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Aliases for ZNF66 Gene

Aliases for ZNF66 Gene

  • Zinc Finger Protein 66 2 3
  • Zinc Finger Protein 66, Pseudogene 2 3
  • ZNF66P 3 4
  • Zinc Finger Protein 486 Pseudogene 3
  • Zinc Finger Protein 66 Pseudogene 4

External Ids for ZNF66 Gene

Previous HGNC Symbols for ZNF66 Gene

  • ZNF66P

Previous GeneCards Identifiers for ZNF66 Gene

  • GC19U990108
  • GC19M020521
  • GC19P020751
  • GC19P020944

Summaries for ZNF66 Gene

GeneCards Summary for ZNF66 Gene

ZNF66 (Zinc Finger Protein 66) is a Pseudogene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF66 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF66 Gene

Genomics for ZNF66 Gene

Genomic Location for ZNF66 Gene

Chromosome:
19
Start:
20,776,270 bp from pter
End:
20,837,476 bp from pter
Size:
61,207 bases
Orientation:
Plus strand

Genomic View for ZNF66 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF66 Gene

No data available for Regulatory Elements for ZNF66 Gene

Proteins for ZNF66 Gene

  • Protein details for ZNF66 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN08-ZNF66_HUMAN
    Recommended name:
    Putative zinc finger protein 66
    Protein Accession:
    Q6ZN08
    Secondary Accessions:
    • I3L4P5
    • Q15939

    Protein attributes for ZNF66 Gene

    Size:
    573 amino acids
    Molecular mass:
    65874 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF66 Gene

Proteomics data for ZNF66 Gene at MOPED

Post-translational modifications for ZNF66 Gene

No Post-translational modifications

Other Protein References for ZNF66 Gene

No data available for DME Specific Peptides for ZNF66 Gene

Domains & Families for ZNF66 Gene

Protein Domains for ZNF66 Gene

Suggested Antigen Peptide Sequences for ZNF66 Gene

Graphical View of Domain Structure for InterPro Entry

Q6ZN08

UniProtKB/Swiss-Prot:

ZNF66_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF66: view

No data available for Gene Families for ZNF66 Gene

Function for ZNF66 Gene

Molecular function for ZNF66 Gene

GENATLAS Biochemistry:
zinc finger protein 66 (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF66: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF66 Gene

Localization for ZNF66 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF66 Gene

Gene Ontology (GO) - Cellular Components for ZNF66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF66: view

No data available for Subcellular locations from COMPARTMENTS for ZNF66 Gene

Pathways & Interactions for ZNF66 Gene

SuperPathways for ZNF66 Gene

No Data Available

Interacting Proteins for ZNF66 Gene

Gene Ontology (GO) - Biological Process for ZNF66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF66: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF66 Gene

Drugs & Compounds for ZNF66 Gene

No Compound Related Data Available

Transcripts for ZNF66 Gene

mRNA/cDNA for ZNF66 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF66 Gene

No ASD Table

Relevant External Links for ZNF66 Gene

GeneLoc Exon Structure for
ZNF66
ECgene alternative splicing isoforms for
ZNF66

Expression for ZNF66 Gene

mRNA expression in normal human tissues for ZNF66 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF66 Gene

This gene is overexpressed in Ovary (x4.0).

Protein differential expression in normal tissues from HIPED for ZNF66 Gene

This gene is overexpressed in Plasma (39.0), Monocytes (16.8), and Tlymphocyte (12.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF66 Gene



genes like me logo Genes that share expression patterns with ZNF66: view

Protein tissue co-expression partners for ZNF66 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF66 Gene

Orthologs for ZNF66 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF66 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 55 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 39 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp386 36
  • 36 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF66 36
  • 93 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 55 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
Species with no ortholog for ZNF66:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF66 Gene

ENSEMBL:
Gene Tree for ZNF66 (if available)
TreeFam:
Gene Tree for ZNF66 (if available)

Paralogs for ZNF66 Gene

(611) SIMAP similar genes for ZNF66 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF66 Gene

genes like me logo Genes that share paralogs with ZNF66: view

Variants for ZNF66 Gene

Variation tolerance for ZNF66 Gene

Gene Damage Index Score: 16.80; 97.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF66 Gene

HapMap Linkage Disequilibrium report
ZNF66

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for ZNF66 Gene

Disorders for ZNF66 Gene

Relevant External Links for ZNF66

Genetic Association Database (GAD)
ZNF66
Human Genome Epidemiology (HuGE) Navigator
ZNF66
genes like me logo Genes that share disorders with ZNF66: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF66 Gene

Publications for ZNF66 Gene

  1. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ZNF66 Gene

Sources for ZNF66 Gene

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