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Aliases for ZNF672 Gene

Aliases for ZNF672 Gene

  • Zinc Finger Protein 672 2 3 5
  • Hypothetical Protein FLJ22301 2

External Ids for ZNF672 Gene

Previous GeneCards Identifiers for ZNF672 Gene

  • GC01P245343
  • GC01P247099
  • GC01P249132
  • GC01P219373

Summaries for ZNF672 Gene

GeneCards Summary for ZNF672 Gene

ZNF672 (Zinc Finger Protein 672) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF672 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF672 Gene

Genomics for ZNF672 Gene

Regulatory Elements for ZNF672 Gene

Promoters for ZNF672 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF672 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF672 Gene

Chromosome:
1
Start:
248,838,178 bp from pter
End:
248,849,517 bp from pter
Size:
11,340 bases
Orientation:
Plus strand

Genomic View for ZNF672 Gene

Genes around ZNF672 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF672 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF672 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF672 Gene

Proteins for ZNF672 Gene

  • Protein details for ZNF672 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q499Z4-ZN672_HUMAN
    Recommended name:
    Zinc finger protein 672
    Protein Accession:
    Q499Z4
    Secondary Accessions:
    • Q96H65
    • Q96IM3
    • Q9H6G5

    Protein attributes for ZNF672 Gene

    Size:
    452 amino acids
    Molecular mass:
    50224 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF672 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF672 Gene

Proteomics data for ZNF672 Gene at MOPED

Post-translational modifications for ZNF672 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF672 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF672 Gene

Domains & Families for ZNF672 Gene

Gene Families for ZNF672 Gene

Protein Domains for ZNF672 Gene

Suggested Antigen Peptide Sequences for ZNF672 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q499Z4

UniProtKB/Swiss-Prot:

ZN672_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF672: view

Function for ZNF672 Gene

Molecular function for ZNF672 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF672: view

Animal Model Products

CRISPR Products

miRNA for ZNF672 Gene

miRTarBase miRNAs that target ZNF672

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF672 Gene

Localization for ZNF672 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF672 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF672 Gene COMPARTMENTS Subcellular localization image for ZNF672 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF672 Gene

Pathways & Interactions for ZNF672 Gene

SuperPathways for ZNF672 Gene

No Data Available

Interacting Proteins for ZNF672 Gene

Gene Ontology (GO) - Biological Process for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF672: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF672 Gene

Drugs & Compounds for ZNF672 Gene

No Compound Related Data Available

Transcripts for ZNF672 Gene

Unigene Clusters for ZNF672 Gene

Zinc finger protein 672:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF672 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - -
SP6: - - - - - -
SP7: - - - -
SP8: -

Relevant External Links for ZNF672 Gene

GeneLoc Exon Structure for
ZNF672
ECgene alternative splicing isoforms for
ZNF672

Expression for ZNF672 Gene

mRNA expression in normal human tissues for ZNF672 Gene

Protein differential expression in normal tissues from HIPED for ZNF672 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (66.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF672 Gene



SOURCE GeneReport for Unigene cluster for ZNF672 Gene Hs.521151

genes like me logo Genes that share expression patterns with ZNF672: view

Protein tissue co-expression partners for ZNF672 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF672 Gene

Orthologs for ZNF672 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF672 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF672 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF672 36
  • 80 (a)
OneToOne
ZNF672 35
  • 80.93 (n)
  • 82.26 (a)
dog
(Canis familiaris)
Mammalia ZNF672 35
  • 79.57 (n)
  • 78.08 (a)
ZNF672 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp672 16
Zfp672 36
  • 75 (a)
OneToOne
Zfp672 35
  • 75.09 (n)
  • 77.61 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF672 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp672 35
  • 74.35 (n)
  • 77.83 (a)
Species with no ortholog for ZNF672:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF672 Gene

ENSEMBL:
Gene Tree for ZNF672 (if available)
TreeFam:
Gene Tree for ZNF672 (if available)

Paralogs for ZNF672 Gene

(484) SIMAP similar genes for ZNF672 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF672: view

No data available for Paralogs for ZNF672 Gene

Variants for ZNF672 Gene

Sequence variations from dbSNP and Humsavar for ZNF672 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs13985 -- 248,848,186(-) GTGTG(A/G)ATGCG reference, synonymous-codon
rs6663379 -- 248,843,027(+) CCAGG(G/T)CTGTC intron-variant
rs11205420 -- 248,836,403(+) TTCCA(C/T)AAACA upstream-variant-2KB
rs11205424 -- 248,840,257(+) ggcta(A/C)ttttt intron-variant
rs11205427 -- 248,841,833(+) gaatc(G/T)cttga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF672 Gene

Variant ID Type Subtype PubMed ID
esv2750832 CNV Gain 17911159
esv2750835 CNV Gain 17911159
nsv5398 CNV Insertion 18451855

Variation tolerance for ZNF672 Gene

Gene Damage Index Score: 0.73; 15.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF672 Gene

HapMap Linkage Disequilibrium report
ZNF672

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF672 Gene

Disorders for ZNF672 Gene

Relevant External Links for ZNF672

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF672

No disorders were found for ZNF672 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF672 Gene

Publications for ZNF672 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF672 Gene

Sources for ZNF672 Gene

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