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Aliases for ZNF620 Gene

Aliases for ZNF620 Gene

  • Zinc Finger Protein 620 2 3 5

External Ids for ZNF620 Gene

Previous GeneCards Identifiers for ZNF620 Gene

  • GC03P040509
  • GC03P040522

Summaries for ZNF620 Gene

GeneCards Summary for ZNF620 Gene

ZNF620 (Zinc Finger Protein 620) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF619.

UniProtKB/Swiss-Prot for ZNF620 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF620 Gene

Genomics for ZNF620 Gene

Regulatory Elements for ZNF620 Gene

Enhancers for ZNF620 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G041116 1.3 Ensembl ENCODE 11.3 +612.8 612834 2.5 PKNOX1 CREB3L1 ZFP64 ARID4B DMAP1 FEZF1 ZNF2 SLC30A9 ZNF766 CBX5 ZNF619 ZNF620 CTNNB1 ENSG00000233919 LOC105377045
GH03G041158 1 ENCODE 11.3 +654.6 654622 2.4 HDGF PKNOX1 ZNF493 ZFP64 FEZF1 ZNF2 GATA2 FOS KLF7 ZNF202 ZNF619 ZNF620 CTNNB1 ENSG00000233919 LOC105377045
GH03G040464 1 ENCODE 10.7 -40.2 -40243 0.9 HNRNPUL1 HDGF FOXA2 PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 ENTPD3-AS1 RNU5B-2P ZNF620 RPL14 PIR56082
GH03G040580 0.7 ENCODE 12 +75.7 75726 0.1 CTCF IRF2 ZSCAN26 TEAD4 RAD21 TEAD3 ZNF316 ZNF547 ZNF143 SMC3 ZNF620 CTNNB1 GC03M040586 ZNF621
GH03G040503 1.1 ENCODE 0.7 +0.4 441 3.0 PKNOX1 FOXA2 CREB3L1 SIN3A ARID4B FEZF1 DMAP1 ZNF2 YY1 ZNF143 ZNF619 RPL14 ENTPD3-AS1 ZNF620 ZNF621
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF620 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF620 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000151177 1311 1401 FOXA2 ATF1 CREB3L1 SIN3A ARID4B DMAP1 ZNF2 YY1 GLIS2 ELK1

Genomic Location for ZNF620 Gene

Chromosome:
3
Start:
40,504,989 bp from pter
End:
40,518,736 bp from pter
Size:
13,748 bases
Orientation:
Plus strand

Genomic View for ZNF620 Gene

Genes around ZNF620 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF620 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF620 Gene

Proteins for ZNF620 Gene

  • Protein details for ZNF620 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNG0-ZN620_HUMAN
    Recommended name:
    Zinc finger protein 620
    Protein Accession:
    Q6ZNG0
    Secondary Accessions:
    • Q8N223

    Protein attributes for ZNF620 Gene

    Size:
    422 amino acids
    Molecular mass:
    48503 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF620 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF620 Gene

Post-translational modifications for ZNF620 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF620 Gene

Domains & Families for ZNF620 Gene

Gene Families for ZNF620 Gene

Protein Domains for ZNF620 Gene

Suggested Antigen Peptide Sequences for ZNF620 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZNG0

UniProtKB/Swiss-Prot:

ZN620_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF620: view

Function for ZNF620 Gene

Molecular function for ZNF620 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF620: view
genes like me logo Genes that share phenotypes with ZNF620: view

Animal Model Products

CRISPR Products

miRNA for ZNF620 Gene

miRTarBase miRNAs that target ZNF620

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF620 Gene

Localization for ZNF620 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF620 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF620 gene
Compartment Confidence
nucleus 5
plasma membrane 2
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF620: view

Pathways & Interactions for ZNF620 Gene

SuperPathways for ZNF620 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF620: view

Pathways by source for ZNF620 Gene

2 Reactome pathways for ZNF620 Gene

Interacting Proteins for ZNF620 Gene

Gene Ontology (GO) - Biological Process for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF620: view

No data available for SIGNOR curated interactions for ZNF620 Gene

Drugs & Compounds for ZNF620 Gene

No Compound Related Data Available

Transcripts for ZNF620 Gene

Unigene Clusters for ZNF620 Gene

Zinc finger protein 620:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF620 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP3: - - - - -
SP4: - - - -

Relevant External Links for ZNF620 Gene

GeneLoc Exon Structure for
ZNF620
ECgene alternative splicing isoforms for
ZNF620

Expression for ZNF620 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF620 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF620 Gene:

ZNF620

SOURCE GeneReport for Unigene cluster for ZNF620 Gene:

Hs.581541

Evidence on tissue expression from TISSUES for ZNF620 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF620: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF620 Gene

Orthologs for ZNF620 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF620 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF620 34 35
  • 99.61 (n)
dog
(Canis familiaris)
Mammalia ZNF621 34
  • 86.78 (n)
ZNF620 35
  • 71 (a)
OneToOne
Species where no ortholog for ZNF620 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF620 Gene

ENSEMBL:
Gene Tree for ZNF620 (if available)
TreeFam:
Gene Tree for ZNF620 (if available)

Paralogs for ZNF620 Gene

Paralogs for ZNF620 Gene

(491) SIMAP similar genes for ZNF620 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF620 Gene

genes like me logo Genes that share paralogs with ZNF620: view

Variants for ZNF620 Gene

Sequence variations from dbSNP and Humsavar for ZNF620 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000013528 -- 40,504,501(+) ATAGG(C/T)TTAGC upstream-variant-2KB, utr-variant-5-prime
rs1000125293 -- 40,511,883(+) CTCCA(C/T)GTTGG intron-variant
rs1000197574 -- 40,500,809(+) ACAGA(G/T)CTAAT upstream-variant-2KB
rs1000590552 -- 40,516,411(+) AGAGA(A/G)TCCAC reference, missense
rs1000665546 -- 40,517,887(+) ACATT(A/C)CTAGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF620 Gene

Variant ID Type Subtype PubMed ID
nsv818137 CNV loss 17921354

Variation tolerance for ZNF620 Gene

Residual Variation Intolerance Score: 48.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.04; 50.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF620 Gene

Human Gene Mutation Database (HGMD)
ZNF620
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF620

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF620 Gene

Disorders for ZNF620 Gene

Relevant External Links for ZNF620

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF620

No disorders were found for ZNF620 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF620 Gene

Publications for ZNF620 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. (PMID: 16368877) Choy K.W. … Pang C.P. (Physiol. Genomics 2006) 3 64

Products for ZNF620 Gene

Sources for ZNF620 Gene

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