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Aliases for ZNF652 Gene

Aliases for ZNF652 Gene

  • Zinc Finger Protein 652 2 3
  • KIAA0924 4 6

External Ids for ZNF652 Gene

Summaries for ZNF652 Gene

GeneCards Summary for ZNF652 Gene

ZNF652 (Zinc Finger Protein 652) is a Protein Coding gene. An important paralog of this gene is ZBTB47.

UniProtKB/Swiss-Prot for ZNF652 Gene

  • Functions as a transcriptional repressor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF652 Gene

Genomics for ZNF652 Gene

Genomic Location for ZNF652 Gene

Start:
49,289,206 bp from pter
End:
49,362,473 bp from pter
Size:
73,268 bases
Orientation:
Minus strand

Genomic View for ZNF652 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF652 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF652 Gene

Regulatory Elements for ZNF652 Gene

Proteins for ZNF652 Gene

  • Protein details for ZNF652 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2D9-ZN652_HUMAN
    Recommended name:
    Zinc finger protein 652
    Protein Accession:
    Q9Y2D9
    Secondary Accessions:
    • A4QPD9
    • Q5H9Q0

    Protein attributes for ZNF652 Gene

    Size:
    606 amino acids
    Molecular mass:
    69744 Da
    Quaternary structure:
    • Interacts with CBFA2T3.
    SequenceCaution:
    • Sequence=BAA76768.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF652 Gene

Proteomics data for ZNF652 Gene at MOPED

Post-translational modifications for ZNF652 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF652 Gene

No data available for DME Specific Peptides for ZNF652 Gene

Domains for ZNF652 Gene

Gene Families for ZNF652 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF652 Gene

UniProtKB/Swiss-Prot:

ZN652_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9Y2D9
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q9Y2D9
genes like me logo Genes that share domains with ZNF652: view

Function for ZNF652 Gene

Molecular function for ZNF652 Gene

UniProtKB/Swiss-Prot Function: Functions as a transcriptional repressor.

Gene Ontology (GO) - Molecular Function for ZNF652 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16966434
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF652: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF652 Gene

Localization for ZNF652 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF652 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF652 Gene COMPARTMENTS Subcellular localization image for ZNF652 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF652 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF652: view

Pathways for ZNF652 Gene

SuperPathways for ZNF652 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF652 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF652: view

No data available for Pathways by source for ZNF652 Gene

Transcripts for ZNF652 Gene

Unigene Clusters for ZNF652 Gene

Zinc finger protein 652:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF652 Gene

No ASD Table

Relevant External Links for ZNF652 Gene

GeneLoc Exon Structure for
ZNF652
ECgene alternative splicing isoforms for
ZNF652

Expression for ZNF652 Gene

mRNA expression in normal human tissues for ZNF652 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF652 Gene

SOURCE GeneReport for Unigene cluster for ZNF652 Gene Hs.463375

mRNA Expression by UniProt/SwissProt for ZNF652 Gene

Q9Y2D9-ZN652_HUMAN
Tissue specificity: Widely expressed with higher expression in breast, prostate, vulva and pancreas.
genes like me logo Genes that share expressions with ZNF652: view

Orthologs for ZNF652 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF652 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF652 36
  • 99.78 (n)
  • 99.83 (a)
ZNF652 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF652 36
  • 94.44 (n)
  • 96.7 (a)
ZNF652 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF652 36
  • 94.22 (n)
  • 96.86 (a)
ZNF652 37
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp652 36
  • 88.21 (n)
  • 91.07 (a)
Zfp652 16
Zfp652 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF652 37
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF652 37
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp652 36
  • 89.04 (n)
  • 91.74 (a)
chicken
(Gallus gallus)
Aves ZNF652 36
  • 85.75 (n)
  • 92.57 (a)
ZNF652 37
  • 91 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF652 37
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.14592 36
zebrafish
(Danio rerio)
Actinopterygii znf652 36
  • 62.76 (n)
  • 63.2 (a)
znf652 37
  • 59 (a)
OneToOne
Species with no ortholog for ZNF652:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF652 Gene

ENSEMBL:
Gene Tree for ZNF652 (if available)
TreeFam:
Gene Tree for ZNF652 (if available)

Paralogs for ZNF652 Gene

Paralogs for ZNF652 Gene

Pseudogenes.org Pseudogenes for ZNF652 Gene

genes like me logo Genes that share paralogs with ZNF652: view

Variants for ZNF652 Gene

Sequence variations from dbSNP and Humsavar for ZNF652 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs747039 -- 49,329,551(-) CCATA(C/T)AAAAT intron-variant
rs917051 -- 49,306,583(-) GCGAC(C/G)AGGTG intron-variant
rs1060868 -- 49,352,497(-) CTGTT(A/T)ATATT intron-variant
rs1137053 -- 49,313,969(+) actcc(A/G/T)tctca intron-variant
rs1343795 -- 49,334,880(-) aacta(G/T)gtagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF652 Gene

Variant ID Type Subtype PubMed ID
esv271977 CNV Insertion 20981092
nsv526307 CNV Gain 19592680
nsv2075 CNV Loss 18451855

Relevant External Links for ZNF652 Gene

HapMap Linkage Disequilibrium report
ZNF652

Disorders for ZNF652 Gene

Relevant External Links for ZNF652

Genetic Association Database (GAD)
ZNF652
Human Genome Epidemiology (HuGE) Navigator
ZNF652
genes like me logo Genes that share disorders with ZNF652: view

No data available for UniProtKB/Swiss-Prot for ZNF652 Gene

Publications for ZNF652 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4
  2. ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription. (PMID: 16966434) Kumar R. … Callen D.F. (Mol. Cancer Res. 2006) 3 4
  3. Genome-wide association study identifies eight loci associated with blood pressure. (PMID: 19430483) Newton-Cheh C. … Munroe P.B. (Nat. Genet. 2009) 3 49
  4. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (PMID: 21909110) Wain L.V. … van Duijn C.M. (Nat. Genet. 2011) 3 49
  5. Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population. (PMID: 20414254) Hong K.W. … Oh B. (J. Hum. Genet. 2010) 3 49

Products for ZNF652 Gene

Sources for ZNF652 Gene

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