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Aliases for ZNF616 Gene

Aliases for ZNF616 Gene

  • Zinc Finger Protein 616 2 3

External Ids for ZNF616 Gene

Previous GeneCards Identifiers for ZNF616 Gene

  • GC19M057310
  • GC19M057314
  • GC19M052617
  • GC19M048948

Summaries for ZNF616 Gene

GeneCards Summary for ZNF616 Gene

ZNF616 (Zinc Finger Protein 616) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF616 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF616 Gene

Genomics for ZNF616 Gene

Regulatory Elements for ZNF616 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF616 Gene

Start:
52,113,091 bp from pter
End:
52,139,938 bp from pter
Size:
26,848 bases
Orientation:
Minus strand

Genomic View for ZNF616 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF616 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF616 Gene

Proteins for ZNF616 Gene

  • Protein details for ZNF616 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AN1-ZN616_HUMAN
    Recommended name:
    Zinc finger protein 616
    Protein Accession:
    Q08AN1
    Secondary Accessions:
    • B3KRV1
    • Q0P658
    • Q658V7

    Protein attributes for ZNF616 Gene

    Size:
    781 amino acids
    Molecular mass:
    90273 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF616 Gene

Proteomics data for ZNF616 Gene at MOPED

Post-translational modifications for ZNF616 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF616 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF616 Gene

Domains for ZNF616 Gene

Gene Families for ZNF616 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF616 Gene

Suggested Antigen Peptide Sequences for ZNF616 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q08AN1

UniProtKB/Swiss-Prot:

ZN616_HUMAN :
  • Q08AN1
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 21 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF616: view

Function for ZNF616 Gene

Molecular function for ZNF616 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF616 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF616: view

Phenotypes for ZNF616 Gene

GenomeRNAi human phenotypes for ZNF616:
genes like me logo Genes that share phenotypes with ZNF616: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF616

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF616 Gene

Localization for ZNF616 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF616 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF616 Gene COMPARTMENTS Subcellular localization image for ZNF616 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF616 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF616: view

Pathways for ZNF616 Gene

SuperPathways for ZNF616 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF616: view

Pathways by source for ZNF616 Gene

2 Reactome pathways for ZNF616 Gene

Interacting Proteins for ZNF616 Gene

Gene Ontology (GO) - Biological Process for ZNF616 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF616: view

Transcripts for ZNF616 Gene

Unigene Clusters for ZNF616 Gene

Zinc finger protein 616:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF616

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF616
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF616 Gene

No ASD Table

Relevant External Links for ZNF616 Gene

GeneLoc Exon Structure for
ZNF616
ECgene alternative splicing isoforms for
ZNF616

Expression for ZNF616 Gene

mRNA expression in normal human tissues for ZNF616 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF616 Gene

SOURCE GeneReport for Unigene cluster for ZNF616 Gene Hs.645225

genes like me logo Genes that share expressions with ZNF616: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF616 Gene

Orthologs for ZNF616 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF616 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF616 35
  • 99.02 (n)
  • 97.95 (a)
ZNF616 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 46 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
LOC617476 35
  • 66.9 (n)
  • 52.43 (a)
mouse
(Mus musculus)
Mammalia Gm13247 35
  • 69.37 (n)
  • 57.14 (a)
Zfp40 16
Zfp51 36
  • 39 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
CSA.1668 36
  • 33 (a)
ManyToMany
Species with no ortholog for ZNF616:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF616 Gene

ENSEMBL:
Gene Tree for ZNF616 (if available)
TreeFam:
Gene Tree for ZNF616 (if available)

Paralogs for ZNF616 Gene

Selected SIMAP similar genes for ZNF616 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF616: view

Variants for ZNF616 Gene

Sequence variations from dbSNP and Humsavar for ZNF616 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1147 -- 52,114,116(+) ACAAG(C/T)AGTGA downstream-variant-500B, utr-variant-3-prime
rs1007485 -- 52,141,753(+) GAAAG(A/G)AAATC upstream-variant-2KB
rs1045852 -- 52,115,461(-) GCATC(A/G/T)GAGAA missense, reference
rs2278423 -- 52,139,238(-) CTCCA(C/G)TGGAA intron-variant, upstream-variant-2KB
rs3764537 - 52,115,812(-) TTCAC(A/G)TCTTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZNF616 Gene

Variant ID Type Subtype PubMed ID
dgv143e55 CNV Gain 17911159
nsv833872 CNV Loss 17160897
nsv2535 CNV Loss 18451855
esv2718780 CNV Deletion 23290073

Relevant External Links for ZNF616 Gene

HapMap Linkage Disequilibrium report
ZNF616

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF616 Gene

Disorders for ZNF616 Gene

No disorders were found for ZNF616 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF616 Gene

Publications for ZNF616 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF616 Gene

Sources for ZNF616 Gene

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