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Aliases for ZNF664-FAM101A Gene

Aliases for ZNF664-FAM101A Gene

  • Filamin-Interacting Protein FAM101A 3
  • Regulator Of Filamin Protein A 3 4
  • RefilinA 3 4
  • ZNF664-FAM101A Readthrough 3
  • Protein FAM101A 3
  • FAM101A 4

External Ids for ZNF664-FAM101A Gene

Previous GeneCards Identifiers for ZNF664-FAM101A Gene

  • GC12U901544
  • GC12P124459

Summaries for ZNF664-FAM101A Gene

Entrez Gene Summary for ZNF664-FAM101A Gene

  • This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 664 (GeneID 144348) and hypothetical protein LOC144347 (GeneID 144347) genes on chromosome 12. The read-through transcript produces a protein that shares sequence identity with the downstream hypothetical protein LOC144347 locus. [provided by RefSeq, Feb 2011]

GeneCards Summary for ZNF664-FAM101A Gene

ZNF664-FAM101A (Filamin-Interacting Protein FAM101A) is a Protein Coding gene. An important paralog of this gene is FAM101B.

UniProtKB/Swiss-Prot for ZNF664-FAM101A Gene

  • Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF664-FAM101A Gene

Genomics for ZNF664-FAM101A Gene

Genomic Location for ZNF664-FAM101A Gene

123,973,215 bp from pter
124,316,024 bp from pter
342,810 bases
Plus strand

Genomic View for ZNF664-FAM101A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF664-FAM101A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF664-FAM101A Gene

No data available for Regulatory Elements for ZNF664-FAM101A Gene

Proteins for ZNF664-FAM101A Gene

  • Protein details for ZNF664-FAM101A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Filamin-interacting protein FAM101A
    Protein Accession:
    Secondary Accessions:
    • A5D8T5

    Protein attributes for ZNF664-FAM101A Gene

    216 amino acids
    Molecular mass:
    23610 Da
    Quaternary structure:
    • Interacts with FLNA and FLNB.

    Alternative splice isoforms for ZNF664-FAM101A Gene


neXtProt entry for ZNF664-FAM101A Gene

Proteomics data for ZNF664-FAM101A Gene at MOPED

Protein Expression for ZNF664-FAM101A Gene

Post-translational modifications for ZNF664-FAM101A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF664-FAM101A Gene

No data available for DME Specific Peptides for ZNF664-FAM101A Gene

Domains for ZNF664-FAM101A Gene

Protein Domains for ZNF664-FAM101A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM101 family.
  • Belongs to the FAM101 family.
genes like me logo Genes that share domains with ZNF664-FAM101A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for ZNF664-FAM101A Gene

Function for ZNF664-FAM101A Gene

Molecular function for ZNF664-FAM101A Gene

UniProtKB/Swiss-Prot Function:
Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells.

Gene Ontology (GO) - Molecular Function for ZNF664-FAM101A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF664-FAM101A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF664-FAM101A Gene

Localization for ZNF664-FAM101A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF664-FAM101A Gene

Cytoplasm, cytoskeleton. Note=Colocalizes with FLNA along actin bundle-like structures. {ECO:0000250 UniProtKB:Q7TS73}.

Gene Ontology (GO) - Cellular Components for ZNF664-FAM101A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with ZNF664-FAM101A: view

No data available for Subcellular locations from COMPARTMENTS for ZNF664-FAM101A Gene

Pathways for ZNF664-FAM101A Gene

SuperPathways for ZNF664-FAM101A Gene

No Data Available

Interacting Proteins for ZNF664-FAM101A Gene

Selected Interacting proteins: Q6ZTI6-F101A_HUMAN for ZNF664-FAM101A Gene via UniProtKB I2D

Gene Ontology (GO) - Biological Process for ZNF664-FAM101A Gene


No data available for Pathways by source for ZNF664-FAM101A Gene

Transcripts for ZNF664-FAM101A Gene

mRNA/cDNA for ZNF664-FAM101A Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF664-FAM101A Gene

Protein FAM101A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF664-FAM101A Gene

No ASD Table

Relevant External Links for ZNF664-FAM101A Gene

GeneLoc Exon Structure for

Expression for ZNF664-FAM101A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ZNF664-FAM101A Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (22.8), Fetal gut (22.1), Stomach (13.5), and Urine (10.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF664-FAM101A Gene

SOURCE GeneReport for Unigene cluster for ZNF664-FAM101A Gene Hs.432901

genes like me logo Genes that share expressions with ZNF664-FAM101A: view

Expression partners for ZNF664-FAM101A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF664-FAM101A Gene

Orthologs for ZNF664-FAM101A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF664-FAM101A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM101A 35
  • 88.64 (n)
  • 88.15 (a)
FAM101A 36
  • 79 (a)
(Canis familiaris)
Mammalia FAM101A 35
  • 88.47 (n)
  • 86.47 (a)
FAM101A 36
  • 86 (a)
(Mus musculus)
Mammalia Fam101a 35
  • 80.74 (n)
  • 75.56 (a)
Fam101a 16
Fam101a 36
  • 50 (a)
(Pan troglodytes)
Mammalia FAM101A 35
  • 97.78 (n)
  • 97.78 (a)
FAM101A 36
  • 61 (a)
(Rattus norvegicus)
Mammalia Fam101a 35
  • 78.52 (n)
  • 77.78 (a)
(Monodelphis domestica)
Mammalia FAM101A 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia FAM101A 36
  • 43 (a)
(Gallus gallus)
Aves FAM101A 36
  • 42 (a)
(Anolis carolinensis)
Reptilia FAM101A 36
  • 40 (a)
(Danio rerio)
Actinopterygii fam101a 36
  • 32 (a)
Species with no ortholog for ZNF664-FAM101A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF664-FAM101A Gene

Gene Tree for ZNF664-FAM101A (if available)
Gene Tree for ZNF664-FAM101A (if available)

Paralogs for ZNF664-FAM101A Gene

Paralogs for ZNF664-FAM101A Gene

genes like me logo Genes that share paralogs with ZNF664-FAM101A: view

Variants for ZNF664-FAM101A Gene

Sequence variations from dbSNP and Humsavar for ZNF664-FAM101A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs367997 -- 124,129,853(+) actta(C/G)actaa intron-variant
rs371929 -- 124,141,017(-) GGAGA(A/G)GCCTT intron-variant
rs372201 -- 124,118,052(-) ACTTC(A/G)AGAAA intron-variant
rs372294 -- 124,118,746(+) TTTGC(C/T)ATGTT intron-variant
rs373132 -- 124,128,221(+) ctggg(C/T)aactg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF664-FAM101A Gene

Variant ID Type Subtype PubMed ID
esv2746515 CNV Deletion 23290073
nsv820508 CNV Duplication 20802225
nsv826535 CNV Gain 20364138
nsv819172 CNV Loss 19587683
esv22500 CNV Loss 19812545
nsv819689 CNV Loss 19587683
nsv899580 CNV Loss 21882294
nsv520633 CNV Gain 19592680
esv268914 CNV Insertion 20981092
nsv523233 CNV Loss 19592680
nsv518962 CNV Loss 19592680
esv2746516 CNV Deletion 23290073
esv2746517 CNV Deletion 23290073
esv4640 CNV Deletion 18987735
esv2746518 CNV Deletion 23290073
esv2675611 CNV Deletion 23128226
nsv53136 CNV Loss 16902084
esv2507408 CNV Insertion 19546169
nsv470320 CNV Loss 18288195
esv2672400 CNV Deletion 23128226
esv29133 CNV Loss 19812545
esv995708 CNV Deletion 20482838
nsv818930 CNV Gain 17921354
nsv899581 CNV Loss 21882294
dgv1499n71 CNV Loss 21882294
esv1202818 CNV Insertion 17803354
esv2746520 CNV Deletion 23290073
esv2746521 CNV Deletion 23290073
esv2669580 CNV Deletion 23128226
nsv53622 CNV Loss 16902084
nsv470322 CNV Loss 18288195

Relevant External Links for ZNF664-FAM101A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF664-FAM101A Gene

Disorders for ZNF664-FAM101A Gene

No disorders were found for ZNF664-FAM101A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF664-FAM101A Gene

Publications for ZNF664-FAM101A Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich T.M. … Kathiresan S. (Nature 2010) 3

Products for ZNF664-FAM101A Gene

Sources for ZNF664-FAM101A Gene

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