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Aliases for ZNF619 Gene

Aliases for ZNF619 Gene

  • Zinc Finger Protein 619 2 3 5

External Ids for ZNF619 Gene

Previous GeneCards Identifiers for ZNF619 Gene

  • GC03P040480
  • GC03P040493

Summaries for ZNF619 Gene

GeneCards Summary for ZNF619 Gene

ZNF619 (Zinc Finger Protein 619) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000261611.

UniProtKB/Swiss-Prot for ZNF619 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF619 Gene

Genomics for ZNF619 Gene

Regulatory Elements for ZNF619 Gene

Enhancers for ZNF619 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF619 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF619 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF619 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF619 Gene

40,477,113 bp from pter
40,490,237 bp from pter
13,125 bases
Plus strand

Genomic View for ZNF619 Gene

Genes around ZNF619 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF619 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF619 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF619 Gene

Proteins for ZNF619 Gene

  • Protein details for ZNF619 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 619
    Protein Accession:
    Secondary Accessions:
    • B4E271
    • C9JRN5
    • D4PHA2
    • E9PCD9

    Protein attributes for ZNF619 Gene

    560 amino acids
    Molecular mass:
    63322 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF619 Gene


neXtProt entry for ZNF619 Gene

Proteomics data for ZNF619 Gene at MOPED

Post-translational modifications for ZNF619 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF619 Gene

Domains & Families for ZNF619 Gene

Gene Families for ZNF619 Gene

Protein Domains for ZNF619 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF619: view

Function for ZNF619 Gene

Molecular function for ZNF619 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF619: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF619 Gene

Localization for ZNF619 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF619 Gene

Subcellular locations from

Jensen Localization Image for ZNF619 Gene COMPARTMENTS Subcellular localization image for ZNF619 gene
Compartment Confidence
nucleus 5
cytoskeleton 2
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF619 Gene

Pathways & Interactions for ZNF619 Gene

SuperPathways for ZNF619 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF619: view

Pathways by source for ZNF619 Gene

2 Reactome pathways for ZNF619 Gene

Interacting Proteins for ZNF619 Gene

Gene Ontology (GO) - Biological Process for ZNF619 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF619: view

No data available for SIGNOR curated interactions for ZNF619 Gene

Drugs & Compounds for ZNF619 Gene

No Compound Related Data Available

Transcripts for ZNF619 Gene

Unigene Clusters for ZNF619 Gene

Zinc finger protein 619:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF619 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b
SP2: -

Relevant External Links for ZNF619 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF619 Gene

mRNA expression in normal human tissues for ZNF619 Gene

Protein differential expression in normal tissues from HIPED for ZNF619 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF619 Gene

SOURCE GeneReport for Unigene cluster for ZNF619 Gene Hs.407159

genes like me logo Genes that share expression patterns with ZNF619: view

Protein tissue co-expression partners for ZNF619 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF619 Gene

Orthologs for ZNF619 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF619 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF619 35
  • 82.04 (n)
  • 75.39 (a)
ZNF621 36
  • 38 (a)
(Canis familiaris)
Mammalia ZNF619 35
  • 80.62 (n)
  • 72.44 (a)
ZNF619 36
  • 70 (a)
(Pan troglodytes)
Mammalia ZNF619 35
  • 99.19 (n)
  • 98.09 (a)
ZNF619 36
  • 94 (a)
Species with no ortholog for ZNF619:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF619 Gene

Gene Tree for ZNF619 (if available)
Gene Tree for ZNF619 (if available)

Paralogs for ZNF619 Gene

Paralogs for ZNF619 Gene

(521) SIMAP similar genes for ZNF619 Gene using alignment to 5 proteins: Pseudogenes for ZNF619 Gene

genes like me logo Genes that share paralogs with ZNF619: view

Variants for ZNF619 Gene

Sequence variations from dbSNP and Humsavar for ZNF619 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs6599105 -- 40,490,042(+) ctcca(C/T)gatgg nc-transcript-variant, utr-variant-3-prime
rs4553952 -- 40,477,938(+) CTTTT(C/T)CAAAC intron-variant, nc-transcript-variant, utr-variant-5-prime
rs6762251 -- 40,489,645(+) CCTGA(A/G)TATAG nc-transcript-variant, utr-variant-3-prime
rs4571217 -- 40,480,482(+) TTACA(A/G)TGATG intron-variant
rs9827958 -- 40,481,289(+) CAGAA(G/T)GATGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF619 Gene

Variant ID Type Subtype PubMed ID
nsv876716 CNV Gain 21882294
nsv818137 CNV Loss 17921354
nsv876717 CNV Loss 21882294

Variation tolerance for ZNF619 Gene

Residual Variation Intolerance Score: 61.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.08; 68.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF619 Gene

Disorders for ZNF619 Gene

Relevant External Links for ZNF619

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF619 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF619 Gene

Publications for ZNF619 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (PMID: 23284306) Xie L. … Green M.R. (PLoS Genet. 2012) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ZNF619 Gene

Sources for ZNF619 Gene