ZNF615 Gene
protein-coding GIFtS: 46
GCID: GC19M052494
|
|
zinc finger protein 615
| |
Aliases
for ZNF615 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6151 2 | | FLJ337101 |
Export aliases for ZNF615 gene to outside databasesPrevious GC identifers: GC19M057188 GC19M057191 GC19M057193 GC19M057194 GC19M057195 GC19M057196 GC19M057197 GC19M057198 GC19M057199 GC19M052469 |
Summaries
for ZNF615 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN615_HUMAN, Q8N8J6Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF615 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF615 gene promoter:
Bach1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF615
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF615 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41ZNF615 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M052494: view genomic region
(about GC identifiers)
Start:
|
52,494,588 bp from pter |
End:
|
52,511,483 bp from pter |
Size:
|
16,896 bases |
Orientation:
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minus strand |
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Proteins
for ZNF615 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN615_HUMAN, Q8N8J6 (See
protein sequence)Recommended Name: Zinc finger protein 615 Size: 731 amino acids; 83739 Da
Subcellular location: Nucleus (Potential)
Caution: It is uncertain whether Met-1 or Met-2 is the initiator
Sequence caution: Sequence=BAC87399.1; Type=Miscellaneous discrepancy; Note=aberrant splicing;
Secondary accessions: B7ZKW9 Q2M2Y6 Q5CZB0 Q6ZMT7 Q6ZRB3Alternative splicing: 3 isoforms: Q8N8J6-1 Q8N8J6-2 Q8N8J6-3 (Contains a phosphoserine at position 85. Contains a phosphotyrosine at position 89)Explore the universe of human proteins at neXtProt for ZNF615: NX_Q8N8J6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N8J6
ZNF615 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001186253.1 NP_940882.3
ENSEMBL proteins: ENSP00000375672 ENSP00000365906 Reactome Protein details: Q8N8J6
Human Recombinant Protein Products for ZNF615:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF615 for ontologies About GeneDecksing
ZNF615 Antibody Products:
Assay Products for ZNF615: |
Protein
Domains /
Families
for ZNF615 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF615 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N8J6ProtoNet protein and cluster: Q8N8J6 UniProtKB/Swiss-Prot: ZN615_HUMAN, Q8N8J6Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 19 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF615 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN615_HUMAN, Q8N8J6Function: May be involved in transcriptional regulation Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF615 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF615 (NM_198480) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF615 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF615 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF615 |
|
Pathways & Interactions
for ZNF615 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF615
ZNF615 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF615
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5 Interacting proteins for ZNF615 (Q8N8J63 ENSP000003659064) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF615 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF615 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF615
Search CenterWatch for drugs/clinical trials and news about ZNF615 / ZN615
|
Transcripts
for ZNF615 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF615 gene (2 alternative transcripts): NM_001199324.1 NM_198480.3 Unigene Cluster for ZNF615: Zinc finger protein 615 Hs.368355 [show with all ESTs]Unigene Representative Sequence: BC0538842 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000391795 ENST00000376716(uc002pyf.2 uc002pye.2 uc002pyh.2 uc010epi.2 uc002pyg.2 uc010ydg.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF615 (NM_198480) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF615 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF615 |
Additional cDNA sequence: AK091029.1 AK094071.1 AK096691.1 AK128361.1 AK131494.1 AK291734.1 AK294977.1 BC053884.1 BC105100.1 BC105102.1 BC112961.1 BC143429.1 BX647556.1 BX648594.1 CR936612.1 7 DOTS entries: DT.40238635 DT.100736776 DT.101982914 DT.101982915 DT.99984836 DT.100734734 DT.305751 24/45 AceView cDNA sequences (see all 45): AX748441 AA678644 BX647556 AK096691 Z44582 AK131494 AK094071 AA653611 CA447851 BU952608 BC053884 AA809513 NM_198480 AA385633 AI183853 CD643769 BQ230210 BX489068 AL701635 AX746740 AA443458 AK091029 AI082819 AW029100
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF615 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF615
|
Expression
for ZNF615 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF615 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TACCCTTTTG
About this image
See ZNF615 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF615
SOURCE GeneReport for Unigene cluster: Hs.368355
SABiosciences Custom PCR Arrays for ZNF615
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF615
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF615 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF615 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF615 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF615 |
Orthologs
for ZNF615 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF615 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for ZNF615 (if available)
TreeFam Gene Tree for ZNF615 (if available) |
Paralogs
for ZNF615 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF615 gene
- ZNF1752 ZNF6742 LOC1002875152 ZNF6142 ZNF4322 ZNF6132 ZNF262 ZNF3502
- ZNF812 ZNF6492 ZNF6052 ZNF5772 ZNF842 ZNF6302 ZFP372 ZNF4842
- ENSG000002296312 ZNF1822 ZNF412 ZNF2682 LOC1009964642 ZNF3002
18/527 SIMAP similar genes for ZNF615 using alignment to 6 protein entries: ZN615_HUMAN (see all proteins)
(see all similar genes):ZNF300P1 MGC12518 POM121C ZNF78L1 kr-znf3 ZNF84
ZNF432 ZNF844 ZSCAN16 ZNF436 ZNF250 ZNF66
ZNF738 PRMD9 ZNF140 HZF36 ZNF613 ZNF721
ZNF615 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF615 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF615 (52494588 - 52511483 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ZNF615
5 CNVs: 8875 4086 3195 34482 53103 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF615 |
|
Disorders
/ Diseases
for ZNF615 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF615 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF615 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF615) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for ZNF615 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF615 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF615 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF615 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF615 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF615 gene:
Search GeneIP for patents involving ZNF615
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF615 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF615 | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF615 | | | OriGene Protein Over-expression Lysate for ZNF615 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF615 | | OriGene 3'-UTR Clone for ZNF615 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF615 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF615 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF615 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF615 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF615 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF615 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF615 |
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 | | | ZNF615 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF615 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF615 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF615 |
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