gene

Proteinsfor ZNF678 gene

Protein Domains /Familiesfor ZNF678 gene

Functionfor ZNF678 gene

Pathways & Interactionsfor ZNF678 gene

Drugs & Compoundsfor ZNF678 gene

Transcriptsfor ZNF678 gene

Expression for ZNF678 gene

Orthologsfor ZNF678 gene

Paralogsfor ZNF678 gene

Genomic Variantsfor ZNF678 gene

Disorders / Diseasesfor ZNF678 gene

Publicationsfor ZNF678 gene

External Searches for ZNF678 gene

Genome Databases showing ZNF678 gene

Other Databases showing ZNF678 gene

Specialized Databases showing ZNF678 gene

Intellectual Propertyfor ZNF678 gene

Productsfor ZNF678 gene

View Random Gene

Aliases
for ZNF678 gene

Summaries
for ZNF678 gene

Genomic Views
for ZNF678 gene

Proteins
for ZNF678 gene

Protein Domains /
Families
for ZNF678 gene

Function
for ZNF678 gene

Pathways & Interactions
for ZNF678 gene

Drugs & Compounds
for ZNF678 gene

Transcripts
for ZNF678 gene

Expression
for ZNF678 gene

Orthologs
for ZNF678 gene

Paralogs
for ZNF678 gene

Genomic Variants
for ZNF678 gene

Disorders / Diseases
for ZNF678 gene

Publications
for ZNF678 gene

Intellectual Property
for ZNF678 gene

Products
for ZNF678 gene