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Aliases for ZNF655 Gene

Aliases for ZNF655 Gene

  • Zinc Finger Protein 655 2 3 5
  • VIK 3 4
  • Vav-1 Interacting Kruppel-Like Protein 3
  • Vav-Interacting Krueppel-Like Protein 4
  • VIK-1 3

External Ids for ZNF655 Gene

Previous GeneCards Identifiers for ZNF655 Gene

  • GC07P098801
  • GC07P098993
  • GC07P099156
  • GC07P093793

Summaries for ZNF655 Gene

Entrez Gene Summary for ZNF655 Gene

  • This gene encodes a zinc finger protein. The zinc finger proteins are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF655 Gene

ZNF655 (Zinc Finger Protein 655) is a Protein Coding gene. Among its related pathways are RB in Cancer and Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ENSG00000272647.

UniProtKB/Swiss-Prot for ZNF655 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF655 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF655 Gene

Genomics for ZNF655 Gene

Regulatory Elements for ZNF655 Gene

Enhancers for ZNF655 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF655 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF655 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF655 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF655 Gene

Chromosome:
7
Start:
99,558,406 bp from pter
End:
99,576,453 bp from pter
Size:
18,048 bases
Orientation:
Plus strand

Genomic View for ZNF655 Gene

Genes around ZNF655 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF655 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF655 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF655 Gene

Proteins for ZNF655 Gene

  • Protein details for ZNF655 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N720-ZN655_HUMAN
    Recommended name:
    Zinc finger protein 655
    Protein Accession:
    Q8N720
    Secondary Accessions:
    • A4D291
    • A6NGD3
    • B4E3M4
    • B7Z9Q9
    • D6W5T4
    • Q8IV00
    • Q8TA89
    • Q96EZ3
    • Q9BQ85

    Protein attributes for ZNF655 Gene

    Size:
    491 amino acids
    Molecular mass:
    57407 Da
    Quaternary structure:
    • Interacts with VAV1 and CDK4.

    Alternative splice isoforms for ZNF655 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF655 Gene

Proteomics data for ZNF655 Gene at MOPED

Post-translational modifications for ZNF655 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF655 Gene

Domains & Families for ZNF655 Gene

Gene Families for ZNF655 Gene

Protein Domains for ZNF655 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N720

UniProtKB/Swiss-Prot:

ZN655_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF655: view

Function for ZNF655 Gene

Molecular function for ZNF655 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF655 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 15558030
genes like me logo Genes that share ontologies with ZNF655: view
genes like me logo Genes that share phenotypes with ZNF655: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF655 Gene

Localization for ZNF655 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF655 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF655 Gene COMPARTMENTS Subcellular localization image for ZNF655 gene
Compartment Confidence
nucleus 5
plasma membrane 3
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZNF655 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 15558030
genes like me logo Genes that share ontologies with ZNF655: view

Pathways & Interactions for ZNF655 Gene

genes like me logo Genes that share pathways with ZNF655: view

Pathways by source for ZNF655 Gene

2 BioSystems pathways for ZNF655 Gene
2 Reactome pathways for ZNF655 Gene

Gene Ontology (GO) - Biological Process for ZNF655 Gene

None

No data available for SIGNOR curated interactions for ZNF655 Gene

Drugs & Compounds for ZNF655 Gene

No Compound Related Data Available

Transcripts for ZNF655 Gene

Unigene Clusters for ZNF655 Gene

Zinc finger protein 655:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF655 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e ·
SP1: - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - -
SP6: - - - - -
SP7: - - - - - - - - - - - -
SP8: - - - - - - -
SP9: - - - - - - - - - - - - - -
SP10: - - - - - - - - - - - - - - - -
SP11: - - - - - - -
SP12: - - - - - - - - - -
SP13: - - - - - - - - - - - - -
SP14: - - - - - - - - - - - -
SP15: - - - - - - - - - - -
SP16: - - - - - - - - - - - - - - - -
SP17: - - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - -
SP19: - -
SP20: - - - - - - -
SP21: - - - - - - -
SP22: - - - - -
SP23:
SP24: - - - - -

ExUns: 7f · 7g · 7h ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d · 11e · 11f · 11g · 11h
SP1:
SP2:
SP3: - - - -
SP4: - - - - -
SP5: - - - - -
SP6:
SP7: - - - - -
SP8:
SP9: - - - - -
SP10: - - - - -
SP11:
SP12:
SP13: - - - - -
SP14: - - - - -
SP15:
SP16: - - - - - -
SP17: - - -
SP18: - - - - - -
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:

Relevant External Links for ZNF655 Gene

GeneLoc Exon Structure for
ZNF655
ECgene alternative splicing isoforms for
ZNF655

Expression for ZNF655 Gene

mRNA expression in normal human tissues for ZNF655 Gene

Protein differential expression in normal tissues from HIPED for ZNF655 Gene

This gene is overexpressed in Adipocyte (54.1) and Placenta (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF655 Gene



SOURCE GeneReport for Unigene cluster for ZNF655 Gene Hs.599798

genes like me logo Genes that share expression patterns with ZNF655: view

Protein tissue co-expression partners for ZNF655 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF655 Gene

Orthologs for ZNF655 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF655 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Zfp655 35
  • 85.71 (n)
  • 81.92 (a)
Zfp655 16
Zfp655 36
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp655 35
  • 85.64 (n)
  • 80.77 (a)
dog
(Canis familiaris)
Mammalia ZNF655 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 24 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF655 36
  • 100 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 29 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX927130.1 36
  • 24 (a)
OneToMany
Species with no ortholog for ZNF655:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF655 Gene

ENSEMBL:
Gene Tree for ZNF655 (if available)
TreeFam:
Gene Tree for ZNF655 (if available)

Paralogs for ZNF655 Gene

Paralogs for ZNF655 Gene

Pseudogenes.org Pseudogenes for ZNF655 Gene

genes like me logo Genes that share paralogs with ZNF655: view

Variants for ZNF655 Gene

Sequence variations from dbSNP and Humsavar for ZNF655 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs17853754 - 99,572,264(+) GAAGA(G/T)AACAA reference, missense
rs940335 -- 99,561,710(-) GCATG(C/G)CTTAT intron-variant
rs952319 -- 99,573,826(+) TCTTA(C/T)AAATG utr-variant-3-prime
rs1137418 -- 99,566,746(+) aaaga(A/G)ggtgt intron-variant
rs1273679 -- 99,572,715(+) AATGG(A/G)AGAGC reference, missense

Variation tolerance for ZNF655 Gene

Residual Variation Intolerance Score: 73.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.29; 53.11% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF655 Gene

Disorders for ZNF655 Gene

Relevant External Links for ZNF655

Genetic Association Database (GAD)
ZNF655
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF655

No disorders were found for ZNF655 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF655 Gene

Publications for ZNF655 Gene

  1. Characterization of VIK-1: a new Vav-interacting Kruppel-like protein. (PMID: 15558030) Houlard M. … Varin-Blank N. (Oncogene 2005) 2 3 4 67
  2. Zinc finger proteins: new insights into structural and functional diversity. (PMID: 11179890) Laity J.H. … Wright P.E. (Curr. Opin. Struct. Biol. 2001) 2 3
  3. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A. … Stelzl U. (Mol. Syst. Biol. 2015) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin S.Y. … Soranzo N. (Nat. Genet. 2014) 3

Products for ZNF655 Gene

Sources for ZNF655 Gene

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