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Aliases for ZNF624 Gene

Aliases for ZNF624 Gene

  • Zinc Finger Protein 624 2 3
  • KIAA1349 4

External Ids for ZNF624 Gene

Previous GeneCards Identifiers for ZNF624 Gene

  • GC17M016724
  • GC17M016464
  • GC17M016390
  • GC17M016524

Summaries for ZNF624 Gene

GeneCards Summary for ZNF624 Gene

ZNF624 (Zinc Finger Protein 624) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF624 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF624 Gene

Genomics for ZNF624 Gene

Regulatory Elements for ZNF624 Gene

Genomic Location for ZNF624 Gene

Start:
16,620,734 bp from pter
End:
16,653,856 bp from pter
Size:
33,123 bases
Orientation:
Minus strand

Genomic View for ZNF624 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF624 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF624 Gene

Proteins for ZNF624 Gene

  • Protein details for ZNF624 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P2J8-ZN624_HUMAN
    Recommended name:
    Zinc finger protein 624
    Protein Accession:
    Q9P2J8
    Secondary Accessions:
    • Q3SY62
    • Q3SY63
    • Q6ZN27

    Protein attributes for ZNF624 Gene

    Size:
    865 amino acids
    Molecular mass:
    99929 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA92587.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF624 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF624 Gene

Proteomics data for ZNF624 Gene at MOPED

Post-translational modifications for ZNF624 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF624 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF624 Gene

Domains for ZNF624 Gene

Gene Families for ZNF624 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF624 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9P2J8

UniProtKB/Swiss-Prot:

ZN624_HUMAN :
  • Q9P2J8
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 21 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF624: view

Function for ZNF624 Gene

Molecular function for ZNF624 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF624 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF624: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF624 Gene

Localization for ZNF624 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF624 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF624 Gene COMPARTMENTS Subcellular localization image for ZNF624 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF624 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF624: view

Pathways for ZNF624 Gene

SuperPathways for ZNF624 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF624: view

Pathways by source for ZNF624 Gene

2 Reactome pathways for ZNF624 Gene

Interacting Proteins for ZNF624 Gene

Gene Ontology (GO) - Biological Process for ZNF624 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF624: view

Transcripts for ZNF624 Gene

mRNA/cDNA for ZNF624 Gene

(9) Selected AceView cDNA sequences:
(4) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF624 Gene

Zinc finger protein 624:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF624 Gene

No ASD Table

Relevant External Links for ZNF624 Gene

GeneLoc Exon Structure for
ZNF624
ECgene alternative splicing isoforms for
ZNF624

Expression for ZNF624 Gene

mRNA expression in normal human tissues for ZNF624 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF624 Gene

SOURCE GeneReport for Unigene cluster for ZNF624 Gene Hs.128078

genes like me logo Genes that share expressions with ZNF624: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF624 Gene

Orthologs for ZNF624 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF624 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF624 35
  • 99.65 (n)
  • 99.31 (a)
ZNF624 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF624 36
  • 49 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF624 35
  • 90.66 (n)
  • 91.49 (a)
ZNF624 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm14124 36
  • 44 (a)
ManyToMany
Gm3055 35
  • 61.99 (n)
  • 53.46 (a)
Zfp26 16
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 51 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC100909569 35
  • 61.22 (n)
  • 52.94 (a)
chicken
(Gallus gallus)
Aves LOC100858477 35
  • 54.11 (n)
  • 46.58 (a)
Species with no ortholog for ZNF624:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF624 Gene

ENSEMBL:
Gene Tree for ZNF624 (if available)
TreeFam:
Gene Tree for ZNF624 (if available)

Paralogs for ZNF624 Gene

Selected SIMAP similar genes for ZNF624 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF624: view

Variants for ZNF624 Gene

Sequence variations from dbSNP and Humsavar for ZNF624 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs3813766 -- 16,654,292(+) AAATT(A/C)TTCGA upstream-variant-2KB
rs4239135 -- 16,635,691(+) acatg(C/T)tattg intron-variant
rs4287607 -- 16,623,432(+) GGCTT(A/G)AATTA reference, missense
rs4352086 -- 16,641,149(+) aacat(C/T)atcaa intron-variant
rs4447465 -- 16,635,151(+) CTTAT(A/C)TAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF624 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV Deletion 23290073
dgv928e1 CNV Complex 17122850

Relevant External Links for ZNF624 Gene

HapMap Linkage Disequilibrium report
ZNF624
Human Gene Mutation Database (HGMD)
ZNF624

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF624 Gene

Disorders for ZNF624 Gene

Relevant External Links for ZNF624

Genetic Association Database (GAD)
ZNF624
Human Genome Epidemiology (HuGE) Navigator
ZNF624
genes like me logo Genes that share disorders with ZNF624: view

No data available for UniProtKB/Swiss-Prot for ZNF624 Gene

Publications for ZNF624 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PMID: 20453000) Liu C.Y. … Christiani D.C. (Carcinogenesis 2010) 3 48
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZNF624 Gene

Sources for ZNF624 Gene

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