ZNF672 Gene
protein-coding GIFtS: 43
GCID: GC01P249132
|
|
zinc finger protein 672
| |
Aliases
for ZNF672 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6721 2 | | FLJ223011 |
Export aliases for ZNF672 gene to outside databasesPrevious GC identifers: GC01P245343 GC01P247099 GC01P219373 |
Summaries
for ZNF672 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN672_HUMAN, Q499Z4Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF672 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032968.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF672 gene promoter:
HEN1 Sox5 AML1a deltaCREB STAT3 Olf-1 C/EBPalpha RSRFC4 Evi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF672
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF672 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q44 Ensembl cytogenetic band: 1q44 HGNC cytogenetic band: 1q44ZNF672 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P249132: view genomic region
(about GC identifiers)
Start:
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249,132,409 bp from pter |
End:
|
249,143,716 bp from pter |
Size:
|
11,308 bases |
Orientation:
|
plus strand |
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Proteins
for ZNF672 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN672_HUMAN, Q499Z4 (See
protein sequence)Recommended Name: Zinc finger protein 672 Size: 452 amino acids; 50224 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q96H65 Q96IM3 Q9H6G5Alternative splicing: 2 isoforms: Q499Z4-1 Q499Z4-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF672: NX_Q499Z4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q499Z4
ZNF672 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079112.1
ENSEMBL proteins: ENSP00000421915 ENSP00000422534 ENSP00000427021 ENSP00000426199
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF672 for ontologies About GeneDecksing
ZNF672 Antibody Products:
Assay Products for ZNF672: |
Protein
Domains /
Families
for ZNF672 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF672 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q499Z4ProtoNet protein and cluster: Q499Z4 UniProtKB/Swiss-Prot: ZN672_HUMAN, Q499Z4Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 14 C2H2-type zinc fingers |
Function
for ZNF672 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN672_HUMAN, Q499Z4Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF672 (NM_024836) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF672 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF672 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF672 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF672 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF672 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF672
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF672 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF672 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF672
Search CenterWatch for drugs/clinical trials and news about ZNF672 / ZN672
|
Transcripts
for ZNF672 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF672 gene: NM_024836.1 Unigene Cluster for ZNF672: Zinc finger protein 672 Hs.521151 [show with all ESTs]Unigene Representative Sequence: BC0351407 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000510904 ENST00000306562(uc001iex.3) ENST00000505503 ENST00000428515
ENST00000502697 ENST00000515369 ENST00000423362
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF672 (NM_024836) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF672 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF672 |
Additional cDNA sequence: AK025954.1 AK027476.1 AK027679.1 AK298016.1 BC007385.2 BC008872.1 BC029310.1 BC035140.1 BC050348.1 BC068506.1 19 DOTS entries: DT.100760993 DT.448777 DT.101979769 DT.100814734 DT.100814730 DT.121352101 DT.100814733 DT.121352065 DT.70104370 DT.121352141 DT.92441029 DT.97792462 DT.121351972 DT.121352018 DT.121352156 DT.121352170 DT.86998566 DT.121351959 DT.99983397 24/288 AceView cDNA sequences (see all 288): BM126938 AA912334 AI039895 BQ575562 BX418393 BC029310 BM924505 AW024219 BM547482 AI375714 AI566547 AW188003 BI523738 AK025954 AA344361 AI671463 AI554036 AI217783 BU729232 BX420430 BG385925 AI393172 AW087312 CA426615
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF672 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF672
|
Expression
for ZNF672 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF672 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTAGTGAAA
About this image
See ZNF672 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF672
SOURCE GeneReport for Unigene cluster: Hs.521151
SABiosciences Custom PCR Arrays for ZNF672
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF672
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF672 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF672 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF672 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF672 |
Orthologs
for ZNF672 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF672 gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for ZNF672 (if available)
TreeFam Gene Tree for ZNF672 (if available) |
Paralogs
for ZNF672 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF672 gene
- ZNF5762
18/481 SIMAP similar genes for ZNF672 using alignment to 3 protein entries: ZN672_HUMAN (see all proteins)
(see all similar genes):ZNF696 DKFZp666C237 ZSCAN29 ZKSCAN1 ZNF ZNF554
ZNF850 ZNF324 ZNF391 ZNF500 ZNF514 ZNF679
ZNF78L1 ZNF891 ZNF84 ZNF434 ZNF589 ZSCAN32
ZNF672 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF672 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF672 (249132409 - 249143716 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF672
2 CNVs: 8355 8354 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF672 |
|
Disorders
/ Diseases
for ZNF672 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF672 for disorders About GeneDecksing
1  disease for ZNF672: About MalaCardsmicrocephaly
Export disorders for ZNF672 gene to outside databases
|
Publications
for ZNF672 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF672 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF672) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF672 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF672 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF672 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF672 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF672 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF672 gene:
Search GeneIP for patents involving ZNF672
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF672 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF672 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF672 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF672 | | | OriGene Protein Over-expression Lysate for ZNF672 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF672 | | OriGene 3'-UTR Clone for ZNF672 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF672 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF672 | | OriGene Custom Protein Services for ZNF672 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF672 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF672 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF672 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF672 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF672 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF672 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF672 |
| |  |  |  |  | | | | |
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 |
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 | | | ZNF672 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF672 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF672 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF672 |
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