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Aliases for ZNF626 Gene

Aliases for ZNF626 Gene

  • Zinc Finger Protein 626 2 3
  • CTC-513N18.7 3

External Ids for ZNF626 Gene

Summaries for ZNF626 Gene

GeneCards Summary for ZNF626 Gene

ZNF626 (Zinc Finger Protein 626) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF626 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF626 Gene

Genomics for ZNF626 Gene

Genomic Location for ZNF626 Gene

Start:
20,544,571 bp from pter
End:
20,863,281 bp from pter
Size:
318,711 bases
Orientation:
Minus strand

Genomic View for ZNF626 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF626 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF626 Gene

Regulatory Elements for ZNF626 Gene

Proteins for ZNF626 Gene

  • Protein details for ZNF626 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68DY1-ZN626_HUMAN
    Recommended name:
    Zinc finger protein 626
    Protein Accession:
    Q68DY1
    Secondary Accessions:
    • Q8N8T4
    • Q96QM1

    Protein attributes for ZNF626 Gene

    Size:
    528 amino acids
    Molecular mass:
    60893 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04729.1; Type=Miscellaneous discrepancy; Note=Intron-exon boundaries of the last intron are not canonical, they have a CT-AG boundary.; Evidence={ECO:0000305}; Sequence=CAH18089.1; Type=Miscellaneous discrepancy; Note=Intron-exon boundaries of the last intron are not canonical, they have a CT-AG boundary.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF626 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF626 Gene

Proteomics data for ZNF626 Gene at MOPED

Post-translational modifications for ZNF626 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys292 and Lys398

Other Protein References for ZNF626 Gene

No data available for DME Specific Peptides for ZNF626 Gene

Domains for ZNF626 Gene

Gene Families for ZNF626 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF626 Gene

UniProtKB/Swiss-Prot:

ZN626_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q68DY1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q68DY1
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q68DY1
genes like me logo Genes that share domains with ZNF626: view

Function for ZNF626 Gene

Molecular function for ZNF626 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF626 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF626: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF626 Gene

Localization for ZNF626 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF626 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF626 Gene COMPARTMENTS Subcellular localization image for ZNF626 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF626 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF626: view

Pathways for ZNF626 Gene

SuperPathways for ZNF626 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF626: view

Pathways by source for ZNF626 Gene

2 Reactome pathways for ZNF626 Gene

Interacting Proteins for ZNF626 Gene

Gene Ontology (GO) - Biological Process for ZNF626 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF626: view

Transcripts for ZNF626 Gene

mRNA/cDNA for ZNF626 Gene

(2) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF626 Gene

Zinc finger protein 626:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF626 Gene

No ASD Table

Relevant External Links for ZNF626 Gene

GeneLoc Exon Structure for
ZNF626
ECgene alternative splicing isoforms for
ZNF626

Expression for ZNF626 Gene

mRNA expression in normal human tissues for ZNF626 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF626 Gene

SOURCE GeneReport for Unigene cluster for ZNF626 Gene Hs.657001

genes like me logo Genes that share expressions with ZNF626: view

Orthologs for ZNF626 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF626 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 63 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 37
  • 51 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 36 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp386 37
  • 35 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 37 (a)
ManyToMany
-- 37
  • 48 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 50 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 40 (a)
ManyToMany
-- 37
  • 38 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF626:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF626 Gene

ENSEMBL:
Gene Tree for ZNF626 (if available)
TreeFam:
Gene Tree for ZNF626 (if available)

Paralogs for ZNF626 Gene

Selected SIMAP similar genes for ZNF626 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF626 Gene

genes like me logo Genes that share paralogs with ZNF626: view

Variants for ZNF626 Gene

Sequence variations from dbSNP and Humsavar for ZNF626 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs274797 -- 20,662,960(+) tctgt(A/G)caggg upstream-variant-2KB
rs274798 -- 20,661,811(+) TGGGA(A/G)AATTC upstream-variant-2KB
rs274799 -- 20,661,046(+) ccCCA(C/T)ACATT intron-variant
rs274800 -- 20,660,932(+) AAGTT(C/G)AGTCA intron-variant
rs274801 -- 20,659,959(+) aaaaa(A/C)taaca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF626 Gene

Variant ID Type Subtype PubMed ID
dgv550e201 CNV Deletion 23290073
dgv3794n71 CNV Loss 21882294
dgv3795n71 CNV Loss 21882294
dgv1063e1 CNV Complex 17122850
nsv458377 CNV Gain 19166990
dgv3804n71 CNV Loss 21882294
nsv911405 CNV Loss 21882294
esv2751781 CNV Gain 17911159
dgv3805n71 CNV Loss 21882294
nsv9676 CNV Gain 18304495
esv1003988 OTHER Inversion 20482838
dgv71e19 OTHER Inversion 19470904
esv2573650 OTHER Inversion 19546169
nsv436702 OTHER Inversion 17901297
esv2718318 CNV Deletion 23290073
esv1010023 CNV Deletion 20482838
esv1100051 CNV Deletion 17803354
nsv510470 CNV Loss 20534489
esv2751782 CNV Gain 17911159
nsv458512 CNV Gain 19166990
nsv911409 CNV Gain 21882294
dgv404n27 CNV Gain 19166990
nsv517256 CNV Gain 19592680

Relevant External Links for ZNF626 Gene

HapMap Linkage Disequilibrium report
ZNF626

Disorders for ZNF626 Gene

No disorders were found for ZNF626 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF626 Gene

Publications for ZNF626 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A protein-protein interaction network of transcription factors acting during liver cell proliferation. (PMID: 18255255) Gao J. … Yu Y. (Genomics 2008) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PMID: 23400010) Del-Aguila J.L. … Boerwinkle E. (Pharmacogenomics J. 2013) 3

Products for ZNF626 Gene

Sources for ZNF626 Gene

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