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Aliases for ZNF670 Gene

Aliases for ZNF670 Gene

  • Zinc Finger Protein 670 2 3 5

External Ids for ZNF670 Gene

Previous GeneCards Identifiers for ZNF670 Gene

  • GC01M243527
  • GC01M245266
  • GC01M247200
  • GC01M217593
  • GC01M247111
  • GC01M247114

Summaries for ZNF670 Gene

GeneCards Summary for ZNF670 Gene

ZNF670 (Zinc Finger Protein 670) is a Protein Coding gene. Diseases associated with ZNF670 include Vitreous Disease. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF669.

UniProtKB/Swiss-Prot for ZNF670 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF670 Gene

Genomics for ZNF670 Gene

Regulatory Elements for ZNF670 Gene

Enhancers for ZNF670 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF670 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF670 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF670 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF670 Gene

Chromosome:
1
Start:
247,034,638 bp from pter
End:
247,078,813 bp from pter
Size:
44,176 bases
Orientation:
Minus strand

Genomic View for ZNF670 Gene

Genes around ZNF670 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF670 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF670 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF670 Gene

Proteins for ZNF670 Gene

  • Protein details for ZNF670 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BS34-ZN670_HUMAN
    Recommended name:
    Zinc finger protein 670
    Protein Accession:
    Q9BS34

    Protein attributes for ZNF670 Gene

    Size:
    389 amino acids
    Molecular mass:
    44603 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF670 Gene

Post-translational modifications for ZNF670 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF670 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF670 Gene

Domains & Families for ZNF670 Gene

Gene Families for ZNF670 Gene

Protein Domains for ZNF670 Gene

Suggested Antigen Peptide Sequences for ZNF670 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BS34

UniProtKB/Swiss-Prot:

ZN670_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF670: view

Function for ZNF670 Gene

Molecular function for ZNF670 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 23455924
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF670: view
genes like me logo Genes that share phenotypes with ZNF670: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF670 Gene

Localization for ZNF670 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF670 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF670 Gene COMPARTMENTS Subcellular localization image for ZNF670 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2

Gene Ontology (GO) - Cellular Components for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF670: view

Pathways & Interactions for ZNF670 Gene

SuperPathways for ZNF670 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF670: view

Pathways by source for ZNF670 Gene

2 Reactome pathways for ZNF670 Gene

Gene Ontology (GO) - Biological Process for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF670: view

No data available for SIGNOR curated interactions for ZNF670 Gene

Drugs & Compounds for ZNF670 Gene

No Compound Related Data Available

Transcripts for ZNF670 Gene

mRNA/cDNA for ZNF670 Gene

Unigene Clusters for ZNF670 Gene

Zinc finger protein 670:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF670 Gene

No ASD Table

Relevant External Links for ZNF670 Gene

GeneLoc Exon Structure for
ZNF670
ECgene alternative splicing isoforms for
ZNF670

Expression for ZNF670 Gene

mRNA expression in normal human tissues for ZNF670 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF670 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF670 Gene:

ZNF670

SOURCE GeneReport for Unigene cluster for ZNF670 Gene:

Hs.732305
genes like me logo Genes that share expression patterns with ZNF670: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF670 Gene

Orthologs for ZNF670 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF670 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF670 34
  • 99.83 (n)
  • 99.49 (a)
Species where no ortholog for ZNF670 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF670 Gene

ENSEMBL:
Gene Tree for ZNF670 (if available)
TreeFam:
Gene Tree for ZNF670 (if available)

Paralogs for ZNF670 Gene

(503) SIMAP similar genes for ZNF670 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF670: view

Variants for ZNF670 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF670 Gene

Variant ID Type Subtype PubMed ID
esv2672680 CNV deletion 23128226
esv29446 CNV loss 19812545
esv33129 CNV gain+loss 17666407
esv3589499 CNV loss 21293372
esv3589503 CNV loss 21293372
esv3589504 CNV loss 21293372
esv3589505 CNV loss 21293372
nsv1014012 CNV loss 25217958
nsv549546 CNV loss 21841781
nsv549547 CNV loss 21841781
nsv999879 CNV gain 25217958

Variation tolerance for ZNF670 Gene

Residual Variation Intolerance Score: 26.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.78; 16.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF670 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF670

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZNF670 Gene

Disorders for ZNF670 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF670 Gene - From: DISEASES

Disorder Aliases PubMed IDs
vitreous disease
  • disorder of vitreous body
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZNF670

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF670
genes like me logo Genes that share disorders with ZNF670: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF670 Gene

Publications for ZNF670 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65
  2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3 4 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65

Products for ZNF670 Gene

Sources for ZNF670 Gene

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