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Aliases for ZNF660 Gene

Aliases for ZNF660 Gene

  • Zinc Finger Protein 660 2 3

External Ids for ZNF660 Gene

Previous GeneCards Identifiers for ZNF660 Gene

  • GC03P044602
  • GC03P044619

Summaries for ZNF660 Gene

GeneCards Summary for ZNF660 Gene

ZNF660 (Zinc Finger Protein 660) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF35.

UniProtKB/Swiss-Prot for ZNF660 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF660 Gene

Genomics for ZNF660 Gene

Regulatory Elements for ZNF660 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF660 Gene

Start:
44,578,223 bp from pter
End:
44,599,694 bp from pter
Size:
21,472 bases
Orientation:
Plus strand

Genomic View for ZNF660 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF660 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF660 Gene

Proteins for ZNF660 Gene

  • Protein details for ZNF660 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AZW8-ZN660_HUMAN
    Recommended name:
    Zinc finger protein 660
    Protein Accession:
    Q6AZW8
    Secondary Accessions:
    • Q7Z331
    • Q8N9M8

    Protein attributes for ZNF660 Gene

    Size:
    331 amino acids
    Molecular mass:
    38270 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF660 Gene

Proteomics data for ZNF660 Gene at MOPED

Post-translational modifications for ZNF660 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF660 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF660 Gene

Domains for ZNF660 Gene

Gene Families for ZNF660 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF660 Gene

Suggested Antigen Peptide Sequences for ZNF660 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6AZW8

UniProtKB/Swiss-Prot:

ZN660_HUMAN :
  • Q6AZW8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF660: view

Function for ZNF660 Gene

Molecular function for ZNF660 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF660: view

Phenotypes for ZNF660 Gene

GenomeRNAi human phenotypes for ZNF660:
genes like me logo Genes that share phenotypes with ZNF660: view

Animal Model Products

CRISPR Products

miRNA for ZNF660 Gene

miRTarBase miRNAs that target ZNF660

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF660 Gene

Localization for ZNF660 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF660 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF660 Gene COMPARTMENTS Subcellular localization image for ZNF660 gene
Compartment Confidence
nucleus 4
cytosol 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF660: view

Pathways for ZNF660 Gene

SuperPathways for ZNF660 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF660: view

Pathways by source for ZNF660 Gene

2 Reactome pathways for ZNF660 Gene

Interacting Proteins for ZNF660 Gene

Gene Ontology (GO) - Biological Process for ZNF660 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF660: view

Transcripts for ZNF660 Gene

mRNA/cDNA for ZNF660 Gene

(10) Selected AceView cDNA sequences:
(7) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF660 Gene

Zinc finger protein 660:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF660

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF660 Gene

No ASD Table

Relevant External Links for ZNF660 Gene

GeneLoc Exon Structure for
ZNF660
ECgene alternative splicing isoforms for
ZNF660

Expression for ZNF660 Gene

mRNA expression in normal human tissues for ZNF660 Gene

SOURCE GeneReport for Unigene cluster for ZNF660 Gene Hs.733134

genes like me logo Genes that share expressions with ZNF660: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF660 Gene

Orthologs for ZNF660 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF660 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF660 35
  • 99.7 (n)
  • 99.4 (a)
ZNF660 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 26 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 42 (a)
ManyToMany
ZNF660 35
  • 92.35 (n)
  • 94.56 (a)
mouse
(Mus musculus)
Mammalia LOC102639251 35
  • 85.35 (n)
  • 87.88 (a)
Zscan26 36
  • 36 (a)
ManyToMany
9 16
rat
(Rattus norvegicus)
Mammalia LOC102551231 35
  • 81.82 (n)
  • 87.27 (a)
zebrafish
(Danio rerio)
Actinopterygii BX004879.1 36
  • 37 (a)
ManyToMany
BX005448.1 36
  • 38 (a)
ManyToMany
BX005448.2 36
  • 29 (a)
ManyToMany
BX890548.2 36
  • 39 (a)
ManyToMany
CABZ01008480.1 36
  • 36 (a)
ManyToMany
CR293532.1 36
  • 35 (a)
ManyToMany
CT573263.3 36
  • 36 (a)
ManyToMany
gb:am422109 36
  • 38 (a)
ManyToMany
si:ch211-226o13.2 36
  • 35 (a)
ManyToMany
si:ch211-283l16.1 36
  • 37 (a)
ManyToMany
si:dkey-16b10.2 36
  • 32 (a)
ManyToMany
si:dkey-22h13.2 36
  • 36 (a)
ManyToMany
si:dkey-237m9.1 36
  • 35 (a)
ManyToMany
si:dkey-54j5.2 36
  • 35 (a)
ManyToMany
si:dkey-56m15.3 36
  • 37 (a)
ManyToMany
zgc:173714 36
  • 34 (a)
ManyToMany
zgc:174694 36
  • 34 (a)
ManyToMany
zgc:174700 36
  • 38 (a)
ManyToMany
Species with no ortholog for ZNF660:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF660 Gene

ENSEMBL:
Gene Tree for ZNF660 (if available)
TreeFam:
Gene Tree for ZNF660 (if available)

Paralogs for ZNF660 Gene

Paralogs for ZNF660 Gene

Selected SIMAP similar genes for ZNF660 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF660: view

Variants for ZNF660 Gene

Sequence variations from dbSNP and Humsavar for ZNF660 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs939649 -- 44,590,720(-) TTTCT(A/C)ATCTT intron-variant, utr-variant-5-prime
rs4414892 -- 44,587,657(+) TCCTC(C/G)TCAGC intron-variant
rs6441858 -- 44,584,132(+) Aaagt(C/T)agatc upstream-variant-2KB
rs6441859 -- 44,584,405(+) TTACT(A/G)CTACG upstream-variant-2KB
rs7618824 -- 44,597,585(+) ATTTG(C/T)AGCAT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF660 Gene

Variant ID Type Subtype PubMed ID
nsv3790 CNV Insertion 18451855

Relevant External Links for ZNF660 Gene

HapMap Linkage Disequilibrium report
ZNF660

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF660 Gene

Disorders for ZNF660 Gene

No disorders were found for ZNF660 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF660 Gene

Publications for ZNF660 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4

Products for ZNF660 Gene

Sources for ZNF660 Gene

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