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Aliases for ZNF618 Gene

Aliases for ZNF618 Gene

  • Zinc Finger Protein 618 2 3
  • Neural Precursor Cell Expressed, Developmentally Down-Regulated 10 3
  • Developmentally Down-Regulated 10 2
  • Neural Precursor Cell Expressed 2
  • KIAA1952 4
  • FP13169 3
  • NEDD10 3

External Ids for ZNF618 Gene

Previous GeneCards Identifiers for ZNF618 Gene

  • GC09P112015
  • GC09P113718
  • GC09P115678
  • GC09P116638
  • GC09P086337

Summaries for ZNF618 Gene

GeneCards Summary for ZNF618 Gene

ZNF618 (Zinc Finger Protein 618) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF618 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF618 Gene

Genomics for ZNF618 Gene

Regulatory Elements for ZNF618 Gene

Genomic Location for ZNF618 Gene

Start:
113,876,282 bp from pter
End:
114,056,595 bp from pter
Size:
180,314 bases
Orientation:
Plus strand

Genomic View for ZNF618 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF618 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF618 Gene

Proteins for ZNF618 Gene

  • Protein details for ZNF618 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T7W0-ZN618_HUMAN
    Recommended name:
    Zinc finger protein 618
    Protein Accession:
    Q5T7W0
    Secondary Accessions:
    • B9EG82
    • Q4G0X6
    • Q5T7W1
    • Q6ZT53
    • Q7Z6B9
    • Q8TF49
    • Q96E49

    Protein attributes for ZNF618 Gene

    Size:
    954 amino acids
    Molecular mass:
    104956 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH36039.1; Type=Erroneous termination; Positions=241; Note=Translated as Glu.; Evidence={ECO:0000305}; Sequence=AAH53892.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB85538.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF618 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF618 Gene

Proteomics data for ZNF618 Gene at MOPED

Post-translational modifications for ZNF618 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF618 Gene

No data available for DME Specific Peptides for ZNF618 Gene

Domains for ZNF618 Gene

Gene Families for ZNF618 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF618 Gene

Suggested Antigen Peptide Sequences for ZNF618 Gene

Graphical View of Domain Structure for InterPro Entry

Q5T7W0

UniProtKB/Swiss-Prot:

ZN618_HUMAN :
  • Q5T7W0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF618: view

Function for ZNF618 Gene

Molecular function for ZNF618 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF618 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF618: view

Animal Model Products

CRISPR Products

miRNA for ZNF618 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF618

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF618 Gene

Localization for ZNF618 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF618 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF618 Gene COMPARTMENTS Subcellular localization image for ZNF618 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF618 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF618: view

Pathways for ZNF618 Gene

SuperPathways for ZNF618 Gene

No Data Available

Interacting Proteins for ZNF618 Gene

Gene Ontology (GO) - Biological Process for ZNF618 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF618: view

No data available for Pathways by source for ZNF618 Gene

Transcripts for ZNF618 Gene

Unigene Clusters for ZNF618 Gene

Zinc finger protein 618:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF618

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF618
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF618 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b
SP1: - - -
SP2: -
SP3:
SP4: -
SP5: - - -
SP6:

Relevant External Links for ZNF618 Gene

GeneLoc Exon Structure for
ZNF618
ECgene alternative splicing isoforms for
ZNF618

Expression for ZNF618 Gene

mRNA expression in normal human tissues for ZNF618 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF618 Gene

SOURCE GeneReport for Unigene cluster for ZNF618 Gene Hs.349208

genes like me logo Genes that share expressions with ZNF618: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF618 Gene

Orthologs for ZNF618 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF618 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF618 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF618 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF618 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp618 35
  • 88.26 (n)
  • 95.12 (a)
Zfp618 16
Zfp618 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF618 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF618 36
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF618 35
  • 80.21 (n)
  • 87.28 (a)
ZNF618 36
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF618 36
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.13236 35
zebrafish
(Danio rerio)
Actinopterygii znf618 35
  • 62.36 (n)
  • 60.31 (a)
ZNF618 36
  • 54 (a)
OneToOne
Species with no ortholog for ZNF618:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF618 Gene

ENSEMBL:
Gene Tree for ZNF618 (if available)
TreeFam:
Gene Tree for ZNF618 (if available)

Paralogs for ZNF618 Gene

No data available for Paralogs for ZNF618 Gene

Variants for ZNF618 Gene

Sequence variations from dbSNP and Humsavar for ZNF618 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs140850 -- 114,033,847(+) TGGGC(-/ACT)ACTGC intron-variant
rs700124 -- 113,964,239(-) AGAAC(C/T)GAGCC intron-variant
rs700125 -- 114,001,625(+) AATGC(A/G)TTGAA intron-variant
rs752035 -- 114,031,798(+) TGGTT(C/G)CCTGA intron-variant
rs814678 -- 113,958,071(+) ACTGA(A/G)ATTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF618 Gene

Variant ID Type Subtype PubMed ID
nsv893750 CNV Loss 21882294
nsv825055 CNV Gain 20364138
esv2738960 CNV Deletion 23290073
nsv415373 CNV Loss 16902084
esv1406827 CNV Insertion 17803354
nsv521361 CNV Gain 19592680
nsv825056 CNV Gain 20364138
nsv522429 CNV Gain 19592680
nsv523823 CNV Loss 19592680
nsv521362 CNV Loss 19592680
dgv33e196 CNV Duplication 17116639
dgv945n27 CNV Gain 19166990
nsv471319 CNV Gain 18288195
nsv528822 CNV Gain 19592680

Relevant External Links for ZNF618 Gene

HapMap Linkage Disequilibrium report
ZNF618

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF618 Gene

Disorders for ZNF618 Gene

Relevant External Links for ZNF618

Genetic Association Database (GAD)
ZNF618
Human Genome Epidemiology (HuGE) Navigator
ZNF618
genes like me logo Genes that share disorders with ZNF618: view

No data available for UniProtKB/Swiss-Prot for ZNF618 Gene

Publications for ZNF618 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PMID: 19724895) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2009) 3 48
  3. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M. … Yamada Y. (Am. J. Hypertens. 2010) 3 48
  4. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2010) 3 48
  5. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PMID: 20583170) Letra A. … Vieira A.R. (Am. J. Med. Genet. A 2010) 3 48

Products for ZNF618 Gene

Sources for ZNF618 Gene

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