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Aliases for ZNF629 Gene

Aliases for ZNF629 Gene

  • Zinc Finger Protein 629 2 3 5
  • Zinc Finger Protein 65 2 3 4
  • ZNF65 3 4
  • DNA-Binding Protein 3
  • KIAA0326 4
  • ZNF 3

External Ids for ZNF629 Gene

Previous HGNC Symbols for ZNF629 Gene

  • ZNF65

Previous GeneCards Identifiers for ZNF629 Gene

  • GC16M030830
  • GC16M030700
  • GC16M030697
  • GC16M028352

Summaries for ZNF629 Gene

GeneCards Summary for ZNF629 Gene

ZNF629 (Zinc Finger Protein 629) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN2.

UniProtKB/Swiss-Prot for ZNF629 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF629 Gene

Genomics for ZNF629 Gene

Regulatory Elements for ZNF629 Gene

Enhancers for ZNF629 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G030566 2.1 FANTOM5 Ensembl ENCODE dbSUPER 21 +217.4 217403 6.0 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 SP3 ENSG00000260267 ZNF747 NPIPB13 ENSG00000260304 SMG1P2 BCL7C ZNF764 ZNF785 CDIPT PRR14
GH16G030872 1.6 FANTOM5 ENCODE 22.7 -87.6 -87608 5.3 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZNF720 BCL7C CCDC189 ZNF629 HSD3B7 ENSG00000260267 ZNF785 ZNF771 RNF40 ZNF747
GH16G030555 1.5 ENCODE dbSUPER 21 +229.2 229206 4.2 CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 ENSG00000260267 ZNF764 SMG1P2 NPIPB13 ENSG00000260304 BCL7C PRR14 CDIPT ZNF785 ZNF689
GH16G030052 1.5 ENCODE dbSUPER 20.9 +733.1 733073 3.1 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF548 ZNF747 SMG1P2 ZNF764 ENSG00000198106 BCL7C NPIPB13 PRR14 ZNF785 CDIPT YPEL3
GH16G030334 1.1 ENCODE 20.9 +451.9 451916 2.6 PKNOX1 FOXA2 ZFP64 ARID4B SIN3A DMAP1 YY1 KLF13 ZNF263 SP3 ZNF747 BCL7C NPIPB13 ENSG00000260304 SMG1P2 ZNF785 ZNF629 ZNF764 ZNF689 SMG1P5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF629 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF629 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085249 277 1201 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 ZNF2 ZBTB7B YY1 SLC30A9 ZNF143

Genomic Location for ZNF629 Gene

Chromosome:
16
Start:
30,778,449 bp from pter
End:
30,787,277 bp from pter
Size:
8,829 bases
Orientation:
Minus strand

Genomic View for ZNF629 Gene

Genes around ZNF629 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF629 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF629 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF629 Gene

Proteins for ZNF629 Gene

  • Protein details for ZNF629 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UEG4-ZN629_HUMAN
    Recommended name:
    Zinc finger protein 629
    Protein Accession:
    Q9UEG4
    Secondary Accessions:
    • Q15938

    Protein attributes for ZNF629 Gene

    Size:
    869 amino acids
    Molecular mass:
    96620 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA20784.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF629 Gene

Post-translational modifications for ZNF629 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF629 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF629 Gene

Domains & Families for ZNF629 Gene

Gene Families for ZNF629 Gene

Protein Domains for ZNF629 Gene

Suggested Antigen Peptide Sequences for ZNF629 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UEG4

UniProtKB/Swiss-Prot:

ZN629_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF629: view

Function for ZNF629 Gene

Molecular function for ZNF629 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF629: view
genes like me logo Genes that share phenotypes with ZNF629: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF629 Gene

Localization for ZNF629 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF629 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF629 gene
Compartment Confidence
nucleus 5
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF629: view

Pathways & Interactions for ZNF629 Gene

SuperPathways for ZNF629 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
genes like me logo Genes that share ontologies with ZNF629: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF629 Gene

Drugs & Compounds for ZNF629 Gene

No Compound Related Data Available

Transcripts for ZNF629 Gene

mRNA/cDNA for ZNF629 Gene

(3) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF629 Gene

Zinc finger protein 629:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF629 Gene

No ASD Table

Relevant External Links for ZNF629 Gene

GeneLoc Exon Structure for
ZNF629
ECgene alternative splicing isoforms for
ZNF629

Expression for ZNF629 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF629 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF629 Gene

This gene is overexpressed in Platelet (25.7), Fetal Brain (22.6), and Retina (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF629 Gene



Protein tissue co-expression partners for ZNF629 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF629 Gene:

ZNF629

SOURCE GeneReport for Unigene cluster for ZNF629 Gene:

Hs.301094

Evidence on tissue expression from TISSUES for ZNF629 Gene

  • Nervous system(4.4)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with ZNF629: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF629 Gene

Orthologs for ZNF629 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF629 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF629 34 35
  • 99.58 (n)
dog
(Canis familiaris)
Mammalia ZNF629 34 35
  • 90.28 (n)
cow
(Bos Taurus)
Mammalia ZNF629 34 35
  • 90.25 (n)
mouse
(Mus musculus)
Mammalia Zfp629 34 16 35
  • 86.08 (n)
rat
(Rattus norvegicus)
Mammalia Zfp629 34
  • 85.99 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF629 35
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF629 35
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 35
  • 40 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 49 (a)
OneToMany
-- 35
  • 48 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 40 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 38 (a)
OneToMany
-- 35
  • 38 (a)
OneToMany
-- 35
  • 37 (a)
OneToMany
-- 35
  • 34 (a)
OneToMany
-- 35
  • 33 (a)
OneToMany
-- 35
  • 27 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii si:zfos-44a5.2 35
  • 45 (a)
ManyToMany
BX640537.2 35
  • 41 (a)
ManyToMany
AL954741.1 35
  • 40 (a)
ManyToMany
CABZ01006831.1 35
  • 39 (a)
ManyToMany
CABZ01006835.1 35
  • 38 (a)
ManyToMany
CU672268.1 35
  • 38 (a)
ManyToMany
zgc:174712 35
  • 37 (a)
ManyToMany
CABZ01075191.1 35
  • 36 (a)
ManyToMany
si:dkey-20i20.5 35
  • 36 (a)
ManyToMany
si:ch211-235i11.2 35
  • 34 (a)
ManyToMany
CABZ01048402.1 35
  • 33 (a)
ManyToMany
BX000701.1 35
  • 32 (a)
ManyToMany
zgc:113389 35
  • 31 (a)
ManyToMany
FP326649.1 35
  • 30 (a)
ManyToMany
Species where no ortholog for ZNF629 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF629 Gene

ENSEMBL:
Gene Tree for ZNF629 (if available)
TreeFam:
Gene Tree for ZNF629 (if available)

Paralogs for ZNF629 Gene

Paralogs for ZNF629 Gene

(476) SIMAP similar genes for ZNF629 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF629: view

Variants for ZNF629 Gene

Sequence variations from dbSNP and Humsavar for ZNF629 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000152871 -- 30,778,930(+) CTTCA(A/T)CTGAG intron-variant, utr-variant-3-prime
rs1000387459 -- 30,786,774(+) GCAGC(A/G)CTGGT intron-variant
rs1000611485 -- 30,783,891(+) TCTCC(A/G)CCCCC intron-variant, reference, missense
rs1001054900 -- 30,785,957(+) CACAG(C/G)AACAA intron-variant
rs1001081345 -- 30,782,609(+) CCGCA(C/T)ACGAG intron-variant, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF629 Gene

Variant ID Type Subtype PubMed ID
nsv469724 CNV loss 16826518
nsv833188 CNV loss 17160897
nsv9438 CNV gain 18304495

Variation tolerance for ZNF629 Gene

Residual Variation Intolerance Score: 23.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.65; 45.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF629 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF629

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF629 Gene

Disorders for ZNF629 Gene

Relevant External Links for ZNF629

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF629

No disorders were found for ZNF629 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF629 Gene

Publications for ZNF629 Gene

  1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 2 3 4 64
  2. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 3 4 64
  3. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P.L. … Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 1991) 3 4 64
  4. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3 64
  5. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 64

Products for ZNF629 Gene

Sources for ZNF629 Gene

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