ZNF629 Gene
protein-coding GIFtS: 40
GCID: GC16M030789
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zinc finger protein 629(Previous name: zinc finger protein 65 )
(Previous symbol: ZNF65)
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Aliases
for ZNF629 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6291 2 | | Zinc Finger Protein 651 2 3 | | ZNF651 2 3 | | KIAA03261 3 | | ZNF2 | | DNA-Binding Protein2 |
Export aliases for ZNF629 gene to outside databasesPrevious GC identifers: GC16M030830 GC16M030700 GC16M030697 GC16M028352 |
Summaries
for ZNF629 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN629_HUMAN, Q9UEG4Function: May be involved in transcriptional regulation
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Genomic Views
for ZNF629 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF629 gene promoter:
Bach2 Olf-1 LCR-F1 NF-E2 p45 HEN1 RORalpha1 MRF-2 NF-E2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF629
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF629 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2ZNF629 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M030789: view genomic region
(about GC identifiers)
Start:
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30,789,770 bp from pter |
End:
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30,798,523 bp from pter |
Size:
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8,754 bases |
Orientation:
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minus strand |
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Proteins
for ZNF629 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN629_HUMAN, Q9UEG4 (See
protein sequence)Recommended Name: Zinc finger protein 629 Size: 869 amino acids; 96620 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA20784.1; Type=Erroneous initiation;
Secondary accessions: Q15938Explore the universe of human proteins at neXtProt for ZNF629: NX_Q9UEG4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UEG4
ZNF629 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073886.1
ENSEMBL proteins: ENSP00000262525
Human Recombinant Protein Products for ZNF629:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- |
ZNF629 for ontologies About GeneDecksing
ZNF629 Antibody Products:
Assay Products for ZNF629: |
Protein
Domains /
Families
for ZNF629 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF629 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UEG4ProtoNet protein and cluster: Q9UEG4 UniProtKB/Swiss-Prot: ZN629_HUMAN, Q9UEG4Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 19 C2H2-type zinc fingers |
Function
for ZNF629 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN629_HUMAN, Q9UEG4Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF629 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF629 (NM_001080417) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF629 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF629 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF629 |
|
Pathways & Interactions
for ZNF629 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF629
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF629 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF629 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF629
Search CenterWatch for drugs/clinical trials and news about ZNF629 / ZN629
|
Transcripts
for ZNF629 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF629 gene: NM_001080417.1 Unigene Cluster for ZNF629: Zinc finger protein 629 Hs.301094 [show with all ESTs]Unigene Representative Sequence: NM_0010804171 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000262525(uc002dzs.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF629 (NM_001080417) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF629 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF629 |
Additional cDNA sequence: AB002324.1 AK026115.1 BC015676.2 BC047041.1 BC063520.1 BC080594.1 2 DOTS entries: DT.313763 DT.91926972 24/111 AceView cDNA sequences (see all 111): F03007 BU608861 BX643362 C02488 BQ933244 CA429849 BQ928892 BC063520 BM819155 BQ937134 BE883524 BC015676 BU542770 BG392937 BQ428180 CA426124 BU542127 BM794110 Z45297 AL044847 AK026115 BM564352 Z41004 BG823125
GeneLoc Exon Structure
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Expression
for ZNF629 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF629 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGCTTAGTT
About this image
See ZNF629 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF629
SOURCE GeneReport for Unigene cluster: Hs.301094
SABiosciences Custom PCR Arrays for ZNF629
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF629
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF629 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF629 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF629 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF629 |
Orthologs
for ZNF629 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF629 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for ZNF629 (if available)
TreeFam Gene Tree for ZNF629 (if available) |
Paralogs
for ZNF629 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF629 gene
- ZSCAN22 ZNF4362 ZNF7742 ZNF6912 ZNF5722 ZNF6972 ZNF2052
18/472 SIMAP similar genes for ZNF629 using alignment to 1 protein entry: ZN629_HUMAN(see all similar genes):ZNF78L1 DKFZp666C237 ZFS-4 ZNF24 ZNF818P HZF36
ZNF250 kr-znf3 ZNF ZNF852 ZNF286A ZNF696
ZNF774 zf30 ZNF146 ZNF180 ZNF286B ZNF300
ZNF629 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF629 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF629 (30789770 - 30798523 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF629
2 CNVs: 30780 2209 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF629 |
|
Disorders
/ Diseases
for ZNF629 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF629 for disorders About GeneDecksing
1  disease for ZNF629: About MalaCardsenamel erosion
Export disorders for ZNF629 gene to outside databases
|
Publications
for ZNF629 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF629 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF629) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PubMed id 1505991)1, 2 Lichter P....Ward D.C. (1992)
- Characterization and mapping of human genes encoding zinc finger proteins. (PubMed id 1946370)1, 2 Bray P.L.... Dawid I.B. (1991)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF629 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZNF629 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF629 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF629 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF629 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF629 gene:
Search GeneIP for patents involving ZNF629
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF629 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF629 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF629 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF629 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF629 | | OriGene 3'-UTR Clone for ZNF629 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF629 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | ZNF629 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF629 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF629 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF629 |
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