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Aliases for ZNF677 Gene

Aliases for ZNF677 Gene

  • Zinc Finger Protein 677 2 3
  • Hypothetical Protein MGC48625 2

External Ids for ZNF677 Gene

Summaries for ZNF677 Gene

GeneCards Summary for ZNF677 Gene

ZNF677 (Zinc Finger Protein 677) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF677 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF677 Gene

Genomics for ZNF677 Gene

Genomic Location for ZNF677 Gene

Start:
53,235,381 bp from pter
End:
53,254,966 bp from pter
Size:
19,586 bases
Orientation:
Minus strand

Genomic View for ZNF677 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF677 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF677 Gene

Regulatory Elements for ZNF677 Gene

Transcription factor binding sites by QIAGEN in the ZNF677 gene promoter:

Proteins for ZNF677 Gene

  • Protein details for ZNF677 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XU0-ZN677_HUMAN
    Recommended name:
    Zinc finger protein 677
    Protein Accession:
    Q86XU0
    Secondary Accessions:

    Protein attributes for ZNF677 Gene

    Size:
    584 amino acids
    Molecular mass:
    67996 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF677 Gene

Proteomics data for ZNF677 Gene at MOPED

Post-translational modifications for ZNF677 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF677 Gene

No data available for DME Specific Peptides for ZNF677 Gene

Domains for ZNF677 Gene

Gene Families for ZNF677 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF677 Gene

UniProtKB/Swiss-Prot:

ZN677_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q86XU0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q86XU0
Similarity:
  • Contains 10 C2H2-type zinc fingers.:
    • Q86XU0
genes like me logo Genes that share domains with ZNF677: view

Function for ZNF677 Gene

Molecular function for ZNF677 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF677: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF677 Gene

Localization for ZNF677 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF677 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF677 Gene COMPARTMENTS Subcellular localization image for ZNF677 gene
Compartment Confidence
nucleus 4
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZNF677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF677: view

Pathways for ZNF677 Gene

SuperPathways for ZNF677 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF677: view

Pathways by source for ZNF677 Gene

2 Reactome pathways for ZNF677 Gene

Interacting Proteins for ZNF677 Gene

Gene Ontology (GO) - Biological Process for ZNF677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF677: view

Transcripts for ZNF677 Gene

Unigene Clusters for ZNF677 Gene

Zinc finger protein 677:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF677 Gene

No ASD Table

Relevant External Links for ZNF677 Gene

GeneLoc Exon Structure for
ZNF677
ECgene alternative splicing isoforms for
ZNF677

Expression for ZNF677 Gene

mRNA expression in normal human tissues for ZNF677 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF677 Gene

This gene is overexpressed in Testis (5.0).

SOURCE GeneReport for Unigene cluster for ZNF677 Gene Hs.20506

genes like me logo Genes that share expressions with ZNF677: view

Orthologs for ZNF677 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF677 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF677 36
  • 98.97 (n)
  • 98.97 (a)
ZNF677 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF677 36
  • 74.81 (n)
  • 59.83 (a)
ZNF677 37
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF677 37
  • 62 (a)
OneToOne
Species with no ortholog for ZNF677:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF677 Gene

ENSEMBL:
Gene Tree for ZNF677 (if available)
TreeFam:
Gene Tree for ZNF677 (if available)

Paralogs for ZNF677 Gene

Selected SIMAP similar genes for ZNF677 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF677 Gene

genes like me logo Genes that share paralogs with ZNF677: view

Variants for ZNF677 Gene

Sequence variations from dbSNP and Humsavar for ZNF677 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1129002 -- 53,238,900(-) CTTCA(A/T)ATATG intron-variant
rs1139315 -- 53,238,382(-) GTAAA(A/C)AATTA reference, missense
rs1469440 -- 53,256,268(-) GTTAC(A/G)AAAAC upstream-variant-2KB
rs1966573 -- 53,256,018(-) ACTTC(A/G)TGAGG upstream-variant-2KB
rs2865240 -- 53,249,766(+) TATTT(A/T)ATAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF677 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV Deletion 23290073
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073

Relevant External Links for ZNF677 Gene

HapMap Linkage Disequilibrium report
ZNF677

Disorders for ZNF677 Gene

No disorders were found for ZNF677 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF677 Gene

Publications for ZNF677 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers. (PMID: 25504438) Heller G. … ZAPchbauer-MA1ller S. (Oncotarget 2015) 2 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3

Products for ZNF677 Gene

  • antibodies-online peptides for ZNF677
  • antibodies-online antibodies for ZNF677
  • antibodies-online kits for ZNF677

Sources for ZNF677 Gene

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