ZNF620 Gene
protein-coding GIFtS: 47
GCID: GC03P040522
|
|
zinc finger protein 620
| |
Aliases
for ZNF620 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6201 2 | | MGC508361 |
Export aliases for ZNF620 gene to outside databasesPrevious GC identifer: GC03P040509 |
Summaries
for ZNF620 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN620_HUMAN, Q6ZNG0Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF620 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF620 gene promoter:
AREB6 C/EBPbeta Ik-2 Ik-3 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF620
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF620 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p22.1 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p21.33ZNF620 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P040522: view genomic region
(about GC identifiers)
Start:
|
40,547,483 bp from pter |
End:
|
40,560,227 bp from pter |
Size:
|
12,745 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF620 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN620_HUMAN, Q6ZNG0 (See
protein sequence)Recommended Name: Zinc finger protein 620 Size: 422 amino acids; 48503 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q8N223Alternative splicing: 2 isoforms: Q6ZNG0-1 Q6ZNG0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF620: NX_Q6ZNG0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZNG0
ZNF620 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001243096.1 NP_001243097.1 NP_787084.1
ENSEMBL proteins: ENSP00000406156 ENSP00000322265 ENSP00000391472 ENSP00000406967 Reactome Protein details: Q6ZNG0
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF620 for ontologies About GeneDecksing
ZNF620 Antibody Products:
Assay Products for ZNF620: |
Protein
Domains /
Families
for ZNF620 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF620 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZNG0ProtoNet protein and cluster: Q6ZNG0 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN620_HUMAN, Q6ZNG0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 8 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF620 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN620_HUMAN, Q6ZNG0Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF620 (NM_175888) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF620 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF620 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF620 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF620 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF620 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF620
ZNF620 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF620
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for ZNF620 (Q6ZNG03 ENSP000003222654) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF620 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF620 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF620
Search CenterWatch for drugs/clinical trials and news about ZNF620 / ZN620
|
Transcripts
for ZNF620 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF620 gene (3 alternative transcripts): NM_001256167.1 NM_001256168.1 NM_175888.3 Unigene Cluster for ZNF620: Zinc finger protein 620 Hs.581541 [show with all ESTs]Unigene Representative Sequence: NM_1758884 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000420891 ENST00000314529(uc003ckk.3 uc003ckl.3) ENST00000418905
ENST00000433723
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF620 (NM_175888) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF620 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF620 |
Additional cDNA sequence: AK093599.1 AK131232.1 BC044953.1 4 DOTS entries: DT.40217820 DT.91787118 DT.40231477 DT.91703399 24/32 AceView cDNA sequences (see all 32): BG289896 AW103006 BU167504 NM_175888 AK131232 BE866874 NM_173656 BM922232 AK075245 CO250237 AX748220 BQ222863 AI948629 BC044953 AK093599 CO250062 BE019346 CD236827 CO247840 AI696883 AW748345 CO250098 CO247771 W20056
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF620 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | - | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for ZNF620
|
Expression
for ZNF620 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF620 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAATGTTT
About this image
See ZNF620 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF620
SOURCE GeneReport for Unigene cluster: Hs.581541
SABiosciences Custom PCR Arrays for ZNF620
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF620
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF620 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF620 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF620 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF620 |
Orthologs
for ZNF620 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF620 gene from 1/4 species (see all 4) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
18(a) |
1 → many |
GroupUn.197(18775-21878) |
ENSEMBL Gene Tree for ZNF620 (if available)
TreeFam Gene Tree for ZNF620 (if available) |
Paralogs
for ZNF620 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF620 gene
- ZNF6212 ZNF192 ENSG000002616112 ZNF6622 ZNF6192
18/476 SIMAP similar genes for ZNF620 using alignment to 3 protein entries: ZN620_HUMAN (see all proteins)
(see all similar genes):PFKFB3 TUBA1C SH2B3 ZSCAN31 ZNF300P1 ZNF331
DKFZp666C237 SMYD4 LSM12 ZNF232 DKFZp686M04222 GLI4
ZNF345 zf30 DKFZp313M0722 HZF36 ZNF204 ZNF323
ZNF620 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for ZNF620
PGOHUM00000242536 PGOHUM00000237204 PGOHUM00000238003 PGOHUM00000238004
|
Genomic Variants
for ZNF620 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF620 (40547483 - 40560227 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF620
1 CNV: 9992 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF620 |
|
Disorders
/ Diseases
for ZNF620 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF620 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF620 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF620) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1 Nozawa R.S....Obuse C. (2010)
- Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. (PubMed id 16368877)1 Choy K.W....Pang C.P. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for ZNF620 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF620 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF620 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF620 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF620 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF620 gene:
Search GeneIP for patents involving ZNF620
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF620 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF620 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF620 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF620 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF620 | | OriGene 3'-UTR Clone for ZNF620 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF620 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF620 | | OriGene Custom Protein Services for ZNF620 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF620 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF620 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF620 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF620 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF620 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF620 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF620 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF620 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF620 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF620 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF620 |
|
|
|
|
