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Aliases for ZNF658 Gene

Aliases for ZNF658 Gene

  • Zinc Finger Protein 658 2 3

External Ids for ZNF658 Gene

Summaries for ZNF658 Gene

GeneCards Summary for ZNF658 Gene

ZNF658 (Zinc Finger Protein 658) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF658 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF658 Gene

Genomics for ZNF658 Gene

Genomic Location for ZNF658 Gene

Start:
66,856,426 bp from pter
End:
66,932,141 bp from pter
Size:
75,716 bases
Orientation:
Plus strand

Genomic View for ZNF658 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF658 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF658 Gene

No data available for Regulatory Elements for ZNF658 Gene

Proteins for ZNF658 Gene

  • Protein details for ZNF658 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TYW1-ZN658_HUMAN
    Recommended name:
    Zinc finger protein 658
    Protein Accession:
    Q5TYW1
    Secondary Accessions:
    • Q6PIP3
    • Q96M55
    • Q9H9S6
    • Q9UG02

    Protein attributes for ZNF658 Gene

    Size:
    1059 amino acids
    Molecular mass:
    122274 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH31626.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14145.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAB53677.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF658 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF658 Gene

Proteomics data for ZNF658 Gene at MOPED

Post-translational modifications for ZNF658 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF658 Gene

No data available for DME Specific Peptides for ZNF658 Gene

Domains for ZNF658 Gene

Gene Families for ZNF658 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF658 Gene

UniProtKB/Swiss-Prot:

ZN658_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q5TYW1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q5TYW1
Similarity:
  • Contains 24 C2H2-type zinc fingers.:
    • Q5TYW1
genes like me logo Genes that share domains with ZNF658: view

Function for ZNF658 Gene

Molecular function for ZNF658 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF658 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF658: view

Phenotypes for ZNF658 Gene

GenomeRNAi human phenotypes for ZNF658:
genes like me logo Genes that share phenotypes with ZNF658: view

miRNA for ZNF658 Gene

miRTarBase miRNAs that target ZNF658

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF658 Gene

Localization for ZNF658 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF658 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF658 Gene COMPARTMENTS Subcellular localization image for ZNF658 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF658 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF658: view

Pathways for ZNF658 Gene

SuperPathways for ZNF658 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF658: view

Pathways by source for ZNF658 Gene

2 Reactome pathways for ZNF658 Gene

Interacting Proteins for ZNF658 Gene

Gene Ontology (GO) - Biological Process for ZNF658 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF658: view

Transcripts for ZNF658 Gene

mRNA/cDNA for ZNF658 Gene

(4) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF658 Gene

Zinc finger protein 658:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF658 Gene

No ASD Table

Relevant External Links for ZNF658 Gene

GeneLoc Exon Structure for
ZNF658
ECgene alternative splicing isoforms for
ZNF658

Expression for ZNF658 Gene

mRNA expression in normal human tissues for ZNF658 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZNF658 Gene

SOURCE GeneReport for Unigene cluster for ZNF658 Gene Hs.522147

genes like me logo Genes that share expressions with ZNF658: view

Orthologs for ZNF658 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF658 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF658 36
  • 99.31 (n)
  • 98.58 (a)
dog
(Canis familiaris)
Mammalia ZNF658 36
  • 82.36 (n)
  • 72.22 (a)
mouse
(Mus musculus)
Mammalia Gm7145 36
  • 66.86 (n)
  • 58.51 (a)
rat
(Rattus norvegicus)
Mammalia LOC102553026 36
  • 60.45 (n)
  • 48.94 (a)
Species with no ortholog for ZNF658:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF658 Gene

ENSEMBL:
Gene Tree for ZNF658 (if available)
TreeFam:
Gene Tree for ZNF658 (if available)

Paralogs for ZNF658 Gene

Selected SIMAP similar genes for ZNF658 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF658: view

No data available for Paralogs for ZNF658 Gene

Variants for ZNF658 Gene

Sequence variations from dbSNP and Humsavar for ZNF658 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1060552 -- 66,920,774(+) AACAC(A/G)TAGTG utr-variant-3-prime
rs1064200 -- 66,920,566(+) TGCGG(A/G)AAAGC reference, synonymous-codon
rs1332419 -- 66,910,212(+) GTCAC(C/T)AATGA intron-variant
rs1332420 -- 66,910,256(+) TGTAC(A/G)AATAA intron-variant
rs1332424 -- 66,914,807(+) ATTTC(A/G)GTgta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF658 Gene

Variant ID Type Subtype PubMed ID
dgv8179n71 CNV Gain 21882294
essv9712 CNV CNV 17122850
dgv8183n71 CNV Gain 21882294
nsv893129 CNV Gain 21882294
nsv831560 CNV Gain 17160897
nsv893132 CNV Gain 21882294
nsv893133 CNV Gain+Loss 21882294
nsv893135 CNV Gain 21882294
dgv8185n71 CNV Gain 21882294
nsv831561 CNV Loss 17160897
dgv8186n71 CNV Gain 21882294
dgv8187n71 CNV Gain 21882294
nsv893142 CNV Loss 21882294
dgv8189n71 CNV Gain 21882294
nsv893154 CNV Gain 21882294
esv27810 CNV Gain 19812545
dgv1218n67 CNV Gain 20364138

Relevant External Links for ZNF658 Gene

HapMap Linkage Disequilibrium report
ZNF658

Disorders for ZNF658 Gene

No disorders were found for ZNF658 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF658 Gene

Publications for ZNF658 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. A whole genome screen for HIV restriction factors. (PMID: 22082156) Liu L. … McKnight A. (Retrovirology 2011) 3

Products for ZNF658 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF658
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF658
    • Block miRNA regulation of ZNF658 using miScript Target Protectors
    • antibodies-online proteins for ZNF658
    • antibodies-online antibodies for ZNF658
    • antibodies-online kits for ZNF658

    Sources for ZNF658 Gene

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