ZNF662 Gene
protein-coding GIFtS: 44
GCID: GC03P042947
|
|
zinc finger protein 662
| |
Aliases
for ZNF662 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6621 2 | | FLJ458801 |
Export aliases for ZNF662 gene to outside databasesPrevious GC identifer: GC03P042923 |
Summaries
for ZNF662 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN662_HUMAN, Q6ZS27Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF662 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF662 gene promoter:
HEN1 ATF-2 Pax-2 Pax-2a c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF662
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF662 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p22.1 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p22.1ZNF662 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P042947: view genomic region
(about GC identifiers)
Start:
|
42,947,223 bp from pter |
End:
|
42,960,825 bp from pter |
Size:
|
13,603 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF662 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN662_HUMAN, Q6ZS27 (See
protein sequence)Recommended Name: Zinc finger protein 662 Size: 426 amino acids; 48496 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q6ZNF8 Q6ZQW8Alternative splicing: 2 isoforms: Q6ZS27-1 Q6ZS27-2 Explore the universe of human proteins at neXtProt for ZNF662: NX_Q6ZS27
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZS27
ZNF662 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (2 alternative transcripts):
NP_001128128.1 NP_997287.2
ENSEMBL proteins: ENSP00000405047 ENSP00000329264 ENSP00000408945 ENSP00000446208 Reactome Protein details: Q6ZS27
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF662 for ontologies About GeneDecksing
ZNF662 Antibody Products:
Assay Products for ZNF662: |
Protein
Domains /
Families
for ZNF662 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF662 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZS27ProtoNet protein and cluster: Q6ZS27 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN662_HUMAN, Q6ZS27Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 8 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF662 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN662_HUMAN, Q6ZS27Function: May be involved in transcriptional regulation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF662 (NM_001134656) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF662 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF662 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF662 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF662 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF662 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF662
ZNF662 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF662
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF662 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF662 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF662
Search CenterWatch for drugs/clinical trials and news about ZNF662 / ZN662
|
Transcripts
for ZNF662 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF662 gene (2 alternative transcripts): NM_001134656.1 NM_207404.3 Unigene Cluster for ZNF662: Zinc finger protein 662 Hs.720173 [show with all ESTs]Unigene Representative Sequence: NM_2074046 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000440367 ENST00000328199 ENST00000475386 ENST00000422021 ENST00000430067
ENST00000541208(uc003cmi.2 uc003cmk.2 uc003cmj.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF662 (NM_001134656) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF662 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF662 |
Additional cDNA sequence: AK054699.1 AK090666.1 AK090754.1 AK127779.1 AK131235.1 BC128085.1 7 DOTS entries: DT.105475 DT.97809598 DT.99936369 DT.211566 DT.91970043 DT.40215298 DT.97820731 24/189 AceView cDNA sequences (see all 189): AI700588 CR610139 BX116130 AI570427 BQ013601 NM_001296 AW771170 BM674860 AI306141 AA424410 BC018716 AI870497 AA758769 AK054699 W61299 BC041820 AI674985 AI565258 BU159134 BE669583 AA399554 BE466204 BC011631 BC008816
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF662 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for ZNF662
|
Expression
for ZNF662 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF662 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAGGACTGA
About this image
Genevestigator expression for ZNF662
SOURCE GeneReport for Unigene cluster: Hs.720173
SABiosciences Custom PCR Arrays for ZNF662
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF662
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF662 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF662 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF662 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF662 |
Orthologs
for ZNF662 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF662 gene from 2/6 species (see all 6) About this table
ENSEMBL Gene Tree for ZNF662 (if available)
TreeFam Gene Tree for ZNF662 (if available) |
Paralogs
for ZNF662 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF662 gene
- ZNF6212 ZNF192 ZNF6202 ENSG000002616112 ZNF6192
18/513 SIMAP similar genes for ZNF662 using alignment to 4 protein entries: ZN662_HUMAN (see all proteins)
(see all similar genes):ZNF78L1 HZF36 ZNF232 ZNF286B ZNF818P ZNF826P
ZNF345 DKFZp313M0722 DKFZp547L155 ZFP41 ZNF16 ZNF551
ZNF808 GLI4 ZKSCAN1 ZNF267 ZNF300P1 ZNF519
ZNF662 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF662 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF662 (42947223 - 42960825 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF662: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF662 |
|
Disorders
/ Diseases
for ZNF662 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF662 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF662 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF662) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF662 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF662 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF662 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF662 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF662 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF662 gene:
Search GeneIP for patents involving ZNF662
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF662 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF662 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF662 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF662 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF662 | | OriGene 3'-UTR Clone for ZNF662 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF662 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF662 | | OriGene Custom Protein Services for ZNF662 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF662 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF662 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF662 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF662 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF662 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF662 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF662 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF662 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF662 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF662 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF662 |
|
|
|
|
