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Aliases for ZNF670 Gene

Aliases for ZNF670 Gene

  • Zinc Finger Protein 670 2 3

External Ids for ZNF670 Gene

Previous GeneCards Identifiers for ZNF670 Gene

  • GC01M243527
  • GC01M245266
  • GC01M247200
  • GC01M217593
  • GC01M247111
  • GC01M247114

Summaries for ZNF670 Gene

GeneCards Summary for ZNF670 Gene

ZNF670 (Zinc Finger Protein 670) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF670 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF670 Gene

Genomics for ZNF670 Gene

Regulatory Elements for ZNF670 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF670 Gene

Chromosome:
1
Start:
247,034,638 bp from pter
End:
247,078,813 bp from pter
Size:
44,176 bases
Orientation:
Minus strand

Genomic View for ZNF670 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF670 Gene

Proteins for ZNF670 Gene

  • Protein details for ZNF670 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BS34-ZN670_HUMAN
    Recommended name:
    Zinc finger protein 670
    Protein Accession:
    Q9BS34

    Protein attributes for ZNF670 Gene

    Size:
    389 amino acids
    Molecular mass:
    44603 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF670 Gene

Proteomics data for ZNF670 Gene at MOPED

Post-translational modifications for ZNF670 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF670 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF670 Gene

Domains & Families for ZNF670 Gene

Gene Families for ZNF670 Gene

Protein Domains for ZNF670 Gene

Suggested Antigen Peptide Sequences for ZNF670 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BS34

UniProtKB/Swiss-Prot:

ZN670_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF670: view

Function for ZNF670 Gene

Molecular function for ZNF670 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 23455924
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF670: view

Phenotypes for ZNF670 Gene

genes like me logo Genes that share phenotypes with ZNF670: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF670

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF670 Gene

Localization for ZNF670 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF670 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF670 Gene COMPARTMENTS Subcellular localization image for ZNF670 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 2

Gene Ontology (GO) - Cellular Components for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF670: view

Pathways & Interactions for ZNF670 Gene

SuperPathways for ZNF670 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF670: view

Pathways by source for ZNF670 Gene

2 Reactome pathways for ZNF670 Gene

Gene Ontology (GO) - Biological Process for ZNF670 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF670: view

No data available for SIGNOR curated interactions for ZNF670 Gene

Drugs & Compounds for ZNF670 Gene

No Compound Related Data Available

Transcripts for ZNF670 Gene

mRNA/cDNA for ZNF670 Gene

Unigene Clusters for ZNF670 Gene

Zinc finger protein 670:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF670

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF670 Gene

No ASD Table

Relevant External Links for ZNF670 Gene

GeneLoc Exon Structure for
ZNF670
ECgene alternative splicing isoforms for
ZNF670

Expression for ZNF670 Gene

mRNA expression in normal human tissues for ZNF670 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF670 Gene



SOURCE GeneReport for Unigene cluster for ZNF670 Gene Hs.732305

genes like me logo Genes that share expression patterns with ZNF670: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF670 Gene

Orthologs for ZNF670 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF670 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF670 35
  • 99.83 (n)
  • 99.49 (a)
Species with no ortholog for ZNF670:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF670 Gene

ENSEMBL:
Gene Tree for ZNF670 (if available)
TreeFam:
Gene Tree for ZNF670 (if available)

Paralogs for ZNF670 Gene

(503) SIMAP similar genes for ZNF670 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF670: view

No data available for Paralogs for ZNF670 Gene

Variants for ZNF670 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF670 Gene

Variant ID Type Subtype PubMed ID
nsv873424 CNV Gain 21882294
esv33129 CNV Gain+Loss 17666407
nsv873427 CNV Loss 21882294
nsv873428 CNV Loss 21882294
dgv562n71 CNV Loss 21882294
esv2672680 CNV Deletion 23128226
esv29446 CNV Loss 19812545

Variation tolerance for ZNF670 Gene

Residual Variation Intolerance Score: 26.27% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.78; 16.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF670 Gene

HapMap Linkage Disequilibrium report
ZNF670

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZNF670 Gene

Disorders for ZNF670 Gene

Relevant External Links for ZNF670

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF670
genes like me logo Genes that share disorders with ZNF670: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF670 Gene

Publications for ZNF670 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 67
  4. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. (PMID: 23006423) Niu N. … Wang L. (BMC Cancer 2012) 67
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67

Products for ZNF670 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF670
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF670
    • Block miRNA regulation of ZNF670 using miScript Target Protectors

    Sources for ZNF670 Gene

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