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Aliases for ZNF664 Gene

Aliases for ZNF664 Gene

  • Zinc Finger Protein 664 2 3 5
  • Zinc Finger Protein 176 2 3 4
  • Zinc Finger Protein From Organ Of Corti 3 4
  • ZFOC1 3 4
  • Zinc Finger Organ Of Corti 1 3
  • Organ Of Corti 1 2
  • Zinc Finger 2
  • ZNF176 3
  • ZNF196 4

External Ids for ZNF664 Gene

Previous HGNC Symbols for ZNF664 Gene

  • ZNF176

Previous GeneCards Identifiers for ZNF664 Gene

  • GC12P122983
  • GC12P124457
  • GC12P121419

Summaries for ZNF664 Gene

GeneCards Summary for ZNF664 Gene

ZNF664 (Zinc Finger Protein 664) is a Protein Coding gene. Diseases associated with ZNF664 include clubfoot. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF229.

UniProtKB/Swiss-Prot for ZNF664 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF664 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF664 Gene

Genomics for ZNF664 Gene

Regulatory Elements for ZNF664 Gene

Promoters for ZNF664 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF664 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF664 Gene

Chromosome:
12
Start:
123,971,845 bp from pter
End:
124,015,439 bp from pter
Size:
43,595 bases
Orientation:
Plus strand

Genomic View for ZNF664 Gene

Genes around ZNF664 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF664 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF664 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF664 Gene

Proteins for ZNF664 Gene

  • Protein details for ZNF664 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N3J9-ZN664_HUMAN
    Recommended name:
    Zinc finger protein 664
    Protein Accession:
    Q8N3J9
    Secondary Accessions:
    • B3KP97
    • Q15914
    • Q3ZCQ7

    Protein attributes for ZNF664 Gene

    Size:
    261 amino acids
    Molecular mass:
    30284 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF664 Gene

Proteomics data for ZNF664 Gene at MOPED

Post-translational modifications for ZNF664 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF664 Gene

No data available for DME Specific Peptides for ZNF664 Gene

Domains & Families for ZNF664 Gene

Gene Families for ZNF664 Gene

Protein Domains for ZNF664 Gene

Suggested Antigen Peptide Sequences for ZNF664 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N3J9

UniProtKB/Swiss-Prot:

ZN664_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF664: view

Function for ZNF664 Gene

Molecular function for ZNF664 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF664 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
genes like me logo Genes that share ontologies with ZNF664: view
genes like me logo Genes that share phenotypes with ZNF664: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF664 Gene

Localization for ZNF664 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF664 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF664 Gene COMPARTMENTS Subcellular localization image for ZNF664 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF664 Gene

Pathways & Interactions for ZNF664 Gene

SuperPathways for ZNF664 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF664: view

Pathways by source for ZNF664 Gene

2 Reactome pathways for ZNF664 Gene

Interacting Proteins for ZNF664 Gene

Gene Ontology (GO) - Biological Process for ZNF664 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF664: view

No data available for SIGNOR curated interactions for ZNF664 Gene

Drugs & Compounds for ZNF664 Gene

No Compound Related Data Available

Transcripts for ZNF664 Gene

Unigene Clusters for ZNF664 Gene

Zinc finger protein 664:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF664 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d · 12e · 12f · 12g
SP1: - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - - - - - -
SP4: - - - - - - - - -
SP5: - - - - - - -
SP6: - - - - - - - -
SP7: - - - - - - - -
SP8: - - - -
SP9: - - - - - - - - -
SP10: - - - - -
SP11:
SP12:

Relevant External Links for ZNF664 Gene

GeneLoc Exon Structure for
ZNF664
ECgene alternative splicing isoforms for
ZNF664

Expression for ZNF664 Gene

mRNA expression in normal human tissues for ZNF664 Gene

Protein differential expression in normal tissues from HIPED for ZNF664 Gene

This gene is overexpressed in Retina (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF664 Gene



SOURCE GeneReport for Unigene cluster for ZNF664 Gene Hs.524828

genes like me logo Genes that share expression patterns with ZNF664: view

Protein tissue co-expression partners for ZNF664 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF664 Gene

Orthologs for ZNF664 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF664 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF664 35
  • 99.74 (n)
  • 100 (a)
ZNF664 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF664 36
  • 100 (a)
OneToOne
ZNF664 35
  • 93.1 (n)
  • 100 (a)
dog
(Canis familiaris)
Mammalia ZNF664 35
  • 95.15 (n)
  • 100 (a)
ZNF664 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp664 16
Zfp664 36
  • 100 (a)
OneToOne
Zfp664 35
  • 90.93 (n)
  • 100 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 21 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC100911699 35
  • 91.53 (n)
  • 100 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX276122.1 36
  • 39 (a)
ManyToMany
BX324003.4 36
  • 40 (a)
ManyToMany
BX511066.4 36
  • 40 (a)
ManyToMany
BX537137.1 36
  • 39 (a)
ManyToMany
BX548067.3 36
  • 40 (a)
ManyToMany
BX649556.2 36
  • 54 (a)
ManyToMany
BX842593.1 36
  • 37 (a)
ManyToMany
BX901892.1 36
  • 40 (a)
ManyToMany
BX927193.1 36
  • 40 (a)
ManyToMany
BX950868.2 36
  • 40 (a)
ManyToMany
CABZ01001466.1 36
  • 39 (a)
ManyToMany
CABZ01017733.1 36
  • 33 (a)
ManyToMany
CABZ01028403.3 36
  • 39 (a)
ManyToMany
CR388052.2 36
  • 44 (a)
ManyToMany
CR759907.4 36
  • 39 (a)
ManyToMany
CU138542.1 36
  • 33 (a)
ManyToMany
si:ch211-178j18.2 36
  • 43 (a)
ManyToMany
si:ch211-208f21.2 36
  • 40 (a)
ManyToMany
si:ch211-209j12.3 36
  • 39 (a)
ManyToMany
si:ch211-231i17.4 36
  • 40 (a)
ManyToMany
si:ch211-79k12.2 36
  • 18 (a)
ManyToMany
si:dkey-146c18.5 36
  • 41 (a)
ManyToMany
si:dkey-156j15.1 36
  • 38 (a)
ManyToMany
si:dkey-264f17.4 36
  • 31 (a)
ManyToMany
si:dkey-285e18.6 36
  • 37 (a)
ManyToMany
si:dkey-28i19.1 36
  • 37 (a)
ManyToMany
si:dkey-3p4.8 36
  • 40 (a)
ManyToMany
si:dkey-7j22.4 36
  • 38 (a)
ManyToMany
zgc:173619 36
  • 40 (a)
ManyToMany
zgc:173619 36
  • 39 (a)
ManyToMany
zgc:173620 36
  • 39 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG1832 36
  • 18 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea eor-1 36
  • 8 (a)
OneToMany
Species with no ortholog for ZNF664:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF664 Gene

ENSEMBL:
Gene Tree for ZNF664 (if available)
TreeFam:
Gene Tree for ZNF664 (if available)

Paralogs for ZNF664 Gene

(583) SIMAP similar genes for ZNF664 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF664: view

Variants for ZNF664 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF664 Gene

Variant ID Type Subtype PubMed ID
esv2746515 CNV Deletion 23290073
nsv820508 CNV Duplication 20802225
nsv826535 CNV Gain 20364138
nsv819172 CNV Loss 19587683
esv22500 CNV Loss 19812545
nsv819689 CNV Loss 19587683
nsv899580 CNV Loss 21882294

Variation tolerance for ZNF664 Gene

Residual Variation Intolerance Score: 45.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.45; 64.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF664 Gene

HapMap Linkage Disequilibrium report
ZNF664
Human Gene Mutation Database (HGMD)
ZNF664

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZNF664 Gene

Disorders for ZNF664 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF664 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
clubfoot
  • congenital clubfoot
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZNF664

Genetic Association Database (GAD)
ZNF664
Human Genome Epidemiology (HuGE) Navigator
ZNF664
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF664
genes like me logo Genes that share disorders with ZNF664: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF664 Gene

Publications for ZNF664 Gene

  1. Exome sequencing identifies ZNF644 mutations in high myopia. (PMID: 21695231) Shi Y. … Yang Z. (PLoS Genet. 2011) 2 3 67
  2. Genome-wide association study identifies new disease loci for isolated clubfoot. (PMID: 24667120) Zhang T.X. … Gurnett C.A. (J. Med. Genet. 2014) 3
  3. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. (PMID: 24105470) Wu Y. … Tai E.S. (Hum. Mol. Genet. 2014) 3
  4. Discovery and refinement of loci associated with lipid levels. (PMID: 24097068) . … Abecasis G.R. (Nat. Genet. 2013) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for ZNF664 Gene

Sources for ZNF664 Gene

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