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Aliases for ZNF624 Gene

Aliases for ZNF624 Gene

  • Zinc Finger Protein 624 2 3 5
  • KIAA1349 4

External Ids for ZNF624 Gene

Previous GeneCards Identifiers for ZNF624 Gene

  • GC17M016724
  • GC17M016464
  • GC17M016390
  • GC17M016524
  • GC17M016620

Summaries for ZNF624 Gene

GeneCards Summary for ZNF624 Gene

ZNF624 (Zinc Finger Protein 624) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF729.

UniProtKB/Swiss-Prot for ZNF624 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF624 Gene

Genomics for ZNF624 Gene

Regulatory Elements for ZNF624 Gene

Enhancers for ZNF624 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF624 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF624 Gene

16,599,870 bp from pter
16,655,626 bp from pter
55,757 bases
Minus strand

Genomic View for ZNF624 Gene

Genes around ZNF624 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF624 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF624 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF624 Gene

Proteins for ZNF624 Gene

  • Protein details for ZNF624 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 624
    Protein Accession:
    Secondary Accessions:
    • Q3SY62
    • Q3SY63
    • Q6ZN27

    Protein attributes for ZNF624 Gene

    865 amino acids
    Molecular mass:
    99929 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA92587.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF624 Gene


neXtProt entry for ZNF624 Gene

Proteomics data for ZNF624 Gene at MOPED

Post-translational modifications for ZNF624 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF624 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF624 Gene

Domains & Families for ZNF624 Gene

Gene Families for ZNF624 Gene

Protein Domains for ZNF624 Gene

Suggested Antigen Peptide Sequences for ZNF624 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 21 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 21 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF624: view

Function for ZNF624 Gene

Molecular function for ZNF624 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF624 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF624: view
genes like me logo Genes that share phenotypes with ZNF624: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF624 Gene

Localization for ZNF624 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF624 Gene

Subcellular locations from

Jensen Localization Image for ZNF624 Gene COMPARTMENTS Subcellular localization image for ZNF624 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF624 Gene

Pathways & Interactions for ZNF624 Gene

SuperPathways for ZNF624 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF624: view

Pathways by source for ZNF624 Gene

2 Reactome pathways for ZNF624 Gene

Interacting Proteins for ZNF624 Gene

Gene Ontology (GO) - Biological Process for ZNF624 Gene


No data available for SIGNOR curated interactions for ZNF624 Gene

Drugs & Compounds for ZNF624 Gene

No Compound Related Data Available

Transcripts for ZNF624 Gene

mRNA/cDNA for ZNF624 Gene

Unigene Clusters for ZNF624 Gene

Zinc finger protein 624:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF624 Gene

No ASD Table

Relevant External Links for ZNF624 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF624 Gene

mRNA expression in normal human tissues for ZNF624 Gene

Protein differential expression in normal tissues from HIPED for ZNF624 Gene

This gene is overexpressed in Breast (64.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF624 Gene

SOURCE GeneReport for Unigene cluster for ZNF624 Gene Hs.128078

genes like me logo Genes that share expression patterns with ZNF624: view

Protein tissue co-expression partners for ZNF624 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF624 Gene

Orthologs for ZNF624 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF624 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF624 35
  • 90.66 (n)
  • 91.49 (a)
ZNF624 36
  • 91 (a)
(Mus musculus)
Mammalia Gm3055 35
  • 61.99 (n)
  • 53.46 (a)
Gm3055 16
Gm14124 36
  • 44 (a)
(Pan troglodytes)
Mammalia ZNF624 35
  • 99.65 (n)
  • 99.31 (a)
ZNF624 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC100909569 35
  • 61.22 (n)
  • 52.94 (a)
(Bos Taurus)
Mammalia ZNF624 36
  • 49 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
-- 36
  • 50 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 51 (a)
(Gallus gallus)
Aves LOC100858477 35
  • 54.11 (n)
  • 46.58 (a)
Species with no ortholog for ZNF624:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF624 Gene

Gene Tree for ZNF624 (if available)
Gene Tree for ZNF624 (if available)

Paralogs for ZNF624 Gene

(528) SIMAP similar genes for ZNF624 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF624: view

Variants for ZNF624 Gene

Sequence variations from dbSNP and Humsavar for ZNF624 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_035592 A colorectal cancer sample
rs8065506 - 16,624,481(+) GTAGC(A/C)TTCTT intron-variant, reference, missense
rs1005369 -- 16,606,603(+) CAAGG(G/T)TTAAT intron-variant
rs1005370 -- 16,607,154(+) GCAAG(C/G)CTCCT intron-variant
rs1008317 -- 16,599,851(+) CACAG(G/T)GTTTT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF624 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV Deletion 23290073
dgv928e1 CNV Complex 17122850

Variation tolerance for ZNF624 Gene

Residual Variation Intolerance Score: 24.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.74; 89.38% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF624 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF624 Gene

Disorders for ZNF624 Gene

Relevant External Links for ZNF624

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF624 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF624 Gene

Publications for ZNF624 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZNF624 Gene

Sources for ZNF624 Gene