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Aliases for ZNF629 Gene

Aliases for ZNF629 Gene

  • Zinc Finger Protein 629 2 3
  • Zinc Finger Protein 65 2 3 4
  • ZNF65 3 4
  • DNA-Binding Protein 3
  • KIAA0326 4
  • ZNF 3

External Ids for ZNF629 Gene

Previous HGNC Symbols for ZNF629 Gene

  • ZNF65

Previous GeneCards Identifiers for ZNF629 Gene

  • GC16M030830
  • GC16M030700
  • GC16M030697
  • GC16M028352

Summaries for ZNF629 Gene

GeneCards Summary for ZNF629 Gene

ZNF629 (Zinc Finger Protein 629) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF629 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF629 Gene

Genomics for ZNF629 Gene

Regulatory Elements for ZNF629 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF629 Gene

Chromosome:
16
Start:
30,778,449 bp from pter
End:
30,787,277 bp from pter
Size:
8,829 bases
Orientation:
Minus strand

Genomic View for ZNF629 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF629 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF629 Gene

Proteins for ZNF629 Gene

  • Protein details for ZNF629 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UEG4-ZN629_HUMAN
    Recommended name:
    Zinc finger protein 629
    Protein Accession:
    Q9UEG4
    Secondary Accessions:
    • Q15938

    Protein attributes for ZNF629 Gene

    Size:
    869 amino acids
    Molecular mass:
    96620 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA20784.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF629 Gene

Proteomics data for ZNF629 Gene at MOPED

Post-translational modifications for ZNF629 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF629 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF629 Gene

Domains & Families for ZNF629 Gene

Gene Families for ZNF629 Gene

Protein Domains for ZNF629 Gene

Suggested Antigen Peptide Sequences for ZNF629 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UEG4

UniProtKB/Swiss-Prot:

ZN629_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF629: view

Function for ZNF629 Gene

Molecular function for ZNF629 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF629: view

Phenotypes for ZNF629 Gene

genes like me logo Genes that share phenotypes with ZNF629: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF629

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF629 Gene

Localization for ZNF629 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF629 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF629 Gene COMPARTMENTS Subcellular localization image for ZNF629 gene
Compartment Confidence
nucleus 3
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF629: view

Pathways & Interactions for ZNF629 Gene

SuperPathways for ZNF629 Gene

No Data Available

Interacting Proteins for ZNF629 Gene

Gene Ontology (GO) - Biological Process for ZNF629 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF629: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF629 Gene

Drugs & Compounds for ZNF629 Gene

No Compound Related Data Available

Transcripts for ZNF629 Gene

mRNA/cDNA for ZNF629 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(111) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF629 Gene

Zinc finger protein 629:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF629

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF629 Gene

No ASD Table

Relevant External Links for ZNF629 Gene

GeneLoc Exon Structure for
ZNF629
ECgene alternative splicing isoforms for
ZNF629

Expression for ZNF629 Gene

mRNA expression in normal human tissues for ZNF629 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF629 Gene

This gene is overexpressed in Platelet (25.7), Fetal Brain (22.6), and Retina (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF629 Gene



SOURCE GeneReport for Unigene cluster for ZNF629 Gene Hs.301094

genes like me logo Genes that share expression patterns with ZNF629: view

Protein tissue co-expression partners for ZNF629 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF629 Gene

Orthologs for ZNF629 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF629 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF629 35
  • 90.25 (n)
  • 91.71 (a)
ZNF629 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF629 35
  • 90.28 (n)
  • 93.09 (a)
ZNF629 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp629 35
  • 86.08 (n)
  • 89.16 (a)
Zfp629 16
Zfp629 36
  • 89 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF629 35
  • 99.58 (n)
  • 98.96 (a)
ZNF629 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp629 35
  • 85.99 (n)
  • 89.15 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF629 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF629 36
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 40 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
OneToMany
-- 36
  • 40 (a)
OneToMany
-- 36
  • 38 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 37 (a)
OneToMany
-- 36
  • 34 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 38 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii AL954741.1 36
  • 40 (a)
ManyToMany
BX000701.1 36
  • 32 (a)
ManyToMany
BX640537.2 36
  • 41 (a)
ManyToMany
CABZ01006831.1 36
  • 39 (a)
ManyToMany
CABZ01006835.1 36
  • 38 (a)
ManyToMany
CABZ01048402.1 36
  • 33 (a)
ManyToMany
CABZ01075191.1 36
  • 36 (a)
ManyToMany
CU672268.1 36
  • 38 (a)
ManyToMany
FP326649.1 36
  • 30 (a)
ManyToMany
si:ch211-235i11.2 36
  • 34 (a)
ManyToMany
si:dkey-20i20.5 36
  • 36 (a)
ManyToMany
si:zfos-44a5.2 36
  • 45 (a)
ManyToMany
zgc:113389 36
  • 31 (a)
ManyToMany
zgc:174712 36
  • 37 (a)
ManyToMany
Species with no ortholog for ZNF629:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF629 Gene

ENSEMBL:
Gene Tree for ZNF629 (if available)
TreeFam:
Gene Tree for ZNF629 (if available)

Paralogs for ZNF629 Gene

(476) SIMAP similar genes for ZNF629 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF629: view

Variants for ZNF629 Gene

Sequence variations from dbSNP and Humsavar for ZNF629 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
VAR_052883 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF629 Gene

Variant ID Type Subtype PubMed ID
nsv469724 CNV Loss 16826518
nsv833188 CNV Loss 17160897
nsv905728 CNV Loss 21882294
nsv905729 CNV Loss 21882294
nsv9438 CNV Gain 18304495
nsv905732 CNV Loss 21882294
nsv905733 CNV Loss 21882294

Variation tolerance for ZNF629 Gene

Residual Variation Intolerance Score: 23.18% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.65; 45.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF629 Gene

HapMap Linkage Disequilibrium report
ZNF629

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF629 Gene

Disorders for ZNF629 Gene

Relevant External Links for ZNF629

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF629
genes like me logo Genes that share disorders with ZNF629: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF629 Gene

Publications for ZNF629 Gene

  1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T. … Ohara O. (DNA Res. 1997) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 67
  4. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  5. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. (PMID: 23449627) Cousminer D.L. … WidAcn E. (Hum. Mol. Genet. 2013) 67

Products for ZNF629 Gene

Sources for ZNF629 Gene

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