Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZNF674 Gene

protein-coding   GIFtS: 42
GCID: GC0XM046358

Zinc Finger Protein 674


(Previous symbol: MRX92)
  See ZNF674-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Zinc Finger Protein 6741 2
MRX921 2
ZNF673B2
Zinc Finger Family Member 6742

External Ids:    HGNC: 176251   Entrez Gene: 6413392   Ensembl: ENSG000002511927   OMIM: 3005735   UniProtKB: Q2M3X93   
ORGUL members:         

Export aliases for ZNF674 gene to outside databases

Previous GC identifers: GC00U921661 GC0XM046243 GC0XM044070


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ZNF674 Gene:
This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11
Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription
factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental
retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. (provided
by RefSeq, Jun 2010)

GeneCards Summary for ZNF674 Gene:
ZNF674 (zinc finger protein 674) is a protein-coding gene. Diseases associated with ZNF674 include xp11.3 deletion syndrome, and znf674-related x-linked mental retardation. An important paralog of this gene is ZNF175.

UniProtKB/Swiss-Prot: ZN674_HUMAN, Q2M3X9
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_079573.5  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF674 gene promoter:
         RFX1   Tal-1   ARP-1   ZID   Tal-1beta   ITF-2   E47   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZNF674

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF674


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.3   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.3

ZNF674 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF674 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM046358:  view genomic region     (about GC identifiers)

Start:
46,357,160 bp from pter      End:
46,404,892 bp from pter
Size:
47,733 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZN674_HUMAN, Q2M3X9 (See protein sequence)
Recommended Name: Zinc finger protein 674  
Size: 581 amino acids; 67199 Da
Developmental stage: Expressed in fetal brain
Caution: Although ZNF674 has been reported to be involved in X-linked mental retardation (PubMed:16385466), its
pathological role is questionable (PubMed:23871722)
Secondary accessions: B4DHE2 E9PHQ4
Alternative splicing: 2 isoforms:  Q2M3X9-1   Q2M3X9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF674: NX_Q2M3X9

Explore proteomics data for ZNF674 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF674 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001034980.1  NP_001139763.1  NP_001177346.1  

    ENSEMBL proteins: 
     ENSP00000429148   ENSP00000428248   ENSP00000429646  

    ZNF674 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZNF674
    GenScript Custom Purified and Recombinant Proteins Services for ZNF674
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF674

     
    Search eBioscience for Proteins for ZNF674 

    ZNF674 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF674
    Novus Biologicals ZNF674 Antibodies
    Abcam antibodies for ZNF674
    Cloud-Clone Corp. Antibodies for ZNF674
    Search ThermoFisher Antibodies for ZNF674
    LSBio Antibodies in human, mouse, rat for ZNF674

    ZNF674 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZNF674
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF674
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZNF674
    Cloud-Clone Corp. CLIAs for ZNF674
    Search eBioscience for ELISAs for ZNF674 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q2M3X9

    ProtoNet protein and cluster: Q2M3X9

    1 Blocks protein domain: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: ZN674_HUMAN, Q2M3X9
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 11 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF674           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN674_HUMAN, Q2M3X9
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF674           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF674
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZNF674

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF674
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF674

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ZNF674 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate ZNF674:
    hsa-miR-513c hsa-miR-3647-3p hsa-miR-1912 hsa-miR-1297 hsa-miR-188-3p hsa-miR-26a hsa-miR-514b-5p hsa-miR-26b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF674
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF674

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF674

    Clone
    Products:
         
    OriGene clones in human, mouse for ZNF674 (see all 11)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ZNF674 (NM_001039891)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF674
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF674

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF674
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF674 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF674


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZN674_HUMAN, Q2M3X9: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF674           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF674
    Interactions:

        Search GeneGlobe Interaction Network for ZNF674

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with ZNF674           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF674 (ZN674)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZNF674 gene (3 alternative transcripts): 
    NM_001039891.2  NM_001146291.1  NM_001190417.1  

    Unigene Cluster for ZNF674:

    Zinc finger protein 674
    Hs.636105  [show with all ESTs]
    Unigene Representative Sequence: NM_001039891
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000523374(uc011mlg.2 uc022bvl.1 uc004dgr.3) ENST00000414387
    ENST00000518795 ENST00000521626 ENST00000522017(uc010nhm.2) ENST00000518708
    ENST00000453909
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZNF674 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate ZNF674:
    hsa-miR-513c hsa-miR-3647-3p hsa-miR-1912 hsa-miR-1297 hsa-miR-188-3p hsa-miR-26a hsa-miR-514b-5p hsa-miR-26b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF674
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF674
    Clone
    Products:
         
    OriGene clones in human, mouse for ZNF674 (see all 11)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ZNF674 (NM_001039891)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF674
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF674
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF674
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF674
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF674
      QuantiFast Probe-based Assays in human, mouse, rat ZNF674

    Additional mRNA sequence: 

    AK130892.1 AK295054.1 AK308986.1 AY971607.1 BX648127.1 

    6 DOTS entries:

    DT.97789458  DT.91752331  DT.40211055  DT.92420903  DT.408353  DT.99933524 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZNF674 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAACAAAAAG
    ZNF674 Expression
    About this image

    ZNF674 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF674 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.636105

    UniProtKB/Swiss-Prot: ZN674_HUMAN, Q2M3X9
    Tissue specificity: Expressed in testis

        Custom PCR Arrays for ZNF674
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF674
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF674
    QuantiTect SYBR Green Assays in human, mouse, rat ZNF674
    QuantiFast Probe-based Assays in human, mouse, rat ZNF674
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF674

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of mammals.

    Orthologs for ZNF674 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia LOC4918501 zinc finger protein 674-like 86.32(n)
    80(a)
      491850  XM_005641292.1  XP_005641349.1 


    ENSEMBL Gene Tree for ZNF674 (if available)
    TreeFam Gene Tree for ZNF674 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZNF674 gene
    ZNF1752  ZNF4872  ZNF5102  ZIM32  ZNF6142  ZNF1572  ZNF262  ZNF6132  
    ZNF812  ZNF6492  ENSG000002673602  ZNF7822  ZNF7932  ZNF252  ZNF5682  ENSG000002365752  
    ENSG000002296312  ZNF5672  ZNF1822  ZNF37A2  ZNF2482  ZNF3002  ZNF3822  RBAK-RBAKDN2  
    Selected SIMAP similar genes for ZNF674 using alignment to 2 protein entries:     ZN674_HUMAN (see all proteins) (see all similar genes):
    KRBOX4    FIK    ZNF78L1    DKFZp666C237    ZFS-4    ZNF702P
    ZNF93    ZNF675    ZNF81    ZFP41    ZNF232    ZNF32
    ZSCAN30    ZNF415    ZFP90    ZNF350    ZKSCAN5    ZNF621

    Find genes that share paralogs with ZNF674           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ZNF674
    PGOHUM00000241535


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZNF674 (see all 681)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1998154411,2
    --46275486(+) CCAAG-/TCCCTG 3 -- ds50010--------
    rs1858017761,2
    --46275530(+) CTGTAC/TTAATC 3 -- ds50010--------
    rs1382781061,2
    --46275829(+) GTATAC/TATATG 3 -- ds50010--------
    rs1496028361,2
    C--46275905(+) TGGATA/GGGAAA 3 -- ds50010--------
    rs59528931,2
    C,F,A,H--46275930(+) CGTAAT/GATACA 3 -- ds500120Minor allele frequency- G:0.24NS EA NA 2081
    rs1902149401,2
    --46275944(+) TAAACA/GATATA 3 -- ut310--------
    rs1379188751,2
    C--46276075(+) CACTAC/TACAGA 3 -- ut310--------
    rs2020995771,2
    --46276124(+) ACACA-/CTCACCT 3 -- ut310--------
    rs1825145631,2
    --46276183(+) ACTTAC/TATGTG 3 -- ut310--------
    rs1423806801,2
    C--46276328(+) TACCAC/TGAACA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF674 (46357160 - 46404892 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZNF674: --
    Human Gene Mutation Database (HGMD): ZNF674
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ZNF674
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF674

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 300573    OMIM disorders: --

    3 diseases for ZNF674:    
    About MalaCards
    xp11.3 deletion syndrome    znf674-related x-linked mental retardation    mental retardation, x-linked 17/31, microduplication

    1 disease from the University of Copenhagen DISEASES database for ZNF674:
    Fundus dystrophy

    Find genes that share disorders with ZNF674           About GenesLikeMe


    Export disorders for ZNF674 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZNF674 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF674)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ZNF674: a new Kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation. (PubMed id 16385466)1, 2, 3 Lugtenberg D.... van Bokhoven H. (Am. J. Hum. Genet. 2006)
    2. XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing. (PubMed id 23871722)2 Piton A....Mandel J.L. (Am. J. Hum. Genet. 2013)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Intellectual disability associated with retinal dystrophy in the Xp11.3 deletion syndrome: ZNF674 on trial. Guilty or innocent? (PubMed id 22126752)1 Delphin N....Rozet J.M. (Eur. J. Hum. Genet. 2012)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (Science 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 641339 HGNC: 17625 Ensembl:ENSG00000251192 euGenes: HUgn641339 ECgene: ZNF674
    H-InvDB: ZNF674

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZNF674 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZNF674 gene:
    Search GeneIP for patents involving ZNF674

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZNF674  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZNF674  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZNF674   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF674   OriGene Custom Protein Services for ZNF674  

     
     
     Block miRNA regulation of human, mouse, rat ZNF674 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZNF674
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF674 Predesigned siRNA for gene silencing in human, mouse, rat ZNF674
     QuantiFast Probe-based Assays in human, mouse, rat ZNF674 QuantiTect SYBR Green Assays in human, mouse, rat ZNF674
     Custom PCR Arrays for ZNF674 Search Chromatin IP Primers for ZNF674
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF674  Search GeneGlobe Interaction Network for ZNF674
     Regulatory tfbs in ZNF674 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZNF674 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF674
     GenScript Custom Assay Services for ZNF674 GenScript Custom overexpressing Cell Line Services for ZNF674
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZNF674 (ZN674)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZNF674 antibodies
     Antibodies for ZNF674
     See all of Abcam's Antibodies, Kits and Proteins for ZNF674
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZNF674
     Antibodies for ZNF674
     ELISAs for ZNF674
     CLIAs for ZNF674



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF674
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF674
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ZNF674
     Browse SwitchGear Promoter luciferase reporter plasmids for ZNF674
     Search ThermoFisher Antibodies for ZNF674
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF674
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF674
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZNF674
     LSBio Antibodies in human, mouse, rat for ZNF674
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZNF674
      Search eBioscience for proteins for ZNF674
      Search eBioscience for elisas for ZNF674
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF674 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4