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Aliases for ZNF620 Gene

Aliases for ZNF620 Gene

  • Zinc Finger Protein 620 2 3

External Ids for ZNF620 Gene

Summaries for ZNF620 Gene

GeneCards Summary for ZNF620 Gene

ZNF620 (Zinc Finger Protein 620) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF662.

UniProtKB/Swiss-Prot for ZNF620 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF620 Gene

Genomics for ZNF620 Gene

Genomic Location for ZNF620 Gene

Start:
40,505,959 bp from pter
End:
40,518,736 bp from pter
Size:
12,778 bases
Orientation:
Plus strand

Genomic View for ZNF620 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF620 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF620 Gene

Regulatory Elements for ZNF620 Gene

Proteins for ZNF620 Gene

  • Protein details for ZNF620 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNG0-ZN620_HUMAN
    Recommended name:
    Zinc finger protein 620
    Protein Accession:
    Q6ZNG0
    Secondary Accessions:
    • Q8N223

    Protein attributes for ZNF620 Gene

    Size:
    422 amino acids
    Molecular mass:
    48503 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF620 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF620 Gene

Proteomics data for ZNF620 Gene at MOPED

Post-translational modifications for ZNF620 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF620 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF620 Gene

Domains for ZNF620 Gene

Gene Families for ZNF620 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN620_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q6ZNG0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q6ZNG0
Similarity:
  • Contains 8 C2H2-type zinc fingers.:
    • Q6ZNG0
genes like me logo Genes that share domains with ZNF620: view

Function for ZNF620 Gene

Molecular function for ZNF620 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF620: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF620 Gene

Localization for ZNF620 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF620 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF620 Gene COMPARTMENTS Subcellular localization image for ZNF620 gene
Compartment Confidence
nucleus 4
cytosol 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF620: view

Pathways for ZNF620 Gene

SuperPathways for ZNF620 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF620: view

Pathways by source for ZNF620 Gene

2 Reactome pathways for ZNF620 Gene

Interacting Proteins for ZNF620 Gene

Gene Ontology (GO) - Biological Process for ZNF620 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF620: view

Transcripts for ZNF620 Gene

Unigene Clusters for ZNF620 Gene

Zinc finger protein 620:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF620 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP3: - - - - -
SP4: - - - -

Relevant External Links for ZNF620 Gene

GeneLoc Exon Structure for
ZNF620
ECgene alternative splicing isoforms for
ZNF620

Expression for ZNF620 Gene

mRNA expression in normal human tissues for ZNF620 Gene

SOURCE GeneReport for Unigene cluster for ZNF620 Gene Hs.581541

genes like me logo Genes that share expressions with ZNF620: view

Orthologs for ZNF620 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF620 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF620 36
  • 99.61 (n)
  • 99.53 (a)
ZNF620 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF620 37
  • 71 (a)
OneToOne
ZNF621 36
  • 86.78 (n)
  • 82.69 (a)
mouse
(Mus musculus)
Mammalia Zfp947 16
Species with no ortholog for ZNF620:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF620 Gene

ENSEMBL:
Gene Tree for ZNF620 (if available)
TreeFam:
Gene Tree for ZNF620 (if available)

Paralogs for ZNF620 Gene

Paralogs for ZNF620 Gene

Selected SIMAP similar genes for ZNF620 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF620 Gene

genes like me logo Genes that share paralogs with ZNF620: view

Variants for ZNF620 Gene

Sequence variations from dbSNP and Humsavar for ZNF620 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs4973907 -- 40,517,587(+) ttcaa(C/G)agcaa utr-variant-3-prime, downstream-variant-500B
rs6599107 -- 40,513,579(+) ggtcg(C/T)agtga intron-variant
rs6768538 -- 40,518,699(+) ctggg(C/T)gacag downstream-variant-500B
rs6790578 -- 40,511,425(+) CCTGA(C/T)CCTCT intron-variant
rs6792325 -- 40,507,337(+) ccccc(A/G)ccttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF620 Gene

Variant ID Type Subtype PubMed ID
nsv876716 CNV Gain 21882294
nsv818137 CNV Loss 17921354

Relevant External Links for ZNF620 Gene

HapMap Linkage Disequilibrium report
ZNF620

Disorders for ZNF620 Gene

No disorders were found for ZNF620 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF620 Gene

Publications for ZNF620 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. (PMID: 16368877) Choy K.W. … Pang C.P. (Physiol. Genomics 2006) 3
  5. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3

Products for ZNF620 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF620
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF620
    • Block miRNA regulation of ZNF620 using miScript Target Protectors

    Sources for ZNF620 Gene

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