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Aliases for ZNF648 Gene

Aliases for ZNF648 Gene

  • Zinc Finger Protein 648 2 3

External Ids for ZNF648 Gene

Previous GeneCards Identifiers for ZNF648 Gene

  • GC01M178755
  • GC01M180290
  • GC01M153255

Summaries for ZNF648 Gene

GeneCards Summary for ZNF648 Gene

ZNF648 (Zinc Finger Protein 648) is a Protein Coding gene. An important paralog of this gene is ZNF70.

UniProtKB/Swiss-Prot for ZNF648 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF648 Gene

Genomics for ZNF648 Gene

Regulatory Elements for ZNF648 Gene

Genomic Location for ZNF648 Gene

Start:
182,054,570 bp from pter
End:
182,061,712 bp from pter
Size:
7,143 bases
Orientation:
Minus strand

Genomic View for ZNF648 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF648 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF648 Gene

Proteins for ZNF648 Gene

  • Protein details for ZNF648 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T619-ZN648_HUMAN
    Recommended name:
    Zinc finger protein 648
    Protein Accession:
    Q5T619
    Secondary Accessions:
    • B2RP16

    Protein attributes for ZNF648 Gene

    Size:
    568 amino acids
    Molecular mass:
    62341 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF648 Gene

Proteomics data for ZNF648 Gene at MOPED

Post-translational modifications for ZNF648 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF648 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF648 Gene

Domains for ZNF648 Gene

Gene Families for ZNF648 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF648 Gene

Suggested Antigen Peptide Sequences for ZNF648 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T619

UniProtKB/Swiss-Prot:

ZN648_HUMAN :
  • Q5T619
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF648: view

Function for ZNF648 Gene

Molecular function for ZNF648 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF648 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF648: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF648 Gene

Localization for ZNF648 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF648 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF648 Gene COMPARTMENTS Subcellular localization image for ZNF648 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF648 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF648: view

Pathways for ZNF648 Gene

SuperPathways for ZNF648 Gene

No Data Available

Interacting Proteins for ZNF648 Gene

Gene Ontology (GO) - Biological Process for ZNF648 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF648: view

No data available for Pathways by source for ZNF648 Gene

Transcripts for ZNF648 Gene

mRNA/cDNA for ZNF648 Gene

(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF648 Gene

Zinc finger protein 648:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF648

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF648
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF648 Gene

No ASD Table

Relevant External Links for ZNF648 Gene

GeneLoc Exon Structure for
ZNF648
ECgene alternative splicing isoforms for
ZNF648

Expression for ZNF648 Gene

mRNA expression in normal human tissues for ZNF648 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF648 Gene

This gene is overexpressed in Testis (10.7), Liver (4.6), Pituitary (4.1), and Ovary (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF648 Gene

SOURCE GeneReport for Unigene cluster for ZNF648 Gene Hs.684328

genes like me logo Genes that share expressions with ZNF648: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF648 Gene

Orthologs for ZNF648 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF648 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF648 35
  • 99.3 (n)
  • 98.42 (a)
ZNF648 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF648 35
  • 83 (n)
  • 75.76 (a)
ZNF648 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF648 35
  • 84.07 (n)
  • 78.58 (a)
ZNF648 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp648 35
  • 77.76 (n)
  • 71.32 (a)
Zfp648 16
Zfp648 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp648 35
  • 76.19 (n)
  • 68.42 (a)
zebrafish
(Danio rerio)
Actinopterygii znf648 36
  • 38 (a)
OneToOne
Species with no ortholog for ZNF648:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF648 Gene

ENSEMBL:
Gene Tree for ZNF648 (if available)
TreeFam:
Gene Tree for ZNF648 (if available)

Paralogs for ZNF648 Gene

Paralogs for ZNF648 Gene

Selected SIMAP similar genes for ZNF648 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF648: view

Variants for ZNF648 Gene

Sequence variations from dbSNP and Humsavar for ZNF648 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs2332967 -- 182,059,081(+) CTCCC(A/G)AAGTG intron-variant
rs6424835 -- 182,062,428(+) TGTGA(C/T)GTCAC upstream-variant-2KB
rs6656200 -- 182,058,716(+) GAAGG(C/G)TACCC intron-variant
rs6660589 -- 182,054,377(+) ACACT(A/G)CAGAC downstream-variant-500B
rs6673142 -- 182,063,465(+) ttgag(C/G)tcttt upstream-variant-2KB

Relevant External Links for ZNF648 Gene

HapMap Linkage Disequilibrium report
ZNF648

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF648 Gene

Disorders for ZNF648 Gene

Relevant External Links for ZNF648

Genetic Association Database (GAD)
ZNF648
genes like me logo Genes that share disorders with ZNF648: view

No data available for UniProtKB/Swiss-Prot for ZNF648 Gene

Publications for ZNF648 Gene

  1. Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich T.M. … Kathiresan S. (Nature 2010) 3 48
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. (PMID: 23982368) Qi L. … Doria A. (JAMA 2013) 3

Products for ZNF648 Gene

Sources for ZNF648 Gene

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