Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF660 Gene

Aliases for ZNF660 Gene

  • Zinc Finger Protein 660 2 3 5

External Ids for ZNF660 Gene

Previous GeneCards Identifiers for ZNF660 Gene

  • GC03P044602
  • GC03P044619
  • GC03P044600
  • GC03P044686
  • GC03P044810
  • GC03P044848
  • GC03P044917

Summaries for ZNF660 Gene

GeneCards Summary for ZNF660 Gene

ZNF660 (Zinc Finger Protein 660) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF35.

UniProtKB/Swiss-Prot for ZNF660 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF660 Gene

Genomics for ZNF660 Gene

Regulatory Elements for ZNF660 Gene

Enhancers for ZNF660 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G044438 1.6 Ensembl ENCODE dbSUPER 48.6 -138.0 -138036 3.5 HDGF PKNOX1 FOXA2 MLX CREB3L1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF660 ZNF197 LINC00694 GC03M044441
GH03G044468 1.3 Ensembl ENCODE 46 -109.1 -109146 1.0 HDGF ARNT ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 ZNF207 FOS ZNF660 ZNF197 ZNF445 GC03M044441
GH03G044882 1.8 FANTOM5 Ensembl ENCODE dbSUPER 28.5 +307.1 307108 5.2 SIN3A TCF12 GLIS2 ZNF766 GATA2 FOS TSHZ1 ZNF518A MAFF SMARCA4 ZNF660 ZKSCAN7 KIAA1143 TGM4 ZNF501 ZNF197 ENSG00000235845
GH03G044509 1 ENCODE 50.7 -67.5 -67524 2.6 HDGF ATF1 ARNT WRNIP1 ARID4B SIN3A ZNF2 ZNF48 YY1 TCF12 ZNF660 ZNF197 ZNF852 EI24P3
GH03G044355 1.1 Ensembl ENCODE 45 -222.5 -222496 1.3 PKNOX1 ATF1 TBL1XR1 RFX5 YY1 TCF12 FOS JUNB CEBPB MEF2D ZNF660 ZNF445 ZNF197 LOC105377055 LINC01988
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF660 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF660 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000151590 151 1201 FOXA2 SAP130 ARID4B MAX SIN3A RBBP5 ETS1 POLR2A ZNF143 ZNF207

Genomic Location for ZNF660 Gene

Chromosome:
3
Start:
44,578,223 bp from pter
End:
44,599,699 bp from pter
Size:
21,477 bases
Orientation:
Plus strand

Genomic View for ZNF660 Gene

Genes around ZNF660 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF660 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF660 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF660 Gene

Proteins for ZNF660 Gene

  • Protein details for ZNF660 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AZW8-ZN660_HUMAN
    Recommended name:
    Zinc finger protein 660
    Protein Accession:
    Q6AZW8
    Secondary Accessions:
    • Q7Z331
    • Q8N9M8

    Protein attributes for ZNF660 Gene

    Size:
    331 amino acids
    Molecular mass:
    38270 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF660 Gene

Post-translational modifications for ZNF660 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF660 Gene

No data available for DME Specific Peptides for ZNF660 Gene

Domains & Families for ZNF660 Gene

Gene Families for ZNF660 Gene

Protein Domains for ZNF660 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF660 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6AZW8

UniProtKB/Swiss-Prot:

ZN660_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF660: view

Function for ZNF660 Gene

Molecular function for ZNF660 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF660: view
genes like me logo Genes that share phenotypes with ZNF660: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF660 Gene

Localization for ZNF660 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF660 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF660 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF660: view

Pathways & Interactions for ZNF660 Gene

SuperPathways for ZNF660 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF660: view

Pathways by source for ZNF660 Gene

2 Reactome pathways for ZNF660 Gene

Interacting Proteins for ZNF660 Gene

Gene Ontology (GO) - Biological Process for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF660: view

No data available for SIGNOR curated interactions for ZNF660 Gene

Drugs & Compounds for ZNF660 Gene

No Compound Related Data Available

Transcripts for ZNF660 Gene

mRNA/cDNA for ZNF660 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF660 Gene

Zinc finger protein 660:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF660 Gene

No ASD Table

Relevant External Links for ZNF660 Gene

GeneLoc Exon Structure for
ZNF660
ECgene alternative splicing isoforms for
ZNF660

Expression for ZNF660 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF660 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF660 Gene:

ZNF660

SOURCE GeneReport for Unigene cluster for ZNF660 Gene:

Hs.733134

Evidence on tissue expression from TISSUES for ZNF660 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF660: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF660 Gene

Orthologs for ZNF660 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF660 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF660 34 35
  • 99.7 (n)
dog
(Canis familiaris)
Mammalia ZNF660 34
  • 92.35 (n)
-- 35
  • 42 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia LOC102639251 34
  • 85.35 (n)
Zscan26 35
  • 36 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC102551231 34
  • 81.82 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 26 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii BX890548.2 35
  • 39 (a)
ManyToMany
BX005448.1 35
  • 38 (a)
ManyToMany
zgc:174700 35
  • 38 (a)
ManyToMany
gb:am422109 35
  • 38 (a)
ManyToMany
BX004879.1 35
  • 37 (a)
ManyToMany
si:ch211-283l16.1 35
  • 37 (a)
ManyToMany
si:dkey-56m15.3 35
  • 37 (a)
ManyToMany
CABZ01008480.1 35
  • 36 (a)
ManyToMany
CT573263.3 35
  • 36 (a)
ManyToMany
si:dkey-22h13.2 35
  • 36 (a)
ManyToMany
CR293532.1 35
  • 35 (a)
ManyToMany
si:ch211-226o13.2 35
  • 35 (a)
ManyToMany
si:dkey-237m9.1 35
  • 35 (a)
ManyToMany
si:dkey-54j5.2 35
  • 35 (a)
ManyToMany
zgc:173714 35
  • 34 (a)
ManyToMany
zgc:174694 35
  • 34 (a)
ManyToMany
si:dkey-16b10.2 35
  • 32 (a)
ManyToMany
BX005448.2 35
  • 29 (a)
ManyToMany
Species where no ortholog for ZNF660 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF660 Gene

ENSEMBL:
Gene Tree for ZNF660 (if available)
TreeFam:
Gene Tree for ZNF660 (if available)

Paralogs for ZNF660 Gene

Paralogs for ZNF660 Gene

(535) SIMAP similar genes for ZNF660 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF660: view

Variants for ZNF660 Gene

Sequence variations from dbSNP and Humsavar for ZNF660 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs587776368 untested 44,594,914(+) TTCAT(A/C/T)GTAGA reference, missense
rs1000001117 -- 44,593,654(+) AGGTT(C/G)CAGTG intron-variant
rs1000096946 -- 44,593,409(+) GCCTG(A/C)CATTA intron-variant
rs1000144545 -- 44,587,720(+) TTCTC(C/T)CTACC intron-variant
rs1000231525 -- 44,586,555(+) CTGAG(A/G)GTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF660 Gene

Variant ID Type Subtype PubMed ID
nsv3790 CNV insertion 18451855

Variation tolerance for ZNF660 Gene

Residual Variation Intolerance Score: 58.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF660 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF660

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF660 Gene

Disorders for ZNF660 Gene

Relevant External Links for ZNF660

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF660

No disorders were found for ZNF660 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF660 Gene

Publications for ZNF660 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4 64
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF660 Gene

Sources for ZNF660 Gene

Content
Loading form....