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Aliases for ZNF654 Gene

Aliases for ZNF654 Gene

  • Zinc Finger Protein 654 2 3
  • Melanoma-Associated Antigen 4

External Ids for ZNF654 Gene

Previous GeneCards Identifiers for ZNF654 Gene

  • GC03P088271
  • GC03P088188

Summaries for ZNF654 Gene

GeneCards Summary for ZNF654 Gene

ZNF654 (Zinc Finger Protein 654) is a Protein Coding gene. An important paralog of this gene is RLF.

UniProtKB/Swiss-Prot for ZNF654 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF654 Gene

Genomics for ZNF654 Gene

Regulatory Elements for ZNF654 Gene

Genomic Location for ZNF654 Gene

Start:
88,059,244 bp from pter
End:
88,144,665 bp from pter
Size:
85,422 bases
Orientation:
Plus strand

Genomic View for ZNF654 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF654 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF654 Gene

Proteins for ZNF654 Gene

  • Protein details for ZNF654 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZM8-ZN654_HUMAN
    Recommended name:
    Zinc finger protein 654
    Protein Accession:
    Q8IZM8
    Secondary Accessions:
    • Q9H791
    • Q9NV14

    Protein attributes for ZNF654 Gene

    Size:
    581 amino acids
    Molecular mass:
    65854 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAN40504.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA91946.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB15007.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF654 Gene

Proteomics data for ZNF654 Gene at MOPED

Post-translational modifications for ZNF654 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF654 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF654 Gene

Domains for ZNF654 Gene

Protein Domains for ZNF654 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF654 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IZM8

UniProtKB/Swiss-Prot:

ZN654_HUMAN :
  • Q8IZM8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF654: view

No data available for Gene Families for ZNF654 Gene

Function for ZNF654 Gene

Molecular function for ZNF654 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF654 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF654: view

Animal Model Products

CRISPR Products

miRNA for ZNF654 Gene

miRTarBase miRNAs that target ZNF654

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF654

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF654 Gene

Localization for ZNF654 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF654 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF654 Gene COMPARTMENTS Subcellular localization image for ZNF654 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF654 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF654: view

Pathways for ZNF654 Gene

SuperPathways for ZNF654 Gene

No Data Available

Interacting Proteins for ZNF654 Gene

Gene Ontology (GO) - Biological Process for ZNF654 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF654: view

No data available for Pathways by source for ZNF654 Gene

Transcripts for ZNF654 Gene

mRNA/cDNA for ZNF654 Gene

(65) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF654 Gene

Zinc finger protein 654:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF654

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF654 Gene

No ASD Table

Relevant External Links for ZNF654 Gene

GeneLoc Exon Structure for
ZNF654
ECgene alternative splicing isoforms for
ZNF654

Expression for ZNF654 Gene

mRNA expression in normal human tissues for ZNF654 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ZNF654 Gene

This gene is overexpressed in Prostate (45.1) and CD8 Tcells (23.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF654 Gene

SOURCE GeneReport for Unigene cluster for ZNF654 Gene Hs.591650

genes like me logo Genes that share expressions with ZNF654: view

Expression partners for ZNF654 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF654 Gene

Orthologs for ZNF654 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF654 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF654 35
  • 92.47 (n)
  • 90.86 (a)
dog
(Canis familiaris)
Mammalia ZNF654 35
  • 93.57 (n)
  • 92.6 (a)
mouse
(Mus musculus)
Mammalia Zfp654 35
  • 87.84 (n)
  • 85.96 (a)
Zfp654 16
Zfp654 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp654 35
  • 87.89 (n)
  • 84.56 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 26 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF654 36
  • 58 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF654 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF654 35
  • 68.44 (n)
  • 58.08 (a)
-- 36
  • 24 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 21 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia znf654 35
  • 56.02 (n)
  • 46.5 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100536880 35
  • 46.03 (n)
  • 35.24 (a)
znf654 36
  • 4 (a)
OneToMany
Species with no ortholog for ZNF654:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF654 Gene

ENSEMBL:
Gene Tree for ZNF654 (if available)
TreeFam:
Gene Tree for ZNF654 (if available)

Paralogs for ZNF654 Gene

Paralogs for ZNF654 Gene

Selected SIMAP similar genes for ZNF654 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF654 Gene

genes like me logo Genes that share paralogs with ZNF654: view

Variants for ZNF654 Gene

Relevant External Links for ZNF654 Gene

HapMap Linkage Disequilibrium report
ZNF654

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for ZNF654 Gene

Disorders for ZNF654 Gene

No disorders were found for ZNF654 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF654 Gene

Publications for ZNF654 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for ZNF654 Gene

Sources for ZNF654 Gene

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