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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF664-FAM101A Gene

protein-coding   GIFtS: 16
GCID: GC12P124459

Protein FAM101A


  Search for ZNF664-FAM101A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Protein FAM101A2
ZNF664-FAM101A Readthrough2

External Ids:    Entrez Gene: 1005331832   

Export aliases for ZNF664-FAM101A gene to outside databases

Previous GC identifer: GC12U901544


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZNF664-FAM101A Gene:
This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein
664 (GeneID 144348) and hypothetical protein LOC144347 (GeneID 144347) genes on chromosome 12. The read-through
transcript produces a protein that shares sequence identity with the downstream hypothetical protein LOC144347
locus. (provided by RefSeq, Feb 2011)

GeneCards Summary for ZNF664-FAM101A Gene: 
ZNF664-FAM101A is a protein-coding gene. An important paralog of this gene is FAM101A.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009755.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF664-FAM101A
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF664-FAM101A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   

ZNF664-FAM101A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF664-FAM101A gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P124459:  view genomic region     (about GC identifiers)

Start:
124,457,762 bp from pter      End:
124,800,570 bp from pter
Size:
342,809 bases      Orientation:
plus strand
ZNF664-FAM101A has overlapping exons with:
FAM101A

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB: --
ZNF664-FAM101A Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
REFSEQ proteins: NP_001191228.1  
Human Recombinant Protein Products for ZNF664-FAM101A: 
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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF664-FAM101A

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
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Search CenterWatch for drugs/clinical trials and news about ZNF664-FAM101A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZNF664-FAM101A gene: 
NM_001204299.1  

Unigene Cluster for ZNF664-FAM101A:

Protein FAM101A
Hs.432901  [show with all ESTs]
Unigene Representative Sequence: NM_001204299
miRNA
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Additional mRNA sequence: 

AK074545.1 AK126577.1 BC026875.1 BC042102.1 BC067283.1 BC085606.1 BC141805.1 

6 DOTS entries:

DT.99964166  DT.312376  DT.101981274  DT.100780729  DT.100780730  DT.100728229 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --


ZNF664-FAM101A expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/10 selected tissues (see all 10) fully expand
 
 Bone (Muscoskeletal System)    fully expand to see all 2 entries
         Zeugopod Growth Plate
         sensory organ/ear/inner ear   
 
 Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
         sensory organ/nose/nasal septum   
 
 Epiblast (Early Embryonic Tissues)    fully expand to see all 2 entries
         Epiblast Stem Cell line 5
 
 Nose (Sensory Organs)
         sensory organ/nose/nasal septum   
 
 Gonad
         Primordial Germ Cells Allantois

SOURCE GeneReport for Unigene cluster: Hs.432901
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZNF664-FAM101A gene from 3/7 species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fam101a1 , 5 family with sequence similarity 101, member A1, 5 80.74(n)1
75.56(a)1
  5 (63.95 cM)5
731211  NM_028443.21  NP_082719.11 
 1250034475 
chicken
(Gallus gallus)
Aves FAM101A1 family with sequence similarity 101, member A 70.37(n)
65.93(a)
  771797  XM_001235027.2  XP_001235028.2 
zebrafish
(Danio rerio)
Actinopterygii fam101a1 family with sequence similarity 101, member A 63.05(n)
54.26(a)
  368489  NM_001007031.2  NP_001007032.1 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for ZNF664-FAM101A gene
FAM101A  

ZNF664-FAM101A for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/5772 SNPs in ZNF664-FAM101A are shown (see all 5772)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1116992111,2
C--121564778(+) ATTTAGTGTGTG 
 TGTGT
/-
GTGTG
1 -- int11Minor allele frequency- -:0.50CSA 2
rs1426215861,2
C--124500561(+) TGTGCC/TGCAGT 1 -- int10--------
rs73015471,2
C,F,A--124500676(+) GTGGGG/AGGTGG 1 -- int14Minor allele frequency- A:0.35NA WA 124
rs106061851,2
C--124500723(+) TGGTG-/AATCTGC 1 -- int11Minor allele frequency- AA:0.00CSA 2
rs1815496861,2
--124500885(+) GGGCAC/GAGCTC 1 -- int10--------
rs1505864861,2
--124500909(+) AGAAAC/TTGAAG 1 -- int10--------
rs761275171,2
C,F--124500911(+) AAATTG/AAAGAG 1 -- int11Minor allele frequency- A:0.02WA 118
rs1862059991,2
--124500953(+) GATTCC/TTTCCA 1 -- int10--------
rs123104081,2
C,F,H--124500994(+) AAAATT/GTTTGA 1 -- int16Minor allele frequency- G:0.05NS EA WA 474
rs734094281,2
C,F--124501144(+) ACAGGG/TCAAGA 1 -- int13Minor allele frequency- T:0.38WA 122

HapMap Linkage Disequilibrium report for ZNF664-FAM101A (124457762 - 124707762 bp, first 250kb of ZNF664-FAM101A)

Structural Variations
     Database of Genomic Variants (DGV) 10/31 variations for ZNF664-FAM101A (see all 31):    About this table     
Variant IDTypeSubtypePubMed ID
esv2675611CNV Deletion23128226
esv2746517CNV Deletion23290073
esv995708CNV Deletion20482838
esv2746515CNV Deletion23290073
esv2746520CNV Deletion23290073
esv2746518CNV Deletion23290073
esv2746516CNV Deletion23290073
esv2746521CNV Deletion23290073
esv2669580CNV Deletion23128226
esv2672400CNV Deletion23128226

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ZNF664-FAM101A gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF664-FAM101A)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Preliminary evidence of genetic determinants of adipon ectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet N etwork. (PubMed id 23149075)1 Aslibekyan S....Arnett D.K. (2012)
  2. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
  4. Biological, clinical and population relevance of 95 l oci for blood lipids. (PubMed id 20686565)1 Teslovich T.M....Kathiresan S. (2010)
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  6. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1 Scherer S.E.... Gibbs R.A. (2006)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1 Gerhard D.S....Malek J. (2004)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 100533183 euGenes: HUgn100533183

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
  --

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for ZNF664-FAM101A gene:
Search GeneIP for patents involving ZNF664-FAM101A

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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 inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF664-FAM101A
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF664-FAM101A
Customized:
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Customized transgenic rodents for:
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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