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Aliases for ZNF619 Gene

Aliases for ZNF619 Gene

  • Zinc Finger Protein 619 2 3

External Ids for ZNF619 Gene

Summaries for ZNF619 Gene

GeneCards Summary for ZNF619 Gene

ZNF619 (Zinc Finger Protein 619) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF662.

UniProtKB/Swiss-Prot for ZNF619 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF619 Gene

Genomics for ZNF619 Gene

Genomic Location for ZNF619 Gene

Start:
40,477,113 bp from pter
End:
40,490,237 bp from pter
Size:
13,125 bases
Orientation:
Plus strand

Genomic View for ZNF619 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF619 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF619 Gene

Regulatory Elements for ZNF619 Gene

Proteins for ZNF619 Gene

  • Protein details for ZNF619 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N2I2-ZN619_HUMAN
    Recommended name:
    Zinc finger protein 619
    Protein Accession:
    Q8N2I2
    Secondary Accessions:
    • B4E271
    • C9JRN5
    • D4PHA2
    • E9PCD9

    Protein attributes for ZNF619 Gene

    Size:
    560 amino acids
    Molecular mass:
    63322 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF619 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF619 Gene

Proteomics data for ZNF619 Gene at MOPED

Post-translational modifications for ZNF619 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF619 Gene

No data available for DME Specific Peptides for ZNF619 Gene

Domains for ZNF619 Gene

Gene Families for ZNF619 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF619 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N2I2

UniProtKB/Swiss-Prot:

ZN619_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8N2I2
Similarity:
  • Contains 10 C2H2-type zinc fingers.:
    • Q8N2I2
genes like me logo Genes that share domains with ZNF619: view

Function for ZNF619 Gene

Molecular function for ZNF619 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF619 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF619: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF619 Gene

Localization for ZNF619 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF619 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF619 Gene COMPARTMENTS Subcellular localization image for ZNF619 gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZNF619 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF619: view

Pathways for ZNF619 Gene

SuperPathways for ZNF619 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF619: view

Pathways by source for ZNF619 Gene

2 Reactome pathways for ZNF619 Gene

Interacting Proteins for ZNF619 Gene

Gene Ontology (GO) - Biological Process for ZNF619 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF619: view

Transcripts for ZNF619 Gene

Unigene Clusters for ZNF619 Gene

Zinc finger protein 619:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF619 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b
SP1:
SP2: -

Relevant External Links for ZNF619 Gene

GeneLoc Exon Structure for
ZNF619
ECgene alternative splicing isoforms for
ZNF619

Expression for ZNF619 Gene

mRNA expression in normal human tissues for ZNF619 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF619 Gene

SOURCE GeneReport for Unigene cluster for ZNF619 Gene Hs.407159

genes like me logo Genes that share expressions with ZNF619: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF619 Gene

Orthologs for ZNF619 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF619 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF619 35
  • 99.19 (n)
  • 98.09 (a)
ZNF619 36
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF619 35
  • 82.04 (n)
  • 75.39 (a)
ZNF621 36
  • 38 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF619 35
  • 80.62 (n)
  • 72.44 (a)
ZNF619 36
  • 70 (a)
OneToOne
Species with no ortholog for ZNF619:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF619 Gene

ENSEMBL:
Gene Tree for ZNF619 (if available)
TreeFam:
Gene Tree for ZNF619 (if available)

Paralogs for ZNF619 Gene

Paralogs for ZNF619 Gene

Selected SIMAP similar genes for ZNF619 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF619 Gene

genes like me logo Genes that share paralogs with ZNF619: view

Variants for ZNF619 Gene

Sequence variations from dbSNP and Humsavar for ZNF619 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs4128740 -- 40,478,041(-) TATCT(G/T)TTCTG intron-variant
rs4553952 -- 40,477,938(+) CTTTT(C/T)CAAAC utr-variant-5-prime
rs4571217 -- 40,480,482(+) TTACA(A/G)TGATG intron-variant
rs4974029 -- 40,479,827(+) CAGTT(C/G)TGACA intron-variant
rs5848567 -- 40,485,318(+) TTTTT(-/T/TT)GGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF619 Gene

Variant ID Type Subtype PubMed ID
nsv876716 CNV Gain 21882294
nsv818137 CNV Loss 17921354
nsv876717 CNV Loss 21882294

Relevant External Links for ZNF619 Gene

HapMap Linkage Disequilibrium report
ZNF619

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF619 Gene

Disorders for ZNF619 Gene

No disorders were found for ZNF619 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF619 Gene

Publications for ZNF619 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4
  3. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF619 Gene

Sources for ZNF619 Gene

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