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Aliases for ZNF667 Gene

Aliases for ZNF667 Gene

  • Zinc Finger Protein 667 2 3
  • MIPU1 3 6
  • Myocardial Ischemic Preconditioning Upregulated 1 Ortholog 3

External Ids for ZNF667 Gene

Previous GeneCards Identifiers for ZNF667 Gene

  • GC19M061644
  • GC19M056951
  • GC19M053259

Summaries for ZNF667 Gene

GeneCards Summary for ZNF667 Gene

ZNF667 (Zinc Finger Protein 667) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF667 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF667 Gene

Genomics for ZNF667 Gene

Regulatory Elements for ZNF667 Gene

Genomic Location for ZNF667 Gene

Start:
56,439,324 bp from pter
End:
56,478,065 bp from pter
Size:
38,742 bases
Orientation:
Minus strand

Genomic View for ZNF667 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF667 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF667 Gene

Proteins for ZNF667 Gene

  • Protein details for ZNF667 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5HYK9-ZN667_HUMAN
    Recommended name:
    Zinc finger protein 667
    Protein Accession:
    Q5HYK9
    Secondary Accessions:
    • B2RMS6
    • B9EK36
    • Q6B093
    • Q9H807

    Protein attributes for ZNF667 Gene

    Size:
    610 amino acids
    Molecular mass:
    70161 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH74898.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH74899.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF667 Gene

Proteomics data for ZNF667 Gene at MOPED

Post-translational modifications for ZNF667 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF667 Gene

No data available for DME Specific Peptides for ZNF667 Gene

Domains for ZNF667 Gene

Gene Families for ZNF667 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF667 Gene

Suggested Antigen Peptide Sequences for ZNF667 Gene

Graphical View of Domain Structure for InterPro Entry

Q5HYK9

UniProtKB/Swiss-Prot:

ZN667_HUMAN :
  • Q5HYK9
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF667: view

Function for ZNF667 Gene

Molecular function for ZNF667 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF667 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003712 transcription cofactor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF667: view

Animal Model Products

CRISPR Products

miRNA for ZNF667 Gene

miRTarBase miRNAs that target ZNF667

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF667 Gene

Localization for ZNF667 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF667 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF667 Gene COMPARTMENTS Subcellular localization image for ZNF667 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF667 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF667: view

Pathways for ZNF667 Gene

SuperPathways for ZNF667 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF667: view

Pathways by source for ZNF667 Gene

2 Reactome pathways for ZNF667 Gene

Gene Ontology (GO) - Biological Process for ZNF667 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF667: view

Transcripts for ZNF667 Gene

Unigene Clusters for ZNF667 Gene

Zinc finger protein 667:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF667

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF667

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF667 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d
SP1: - - - - -
SP2: - - - - - - - - - - -
SP3: - - - - - - - -
SP4: -
SP5: - - - - - - - - - -
SP6: - - - - - -
SP7: - - -
SP8: -
SP9: - - - -

Relevant External Links for ZNF667 Gene

GeneLoc Exon Structure for
ZNF667
ECgene alternative splicing isoforms for
ZNF667

Expression for ZNF667 Gene

mRNA expression in normal human tissues for ZNF667 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF667 Gene

This gene is overexpressed in Pituitary (5.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF667 Gene

SOURCE GeneReport for Unigene cluster for ZNF667 Gene Hs.676605

genes like me logo Genes that share expressions with ZNF667: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZNF667 Gene

Orthologs for ZNF667 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF667 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF667 35
  • 99.67 (n)
  • 99.67 (a)
ZNF667 36
  • 82 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF667 35
  • 88.42 (n)
  • 86.56 (a)
ZNF667 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF667 35
  • 88.42 (n)
  • 83.77 (a)
ZNF667 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp667 35
  • 80.01 (n)
  • 74.79 (a)
Zfp667 16
Zfp667 36
  • 75 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp667 35
  • 80.8 (n)
  • 76.24 (a)
Species with no ortholog for ZNF667:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF667 Gene

ENSEMBL:
Gene Tree for ZNF667 (if available)
TreeFam:
Gene Tree for ZNF667 (if available)

Paralogs for ZNF667 Gene

Selected SIMAP similar genes for ZNF667 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF667: view

No data available for Paralogs for ZNF667 Gene

Variants for ZNF667 Gene

Sequence variations from dbSNP and Humsavar for ZNF667 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1542038 -- 56,472,909(+) ACCAA(C/T)GAAGA intron-variant
rs1542039 -- 56,473,006(+) GGCAA(C/T)GTCTT intron-variant
rs1988918 -- 56,453,172(+) aatca(G/T)gaaga intron-variant
rs2165048 -- 56,440,740(+) CAAGC(A/G)ATTCT utr-variant-3-prime, nc-transcript-variant
rs2165049 -- 56,456,312(+) gattc(A/T)aagca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF667 Gene

Variant ID Type Subtype PubMed ID
nsv912516 CNV Gain 21882294
esv1044797 CNV Insertion 17803354
esv2719037 CNV Deletion 23290073
esv2719038 CNV Deletion 23290073
esv268963 CNV Insertion 20981092
esv273931 CNV Insertion 20981092

Relevant External Links for ZNF667 Gene

HapMap Linkage Disequilibrium report
ZNF667

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF667 Gene

Disorders for ZNF667 Gene

Relevant External Links for ZNF667

Genetic Association Database (GAD)
ZNF667
Human Genome Epidemiology (HuGE) Navigator
ZNF667
genes like me logo Genes that share disorders with ZNF667: view

No data available for UniProtKB/Swiss-Prot for ZNF667 Gene

Publications for ZNF667 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3

Products for ZNF667 Gene

  • antibodies-online peptides for ZNF667
  • antibodies-online antibodies for ZNF667
  • antibodies-online kits for ZNF667

Sources for ZNF667 Gene

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