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Aliases for ZNF672 Gene

Aliases for ZNF672 Gene

  • Zinc Finger Protein 672 2 3 5
  • Hypothetical Protein FLJ22301 2

External Ids for ZNF672 Gene

Previous GeneCards Identifiers for ZNF672 Gene

  • GC01P245343
  • GC01P247099
  • GC01P249132
  • GC01P219373

Summaries for ZNF672 Gene

GeneCards Summary for ZNF672 Gene

ZNF672 (Zinc Finger Protein 672) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF672 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF672 Gene

Genomics for ZNF672 Gene

Regulatory Elements for ZNF672 Gene

Enhancers for ZNF672 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G248924 1.2 Ensembl ENCODE 11.5 +87.8 87768 2.5 HDGF PKNOX1 ATF1 ARNT RAD21 RFX5 TCF12 ZNF143 IKZF2 CREM ZNF672 ENSG00000227237 ZNF692 PGBD2 SH3BP5L PIR45582 PIR40629 GC01P248921
GH01G248816 0.8 Ensembl ENCODE 11.9 -21.2 -21178 1.2 CEBPB MAX MYC SPI1 ZNF672 ZNF692 ENSG00000227237 PGBD2 SH3BP5L MIR3124 GC01P248810
GH01G248886 0.8 Ensembl dbSUPER 11.6 +48.5 48523 0.2 NFIC PBX2 IKZF1 ZNF592 RNU6-1205P ZNF672 ZNF692 ENSG00000227237 SH3BP5L PIR34959 TRE-CTC2-1
GH01G248883 0.4 dbSUPER 11.6 +45.4 45415 0.1 IRF1 RNU6-1205P ZNF672 ZNF692 ENSG00000227237 SH3BP5L PIR34959 TRE-CTC2-1
GH01G248862 1.8 FANTOM5 Ensembl ENCODE dbSUPER 1.6 +25.1 25123 1.4 ATF1 AGO1 ARID4B SIN3A DMAP1 ZNF48 YY1 GLIS2 ZNF143 SP5 SH3BP5L ZNF692 OR14I1 ZNF672 PGBD2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF672 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF672 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000023267 422 1601 HDGF PKNOX1 CREB3L1 AGO1 WRNIP1 ARID4B SIN3A YY1 SLC30A9 ZNF207

Genomic Location for ZNF672 Gene

Chromosome:
1
Start:
248,838,178 bp from pter
End:
248,849,517 bp from pter
Size:
11,340 bases
Orientation:
Plus strand

Genomic View for ZNF672 Gene

Genes around ZNF672 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF672 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF672 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF672 Gene

Proteins for ZNF672 Gene

  • Protein details for ZNF672 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q499Z4-ZN672_HUMAN
    Recommended name:
    Zinc finger protein 672
    Protein Accession:
    Q499Z4
    Secondary Accessions:
    • Q96H65
    • Q96IM3
    • Q9H6G5

    Protein attributes for ZNF672 Gene

    Size:
    452 amino acids
    Molecular mass:
    50224 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF672 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF672 Gene

Post-translational modifications for ZNF672 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF672 Gene

No data available for DME Specific Peptides for ZNF672 Gene

Domains & Families for ZNF672 Gene

Gene Families for ZNF672 Gene

Protein Domains for ZNF672 Gene

Suggested Antigen Peptide Sequences for ZNF672 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q499Z4

UniProtKB/Swiss-Prot:

ZN672_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF672: view

Function for ZNF672 Gene

Molecular function for ZNF672 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF672: view
genes like me logo Genes that share phenotypes with ZNF672: view

Animal Model Products

CRISPR Products

miRNA for ZNF672 Gene

miRTarBase miRNAs that target ZNF672

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF672 Gene

Localization for ZNF672 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF672 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF672 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF672: view

Pathways & Interactions for ZNF672 Gene

SuperPathways for ZNF672 Gene

No Data Available

Interacting Proteins for ZNF672 Gene

Gene Ontology (GO) - Biological Process for ZNF672 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF672: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF672 Gene

Drugs & Compounds for ZNF672 Gene

No Compound Related Data Available

Transcripts for ZNF672 Gene

Unigene Clusters for ZNF672 Gene

Zinc finger protein 672:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF672 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
SP1: - - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - -
SP6: - - - - - -
SP7: - - - -
SP8: -

Relevant External Links for ZNF672 Gene

GeneLoc Exon Structure for
ZNF672
ECgene alternative splicing isoforms for
ZNF672

Expression for ZNF672 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF672 Gene

Protein differential expression in normal tissues from HIPED for ZNF672 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (66.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF672 Gene



Protein tissue co-expression partners for ZNF672 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF672 Gene:

ZNF672

SOURCE GeneReport for Unigene cluster for ZNF672 Gene:

Hs.521151

Evidence on tissue expression from TISSUES for ZNF672 Gene

  • Nervous system(4.8)
genes like me logo Genes that share expression patterns with ZNF672: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF672 Gene

Orthologs for ZNF672 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF672 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF672 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF672 34 35
  • 80.93 (n)
dog
(Canis familiaris)
Mammalia ZNF672 34 35
  • 79.57 (n)
mouse
(Mus musculus)
Mammalia Zfp672 34 16 35
  • 75.09 (n)
rat
(Rattus norvegicus)
Mammalia Zfp672 34
  • 74.35 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF672 35
  • 64 (a)
OneToOne
Species where no ortholog for ZNF672 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF672 Gene

ENSEMBL:
Gene Tree for ZNF672 (if available)
TreeFam:
Gene Tree for ZNF672 (if available)

Paralogs for ZNF672 Gene

(484) SIMAP similar genes for ZNF672 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF672: view

No data available for Paralogs for ZNF672 Gene

Variants for ZNF672 Gene

Sequence variations from dbSNP and Humsavar for ZNF672 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000038682 -- 248,841,069(+) GGATA(C/T)GATGA intron-variant
rs1000358394 -- 248,849,310(+) CAGAA(C/T)CATGT utr-variant-3-prime
rs1000967767 -- 248,844,109(+) TTTTC(A/G)ATTAT intron-variant
rs1001336152 -- 248,840,981(+) TAGTA(C/T)TTGTA intron-variant
rs1001429295 -- 248,841,762(+) GCTAA(A/G)AATAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF672 Gene

Variant ID Type Subtype PubMed ID
dgv631n100 CNV gain 25217958
dgv644n100 CNV gain 25217958
esv2750832 CNV gain 17911159
esv2750835 CNV gain 17911159
esv3589576 CNV gain 21293372
esv3589577 CNV gain 21293372
nsv5398 CNV insertion 18451855
nsv549745 CNV loss 21841781
nsv999043 CNV gain 25217958

Variation tolerance for ZNF672 Gene

Gene Damage Index Score: 0.73; 15.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF672 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF672

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF672 Gene

Disorders for ZNF672 Gene

Relevant External Links for ZNF672

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF672

No disorders were found for ZNF672 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF672 Gene

Publications for ZNF672 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64

Products for ZNF672 Gene

Sources for ZNF672 Gene

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