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Aliases for ZNF623 Gene

Aliases for ZNF623 Gene

  • Zinc Finger Protein 623 2 3
  • KIAA0628 4

External Ids for ZNF623 Gene

Summaries for ZNF623 Gene

GeneCards Summary for ZNF623 Gene

ZNF623 (Zinc Finger Protein 623) is a Protein Coding gene. An important paralog of this gene is ZNF16.

UniProtKB/Swiss-Prot for ZNF623 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF623 Gene

Genomics for ZNF623 Gene

Genomic Location for ZNF623 Gene

Start:
143,636,013 bp from pter
End:
143,656,418 bp from pter
Size:
20,406 bases
Orientation:
Plus strand

Genomic View for ZNF623 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF623 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF623 Gene

Regulatory Elements for ZNF623 Gene

Proteins for ZNF623 Gene

  • Protein details for ZNF623 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75123-ZN623_HUMAN
    Recommended name:
    Zinc finger protein 623
    Protein Accession:
    O75123
    Secondary Accessions:
    • A4FU80
    • B4DGP3
    • E7ENV5

    Protein attributes for ZNF623 Gene

    Size:
    536 amino acids
    Molecular mass:
    61392 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA31603.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAG57854.1; Type=Frameshift; Positions=467; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF623 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF623 Gene

Proteomics data for ZNF623 Gene at MOPED

Post-translational modifications for ZNF623 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF623 Gene

No data available for DME Specific Peptides for ZNF623 Gene

Domains for ZNF623 Gene

Gene Families for ZNF623 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF623 Gene

UniProtKB/Swiss-Prot:

ZN623_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • O75123
Similarity:
  • Contains 13 C2H2-type zinc fingers.:
    • O75123
genes like me logo Genes that share domains with ZNF623: view

Function for ZNF623 Gene

Molecular function for ZNF623 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF623 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF623: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF623 Gene

Localization for ZNF623 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF623 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF623 Gene COMPARTMENTS Subcellular localization image for ZNF623 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF623 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF623: view

Pathways for ZNF623 Gene

SuperPathways for ZNF623 Gene

No Data Available

Interacting Proteins for ZNF623 Gene

Gene Ontology (GO) - Biological Process for ZNF623 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF623: view

No data available for Pathways by source for ZNF623 Gene

Transcripts for ZNF623 Gene

mRNA/cDNA for ZNF623 Gene

(5) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF623 Gene

Zinc finger protein 623:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF623 Gene

No ASD Table

Relevant External Links for ZNF623 Gene

GeneLoc Exon Structure for
ZNF623
ECgene alternative splicing isoforms for
ZNF623

Expression for ZNF623 Gene

mRNA expression in normal human tissues for ZNF623 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZNF623 Gene

SOURCE GeneReport for Unigene cluster for ZNF623 Gene Hs.694018

genes like me logo Genes that share expressions with ZNF623: view

Orthologs for ZNF623 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF623 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF623 36
  • 99.44 (n)
  • 99.07 (a)
ZNF623 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF623 36
  • 78.93 (n)
  • 81.3 (a)
ZNF623 37
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF623 36
  • 85.31 (n)
  • 84.91 (a)
ZNF623 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp623 36
  • 80.82 (n)
  • 83.27 (a)
Zfp623 16
Zfp623 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 42 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC102547932 36
  • 80.61 (n)
  • 82.04 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 40 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii BX927130.1 37
  • 39 (a)
OneToMany
Species with no ortholog for ZNF623:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF623 Gene

ENSEMBL:
Gene Tree for ZNF623 (if available)
TreeFam:
Gene Tree for ZNF623 (if available)

Paralogs for ZNF623 Gene

Paralogs for ZNF623 Gene

Selected SIMAP similar genes for ZNF623 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF623: view

Variants for ZNF623 Gene

Sequence variations from dbSNP and Humsavar for ZNF623 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs896936 -- 143,643,299(-) CAAAG(A/C)TGCAA intron-variant
rs896937 -- 143,643,149(-) agccg(C/T)cccta intron-variant
rs921669 -- 143,653,177(-) CCACT(A/G)TCCAT utr-variant-3-prime
rs1540558 -- 143,636,084(-) CCCGC(C/G)GGCGC upstream-variant-2KB, utr-variant-5-prime
rs1869435 -- 143,652,963(-) TGAGG(A/G)CACAT utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF623 Gene

Variant ID Type Subtype PubMed ID
nsv891676 CNV Loss 21882294
dgv7932n71 CNV Loss 21882294
dgv7934n71 CNV Loss 21882294
dgv7935n71 CNV Loss 21882294
nsv466004 CNV Loss 19166990
nsv831488 CNV Loss 17160897
nsv6439 CNV Loss 18451855
esv4725 CNV Deletion 18987735
esv5538 CNV Loss 19470904
esv1406298 CNV Deletion 17803354
esv2738024 CNV Deletion 23290073
nsv6440 CNV Insertion 18451855

Relevant External Links for ZNF623 Gene

HapMap Linkage Disequilibrium report
ZNF623

Disorders for ZNF623 Gene

No disorders were found for ZNF623 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF623 Gene

Publications for ZNF623 Gene

  1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9734811) Ishikawa K. … Ohara O. (DNA Res. 1998) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for ZNF623 Gene

Sources for ZNF623 Gene

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